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    BIO-BASED DISPERSANTS
    3.
    发明申请
    BIO-BASED DISPERSANTS 审中-公开
    基于生物的分散剂

    公开(公告)号：WO2014145972A2

    公开(公告)日：2014-09-18

    申请号：PCT/US2014030835

    申请日：2014-03-17

    申请人： ETHOX CHEMICALS LLC

    发明人： TANNER JAMES T

    IPC分类号： C11C3/00 ,  C09D7/45

    CPC分类号： C07D219/08 ,  C07C219/08 ,  C07C219/12 ,  C07C2601/16 ,  C08K5/175

    摘要： The invention provides a novel bio-based dispersant comprising the reaction product of a natural triglyceridic oil, fatty acid oil or fatty acid oil derivative wherein said natural triglyceridic oil, fatty acid oil, or fatty acid oil derivative containing greater than about 80 percent of unsaturated or conjugated unsaturated fatty acids with a substrate capable of undergoing an ene or Diels Alder reaction to form an adduct that is further esterified and/or neutralized with an alkanolamine or alkoxylated alkanolamine.

    摘要翻译： 本发明提供了一种新型的基于生物的分散剂，其包含天然三甘油硅油，脂肪酸油或脂肪酸油衍生物的反应产物，其中所述天然三甘油硅油，脂肪酸油或脂肪酸油衍生物含有大于约80％的不饱和 或共轭不饱和脂肪酸与能够经历烯或Diels Alder反应的底物反应以形成加成物，所述加合物进一步用链烷醇胺或烷氧基化链烷醇胺酯化和/或中和。

    ALPHA-HYDROXYKETONES
    4.
    发明申请
    ALPHA-HYDROXYKETONES 审中-公开
    α-羟基

    公开(公告)号：WO2008122504A1

    公开(公告)日：2008-10-16

    申请号：PCT/EP2008/053458

    申请日：2008-03-25

    申请人： CIBA HOLDING INC. ,  DIETLIKER, Kurt ,  MURER, Peter ,  HÜSLER, Rinaldo ,  JUNG, Tunja

    发明人： DIETLIKER, Kurt ,  MURER, Peter ,  HÜSLER, Rinaldo ,  JUNG, Tunja

    IPC分类号： C07D211/32 ,  C07D241/04 ,  C07C49/543 ,  C07C62/30 ,  C07C229/46 ,  C07F7/08

    CPC分类号： C07D211/32 ,  C07C49/83 ,  C07C49/835 ,  C07C49/84 ,  C07C62/38 ,  C07C69/757 ,  C07C219/12 ,  C07C235/82 ,  C07C2601/14 ,  C07D295/185 ,  C07D305/12 ,  C07F7/0836 ,  C07F7/0854 ,  C07F7/1868 ,  G03F7/004 ,  G03F7/38 ,  G03F7/40

    摘要： Compounds of theFormula (I) wherein x is an integer from 1-4; p is an integer from 1-3; q is an integer from 0-3; Ar is phenyl, naphthyl, anthryl or phenanthryl each of which optionally is substituted by one or more Cl, CN, OR 5 , C 3 -C 5 alkenyl or C 1 -C 6 alkyl which optionally is substituted by one or more OR 6 , COOR or halogen; R 1 ifx is 1, is OR 7 , O- X + , NR 8 R 9 , C 1 -C 20 alkyl optionally substituted by one or more COOR 10 , or is C 2 -C 20 alkyl interrupted by one ore more O, or is C 2 -C 5 alkenyl or phenyl-C 1 -C 4 alkyl; R 1 ifx is 2, is for example C 1 -C 20 alkylene; R 1 ifx is 3, is for example a tri- valent radical; R 1 if x is 4, is for example a tetravalent radical; R 2 and R 3 are hydrogen or C 1 - C 8 alkyl, or R 2 and R 3 together are O, C 1 -C 3 alkylene or CH=CH; R 4 is C 1 -C 4 alkyl; R 5 , R 6 , R 7 , R 8 , R 9 and R 10 are for example hydrogen or C 1 -C 4 alkyl; and X is a x-valent cationic counter ion; are in particular suitable as photoinitiators forthe curing with UV-A light (320-450 nm).

    摘要翻译： 式（I）的化合物，其中x是1-4的整数; p是1-3的整数; q是0-3的整数; Ar是苯基，萘基，蒽基或菲基，其各自任选被一个或多个Cl，CN，OR 5，C 3 -C 5 - 任选被一个或多个OR 6，COOR或卤素取代的亚烷基或C 1 -C 6 -C 6烷基; R 1 x 1是1，是OR 7，O-X +，NR 8 R 9 或任选被一个或多个COOR 10取代的C 1 -C 20烷基或C 2 -C 20烷基， 被一个或多个O取代的C 1 -C 20烷基或C 2 -C 5 - 烯基或苯基-C 1 -C 4 烷基; R 1，如果x为2，则为例如C 1 -C 20亚烷基; R 1是3，例如是3价基团; 如果x为4，则R 1为例如四价基团; R 2和R 3是氢或C 1 -C 8烷基，或R 2， R 3和R 3一起是O，C 1 -C 3亚烷基或CH = CH; R 4是C 1 -C 4烷基; R 4是C 1 -C 4烷基; R 5，R 6，R 7，R 8，R 9和R 9和 R 10是例如氢或C 1 -C 4烷基; X为x-阳离子抗衡离子; 特别适用于用UV-A光（320-450nm）固化的光引发剂。

    ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION
    7.
    发明申请
    ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION 审中-公开
    乙酰胆碱羧酸酯，其使用，药物组合物和制剂

    公开(公告)号：WO1998004517A1

    公开(公告)日：1998-02-05

    申请号：PCT/SE1997001310

    申请日：1997-07-23

    申请人： PHARMACIA & UPJOHN AB ,  ÅKERBLOM, Eva ,  HARALDSSON, Martin ,  JOHANSSON, Rolf ,  BEIERLEIN, Katarina ,  SJÖBERG, Birger ,  RINGBERG, Erik ,  WEINZ, Birgitta

    发明人： PHARMACIA & UPJOHN AB

    IPC分类号： C07C219/12

    CPC分类号： C07D409/12 ,  C07C219/12 ,  C07C2601/04 ,  C07D207/12 ,  C07D211/22 ,  C07D317/72 ,  C07D333/24 ,  C07D451/06 ,  C07D453/02 ,  C07D487/08

    摘要： The invention relates to the use of compounds of general Formula (IA) wherein: A is an optionally substituted cycloalkane ring having 3 to 6 carbon atoms and attached at a single ring carbon atom thereof; Ar is phenyl or heteroaryl having 5 or 6 ring members, R1 and R2 independently are hydrogen, lower alkyl, lower alkoxy, halo, hydroxy, trifluoromethyl, nitro or amino, or R1 and R2 together form lower alkylenedioxy or optionally substituted benzo; and R3 is (i) -(CH2)nNR10, R11, in which n is 2 or 3 and R10 and R11 each are lower alkyl or R10 and R11 together with the nitrogen atom form a saturated azacyclic or azabicyclic ring system; or (ii) -(CH2)m-Q, in which m is 0 or 1 and Q is the residue of a saturated azacyclic or azabicyclic ring system coupled via a carbon atom thereof, or a pharmacologically acceptable salt thereof, for treatment of urinary incontinence or irritable bowel syndrome. The invention also relates to novel compounds encompassed by Formula (IA), pharmaceutical compositions thereof and preparation of the compounds.

    摘要翻译： 本发明涉及通式（IA）化合物的用途，其中：A为任选取代的具有3至6个碳原子的环烷烃环，并在其单环碳原子上连接; Ar是具有5或6个环成员的苯基或杂芳基，R 1和R 2独立地是氢，低级烷基，低级烷氧基，卤素，羟基，三氟甲基，硝基或氨基，或者R 1和R 2一起形成低级亚烷基二氧基或任选取代的苯并; 并且R 3为（i） - （CH 2）n NR 10，R 11，其中n为2或3，R 10和R 11各自为低级烷基或R 10，R 11与氮原子一起形成饱和的氮杂环或氮杂双环系; 或（ii） - （CH 2）m Q，其中m为0或1，Q为通过其碳原子或其药理学上可接受的盐偶联的用于治疗尿失禁的饱和氮杂环或氮杂双环体系的残基， 过敏性肠综合征。 本发明还涉及由式（IA）包括的新化合物，其药物组合物和化合物的制备。

    NOVEL ANILINIUM SALT COMPOUND AND POLYMERIZATION INITIATOR
    8.
    发明申请
    NOVEL ANILINIUM SALT COMPOUND AND POLYMERIZATION INITIATOR 审中-公开
    新型盐酸盐化合物和聚合引发剂

    公开(公告)号：WO1994014754A1

    公开(公告)日：1994-07-07

    申请号：PCT/JP1993001876

    申请日：1993-12-24

    申请人： NIPPON SODA CO., LTD. ,  TAKAHASHI, Eiji; ,  MURAMOTO, Hiroo;

    发明人： NIPPON SODA CO., LTD.

    IPC分类号： C07C211/64

    CPC分类号： C07C229/18 ,  C07C211/64 ,  C07C215/16 ,  C07C217/28 ,  C07C219/06 ,  C07C219/12 ,  C07C225/06 ,  C07C255/24 ,  C07C2601/14

    摘要： An anilinium salt compound represented by general formula (I) and a cationic polymerization initiator containing at least one said compound, wherein R1 represents hydrogen, alkyl, etc.; R2 represents alkyl, etc.; R3 represents alkyl substituted on the alpha -, beta - or UPSILON -carbon atom with respect to the nitrogen atom; R4 and R5 represents each hydrogen, halogen etc.; and X represents a non-nucleophilic counter anion residue. When the invention compound is used as a polymerization initiator, a cationically polymerizable compound can readily be polymerized under a mild temperature condition of near ordinary temperature up to 100 DEG C. When used as a curing catalyst, it can readily provide a cured article having high cross-linking density and glass transition point and excellent properties in the comparatively low temperature range of ordinary temperature to near 170 DEG C.

    摘要翻译： 由通式（I）表示的苯胺鎓盐化合物和含有至少一种所述化合物的阳离子聚合引发剂，其中R1表示氢，烷基等; R2代表烷基等; R3表示相对于氮原子在α，β或UPSILON-碳原子上取代的烷基; R4和R5代表每个氢，卤素等; X表示非亲核抗衡阴离子残基。 当本发明化合物用作聚合引发剂时，阳离子聚合性化合物可以在接近常温至100℃的温和条件下容易地聚合。当用作固化催化剂时，可以容易地提供具有高 交联密度和玻璃化转变点，在常温至170℃的较低温度范围内具有优异的性能。

    3-AMINO-PROPOXYPHENYL DERIVATIVES (I)
    10.
    发明申请
    3-AMINO-PROPOXYPHENYL DERIVATIVES (I) 审中-公开
    3-氨基 - 丙氧基衍生物（I）

    公开(公告)号：WO1997013744A1

    公开(公告)日：1997-04-17

    申请号：PCT/AU1996000638

    申请日：1996-10-10

    申请人： THE UNIVERSITY OF MELBOURNE ,  LOUIS, William, John ,  JACKMAN, Graham, Paul ,  IAKOVIDIS, Dimitrios ,  LOUIS, Simon, Nicholas, Stewart ,  DRUMMER, Olaf, Heino

    发明人： THE UNIVERSITY OF MELBOURNE

    IPC分类号： C07C217/34

    CPC分类号： A61K31/137 ,  A61K31/277 ,  C07C217/34 ,  C07C217/60 ,  C07C219/06 ,  C07C219/12 ,  C07C219/14 ,  C07C255/54 ,  C07C2601/02

    摘要： Compounds of formula (Ia) as potent, beta 1-specific beta blockers with a short duration of action in the systemic circulation, wherein R is 3',4'-dimethoxyphenyl, R is hydrogen, and R is selected from methyl, ethyl, propyl, isobutyl and isopropyl; or R is 3',4'-dimethoxyphenyl, R is selected from fluorine, chlorine and bromine, and R is selected from methyl, ethyl, propyl, isopropyl, isobutyl and cyclopropylmethyl; or R is 4'-methoxyphenoxy, R is selected from hydrogen, fluorine, chlorine and bromine, and R is selected from methyl, ethyl, propyl, isopropyl, isobutyl and cyclopropylmethyl; or R is 3',4'-dimethoxyphenyl, R is cyano, and R is cyclopropylmethyl; or R is 4'-methoxyphenoxy, R is cyano, and R is isobutyl; and physiologically acceptable hydrolysable derivatives thereof having the hydroxy group in the 2-position of the 3-aminopropoxy side chain in esterified form, in their racemic and optically active forms, and their pharmaceutically acceptable acid addition salts.

    摘要翻译： 式（Ia）化合物作为在全身循环中具有短暂作用持续时间的有效的β1-特异性β受体阻滞剂，其中R为3'，4'-二甲氧基苯基，R 1为氢，R 2为 选自甲基，乙基，丙基，异丁基和异丙基; 或R 3为3'，4'-二甲氧基苯基，R 1选自氟，氯和溴，R 2选自甲基，乙基，丙基，异丙基，异丁基和环丙基甲基; 或R是4'-甲氧基苯氧基，R 1选自氢，氟，氯和溴，R 2选自甲基，乙基，丙基，异丙基，异丁基和环丙基甲基; 或R 3为3'，4'-二甲氧基苯基，R 1为氰基，R 2为环丙基甲基; 或R是4'-甲氧基苯氧基，R 1是氰基，R 2是异丁基; 其在3-氨基丙氧基侧链的2-位具有羟基的生理上可接受的可水解的衍生物，其外消旋和旋光形式及其药学上可接受的酸加成盐。