摘要:
The invention relates to a measuring device and a method for determining mass and/or mechanical properties of a biological system. The biological system is attached to a micro-cantilever which is excited by an intensity-modulated light source. The mass is calculated from the change in resonance frequency of the micro-cantilever.
摘要:
An objective testing module includes a module base configured for coupling with an objective turret of a microscope. The objective testing module includes a mechanical testing assembly. The mechanical testing assembly is configured to mechanically test a sample at macro scale or less, and quantitatively determine one or more properties of the sample based on the mechanical testing. The mechanical testing assembly optionally includes a probe and one or more transducers coupled with the probe. The transducer measures one or more of force applied to a sample by the probe or displacement of the probe within the sample. In operation, an optical instrument locates a test location on a sample and the objective testing module mechanically tests at the test location with the mechanical testing assembly at a macro scale or less. The mechanical testing assembly further determines one or more properties of the sample according to the mechanical test.
摘要:
Está provisto de una horquilla resonante y una punta rectilínea fijada a una pata de la horquilla, una superficie de soporte de objetos a analizar y medios para sostener y desplazar a la horquilla, dispuestos de modo que la punta está inclinada con respecto a la superficie de soporte, siendo dicho ángulo tal que permite explorar con una punta rectilínea evitando a la vez que la horquilla entre en contacto con los objetos o el líquido donde dicho objeto podría estar sumergido, haciendo posible simultáneamente acceder visualmente a la posición del extremo de la punta rectilínea desde encima dicha superficie de soporte y que permite colocar una pluralidad de conjuntos de horquilla resonante/ punta, lo cual permite a su vez medir simultáneamente varios parámetros físicos de la superficie del objeto.
摘要:
Die Erfindung betrifft eine Vorrichtung und ein Verfahren zum sondenmikroskopischen Untersuchen einer Probe, insbesondere zum rastersondenmikroskopischen Untersuchen. Die Vorrichtung umfasst eine Sondemikroskopeinrichtung, welche eine Probenaufnahme zum Aufnehmen einer zu untersuchenden Probe, eine Messsonde und eine Verlagerungseinheit aufweist, die konfiguriert ist, für eine sondenmikroskopische Untersuchung der Probe die Probenaufnahme und die Messsonde relativ zueinander zu verlagern, und eine Kondensorbeleuchtung sowie ein der Kondensorbeleuchtung nachgelagertes optisches System, welches konfiguriert ist, von der Kondensorbeleuchtung in einen Kondensorlichtweg abgegebenes Kondensorlicht unter wenigstens teilweiser Aufrechterhaltung von Kondensorlichtparametern, mit denen das Kondensorlicht von der Kondensorbeleuchtung abgegeben wird, in den Bereich der Probenaufnahme für eine optische Mikroskopie der zu untersuchenden Probe abzubilden.
摘要:
Methods and systems for operating an apertureless microscope for observing one or more features to a molecular sensitivity on objects are described. More particularly, the method includes moving a tip of a probe coupled to a cantilever in a vicinity of a feature of a sample, which emits one or more photons at a detected rate relative to a background rate of the sample based upon the presence of the tip of the probe in the vicinity of the feature. The method modifies the detected rate of the feature of the sample, whereupon the modifying of the detected rate causes the feature of the sample to enhance relative to background rate of the feature.
摘要:
A scanning probe microscope (SPM) system is provided, which is removably attachable to an objective of an optical microscope comprising an objective mounting adaptor, with an SPM assembly attached thereto by means of an SPM mounting adaptor and an SPM assembly and cap. The objective mounting adaptor and SPM assembly each include an optically transmissive region through which an optical view of the sample can be obtained by the microscope objective.
摘要:
A LAB ON A CHIP Figure 1 shows the cross-sectional view of the microchip, which in this case is provided in the form of a silicon wafer. The microchip has an upper surface (2) and a lower surface (3). The upper surface (2) has at least one opening (4) which extends into the microchip and is filled with a dielectric such as silicon dioxide. In the bottom wall there is a channel (5) which is aligned with the opening (4) and provides an optical passage through the microchip.