公开(公告)号：WO2007077961A3

公开(公告)日：2007-07-12

申请号：PCT/JP2006/326367

申请日：2006-12-27

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED ,  FUKUMOTO, Shoji ,  MATSUNAGA, Nobuyuki ,  OHRA, Taiichi ,  OHYABU, Norio ,  HASUI, Tomoaki ,  MOTOYAJI, Takashi ,  SIEDEM, Christopher, Stephen ,  TANG, Tony, Pisal ,  DEMEESE, Lisa, A. ,  GAUTHIER, Cassandra

Inventor： FUKUMOTO, Shoji ,  MATSUNAGA, Nobuyuki ,  OHRA, Taiichi ,  OHYABU, Norio ,  HASUI, Tomoaki ,  MOTOYAJI, Takashi ,  SIEDEM, Christopher, Stephen ,  TANG, Tony, Pisal ,  DEMEESE, Lisa, A. ,  GAUTHIER, Cassandra

IPC: C07D403/04 ,  C07D413/04 ,  C07D413/14 ,  C07D417/04 ,  C07D417/14 ,  C07D471/04 ,  C07D495/04 ,  C07D498/04 ,  C07D513/04 ,  A61K31/423 ,  A61K31/538 ,  A61K31/542 ,  A61P9/04 ,  A61P9/12

Abstract: The present invention relates to wherein each symbol is as defined in the specification. The compound has a superior mineral corticoidreceptorantagonistic action and is useful as an agent for the prophylaxis or treatment of hypertension, cardiac failure and the like, a compound having a fused heterocycle, or a prodrug thereof, or a salt thereof; and an agent for the prophylaxis or treatment of hypertension, cardiac failure and the like.

公开(公告)号：WO2012137982A3

公开(公告)日：2012-10-11

申请号：PCT/JP2012/059949

申请日：2012-04-05

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED ,  FUKUMOTO, Shoji ,  UJIKAWA, Osamu ,  MORIMOTO, Shinji ,  ASANO, Yasutomi ,  MIKAMI, Satoshi ,  TOKUNAGA, Norihito ,  KORI, Masakuni ,  IMAEDA, Toshihiro ,  FUKUDA, Koichiro ,  NAKAMURA, Shinji ,  IWANAGA, Kouichi

Inventor： FUKUMOTO, Shoji ,  UJIKAWA, Osamu ,  MORIMOTO, Shinji ,  ASANO, Yasutomi ,  MIKAMI, Satoshi ,  TOKUNAGA, Norihito ,  KORI, Masakuni ,  IMAEDA, Toshihiro ,  FUKUDA, Koichiro ,  NAKAMURA, Shinji ,  IWANAGA, Kouichi

IPC: C07C311/07 ,  C07C311/09 ,  C07C311/14 ,  C07C317/28 ,  C07C323/26 ,  C07D211/98 ,  C07D309/14 ,  C07D335/02 ,  A61P25/28 ,  A61P25/18 ,  A61P25/22 ,  A61P25/24 ,  A61K31/18

Abstract: Provided is a compound having an AMPA receptor function enhancing action, and useful as a prophylactic or therapeutic drug for depression, Alzheimer's disease, schizophrenia, attention deficit hyperactivity disorder (ADHD) and the like. A compound represented by the formula (I): wherein each symbol is as defined in the present specification, or a salt thereof.

公开(公告)号：WO2016002968A1

公开(公告)日：2016-01-07

申请号：PCT/JP2015/069370

申请日：2015-06-30

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Inventor： YAMAMOTO, Satoshi ,  SHIRAI, Junya ,  ODA, Tsuneo ,  KONO, Mitsunori ,  OCHIDA, Atsuko ,  IMADA, Takashi ,  TOKUHARA, Hidekazu ,  TOMATA, Yoshihide ,  ISHII, Naoki ,  TAWADA, Michiko ,  FUKASE, Yoshiyuki ,  YUKAWA, Tomoya ,  FUKUMOTO, Shoji

IPC: C07D217/14 ,  A61K31/4375 ,  A61K31/472 ,  A61K31/4741 ,  C07D471/04 ,  C07D491/14 ,  A61P11/06 ,  A61P17/06 ,  A61P19/02 ,  A61P43/00

CPC classification number: C07D217/26 ,  A61K31/4375 ,  A61K31/472 ,  A61K31/4741 ,  C07D217/14 ,  C07D471/04 ,  C07D491/048 ,  C07D491/056 ,  C07D491/14 ,  C07F7/0812

Abstract: Provided are heterocyclic compounds having a RORγt inhibitory action represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof.

Abstract translation: 提供具有由式（I）表示的RORγt抑制作用的杂环化合物：其中每个符号如说明书中所定义，或其盐。

公开(公告)号：WO2012137982A9

公开(公告)日：2012-10-11

申请号：PCT/JP2012/059949

申请日：2012-04-05

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED ,  FUKUMOTO, Shoji ,  UJIKAWA, Osamu ,  MORIMOTO, Shinji ,  ASANO, Yasutomi ,  MIKAMI, Satoshi ,  TOKUNAGA, Norihito ,  KORI, Masakuni ,  IMAEDA, Toshihiro ,  FUKUDA, Koichiro ,  NAKAMURA, Shinji ,  IWANAGA, Kouichi

Inventor： FUKUMOTO, Shoji ,  UJIKAWA, Osamu ,  MORIMOTO, Shinji ,  ASANO, Yasutomi ,  MIKAMI, Satoshi ,  TOKUNAGA, Norihito ,  KORI, Masakuni ,  IMAEDA, Toshihiro ,  FUKUDA, Koichiro ,  NAKAMURA, Shinji ,  IWANAGA, Kouichi

IPC: C07C311/07

Abstract: Provided is a compound having an AMPA receptor function enhancing action, and useful as a prophylactic or therapeutic drug for depression, Alzheimer's disease, schizophrenia, attention deficit hyperactivity disorder (ADHD) and the like. A compound represented by the formula (I): wherein each symbol is as defined in the present specification, or a salt thereof.

公开(公告)号：WO2012137982A2

公开(公告)日：2012-10-11

申请号：PCT/JP2012/059949

申请日：2012-04-05

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED ,  FUKUMOTO, Shoji ,  UJIKAWA, Osamu ,  MORIMOTO, Shinji ,  ASANO, Yasutomi ,  MIKAMI, Satoshi ,  TOKUNAGA, Norihito ,  KORI, Masakuni ,  IMAEDA, Toshihiro ,  FUKUDA, Koichiro ,  NAKAMURA, Shinji ,  IWANAGA, Kouichi

Inventor： FUKUMOTO, Shoji ,  UJIKAWA, Osamu ,  MORIMOTO, Shinji ,  ASANO, Yasutomi ,  MIKAMI, Satoshi ,  TOKUNAGA, Norihito ,  KORI, Masakuni ,  IMAEDA, Toshihiro ,  FUKUDA, Koichiro ,  NAKAMURA, Shinji ,  IWANAGA, Kouichi

IPC: C07C311/07

CPC classification number: C07C311/07 ,  C07C311/09 ,  C07C311/14 ,  C07C317/28 ,  C07C323/26 ,  C07C2601/02 ,  C07C2601/08 ,  C07C2601/14 ,  C07C2603/74 ,  C07D207/27 ,  C07D207/273 ,  C07D209/04 ,  C07D211/56 ,  C07D211/58 ,  C07D211/76 ,  C07D213/61 ,  C07D213/64 ,  C07D213/85 ,  C07D231/12 ,  C07D231/14 ,  C07D233/56 ,  C07D233/68 ,  C07D237/04 ,  C07D239/28 ,  C07D261/08 ,  C07D263/32 ,  C07D277/24 ,  C07D277/32 ,  C07D277/62 ,  C07D295/092 ,  C07D295/192 ,  C07D305/06 ,  C07D307/22 ,  C07D309/06 ,  C07D309/14 ,  C07D333/16 ,  C07D401/04 ,  C07D401/12 ,  C07D405/12 ,  C07D405/14 ,  C07D409/12 ,  C07D413/12 ,  C07D417/12 ,  C07D493/08

Abstract: Provided is a compound having an AMPA receptor function enhancing action, and useful as a prophylactic or therapeutic drug for depression, Alzheimer's disease, schizophrenia, attention deficit hyperactivity disorder (ADHD) and the like. A compound represented by the formula (I): wherein each symbol is as defined in the present specification, or a salt thereof.

Abstract translation: 提供具有AMPA受体功能增强作用的化合物，可用作抑郁症，阿尔茨海默氏病，精神分裂症，注意力缺陷多动障碍（ADHD）等的预防或治疗药物。 由式（I）表示的化合物或其盐，其中每个符号如本说明书中所定义。