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    LESS INVASIVE DEVICES AND METHODS FOR TREATMENT OF CARDIAC VALVES
    1.
    发明申请
    LESS INVASIVE DEVICES AND METHODS FOR TREATMENT OF CARDIAC VALVES 审中-公开
    较少的入侵设备和治疗心脏瓣膜的方法

    公开(公告)号：WO1996039942A1

    公开(公告)日：1996-12-19

    申请号：PCT/US1996007970

    申请日：1996-05-30

    Applicant: HEARTPORT, INC.

    Inventor： HEARTPORT, INC. ,  GARRISON, Michi, E. ,  DONLON, Brian, S. ,  DANIEL, S., Christopher ,  STEVENS, John, H.

    IPC: A61B17/00

    CPC classification number: A61F2/2427 ,  A61B17/00234 ,  A61B17/0218 ,  A61B17/0293 ,  A61B90/40 ,  A61B2017/00243 ,  A61B2090/401 ,  A61F2/2403 ,  A61F2/2448 ,  A61F2/2466 ,  A61F2/2496

    Abstract: Device and methods are provided for less invasive surgical treatment of cardiac valves whereby the need for a gross thoracotomy or median sternotomy is eliminated. In one aspect of this invention, a delivery system (10) for a cardiac valve prosthesis such as an annuloplasty ring (90) or prosthetic valve (262) includes an elongated handle (28) configured to extend into the heart through an intercostal space from outside of the chest cavity, and a prosthesis holder (100) attached to the handle for releasably holding a prosthesis. The prosthesis holder (100) is attached to the handle (28) in such a way that the holder (100), prosthesis (90) and handle (28) have a profile with a height smaller than the width of an intercostal space when the adjacent ribs are unrectrated, preferably less than about 30 mm. In a further aspect, the invention provides a method for repairing or replacing a heart valve which includes the steps of introducing a prosthesis (262) through an intercostal space and through a penetration in a wall of the heart, and securing the prosthesis (262) to an interior wall of the heart, wherein each step is carried out without cutting, removing, or significantly retracting the ribs or sternum.

    Abstract translation: 为心脏瓣膜的较少侵入性手术治疗提供了装置和方法，因此消除了对大胸廓切开术或中位胸骨切开术的需要。 在本发明的一个方面，用于心脏瓣膜假体例如瓣环成形术环（90）或人工瓣膜（262）的输送系统（10）包括细长手柄（28），其配置成通过肋间隙 以及附接到手柄上的假体保持器（100），用于可释放地保持假体。 假体保持器（100）以使得保持器（100），假体（90）和手柄（28）具有高度小于肋间空间的宽度的轮廓的方式附接到手柄（28），当该 相邻的肋是非直立的，优选小于约30mm。 在另一方面，本发明提供了一种修复或替换心脏瓣膜的方法，其包括以下步骤：将假体（262）通过肋间空间引入穿过心脏的壁，并固定假体（262） 到心脏的内壁，其中每个步骤在不切割，移除或显着缩回肋骨或胸骨的情况下进行。

    CARDIOPLEGIA CATHETER SYSTEM
    2.
    发明申请
    CARDIOPLEGIA CATHETER SYSTEM 审中-公开
    CARDIOPLEGIA导管系统

    公开(公告)号：WO1996017644A1

    公开(公告)日：1996-06-13

    申请号：PCT/US1995015014

    申请日：1995-11-21

    Applicant: HEARTPORT, INC.

    Inventor： HEARTPORT, INC. ,  ST. GOAR, Frederick, G. ,  PETERS, William, S. ,  EVARD, Philip, C. ,  BOYD, Stephen, W. ,  ADAMS, Craig, L. ,  MUELLER, Richard, L., Jr. ,  STEVENS, John, H.

    IPC: A61M29/00

    CPC classification number: A61M25/0068 ,  A61B2017/00243 ,  A61B2018/00232 ,  A61B2018/00261 ,  A61F2/2427 ,  A61M1/3653 ,  A61M1/3659 ,  A61M25/0041 ,  A61M25/005 ,  A61M25/008 ,  A61M25/01 ,  A61M25/0125 ,  A61M25/0662 ,  A61M25/10 ,  A61M25/1002 ,  A61M2025/0031 ,  A61M2025/0034 ,  A61M2025/0036 ,  A61M2025/004 ,  A61M2025/0057 ,  A61M2025/0078 ,  A61M2025/0087 ,  A61M2025/028 ,  A61M2025/1047 ,  A61M2025/1077 ,  A61M2205/11 ,  A61M2205/366 ,  A61M2210/125

    Abstract: A catheter system is provided for accessing the coronary ostia (176, 180) transluminal from a peripheral arterial access site, such as the femoral artery, and for inducing cardioplegia arrest by direct infusion of cardioplegia solution into the coronary arteries. In a first embodiment, the catheter system is in the form of a single perfusion catheter (20) with multiple distal branches (24, 26, 28) for engaging the coronary ostia (176, 180). In a second embodiment, multiple perfusion catheters (82, 84) are delivered to the coronary ostia (176, 180) through a single arterial cannula (104). In a third embodiment, multiple perfusion catheters (112, 114, 116) are delivered to the coronary ostia (176, 180) through a single guiding catheter (126). In a fourth embodiment, multiple catheters (140, 142, 144) are delivered to the coronary ostia (176, 180) through a single guiding catheter (130) which has distal exit ports (134, 136, 138) that are arranged to direct the perfusion catheters into the coronary ostia (176, 180). In each embodiment, the catheters (20) are equipped with an occlusion means (30, 50) at the distal end of the catheter (20) for closing the coronary ostia (176, 180), and isolating the coronary arteries from the systemic blood flow.

    Abstract translation: 提供导管系统用于从外周动脉进入部位（例如股动脉）进入腔内的冠状动脉口（176,180），并通过将心麻痹液直接输注到冠状动脉中诱导停搏。 在第一实施例中，导管系统是具有用于接合冠状动脉口（176,180）的多个远端分支（24,26,28）的单个灌注导管（20）的形式。 在第二实施例中，多个灌注导管（82,84）通过单个动脉插管（104）输送到冠状动脉口（176,180）。 在第三实施例中，多个灌注导管（112,114,116）通过单个引导导管（126）输送到冠状动脉口（176,180）。 在第四实施例中，多个导管（140,142,144）通过具有远端出口（134,136,138）的单个引导导管（130）输送到冠状动脉口（176,180），所述导向导管设置成引导 灌注导管进入冠状动脉口（176,180）。 在每个实施例中，导管（20）在导管（20）的远端配备有闭塞装置（30,50），用于封闭冠状动脉口（176,180），并将冠状动脉与全身血液隔离 流。

    ENDOVASCULAR CARDIAC VENTING CATHETER AND METHOD
    7.
    发明申请
    ENDOVASCULAR CARDIAC VENTING CATHETER AND METHOD 审中-公开
    内膜心脏透气导管和方法

    公开(公告)号：WO1996030073A1

    公开(公告)日：1996-10-03

    申请号：PCT/US1996003330

    申请日：1996-03-12

    Applicant: HEARTPORT, INC.

    Inventor： HEARTPORT, INC. ,  STEVENS, John, H. ,  KRIER, Jeffrey, W. ,  VALLEY, Kirsten, L. ,  EVARD, Philip, C.

    IPC: A61M29/00

    CPC classification number: A61M25/0041 ,  A61B2018/00232 ,  A61B2018/00261 ,  A61F2/2433 ,  A61F2/2436 ,  A61M1/3653 ,  A61M1/3659 ,  A61M25/007 ,  A61M25/0125 ,  A61M25/0662 ,  A61M25/10 ,  A61M29/02 ,  A61M2025/0004 ,  A61M2025/0078 ,  A61M2025/028 ,  A61M2025/1047 ,  A61M2025/1052 ,  A61M2025/1077 ,  A61M2210/125 ,  A61M2210/127

    Abstract: A venting catheter, system and method, are provided for withdrawing blood and other fluids from a patient's heart to facilitate decompressing the heart during cardioplegia arrest and cardiopulmonary bypass, without the need for a thoracotomy and without puncturing the aorta, pulmonary artery, or heart itself. The venting catheter (602) is configured to be introduced into a peripheral vein and intra-luminal advanced through the right side of the heart and into the pulmonary artery. The venting catheter includes a lumen (610) configured to withdraw blood at a rate of at least about 50 ml/min at a pressure of no less than about -350 mmHg. A flow directing means (615) is provided to facilitate guiding the catheter into the pulmonary artery by being carried by blood flow through the heart. The cardiac venting system may include, in addition to the cardiac venting catheter, a cardiopulmonary bypass system to maintain circulation of oxygenated blood, and means for arresting the patient's heart.

    Abstract translation: 提供排气导管，系统和方法，用于从患者的心脏中抽出血液和其它液体，以便在心跳停搏和心肺转流期间减压心脏，而不需要开胸术，而不需要穿刺主动脉，肺动脉或心脏本身 。 排气导管（602）构造成被引入外周静脉并且经腔内进入心脏的右侧并进入肺动脉。 排气导管包括构造成在不低于约-350mmHg的压力下以至少约50ml / min的速率抽出血液的内腔（610）。 提供流动引导装置（615）以便于通过被血液流过心脏而携带导管进入肺动脉。 除了心脏通气导管之外，心脏通气系统可以包括维持氧合血液循环的心肺旁路系统，以及用于阻止患者心脏的装置。

    SYSTEM AND METHODS FOR PERFORMING ENDOVASCULAR PROCEDURES
    9.
    发明申请
    SYSTEM AND METHODS FOR PERFORMING ENDOVASCULAR PROCEDURES 审中-公开
    用于执行内膜手术的系统和方法

    公开(公告)号：WO1996030072A1

    公开(公告)日：1996-10-03

    申请号：PCT/US1996003266

    申请日：1996-03-11

    Applicant: HEARTPORT, INC.

    Inventor： HEARTPORT, INC. ,  STEVENS, John, H. ,  PETERS, William, S. ,  STERMAN, Wesley, D. ,  GIFFORD, Hansen, S., III

    IPC: A61M29/00

    CPC classification number: A61M25/1011 ,  A61M25/0041 ,  A61M25/0152 ,  A61M2025/0161

    Abstract: This invention is a system for inducing cardio-plegia arrest and performing an endovascular procedure within the heart or blood vessels of a patient. An endo-aortic partitioning catheter (10) has an inflatable balloon (11) which occludes the ascending aorta (12) when inflated. Cardio-plegia fluid may be infused through a lumen of the endo-aortic partitioning catheter (39) to stop the heart while the patient's circulatory system is supported on cardiopulmonary bypass. One or more endovascular devices (500) are introduced through an internal lumen (40) of the endo-aortic partitioning catheter (30) to perform a diagnostic or therapeutic endovascular procedure within the heart or blood vessels of the patient. Surgical procedures such as coronary artery bypass surgery or heart valve replacement may be performed in conjunction with the endovascular procedure while the heart is stopped. Embodiments of the system are described for performing, e.g., fiberoptic angioscopy of structures within the heart and its blood vessels, and valvuloplasty for correction of valvular stenosis.

    Abstract translation: 本发明是一种用于诱导心脏 - 瘫痪并在患者的心脏或血管内进行血管内手术的系统。 内主动脉分隔导管（10）具有充气气囊（11），其在膨胀时封闭升主动脉（12）。 可以通过内主动脉分隔导管（39）的内腔输注心脏 - 小便液，以便在患者的循环系统被支持在体外循环时停止心脏。 一个或多个血管内装置（500）通过内主动脉分支导管（30）的内​​腔（40）引入，以在患者的心脏或血管内执行诊断或治疗性血管内手术。 外科手术如冠状动脉旁路手术或心脏瓣膜置换可以在心脏停止时与血管内手术一起进行。 描述了该系统的实施例，用于执行例如在心脏及其血管内的结构的光纤血管镜检查和用于矫正瓣膜狭窄的瓣膜成形术。

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