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    AZO HETEROCYCLIC DYES AND THEIR BIOLOGICAL CONJUGATES
    1.
    发明申请
    AZO HETEROCYCLIC DYES AND THEIR BIOLOGICAL CONJUGATES 审中-公开
    AZO杂环染料及其生物学结合

    公开(公告)号：WO2010141731A1

    公开(公告)日：2010-12-09

    申请号：PCT/US2010/037273

    申请日：2010-06-03

    Applicant: AAT BIOQUEST, INC. ,  DIWU, Zhenjun ,  LIAO, Jinfang

    Inventor： DIWU, Zhenjun ,  LIAO, Jinfang

    IPC: C09B44/10

    CPC classification number: C09B29/0085 ,  A61K49/0017

    Abstract: Azo heterocyclic compounds that are substantially non-fluorescent or only weakly fluorescent useful as energy acceptors. The chemically reactive compounds possess utility for labeling a wide variety of substances, including biomolecules with the resulted conjugates being highly useful for a variety of energy-transfer assays and applications. The biological conjugates of the disclosure exhibit little or no observable fluorescence and their fluorescence is significantly increased upon a biological stimulation.

    Abstract translation: 基本上是非荧光的或仅用作能量受体的弱荧光的偶氮杂环化合物。 化学反应性化合物具有用于标记多种物质（包括生物分子）的效用，所得到的缀合物对于各种能量转移测定和应用是非常有用的。 本公开的生物共轭物显示很少或不可观察到的荧光，并且在生物刺激下其荧光显着增加。

    CATIONIC DIMERIC DYES
    2.
    发明申请
    CATIONIC DIMERIC DYES 审中-公开
    阳光二极管

    公开(公告)号：WO2004083312A2

    公开(公告)日：2004-09-30

    申请号：PCT/EP2004/050268

    申请日：2004-03-08

    Applicant: CIBA SPECIALTY CHEMICALS HOLDING INC. ,  ELIU, Victor, Paul ,  FRÖHLING, Beate

    Inventor： ELIU, Victor, Paul ,  FRÖHLING, Beate

    IPC: C09B44/10

    CPC classification number: C09B44/10 ,  A61K8/4926 ,  A61K8/4946 ,  A61Q5/065 ,  Y10S8/919

    Abstract: The present invention relates to novel cationic dye of formula (1) and (1 a) wherein A is an organic radical of formula (2) or (3) wherein R 1 and R 2 are each independently of the other unsubstituted or substituted C 1 -C 14 alkyl or an aryl radical, R 3 is hydrogen, unsubstituted or substituted C 1 -C 14 alkyl, unsubstituted or substituted C 1 -C 14 alkoxy, cyan or halogenid, R 4 is hydrogen, unsubstituted or substituted C 1 -C 14 alkyl or an aryl radical, and X is an anion. Further, the present invention relates to compositions thereof, especially comprising other dyes, to processes for the preparation thereof and to the use thereof in the dyeing of organic material, such as keratin, wool, leather, paper, silk, cellulose or polyamides, and preferably human hair.

    Abstract translation: 本发明涉及式（1）和（1a）的新型阳离子染料，其中A是式（2）或（3）的有机基团，其中R 1和R 2各自独立地是其它未取代或取代的C 1 -C 14烷基或 芳基，R 3为氢，未取代或取代的C 1 -C 14烷基，未取代或取代的C 1 -C 14烷氧基，氰基或卤素，R 4为氢，未取代或取代的C 1 -C 14烷基或芳基，X为阴离子。 此外，本发明涉及其组合物，特别是其它染料，其制备方法及其在染色有机材料如角蛋白，羊毛，皮革，纸，丝，纤维素或聚酰胺中的用途，以及 优选人发。

    CATIONIC DIMERIC DYES
    4.
    发明申请
    CATIONIC DIMERIC DYES 审中-公开
    阳光二极管

    公开(公告)号：WO2004083312A3

    公开(公告)日：2005-11-17

    申请号：PCT/EP2004050268

    申请日：2004-03-08

    Applicant: CIBA SC HOLDING AG ,  ELIU VICTOR PAUL ,  FROEHLING BEATE

    Inventor： ELIU VICTOR PAUL ,  FROEHLING BEATE

    IPC: A61K8/49 ,  A61Q5/06 ,  A61Q5/10 ,  C09B44/10 ,  A61K7/13

    CPC classification number: C09B44/10 ,  A61K8/4926 ,  A61K8/4946 ,  A61Q5/065 ,  Y10S8/919

    Abstract: The present invention relates to novel cationic dye of formula (1) and (1 a) wherein A is an organic radical of formula (2) or (3) wherein R1 and R2 are each independently of the other unsubstituted or substituted C1-C14alkyl or an aryl radical, R3 is hydrogen, unsubstituted or substituted C1-C14alkyl, unsubstituted or substituted C1-C14alkoxy, cyan or halogenid, R4 is hydrogen, unsubstituted or substituted C1-C14alkyl or an aryl radical, and X is an anion. Further, the present invention relates to compositions thereof, especially comprising other dyes, to processes for the preparation thereof and to the use thereof in the dyeing of organic material, such as keratin, wool, leather, paper, silk, cellulose or polyamides, and preferably human hair.

    Abstract translation: 本发明涉及式（1）和（1a）的新型阳离子染料，其中A是式（2）或（3）的有机基团，其中R 1和R 2各自独立地是其它未取代或取代的C 1 -C 14烷基或 芳基，R 3为氢，未取代或取代的C 1 -C 14烷基，未取代或取代的C 1 -C 14烷氧基，氰基或卤素，R 4为氢，未取代或取代的C 1 -C 14烷基或芳基，X为阴离子。 此外，本发明涉及其组合物，特别是其它染料，其制备方法及其在染色有机材料如角蛋白，羊毛，皮革，纸，丝，纤维素或聚酰胺中的用途，以及 优选人发。

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