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    ANTI-SEBUM SKIN CARE COSMETIC COMPOSITIONS CONTAINING BRANCHED ESTERS
    1.
    发明申请
    ANTI-SEBUM SKIN CARE COSMETIC COMPOSITIONS CONTAINING BRANCHED ESTERS 审中-公开
    抗黑色皮肤护理化妆品组合物

    公开(公告)号：WO00074642A1

    公开(公告)日：2000-12-14

    申请号：PCT/EP2000/004749

    申请日：2000-05-23

    IPC: A61K8/00 ,  A61K8/19 ,  A61K8/25 ,  A61K8/30 ,  A61K8/37 ,  A61K8/67 ,  A61Q19/00 ,  A61Q19/08 ,  A61K7/48

    CPC classification number: A61Q19/00 ,  A61K8/37 ,  A61K8/375 ,  A61Q19/08 ,  Y10S514/846 ,  Y10S514/873

    Abstract: The present invention provides cosmetic skin care methods and compositions containing methyl-branched esters. The compositions contain a branched chain ester RCOOR' wherein R is selected from the group consisting of CH3, phenyl, and CH3(CH2)4CH=CHCH2CH=CH(CH2); and R' is a methyl-branched hydrocarbon radical containing a total of at least 6 carbon atoms, provided that if R' contains more than 6 carbon atoms in total, the branched ester contains more than one methyl group. The compositions provide control of sebum secretion from sebocytes, improved oil control and improved skin feel, prevent shine and stickiness, while also providing anti-aging benefits which results in reduced appearance of wrinkles and aged skin, improved skin color, treatment of photoaged skin, improvement in skin's radiance and clarity and finish, and an overall healthy and youthful appearance of the skin.

    Abstract translation: 本发明提供了含有甲基支链酯的化妆品护肤方法和组合物。 该组合物含有支链酯RCOOR'，其中R选自CH 3，苯基和CH 3（CH 2）4 CH = CHCH 2 CH = CH（CH 2）; 并且R'是含有总共至少6个碳原子的甲基支链烃基，条件是如果R'总共含有多于6个碳原子，则支链酯含有多于一个甲基。 该组合物可以控制皮脂分泌从皮脂细胞，改善的油控制和改善的皮肤感觉，防止光泽和粘性，同时还提供抗衰老的益处，从而减少皱纹和老化皮肤的外观，改善皮肤颜色，治疗皮肤光泽， 改善皮肤的光亮度和清晰度，完成皮肤整体健康和年轻的外观。

    POLYMERIC DIFUNCTIONAL CATIONIC EMOLLIENTS AND CONDITIONERS FOR USE IN COSMETIC, PERSONAL CARE AND HOUSEHOLD PRODUCTS
    2.
    发明申请
    POLYMERIC DIFUNCTIONAL CATIONIC EMOLLIENTS AND CONDITIONERS FOR USE IN COSMETIC, PERSONAL CARE AND HOUSEHOLD PRODUCTS 审中-公开
    用于化妆品，个人护理和家居用品的聚合物功能性阳离子和调节剂

    公开(公告)号：WO99054027A1

    公开(公告)日：1999-10-28

    申请号：PCT/US1999/008143

    申请日：1999-04-14

    IPC: A61K8/41 ,  A61K8/42 ,  A61K8/85 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q9/02 ,  A61Q17/04 ,  A61Q19/00 ,  B01F17/00 ,  C11D3/20 ,  A61K7/00 ,  A61K7/06 ,  A61K7/15 ,  B01F17/16 ,  B01F17/30

    CPC classification number: B01F17/005 ,  A61K8/41 ,  A61K8/416 ,  A61K8/42 ,  A61K8/85 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q9/02 ,  A61Q15/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/10 ,  B01F17/0028 ,  Y10S514/873 ,  Y10S516/914 ,  Y10S516/917

    Abstract: The present invention also relates to chemical compositions comprising the neutralization product of at least one amine neutralization compound (preferably, a diamine) and a carboxylic acid (preferably, a dicarboxylic acid), said amine neutralization compound comprising about 1 % to about 100 % by weight (of the total amount of amine neutralization containing compound) of a first amine compound and 0 % to about 99 % by weight of a second amine compound different from said first amine compound, said first amine compound being a polyamine containing at least one tertiary amine group and at least one quaternary amine group, said tertiary amine group of said first amine reacting with said carboxylic acid group to produce a tertiary ammonium carboxylate salt, said second amine compound containing at least one primary, secondary or tertiary amine group with the proviso that when said second amine contains only primary and/or secondary amine groups, the amount of said second amine in said amine neutralization compound is no greater than about 20 % (preferably, no greater than about 10 %) by weight and said carboxylic acid comprises at least about 50 % by weight (more preferably at least about 75 % by weight, even more preferably about 90 % by weight and even more preferably about 100 % by weight of a polycarboxylic acid, more preferably a dicarboxylic acid.

    Abstract translation: 本发明还涉及包含至少一种胺中和化合物（优选二胺）和羧酸（优选二羧酸）的中和产物的化学组合物，所述胺中和化合物包含约1％至约100％的 第一胺化合物的重量（含胺中和的化合物的总量）和与所述第一胺化合物不同的0％至约99重量％的第二胺化合物，所述第一胺化合物是含有至少一个叔胺 胺基团和至少一个季胺基团，所述第一胺的所述叔胺基团与所述羧酸基团反应以产生叔羧酸铵盐，所述第二胺化合物含有至少一个伯，仲或叔胺基团，条件是 当所述第二胺仅含有伯和/或仲胺基团时，所述第二胺在所述氨基中的量 中和化合物不大于约20重量％（优选不大于约10重量％），并且所述羧酸包含至少约50重量％（更优选至少约75重量％，甚至更优选约90重量％ 重量％，甚至更优选约100重量％的多元羧酸，更优选二羧酸。

    CLEAR ANTIPERSPIRANT OR DEODORANT GEL COMPOSITION WITH VOLATILE LINEAR SILICONE TO REDUCE STAINING
    3.
    发明申请
    CLEAR ANTIPERSPIRANT OR DEODORANT GEL COMPOSITION WITH VOLATILE LINEAR SILICONE TO REDUCE STAINING 审中-公开
    用挥发性线性硅酮清除抗凝剂或去污剂组合物，减少污染

    公开(公告)号：WO1998032418A1

    公开(公告)日：1998-07-30

    申请号：PCT/US1997023272

    申请日：1997-12-16

    Applicant: THE GILLETTE COMPANY ,  KARASSIK, Nancy, M. ,  ANGELONE, Philip, P., Jr. ,  BOYLE, Patricia, Riley ,  DI DOMIZIO, Patricia ,  GALANTE, Cheryl, Weston ,  PATEL, Jay, C. ,  ROGERS, Patricia, A.

    Inventor： THE GILLETTE COMPANY

    IPC: A61K07/32

    CPC classification number: A61K8/894 ,  A61K8/042 ,  A61K8/06 ,  A61K8/064 ,  A61K8/585 ,  A61K8/891 ,  A61K2800/262 ,  A61K2800/52 ,  A61Q15/00 ,  Y10S514/873 ,  Y10S514/944

    Abstract: The present invention is directed to a clear antiperspirant or deodorant gel composition which exhibits reduced staining while retaining excellent aesthetic attributes and efficacy. The gel composition is a water-in-oil emulsion having a viscosity of about 50,000 to 250,000 cP, preferably about 100,000 to 200,000 cP. The water phase comprises about 75 to 90 % of the composition and contains a deodorant or antiperspirant effective amount (e.g. about 3 to 25 %) of an antiperspirant active dissolved therein. The oil phase comprises about 10 to 25 % of the composition and contains a silicone oil and a polyether substituted silicone emulsifying agent. The silicone oil comprises a mixture of a non-volatile silicone, preferably a non-volatile linear silicone, and a volatile linear silicone. It has been found that reducing the amount of non-volatile silicone in the known gel composition to a relatively low level (e.g. below about 5 %) and adding an amount of volatile linear silicone to the composition (e.g. above about 2 %, preferably above about 5 %) substantially improves the non-staining properties of the composition.

    Abstract translation: 本发明涉及一种清晰的止汗或除臭凝胶组合物，其在保留优异的美学特性和功效的同时显示减少的染色。 凝胶组合物是具有约50,000至250,000cP，优选约100,000至200,000cP的粘度的油包水乳液。 水相包含组合物的约75-90％，并含有溶解于其中的除臭剂或止汗剂有效量（例如约3至25％）的止汗活性剂。 油相包含约10至25％的组合物，并含有硅油和聚醚取代的硅氧烷乳化剂。 硅油包括非挥发性硅酮，优选非挥发性线性硅氧烷和挥发性线性硅氧烷的混合物。 已经发现，将已知凝胶组合物中的非挥发性硅氧烷的量减少到相对低的水平（例如低于约5％），并向组合物中加入一定量的挥发性线性硅氧烷（例如高于约2％，优选高于 约5％）基本上改善了组合物的非染色性能。

    SELF-EMULSIFYING AND/OR EMOLLIENT AGENTS
    5.
    发明申请
    SELF-EMULSIFYING AND/OR EMOLLIENT AGENTS 审中-公开
    自我激励和/或外部代理

    公开(公告)号：WO1996004987A1

    公开(公告)日：1996-02-22

    申请号：PCT/US1995009688

    申请日：1995-08-08

    Applicant: HENKEL CORPORATION

    Inventor： HENKEL CORPORATION ,  SALKA, Barry, A. ,  GESSLEIN, Bruce, W. ,  MILSTEIN, Norman

    IPC: B01J13/00

    CPC classification number: C07C69/48 ,  A61K8/06 ,  A61K8/37 ,  A61Q19/00 ,  B01F17/0092 ,  Y10S514/873 ,  Y10S516/918

    Abstract: There is provided self-emulsifying or emollient agents prepared by the process comprising reacting from about 1 mole of azelaic acid with from about 1 to about 1.25 moles of C12-18 fatty alcohol to form an azelaic monoester having general formulae (I-IV), wherein R is a C12-18 fatty alcohol, and the product containing from about 40 to about 50 weight percent of (I), from about 50 to about 60 weight percent of (II), from about 1 to about 2 weight percent of (III), and from about 0 to about 1 weight percent of (IV), all weights being based on the weight of said self-emulsifying or emollient agent. There is also provided an aqueous composition employing said agents and methods of self-emulsifying or imparting emolliency.

    Abstract translation: 提供了通过该方法制备的自乳化剂或软化剂，其包括使约1摩尔壬二酸与约1至约1.25摩尔的C 12-18脂肪醇反应，形成具有通式（I-IV）的壬二酸单酯， 其中R是C 12-18脂肪醇，并且该产品含有约40至约50重量％的（I），约50至约60重量％的（II），约1至约2重量％的 III）和约0至约1重量％的（IV），所有重量均基于所述自乳化或润肤剂的重量。 还提供了使用所述试剂的水性组合物和自乳化或赋予润肤剂的方法。

    HAIR AND SKIN CONDITIONING AGENTS AND METHODS
    6.
    发明申请
    HAIR AND SKIN CONDITIONING AGENTS AND METHODS 审中-公开
    头发和皮肤调理剂和方法

    公开(公告)号：WO1990003161A1

    公开(公告)日：1990-04-05

    申请号：PCT/US1989003803

    申请日：1989-09-05

    Applicant: INOLEX CHEMICAL COMPANY

    Inventor： INOLEX CHEMICAL COMPANY ,  GESSLEIN, Bruce, W. ,  GUTH, Jacob, J. ,  MINTZ, Gilbert, R. ,  REINHART, Gale, M. ,  SMITH, Laurence, R.

    IPC: A61K07/075

    CPC classification number: A61Q5/12 ,  A61K8/416 ,  A61K8/42 ,  Y10S514/846 ,  Y10S514/847 ,  Y10S514/848 ,  Y10S514/873

    Abstract: Alkyl or alkylamido dimethyl 2,3-dihydroxypropyl ammonium salts may be used in hair and skin conditioning compositions and methods to provide improved manageability, static control, and ease of wet and dry combing when applied to hair, particularly human scalp hair, and smooth and lubricated surfaces with pleasant after-feel when applied in topical conditioner compositions to the human skin. The hair conditioning formulations may include styling, cleaning and rinsing compositions such as gels, mousses, sprays, lotions, glazes and shampoos, while the skin conditioning compositions may include moisturizing creams and lotions, bath oils, liquid cleaners, body mousses or bath gels, as well as alcoholic or hydroalcoholic astringents, toners, pre-electric shave conditioners, after-bath splashes and fragrance products. A preferred quaternary according to the invention is oleamidoproyl dimethyl 2,3-dihydroxypropyl ammonium chloride, which forms exceptionally stable, clear, dilutable gels.

    ALPHA-AZACYCLOMETHYL QUINOLINE DERIVATIVES FOR TREATING URINARY INCONTINENCE
    7.
    发明申请
    ALPHA-AZACYCLOMETHYL QUINOLINE DERIVATIVES FOR TREATING URINARY INCONTINENCE 审中-公开
    用于治疗尿毒症的ALPHA-AZACYCLOMETHYL喹啉衍生物

    公开(公告)号：WO00046219A1

    公开(公告)日：2000-08-10

    申请号：PCT/FR2000/000192

    申请日：2000-01-28

    IPC: A61K31/4025 ,  A61K31/4725 ,  A61P1/00 ,  A61P9/00 ,  A61P13/00 ,  C07D401/06 ,  C07D409/06 ,  A61K31/47

    CPC classification number: C07D401/06 ,  Y10S514/844 ,  Y10S514/873 ,  Y10S514/937 ,  Y10S514/938 ,  Y10S514/939

    Abstract: The invention concerns compounds of formula (I) wherein: A represents either a hydrogen atom or a hydroxyl group; B represents a pyrrolidin-2-yl (D) or 2-piperidyl (E), B capable of being substituted by one or two R5 groups; R1 represents a hydrogen atom, a C1-C6 alkyl, a C2-C6 alkenyl, a C1-C2 perfluoroalkyl or a C1-C6 fluoroalkyl group; R2, R3 or R4, independently of one another, represent a hydrogen atom, a C1-C6 alkyl, group or a C2-C6 alkenyl group, or R1 and R2 can together form a C1-C6 alkylene chain, or a C3-C6 alkenylene chain; R5 represents a C1-C6 alkyl group, and R6 represents a hydrogen atom, a C1-C6 alkyl group, a C2-C6 alkenyl group, C3-C6 cycloalkyl, C3-C6 cycloalkenyl or a benzyl. Said compounds have therapeutic applications.

    Abstract translation: 本发明涉及式（I）的化合物，其中：A表示氢原子或羟基; B表示可被一个或两个R 5基团取代的吡咯烷-2-基（D）或2-哌啶基（E），B。 R1表示氢原子，C1-C6烷基，C2-C6烯基，C1-C2全氟烷基或C1-C6氟代烷基; R 2，R 3或R 4彼此独立地表示氢原子，C 1 -C 6烷基，或C 2 -C 6烯基，或者R 1和R 2可以一起形成C 1 -C 6亚烷基链或C 3 -C 6 亚烯基链; R5表示C1-C6烷基，R6表示氢原子，C1-C6烷基，C2-C6烯基，C3-C6环烷基，C3-C6环烯基或苄基。 所述化合物具有治疗应用。

    DRY EMOLLIENT COMPOSITIONS
    8.
    发明申请
    DRY EMOLLIENT COMPOSITIONS 审中-公开
    干燥的组合物

    公开(公告)号：WO9937274A3

    公开(公告)日：1999-09-30

    申请号：PCT/US9901385

    申请日：1999-01-21

    Applicant: INT FLORA TECHNOLOGIES LTD

    Inventor： ARQUETTE DEMETRIOS JAMES G ,  BROWN JIM ,  REINHARDT JOHN

    IPC: A61K8/00 ,  A61K8/02 ,  A61K8/04 ,  A61K8/19 ,  A61K8/29 ,  A61K8/30 ,  A61K8/34 ,  A61K8/36 ,  A61K8/365 ,  A61K8/37 ,  A61K8/41 ,  A61K8/44 ,  A61K8/49 ,  A61K8/64 ,  A61K8/66 ,  A61K8/67 ,  A61K8/81 ,  A61K8/86 ,  A61K8/891 ,  A61K8/894 ,  A61K8/92 ,  A61K8/96 ,  A61K8/97 ,  A61Q1/00 ,  A61Q1/02 ,  A61Q1/04 ,  A61Q1/06 ,  A61Q1/10 ,  A61Q1/12 ,  A61Q17/02 ,  A61Q17/04 ,  A61Q19/00 ,  C07C67/03 ,  C07C69/533 ,  A61K7/48

    CPC classification number: C07C69/533 ,  A61K8/025 ,  A61K8/19 ,  A61K8/29 ,  A61K8/342 ,  A61K8/345 ,  A61K8/361 ,  A61K8/365 ,  A61K8/37 ,  A61K8/375 ,  A61K8/41 ,  A61K8/44 ,  A61K8/4946 ,  A61K8/671 ,  A61K8/675 ,  A61K8/678 ,  A61K8/8152 ,  A61K8/86 ,  A61K8/891 ,  A61K8/894 ,  A61K8/922 ,  A61K2800/652 ,  A61K2800/872 ,  A61Q1/02 ,  A61Q1/04 ,  A61Q1/06 ,  A61Q1/10 ,  A61Q17/04 ,  A61Q19/00 ,  C07C67/03 ,  Y10S514/844 ,  Y10S514/873

    Abstract: Dry-feel emollient composition additives comprising jojoba oil based esters have use in personal care, cosmetic, cosmeceutical and pharmaceutical products. The composition is essentially solid at room temperature, can be provided in various shapes and sizes (especially as particulates such as spheres), and can be produced from combinations of fatty alcohols, isopropyl esters and wax esters obtained from the oil contained in the seed of the jojoba plant (Simmondsia chinensis), jojoba oil. These new compositions also increase the range of applications for cosmetic compositions through an emollient that is more polar and hydrophilic than is found in jojoba oils (which may also be referred to in the art as jojoba wax esters). The compositions comprising fatty alcohols, isopropyl esters and jojoba wax esters (jojoba oil) may be obtained by a novel process of a base catalyzed alcoholysis reaction between jojoba oil and an alcohol, such as isopropyl alcohol. These esters, whether exclusively jojoba esters or when combined with other carrier and vehicle components (including other emollients or binders) can form excellent carrier and vehicle or delivery compositions for use in the cosmetic, personal care and/or pharmaceutical field, including the cosmeceutical field where cosmetic compositions also provide pharmaceutical or other therapeutic benefits. Typical materials with which the jojoba esters may be blended in accordance with the practice of the present invention include, but are not limited to, cosmetic oils and waxes, both natural and synthetic, including hydrogenated or partially hydrogenated oils, silicone oils, mineral oils, long chain esters, vitamins (especially vitamin E), long chain fatty acids, alcohols, cosmeceuticals, pigments, botanical extracts, esters and ethers, dimers, trimers, oligomers, and polymers, and the like. These blended compositions may of course be combined with the active ingredients intended to be delivered by the compositions used in the present invention. The proportions of the jojoba esters should be chosen to provide the dry-feel to the composition which is highly desired. This will usually require at least 10 %, often at least 20 %, preferably at least 30 %, more preferably at least 40 or 50 % by weight, and most preferably at least 60, at least 70, at least 80, and at least 90 % (up to 100 % by weight) by weight of carrier material (excluding solvent and actives) in the composition.

    Abstract translation: 包含霍霍巴油基酯的干性润肤组合物添加剂可用于个人护理，化妆品，药​​妆和医药产品。 组合物在室温下基本上是固体，可以以各种形状和大小（特别是颗粒如球体）提供，并且可以由脂肪醇，异丙酯和蜡酯的组合制备，所述脂肪醇，异丙酯和蜡酯由 荷荷巴植物（Simmondsia chinensis），霍霍巴油。 这些新的组合物还通过柔软剂增加了化妆品组合物的应用范围，该润肤剂比在霍霍巴油（在本领域中也称为霍霍巴蜡酯）中所发现的更具极性和亲水性。 包含脂肪醇，异丙酯和霍霍巴蜡酯（荷荷巴油）的组合物可以通过在霍霍巴油和醇如异丙醇之间的碱催化的醇解反应的新方法获得。 这些酯，无论是单独的霍霍巴酯，还是与其他载体和载体组分（包括其它润肤剂或粘合剂）组合可以形成用于化妆品，个人护理和/或药物领域的优秀载体和载体或递送组合物，包括药妆领域 其中化妆品组合物还提供药物或其它治疗益处。 根据本发明的实践可以混合霍霍巴酯的典型材料包括但不限于天然和合成的化妆油和蜡，包括氢化或部分氢化的油，硅油，矿物油， 长链酯，维生素（特别是维生素E），长链脂肪酸，醇，药妆，色素，植物提取物，酯和醚，二聚体，三聚体，低聚物和聚合物等。 这些共混组合物当然可以与预期由本发明使用的组合物递送的活性成分组合。 应选择荷荷巴酯的比例以提供高度期望的组合物的干燥感觉。 这通常需要至少10％，通常至少20％，优选至少30％，更优选至少40或50％，最优选至少60，至少70，至少80，并且至少 90％（高达100重量％）的载体材料（不包括溶剂和活性物质）在组合物中。

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