NANOTHIN POLYMER FILMS WITH SELECTIVE PORES AND METHOD OF USE THEREOF
    1.
    发明申请
    NANOTHIN POLYMER FILMS WITH SELECTIVE PORES AND METHOD OF USE THEREOF 审中-公开
    具有选择性的纳米胶聚合物薄膜及其使用方法

    公开(公告)号:WO2009018508A1

    公开(公告)日:2009-02-05

    申请号:PCT/US2008/071884

    申请日:2008-08-01

    Abstract: A method of preparing nanothin polymer films having uniform and selectively sized pores utilizing pore forming templates. Lipids and pore forming templates are dissolved into a first solution. The solvent is removed thereby creating a lipid bilayer with pore forming templates dispersed throughout. The bilayer is hydrated and monomers and crosslinkers are added to create a second solution. A nanothin film with pore forming templates is created through polymerization of said second solution. The pore forming templates are dissolved into a third solution by addition of a chemical in which the pore forming template is soluble, but the lipid bilayer is insoluble. This third solution is separated from the mixture leaving a nanothin polymer film with pores of a uniform thickness and surface area. In summary, the guided assembly method presented here suggests a new general strategy for the fabrication of nanothin materials with controlled permeability, which provides improvements over the currently existing technology.

    Abstract translation: 使用孔形成模板制备具有均匀且选择性尺寸的孔的纳米级聚合物膜的方法。 将脂质和成孔模板溶解在第一溶液中。 除去溶剂,从而产生脂质双层,其中分布有成孔模板。 双层水合,加入单体和交联剂以产生第二溶液。 通过所述第二溶液的聚合产生具有孔形成模板的纳米薄膜。 孔形成模板通过添加其中成孔模板可溶的化学物质溶解到第三溶液中,但脂双层是不溶的。 将该第三溶液与混合物分离,留下具有均匀厚度和表面积的孔的纳米聚合物膜。 总而言之,这里介绍的引导装配方法提出了一种制备具有可控渗透率的纳米材料的新的总体策略,这提供了对现有技术的改进。

    PROCEDE DE PREPARATION D'UN COPOLYMERE AMPHIPHILE DIBLOC OU TRIBLOC COMPRENANT UN BLOC HYDROPHILE ET UN OU DEUX BLOCS HYDROPHOBES, PROCEDE DE PREPARATION D'UN MATERIAU ORGANIQUE MESOPOREUX UTILISANT CE COPOLYMERE, ET MATERIAU AINSI PREPARE
    2.
    发明申请
    PROCEDE DE PREPARATION D'UN COPOLYMERE AMPHIPHILE DIBLOC OU TRIBLOC COMPRENANT UN BLOC HYDROPHILE ET UN OU DEUX BLOCS HYDROPHOBES, PROCEDE DE PREPARATION D'UN MATERIAU ORGANIQUE MESOPOREUX UTILISANT CE COPOLYMERE, ET MATERIAU AINSI PREPARE 审中-公开
    制备具有氢键和一个或两个氢键的嵌段共聚物的方法,使用该共聚物制备有机异质材料的方法以及制备的材料

    公开(公告)号:WO2008129213A1

    公开(公告)日:2008-10-30

    申请号:PCT/FR2008/050452

    申请日:2008-03-14

    Abstract: L' invention a trait à un procédé de préparation d'un copolymère dibloc comprenant un bloc hydrophile (B) et un bloc hydrophobe (A), ou d'un copolymère tribloc comprenant un bloc hydrophile (B), un bloc hydrophobe (A) et un second bloc hydrophobe (A' ), ledit procédé comprenant les étapes suivantes : a) une étape d'addition 1,2 sur un groupe terminal éthylénique, ou deux groupes terminaux éthyléniques, d'un polymère hydrophile, d'une alcoxyamine répondant à la formule (I) suivante : dans laquelle : * R 1 et R 3 , identiques ou différents, représentent un groupe alkyle, linéaire ou ramifié, ayant un nombre d'atomes de carbone allant de 1 à 3; * R 2 représente un atome d'hydrogène, un métal alcalin, tel que Li, Na, K, un ion ammonium tel que NH 4 +, NBu 4 +, NHBu 3 +, un groupe alkyle, linéaire ou ramifié, ayant un nombre d'atomes de carbone allant de 1 à 8, un groupe phényle; b) une étape de mise en contact avec le milieu issu de l'étape a) d'un ou plusieurs monomères précurseurs d'un bloc hydrophobe pendant un temps suffisant pour obtenir le copolymère dibloc bloc hydrophile (B) - b -bloc hydrophobe (A) dans le cas où l'étape d'addition a) s'est produite sur un seul groupe terminal éthylénique du polymère hydrophile; ou pour obtenir le copolymère tribloc bloc hydrophile (A) -b-bloc hydrophile (B) -b-second bloc hydrophobe (A' ) dans le cas où l'étape d'addition a) s'est produite sur deux groupes terminaux éthyléniques du polymère hydrophile. Utilisation des copolymères obtenus en tant qu'agents structurants de matériaux mésoporeux, tels que la silice présentant des tailles de pores supérieures à 15 nm.

    Abstract translation: 本发明涉及制备包含亲水嵌段(B)和疏水嵌段(A)的二嵌段共聚物或具有亲水嵌段(B),疏水嵌段(A)和第二嵌段 疏水嵌段(A'),所述方法包括以下步骤:a)在具有下式(I)的烷氧基​​胺的亲水性聚合物的乙烯端基或两个末端亚乙基端基上的加成步骤1,2, :其中:R 1,R 3和R 3,相同或不同,代表具有1-3个碳原子数的直链或支链烷基; * R 2表示氢原子,碱金属如Li,Na,K,铵离子如NH 4 +,NBu 4, 具有1至8个碳原子的直链或支链的烷基,苯基, b)与疏水嵌段的一种或多种前体单体的步骤a)的介质接触足够的时间以获得亲水性二嵌段共聚物(B)-b嵌段疏水性(A)的步骤,在这种情况下 添加步骤a)仅在亲水性聚合物的末端亚乙基之一上发生; 或在亲水性聚合物的两个末端亚乙基上发生加成反应a)的情况下获得亲水性三嵌段共聚物(A)-b-嵌段亲水性(B)-b-第二嵌段疏水性(A')。 使用由此获得的共聚物作为介孔材料的结构剂,例如孔径大于15nm的二氧化硅。

    MICROCONCENTRATOR/MICROFILTER
    3.
    发明申请
    MICROCONCENTRATOR/MICROFILTER 审中-公开
    微量浓缩/ MICROFILTER

    公开(公告)号:WO2006079007A3

    公开(公告)日:2006-11-16

    申请号:PCT/US2006002229

    申请日:2006-01-20

    Abstract: The present invention includes a microfluidic filter and concentrator that can separate a filtrate from a fluid containing components, e.g. a suspension of particles, to be removed from the fluid at least to some extent. The filter may employ principals of tangential flow filtration, also known as cross-flow filtration. In one aspect, a microfluidic filter described herein includes at least a first, main channel and one or more secondary, filtering channels that connect to the main channel. Filtration occurs when a fluid portion of a sample that is flowed through the main channel enters one or more of the filtering channels and at least some of the components in the sample do not enter or do not flow through the secondary, filtering channels. The secondary channels may be dimensioned to inhibit flow of components through them, and/or a porous material such as a layer may be positioned to inhibit flow of components through the secondary channels.

    Abstract translation: 本发明包括微流体过滤器和浓缩器,其可以将滤液与含有组分的流体分离,例如, 至少在一定程度上从流体中除去颗粒的悬浮液。 过滤器可以采用切向流过滤的原理,也称为交叉流过滤。 在一个方面,本文描述的微流控滤波器至少包括连接到主通道的第一主通道和一个或多个次级滤波通道。 当流过主通道的样品的流体部分进入一个或多个过滤通道并且样品中的至少一些组分不进入或不流过次级过滤通道时,发生过滤。 次级通道的尺寸可以限制通过它们的部件的流动,和/或诸如层的多孔材料可以被定位成阻止部件通过次级通道的流动。

    CRYSTALLINE MEMBRANES
    4.
    发明申请
    CRYSTALLINE MEMBRANES 审中-公开
    晶体膜

    公开(公告)号:WO2004080889A3

    公开(公告)日:2005-09-29

    申请号:PCT/US2004006950

    申请日:2004-03-05

    Abstract: In certain aspects, the invention features methods for forming crystalline membranes (20) (e.g., a membrane of a framework material, such as a zeolite) by inducing secondary growth in a layer of oriented seed crystals (32). The rate of growth of the seed crystals in the plane of the substrate (30) is controlled to be comparable to the rate of growth out of the plane. As a result, a crystalline membrane can form a substantially continuous layer including grains (35) of uniform crystallographic orientation that extend through the depth of the layer.

    Abstract translation: 在某些方面,本发明的特征在于通过在定向晶种层(32)中诱导二次生长来形成结晶膜(20)(例如框架材料的膜,例如沸石)的方法。 将基底(30)的平面中的晶种的生长速率控制为与平面的生长速度相当。 结果,结晶膜可以形成基本上连续的层,包括延伸穿过层的深度的均匀晶体取向的晶粒(35)。

    MULTI-SIDED IMMERSION FORMATION OF COMPOSITE STRUCTURES AND METHOD
    5.
    发明申请
    MULTI-SIDED IMMERSION FORMATION OF COMPOSITE STRUCTURES AND METHOD 审中-公开
    复合结构和方法的多边倾斜形成

    公开(公告)号:WO2004037850A3

    公开(公告)日:2005-03-10

    申请号:PCT/US0333285

    申请日:2003-10-20

    Applicant: MILLIPORE CORP

    Abstract: Sample preparation device and method for desalting and concentrating samples prior to further analysis such as by MALDI TOF and/or electro-spray ionization (ESI) mass spectrometry. The device in accordance with an embodiment of the present invention contains a three dimensional structure preferably comprising a plurality of sorptive particles e, it apped in a porous polymer matrix so as to form a device capable of carrying out solid phase extraction. The device is manufactured by introducing casting solution containing polymer and optionally particles into a housing, and subsequently exposing the device to a quench bath for a time sufficient to allow for solvent exchange and precipitation to form the composite structure in the housing. The present invention is also directed towards a method of sample preparation using the device of the present invention.

    Abstract translation: 在进一步分析之前,例如通过MALDI TOF和/或电喷雾离子化(ESI)质谱法进行脱盐和浓缩样品的样品制备装置和方法。 根据本发明的实施方案的装置包含优选包含多个吸附颗粒e的三维结构,其附着在多孔聚合物基质中以形成能够进行固相萃取的装置。 该装置通过将含有聚合物和任选的颗粒的浇铸溶液引入壳体而制造,并且随后将该装置暴露于淬火浴中足以允许溶剂交换和沉淀以在壳体中形成复合结构的时间。 本发明还涉及使用本发明的装置的样品制备方法。

    MULTI-SIDED IMMERSION FORMATION OF COMPOSITE STRUCTURES AND METHOD
    6.
    发明申请
    MULTI-SIDED IMMERSION FORMATION OF COMPOSITE STRUCTURES AND METHOD 审中-公开
    复合结构和方法的多边倾斜形成

    公开(公告)号:WO2004037850A2

    公开(公告)日:2004-05-06

    申请号:PCT/US2003/033285

    申请日:2003-10-20

    IPC: C07K

    Abstract: Sample preparation device and method for desalting and concentrating samples prior to further analysis such as by MALDI TOF and/or electro-spray ionization (ESI) mass spectrometry. The device in accordance with an embodiment of the present invention contains a three dimensional structure preferably comprising a plurality of sorptive particles e, it apped in a porous polymer matrix so as to form a device capable of carrying out solid phase extraction. The device is manufactured by introducing casting solution containing polymer and optionally particles into a housing, and subsequently exposing the device to a quench bath for a time sufficient to allow for solvent exchange and precipitation to form the composite structure in the housing. The present invention is also directed towards a method of sample preparation using the device of the present invention.

    Abstract translation: 在进一步分析之前,例如通过MALDI TOF和/或电喷雾离子化(ESI)质谱法进行脱盐和浓缩样品的样品制备装置和方法。 根据本发明的实施方案的装置包含优选包含多个吸附颗粒e的三维结构,其附着在多孔聚合物基质中以形成能够进行固相萃取的装置。 该装置通过将含有聚合物和任选的颗粒的浇铸溶液引入壳体而制造,并且随后将该装置暴露于淬火浴中足以允许溶剂交换和沉淀以在壳体中形成复合结构的时间。 本发明还涉及使用本发明的装置的样品制备方法。

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