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    ELECTROCHEMICAL AFFINITY ASSAY
    13.
    发明公开
    ELECTROCHEMICAL AFFINITY ASSAY 有权
    电化学亲和力测定

    公开(公告)号：EP1105736A1

    公开(公告)日：2001-06-13

    申请号：EP99942403.9

    申请日：1999-08-24

    申请人： Therasense, Inc.

    发明人： HELLER, Adam ,  CAMPBELL, Charles, N.

    IPC分类号： G01N33/543 ,  G01N27/327 ,  C12Q1/00 ,  C12Q1/26 ,  C12Q1/28

    CPC分类号： G01N33/543 ,  C12Q1/002 ,  C12Q1/005 ,  G01N33/5438 ,  Y10S435/817 ,  Y10S436/806

    摘要： An electrochemical affinity assay system for detection of ligand-ligand receptor binding. The first member of a ligand-ligand receptor pair is immobilized in a redox polymer. The second member is bound then to the first. The third member is labeled with the detection marker horseradish peroxidase or soybean peroxidase. Binding of the labeled third member to the electrode via the second member results in electrical contact between the peroxidase and the redox polymer, causing the electrical connection of the reaction centers of the peroxidase label to the electrode through the conducting redox polymer. Such connection converts the film to a catalyst for the electroreduction of the hydrogen peroxide produced within the film by the immobilized substrate-generating enzyme.

    ELECTROCHEMICAL ANALYTE SENSOR
    14.
    发明公开
    ELECTROCHEMICAL ANALYTE SENSOR 有权
    电化学传感器分析物的检测

    公开(公告)号：EP1060394A2

    公开(公告)日：2000-12-20

    申请号：EP99904211.2

    申请日：1999-01-21

    申请人： Therasense, Inc.

    发明人： SAY, James ,  TOMASCO, Michael, F. ,  HELLER, Adam ,  GAL, Yoram ,  ARIA, Behrad ,  HELLER, Ephraim ,  PLANTE, Phillip, J. ,  VREEKE, Mark, S.

    IPC分类号： G01N33/487 ,  C12Q1/00

    CPC分类号： A61B5/14532 ,  A61B5/01 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/14735 ,  A61B5/1486 ,  A61B5/14865 ,  C12Q1/001 ,  C12Q1/006

    摘要： An electrochemical analyte sensor formed using conductive traces on a substrate can be used for determining and/or monitoring a level of analyte in in vitro or in vivo analyte-containing fluids. For example, an implantable sensor may be used for the continuous or automatic monitoring of a level of an analyte, such as glucose, lactate, or oxygen, in a patient. The electrochemical analyte sensor includes a substrate and conductive material disposed on the substrate, the conductive material forming a working electrode. In some sensors, the conductive material is disposed in recessed channels formed in a surface of the sensor. An electron transfer agent and/or catalyst may be provided to facilitate the electrolysis of the analyte or of a second compound whose level depends on the level of the analyte. A potential is formed between the working electrode and a reference electrode or counter/reference electrode and the resulting current is a function of the concentration of the analyte in the body fluid.

    METHOD AND SYSTEM FOR PROVIDING DATA COMMUNICATION IN CONTINUOUS GLUCOSE MONITORING AND MANAGEMENT SYSTEM
    18.
    发明公开
    METHOD AND SYSTEM FOR PROVIDING DATA COMMUNICATION IN CONTINUOUS GLUCOSE MONITORING AND MANAGEMENT SYSTEM 审中-公开
    方法和系统提供数据通信在连续BLUTZUCKERÜBERWACHUNGS-与管理系统

    公开(公告)号：EP1718198A4

    公开(公告)日：2008-06-04

    申请号：EP05723142

    申请日：2005-02-16

    申请人： THERASENSE INC

    发明人： SLOAN MARK K

    IPC分类号： A61B5/00 ,  G06F19/00

    CPC分类号： A61M5/1723 ,  A61B5/0002 ,  A61B5/01 ,  A61B5/14532 ,  A61M2205/3592 ,  G06F19/3418 ,  H04B7/24 ,  H04L7/002 ,  H04L7/0079 ,  H04L7/0091

    摘要： Method and system for providing data monitoring and management including RF communication link over which a transmitter and a receiver is configured to communicate, the transmitter configured to periodically transmit a data packet associated with a detected analyte level received from an analyte sensor, and the receiver configured to identify the transmitter as the correct transmitter for which it is configured to receive the data packets, and to continue to receive the data packets from the transmitter once the transmitter identification has been verified, is provided.

    摘要翻译： 方法和系统，用于提供数据的监测和管理，包括在其一个发射机和一个接收机被配置为通信RF通信链路，配置为周期性地发送与检测到的分析物相关联的数据包从在分析物传感器的接收电平的发送器，和配置的接收器 识别发射机为所配置接收数据包，并继续从发射器接收到的数据包，一旦发射器标识已被验证，提供正确的发射机。

    METHOD AND APPARATUS FOR PROVIDING SENSOR GUARD FOR DATA MONITORING AND DETECTION SYSTEMS
    20.
    发明公开
    METHOD AND APPARATUS FOR PROVIDING SENSOR GUARD FOR DATA MONITORING AND DETECTION SYSTEMS 审中-公开
    方法和设备提供保护传感器用于检测系统和数据监控

    公开(公告)号：EP1755443A2

    公开(公告)日：2007-02-28

    申请号：EP05738702.9

    申请日：2005-04-14

    申请人： Therasense, Inc.

    发明人： REGGIARDO, Christopher, V.

    IPC分类号： A61B5/00 ,  A61B5/05

    CPC分类号： A61B5/14865 ,  A61B5/14532 ,  A61B2562/0209 ,  A61B2562/043 ,  A61B2562/046 ,  A61B2562/182

    摘要： Method and apparatus for providing sensor guard for data monitoring and detection system having a sensor for detecting one or more glucose levels, the sensor including a work electrode disposed on a base material, a reference electrode disposed on the base material, and a guard electrode disposed on the base material, where the guard electrode is maintained substantially at equipotential to the work electrode, and a transmitter operatively coupled to the work electrode and the reference electrode of the sensor for receiving said detected glucose levels, where the transmitter is further configured to transmit a respective signal corresponding to each of the detected glucose levels using a data transmission protocol including wireless data transmission protocols, to a receiver which is configured to receive the transmitted signals corresponding to said detected glucose levels is provided. The method and apparatus may also include insulin administration unit such as an insulin pump configured to be in data communication with the transmitter and/or the receiver for administering an appropriate insulin dosage based on the measured glucose levels.