公开(公告)号：WO2022029164A1

公开(公告)日：2022-02-10

申请号：PCT/EP2021/071743

申请日：2021-08-04

Applicant: ASCENSIA DIABETES CARE HOLDINGS AG

Inventor： WU, Huan-Ping ,  CERUTTI, Mark D. ,  HARRISON, Bern

IPC: A61B5/145 ,  A61B5/1495 ,  A61B2560/0223 ,  A61B5/0002 ,  A61B5/1451 ,  A61B5/14532 ,  A61B5/1486 ,  A61B5/14865 ,  A61B5/6801 ,  A61B5/72 ,  A61B5/7228 ,  G01N33/48707 ,  G01N33/49 ,  G16H40/40 ,  G16H40/67 ,  G16H50/30 ,  G16H50/70

Abstract: A method of determining glucose values during continuous glucose monitoring (CGM) measurements includes providing a CGM device including a sensor, a memory, and a processor; applying a constant voltage potential to the sensor; measuring a primary current signal resulting from the constant voltage potential and storing the measured primary current signal in the memory; applying a probing potential modulation sequence to the sensor; measuring probing potential modulation current signals resulting from the probing potential modulation sequence and storing measured probing potential modulation current signals in the memory; determining an initial glucose concentration based on a conversion function and a ratio of measured probing potential modulation current signals; determining a connection function value based on the primary current signal and a plurality of the probing potential modulation current signals; and determining a final glucose concentration based on the initial glucose concentration and the connection function value. Other aspects are disclosed.

公开(公告)号：WO2022011420A1

公开(公告)日：2022-01-20

申请号：PCT/AU2021/050754

申请日：2021-07-14

Applicant: CENTRE FOR EYE RESEARCH AUSTRALIA LIMITED

Inventor： HADOUX, Xavier ,  JANNAUD, Maxime ,  LABRECQUE, Francis ,  VAN WIJNGAARDEN, Peter

IPC: A61B3/14 ,  A61B3/12 ,  A61B3/10 ,  A61B3/15 ,  G01J3/26 ,  G01J3/28 ,  G02B21/00 ,  G02B27/09 ,  A61B2560/0223 ,  A61B2576/02 ,  A61B3/0008 ,  A61B3/0025 ,  A61B3/1015 ,  A61B3/102 ,  A61B3/13 ,  A61B5/0033 ,  A61B5/0075 ,  A61B5/0082 ,  G01J2003/1213 ,  G01J2003/1234 ,  G01J3/2823 ,  H04N5/232125 ,  H04N5/235 ,  H04N5/2354 ,  H04N5/351 ,  H04N5/3537 ,  H04N5/355 ,  H04N5/35527 ,  H04N9/04517 ,  H04N9/0455 ,  H04N9/04553

Abstract: Described herein is an ocular fundus imaging apparatus (11) including and an illumination module (140) and an imaging module (141). The illumination module (140) includes light sources (103, 104) configured to generate light at wavelengths within a desired spectral range. A first optical assembly is provided to shape and direct the light onto an eye (102) of a subject. A tuneable bandpass filter (109) selects a wavelength sub-interval within the desired spectral range. The imaging module (141) includes a second optical assembly to collect light returned from the eye (102) of the subject and to project the returned light from the eye (102) onto an image sensor (113). The second optical assembly includes one or more optical elements capable of compensating for ocular variation. The image sensor (113) is configured to image the returned light to generate an image of the ocular fundus at the wavelength sub-interval.

公开(公告)号：WO2019109574A1

公开(公告)日：2019-06-13

申请号：PCT/CN2018/083999

申请日：2018-04-22

Applicant: 北京师范大学

Inventor： 朱朝喆

IPC: A61B8/08 ,  G06T7/00 ,  A61B2560/0223 ,  A61B5/05 ,  A61B5/4064 ,  G06F3/03545 ,  G06T17/20 ,  G06T19/00 ,  G06T19/20 ,  G06T2207/10088 ,  G06T2207/30016 ,  G06T2210/41 ,  G06T2210/56 ,  G06T2219/2021 ,  G06T7/143

Abstract: 一种经颅脑图谱生成方法和一种面向群体应用的经颅脑图谱预测方法及相应的经颅脑图谱预测装置。该经颅脑图谱生成方法包括如下步骤：在个体层面创建颅面坐标系；建立用于连接颅骨位置与大脑位置的经颅映射系统；使用马尔可夫链中的两步随机过程构建经颅脑图谱。经颅脑图谱将不可见的脑内图谱标号信息投射到可见的头皮上来，使得研究者或者医生可以使用这些脑结构和功能图谱信息，大大提升了脑图谱在经颅脑映射技术使用中的作用。

公开(公告)号：WO2022072528A2

公开(公告)日：2022-04-07

申请号：PCT/US2021/052695

申请日：2021-09-29

Applicant: BARD ACCESS SYSTEMS, INC.

Inventor： SOWARDS, Steffan ,  MCLAUGHLIN, William, Robert ,  MISENER, Anthony, K. ,  MESSERLY, Shayne

IPC: A61B5/00 ,  A61B90/98 ,  A61B1/05 ,  A61B1/00059 ,  A61B1/00165 ,  A61B1/3137 ,  A61B2090/0804 ,  A61B2090/0805 ,  A61B2560/0223 ,  A61B2562/085 ,  A61B5/6852 ,  G06K7/10366 ,  G16H40/63

Abstract: Disclosed herein are RFID enabled medical device systems (100) including an RFID emitter (120) configured to provide an interrogation signal that impinges on an RFID tag (140A, 140B) associated with a medical device (130) to trigger a response signal. The response signal can indicate and presence or absence of the medical device (130) proximate to the RFID emitter (120). A console (110) communicatively coupled to the RFID emitter (120) can determine, record, and analyze procedural or usage information about the medical device (130). Further information about the medical device can be encoded within the response signal and provided to the console. Console settings can be automatically updated based on the information within the response signal. Additional modalities are also contemplated including optical image recognition of medical device kits. Further AR viewers can provide image overlays to guide a user in correct procedure. Procedural compliance can be automatically recorded and monitored.

公开(公告)号：WO2021248248A1

公开(公告)日：2021-12-16

申请号：PCT/CA2021/050796

申请日：2021-06-11

Applicant: DIAMENTIS INC.

Inventor： HARITON, Claude

IPC: A61B5/398 ,  A61B3/10 ,  G16H50/20 ,  G16H50/50 ,  G06N20/00 ,  A61B2560/0223 ,  A61B5/7207

Abstract: There is disclosed a method and system for generating retinal signal data. Calibration data corresponding to an individual may be received. A threshold impedance may be determined based on the calibration data. Retinal signal data corresponding to the individual may be received. The impedance of the circuit collecting the retinal signal data may be compared to the threshold impedance to determine whether the retinal signal data contains any artifacts. A portion of the retinal signal data corresponding to the artifacts may be removed from the retinal signal data.

公开(公告)号：WO2021127207A1

公开(公告)日：2021-06-24

申请号：PCT/US2020/065652

申请日：2020-12-17

Applicant: EMPNIA INC.

Inventor： BHATTACHARYA, Manojeet

IPC: A61B5/021 ,  A61B5/1455 ,  A61B5/145 ,  A61B5/01 ,  A61B5/00 ,  A61B2560/0223 ,  A61B2562/0233 ,  A61B5/0002 ,  A61B5/02055 ,  A61B5/02427 ,  A61B5/14532 ,  A61B5/14552 ,  A61B5/681 ,  A61B5/7425

Abstract: A health monitoring device for detecting blood pressure having a blood pressure sensor including a first fiber Bragg grating (FBG) with a refractive index is configured to be placed in contact with a person's skin approximate to an artery or vein. A baseline sensor that includes a second fiber Bragg grating (FBG) also having a refractive index is configured to be placed in contact with a person's skin away from an artery or vein to provide a baseline refractive index. The device pulses light waves through the FBGs to provide a processor with reading of the refractive index from the FBGs. Based on the effective shifts of the Bragg wavelength due to axial strain on the FBGs, a blood pressure estimator estimates systolic and diastolic blood pressure based on a calibration curve comparing pressure against strain.

公开(公告)号：WO2022264078A1

公开(公告)日：2022-12-22

申请号：PCT/IB2022/055576

申请日：2022-06-16

Applicant: MEDICAL MICROINSTRUMENTS S.P.A.

Inventor： TANZINI, Matteo ,  SIMI, Massimiliano ,  PRISCO, Giuseppe Maria ,  PROCTOR, Michael John

IPC: A61B34/00 ,  A61B34/37 ,  A61B2034/715 ,  A61B2560/0223 ,  A61B34/71

Abstract: A method is described for conditioning a surgical instrument 20 of a robotic surgery system 1, which can be carried out before using the surgical instrument 20. The method is applied to a surgical instrument 20 comprising an articulated end-effector 40 having at least one degree of freedom (P, Y, G), and further comprises at least one tendon 31, 32, 33, 34, 35, 36, operatively connectable with a respective at least one motorized actuator 1 1, 12, 13, 14, 15, 16 of the robotic surgery system 1. The at least one tendon 31, 32, 33, 34, 35, 36 is mounted to the surgical instrument 20 so as to be operatively connectable to both a respective motorized actuator, among the aforesaid at least one transmission element, and to at least one degree of freedom of the aforesaid at least one degree of freedom P, Y, G of the articulated end-effector 40. The aforesaid at least one degree of freedom P, Y, G operatively connectable to the at least one tendon is adapted to be mechanically activated by an action of the at least one respective motorized actuator 11, 12, 13, 14, 15, 16 by means of the aforesaid at least one tendon 31, 32, 33, 34, 35, 36 which is operatively connectable thereto. The method comprises the following steps: (i) locking at least one degree of freedom of the aforesaid at least one degree of freedom P, Y, G of the end-effector 40; (ii) tensile-stressing the respective at least one tendon, operatively connected to the aforesaid at least one locked degree of freedom, by applying a conditioning force (Fref), according to at least one time cycle, to the respective at least one tendon to be stressed under tensile load; The aforesaid at least one time cycle comprises: - at least one low-load period, in which a low conditioning force Flow is applied to the aforesaid respective tendon, which results in a respective low tensile load on the respective tendon; - at least one high-load period, in which a high conditioning force Fhigh is applied to the aforesaid respective tendon, which results in a respective high tensile load on the respective tendon.

公开(公告)号：WO2022029165A1

公开(公告)日：2022-02-10

申请号：PCT/EP2021/071744

申请日：2021-08-04

Applicant: ASCENSIA DIABETES CARE HOLDINGS AG

Inventor： WU, Huan-Ping

IPC: A61B5/145 ,  A61B5/1495 ,  A61B2560/0223 ,  A61B5/0002 ,  A61B5/1451 ,  A61B5/14532 ,  A61B5/1486 ,  A61B5/14865 ,  A61B5/6801 ,  A61B5/72 ,  A61B5/7228 ,  G01N33/48707 ,  G01N33/49 ,  G16H40/40 ,  G16H40/67 ,  G16H50/30 ,  G16H50/70

Abstract: A biosensor system is configured to establish a steady-state condition and alternate between the steady-state condition and a non-steady-state condition to determine an analyte concentration. The biosensor system includes an electrode system having at least one working electrode and one counter electrode. The working electrode is covered with an analyte catalyzing layer for converting an analyte into measurable species. A membrane system encompasses the electrode system and comprises an analyte permeable membrane. The membrane has an analyte permeability with lower analyte solubility than an analyte solubility outside the membrane. The membrane is configured to trap a measureable species within the membrane such that a steady-state of the measurable species resulting from the analyte is established near the electrode surface. A bias circuit is configured to apply a potential modulation sequence to the working electrode to cause alternating of steady-state and non-steady-state conditions within the electrode system for analyte concentration determination.

公开(公告)号：WO2021198872A1

公开(公告)日：2021-10-07

申请号：PCT/IB2021/052565

申请日：2021-03-29

Applicant: BIOSENSE WEBSTER (ISRAEL) LTD.

Inventor： GOVARI, Assaf

IPC: G06T7/33 ,  A61B2034/2051 ,  A61B2034/2063 ,  A61B2034/2065 ,  A61B2034/2072 ,  A61B2560/0223 ,  A61B2560/0242 ,  A61B34/20 ,  G06T2207/10072 ,  G06T2207/10132 ,  G06T2207/30004 ,  G06T2207/30201 ,  G06T7/70

Abstract: A method includes receiving multiple measurements, which are acquired using a registration tool including an ultrasound (US) transducer and a position sensor of a position-tracking system. The measurements are acquired by positioning the registration tool, while maintaining a gap from skin tissue, at multiple respective locations on a patient head and acquiring respective position measurements of the position sensor and respective US measurements of the skin tissue at the locations. First positions are calculated based on the position measurement and the US measurements obtained using the registration tool. Second positions are identified in an anatomical image of the patient head. The anatomical image is registered with a coordinate system of the position tracking system, by correlating the first positions and the second positions, so as to enable tracking a medical instrument, which is inserted into the patient head and includes another position sensor.

公开(公告)号：WO2021194622A1

公开(公告)日：2021-09-30

申请号：PCT/US2021/015051

申请日：2021-01-26

Applicant: MEDTRONIC MINIMED, INC.

Inventor： HEFNER, Jesse ,  MAIRS, Nicholas S. ,  ROSS, Brian ,  HAGGERTY, Matthew N.

IPC: A61B5/145 ,  A61B5/1495 ,  A61B2560/0223 ,  A61B2562/0219 ,  A61B5/0022 ,  A61B5/0024 ,  A61B5/0531 ,  A61B5/14532 ,  A61B5/6802

Abstract: A method of measuring a physiological characteristic of a user obtains first calibrating sensor data indicative of an analyte level of the user, and produced in response to operation of a continuous analyte sensor device during a calibration period, and obtains second calibrating sensor data indicative of status or condition of the user, and produced in response to operation of a noninvasive sensor device, concurrently with operation of the continuous analyte sensor device, during the calibration period. A correlation measurement is calculated by comparing the first calibrating sensor data against the second calibrating sensor data. When the correlation measurement exceeds a threshold value, a transfer function is generated to calculate estimated values of the analyte level as a function of sensor data from the noninvasive sensor device. The transfer function is provided to a client device associated with the user.