摘要:
The present invention generally relates to microparticles and, in particular, to systems and methods for encapsulation within microparticles. In one aspect, the present invention is generally directed to microparticles containing entities therein, where the entities contain an agent that can be released from the microparticles, e.g., via diffusion. In some cases, the agent may be released from the microparticles without disruption of the microparticles. The entities may be, for instance, polymeric particles, hydrogel particles, droplets of fluid, etc. The entities may be contained within a fluid that is, in turn, encapsulated within the microparticle. The agent may be released from the entity into the fluid, and then from the fluid through the microparticle. In such fashion, the release of agent from the microparticle may be controlled, e.g., over relatively long time scales. Other embodiments of the present invention are generally directed to methods of making such microparticles, methods of using such microparticles, microfluidic devices for making such microparticles, and the like.
摘要:
The invention provides delivery systems comprised of stabilized multilamellar vesicles, as well as compositions, methods of synthesis, and methods of use thereof. The stabilized multilamellar vesicles may comprise prophylactic, therapeutic and/or diagnostic agents.
摘要:
The invention relates to a composition for treating wood comprising at least one wood preserving compound and a carrier, wherein said carrier is an emulsion or microemulsion having a water to oil ratio of greater than 30 up to 92.5 water to 7.5 to less than 70 oil, wherein the oil has a flash point above 61°C. The invention also relates to methods of treating wood with the composition.
摘要:
A microcapsule comprising a core containing a hydrophobic liquid or wax and a polymeric shell formed from: i) 1 to 20% by weight of polymerisable silane compound, ii) 1 to 94% by weight of hydrophobic mono functional ethylenically unsaturated monomer, iii) 5 to 98% by weight of polyfunctional ethylenically unsaturated monomer, and iv) 0 to 60% by weight of other mono functional monomer(s), wherein components (i), (ii), (iii) and (iv) total 100%, and in which the microcapsule also includes a hydrophilic polymer which is covalently bonded to the microcapsule. The invention includes a process for the manufacture of particles and the use of particles in artic les, such as fabrics, and coating compositions, especially for textiles.
摘要:
The present invention provides a lipid of the formula (I) R 3 R 4 N-[Y] q -(C p H 2p )-X-Linker-NR 1 R 2 (I) wherein R 3 and R 4 are independently selected from H and hydrocarbyl groups; q is an integer selected from 1 to 10; Y represents a group (C n H 2n )NR 5 , wherein (i) when q is 1, n is 2, or (ii) when q is greater than 1, each Y may be the same or different and each n is an integer independently selected from 1 to 10, with the proviso that for at least one unit Y, n is 2, and (iii) each R 5 is independently selected from H and hydrocarbyl groups; p is an integer selected from 1 to 10; X is an optional group selected from -NR 7 -, -C(=O)-N R 8 -, -NR 9 -C(=O)-, -C(=O)-, -O-, and -NR 10 -C(=0)0-, wherein each R 7 , R 8 , R 9 and R 10 is independently selected from H and hydrocarbyl groups, Linker is an optional group selected from amino acid residues, peptide residues and groups of the formula -(OCH 2 CH 2 ) 1-10 , -NR 6 -(CvH 2v )-C(=O)-, wherein R 6 is H or a hydrocarbyl group and v is an integer selected from 1 to 11, and -C(=0)-(CH 2 ) 0-10 -CH 2 -C(=0)-; R 1 is selected from acyclic groups having from 4 to 30 carbon atoms; and R 2 is selected from H and acyclic groups having from 4 to 30 carbon atoms. Said lipids can be used in a delivery vehicle (e.g. micelle or liposome) for the delivery of one or more (therapeutic or diagnostic) agents.
摘要翻译:本发明提供式(I)的脂类R 3 R 4 N - [Y] q - (C p 其中R 3是氢原子,其中R 3,R 2,R 2,R 2,R 2,R 2, 和R 4独立地选自H和烃基; q是从1至10的整数; Y表示一个基团(C n H n H 2n)NR 5,其中(i)当q为1时,n为2或(ii )当q大于1时,每个Y可以相同或不同,并且每个n是独立地选自1至10的整数,条件是对于至少一个单元Y,n是2,和(iii)每个R 5个独立地选自H和烃基; p是从1到10的整数; X是选自-NR 7 - , - C(= O)-NR 8 - , - NR 9 -C( = O) - , - C(= O) - , - O-和-NR 10 -C(= O)O-,其中每个R 7,R R 9,R 9和R 10独立地选自H和烃基,连接子是选自氨基酸残基,肽残基的任选基团 和式 - (OCH 2 CH 2 CH 2)1 - , - NR 6 - (C v H C(= O) - ,其中R 6为H或烃基,v为选自1至11的整数,且-C(= O ) - (CH 2 SUB>) 0-10 SUB> -CH 2 SUB> -C(= O) - ; R 1选自具有4至30个碳原子的无环基团; R 2选自H和具有4-30个碳原子的无环基。 所述脂质可用于递送载体(例如胶束或脂质体)中以递送一种或多种(治疗或诊断)试剂。
摘要:
Microencapsulated delivery vehicles comprising an active agent are disclosed. The microencapsulated delivery vehicles may be introduced into products such that, upon activation, the product provides a functional benefit to a substrate, such as a user's skin.
摘要:
A microcapsule comprising A) a core containing a hydrophobic liquid or wax, B) a polymeric shell comprising a) a polymer formed from a monomer mixture containing: i) 1 to 95% by weight of a hydrophobic mono functional ethylenically unsaturated monomer, ii) 5 to 99% by weight of a polyfunctional ethylenically unsaturated monomer, and iii) 0 to 60% by weight of other mono functional monomer, and b) a further hydrophobic polymer which is insoluble in the hydrophobic liquid or wax. The invention includes a process for the manufacture of particles and the use of particles in articles, such as fabrics, and coating compositions, especially for textiles.
摘要:
The invention relates to a process for separating a dispersed phase from a continuous phase comprising the steps of i) contacting said phases with an effective amount of nanoparticles; ii) applying a magnetic field gradient to the obtained system; iii) separating the obtained phases wherein said nanoparticles are of the core shell type, said core consists of a metal or alloy having soft magnetic properties and said shell contains a graphene layers which are optionally functionalized; to new nanoparticles and method of manufacturing such nanoparticles.
摘要:
The present invention relates to nano structures of metal oxides having a nanostructured shell (or wall), and an internal space or void. Nanostructures may be nanoparticles, nanorod/belts/arrays, nanotubes, nanodisks, nanoboxes, hollow nanospheres, and mesoporous structures, among other nanostructures. The nanostructures are composed of polycrystalline metal oxides such as SnO2. The nanostructures may have concentric walls which surround the internal space of cavity. There may be two or more concentric shells or walls. The internal space may contain a core such ferric oxides or other materials which have functional properties. The invention also provides for a novel, inexpensive, high-yield method for mass production of hollow metal oxide nanostructures. The method may be template free or contain a template such as silica. The nanostructures prepared by the methods of the invention provide for improved cycling performance when tested using rechargeable lithium- ion batteries.