公开(公告)号：EP2039298A2

公开(公告)日：2009-03-25

申请号：EP08021732.6

申请日：2003-05-30

申请人： Vidacare Corporation

发明人： Miller, Larry J

IPC分类号： A61B10/00 ,  A61B17/34

CPC分类号： A61B17/1671 ,  A61B10/025 ,  A61B10/0283 ,  A61B17/1613 ,  A61B17/1637 ,  A61B17/32002 ,  A61B17/32053 ,  A61B17/3423 ,  A61B17/3472 ,  A61B17/3476 ,  A61B17/3496 ,  A61B50/33 ,  A61B90/11 ,  A61B90/70 ,  A61B2010/0208 ,  A61B2010/0258 ,  A61B2017/00398 ,  A61B2017/0046 ,  A61B2017/00734 ,  A61B2017/320024 ,  A61B2017/3405 ,  A61B2050/3008 ,  A61B2090/034 ,  A61B2090/0813 ,  A61B2217/005 ,  A61M1/008 ,  A61M5/158 ,  A61M2005/1581 ,  A61M2005/1585 ,  A61M2210/02

摘要： An apparatus and method for penetrating bone marrow is provided. The apparatus may include a housing such as a handheld body, a penetrator assembly, a connector that releasably attaches the penetrator assembly to a drill shaft, a gear mechanism, a motor and a power supply and associated circuitry operable to power the motor. The penetrator assembly may include a removable inner trocar and an outer penetrator or needle. It may also include a grooved trocar that allows bone chips to be expelled as the apparatus is inserted into bone marrow. Various connectors are provided to attach the penetrator assembly to the drill shaft.

摘要翻译： 提供了一种穿透骨髓的装置和方法。 该装置可以包括诸如手持式主体的壳体，穿透器组件，将穿透组件可释放地附接到钻杆轴的连接器，齿轮机构，马达和电源以及可操作以对马达供电的相关联的电路。 穿透器组件可以包括可移除的内套针和外穿刺器或针。 它还可以包括带槽的套管针，其允许在设备插入骨髓时将骨屑排出。 提供各种连接器以将穿透组件附接到钻杆轴。

公开(公告)号：EP1976458A2

公开(公告)日：2008-10-08

申请号：EP07710361.2

申请日：2007-01-29

申请人： Medicinelodge, Inc.

发明人： GOBLE, E. Marlowe ,  LEWIS, Chad E. ,  JUSTIN, Daniel F. ,  SINNOTT, M. Mary ,  GERBEC, Daniel E. ,  MOHR, Karen E. ,  FALLIN, T. Wade

IPC分类号： A61F2/28

CPC分类号： A61F2/3859 ,  A61B17/60 ,  A61B17/7001 ,  A61B17/80 ,  A61B17/86 ,  A61B2017/00004 ,  A61F2/0059 ,  A61F2/12 ,  A61F2/2803 ,  A61F2/30721 ,  A61F2/3099 ,  A61F2/32 ,  A61F2/34 ,  A61F2/36 ,  A61F2/3662 ,  A61F2/38 ,  A61F2/3804 ,  A61F2/3877 ,  A61F2/389 ,  A61F2/40 ,  A61F2/4081 ,  A61F2/4202 ,  A61F2/4261 ,  A61F2/4425 ,  A61F2/447 ,  A61F2002/2807 ,  A61F2002/30125 ,  A61F2002/30131 ,  A61F2002/30429 ,  A61F2002/30449 ,  A61F2002/30489 ,  A61F2002/305 ,  A61F2002/30626 ,  A61F2002/30677 ,  A61F2002/3068 ,  A61F2002/30785 ,  A61F2002/30787 ,  A61F2002/30822 ,  A61F2002/30878 ,  A61F2002/30884 ,  A61F2002/30904 ,  A61F2002/30991 ,  A61F2002/30993 ,  A61F2002/3401 ,  A61F2002/3611 ,  A61F2002/3625 ,  A61F2002/3631 ,  A61F2002/3813 ,  A61F2002/3822 ,  A61F2002/3831 ,  A61F2002/4018 ,  A61F2002/4029 ,  A61F2002/4205 ,  A61F2002/4207 ,  A61F2002/4264 ,  A61F2002/443 ,  A61F2002/4475 ,  A61F2220/0025 ,  A61F2220/005 ,  A61F2230/0008 ,  A61F2230/0013 ,  A61F2250/0068 ,  A61M5/14244 ,  A61M2210/02

摘要： The present invention provides integration between an implant system and therapeutic agent delivery system. The implant may include a prosthesis that restores biomechanical function while decreasing long-term disability and pain by replacing damaged or degenerate tissues, or a reconstructive implant such as a bone plate. The therapeutic agent delivery system may include one or more channels either permanently or reversibly attached to the implant. The channels may receive medication from an external pump via a percutaneous catheter. The channels deliver the medication to one or more medicating surfaces of the implant to treating proximate tissues.

公开(公告)号：EP1919538A2

公开(公告)日：2008-05-14

申请号：EP06774203.1

申请日：2006-06-27

申请人： Vidacare Corporation

发明人： MILLER, Larry J. ,  BOLLETER, David S ,  SCHWIMMER, Charles M. ,  WILK, Robert A

IPC分类号： A61M5/24

CPC分类号： A61M5/1454 ,  A61B17/32002 ,  A61B17/32053 ,  A61B17/3403 ,  A61B17/3472 ,  A61B17/3476 ,  A61B90/11 ,  A61B2017/3413 ,  A61B2090/034 ,  A61M5/158 ,  A61M5/2033 ,  A61M5/24 ,  A61M5/31511 ,  A61M5/3291 ,  A61M5/34 ,  A61M2005/1581 ,  A61M2005/1585 ,  A61M2005/3103 ,  A61M2005/3289 ,  A61M2210/02

摘要： A cartridge assembly for delivering a quantity of medication to bone marrow of a bone comprising a fluid reservoir (132; 132a) having a first end and a second end; a hollow, bone penetrating needle (160) releasably engaged with the first end of the fluid reservoir (132; 132a), the needle (160) operable to penetrate into the bone and bone marrow; a plunger assembly (82) including a plunger shaft (142) and a piston (144) slidably disposed in the fluid reservoir (132; 132a); a drive connector (150) attached to the second end of the fluid reservoir (132; 132a) opposite from the bone penetrating needle (160); and a portion of the plunger shaft (140) extending from the second end of the fluid reservoir (132; 132a), where the needle (160) is operable to be disengaged from the fluid reservoir (132; 132a) when the needle (160) has penetrated into the bone and bone marrow.

公开(公告)号：EP1463463B1

公开(公告)日：2008-02-27

申请号：EP02773895.4

申请日：2002-10-24

申请人： Kyphon Inc.

发明人： STEVENS, Sheila, S. ,  BOUCHER, Ryan, P. ,  FOLLMER, Lulu ,  REISS, Paul ,  ICO, Cesar ,  TALMADGE, Karen, D. ,  REILEY, Mark, A. ,  SCHOLTEN, Arie

IPC分类号： A61F2/44

CPC分类号： A61B17/8866 ,  A61B10/025 ,  A61B17/00234 ,  A61B17/02 ,  A61B17/7097 ,  A61B17/72 ,  A61B17/7275 ,  A61B17/8805 ,  A61B17/8855 ,  A61B50/33 ,  A61B90/39 ,  A61B90/94 ,  A61B2010/0258 ,  A61B2017/00539 ,  A61B2017/00544 ,  A61B2017/00557 ,  A61B2017/0256 ,  A61B2050/0065 ,  A61B2050/3015 ,  A61F2/28 ,  A61F2/2846 ,  A61F2/3601 ,  A61F2/389 ,  A61F2/44 ,  A61F2/441 ,  A61F2/4601 ,  A61F2/4611 ,  A61F2002/2817 ,  A61F2002/2825 ,  A61F2002/2828 ,  A61F2002/2832 ,  A61F2002/2835 ,  A61F2002/2853 ,  A61F2002/2871 ,  A61F2002/2892 ,  A61F2002/30113 ,  A61F2002/30115 ,  A61F2002/30125 ,  A61F2002/30131 ,  A61F2002/30133 ,  A61F2002/30204 ,  A61F2002/30225 ,  A61F2002/30228 ,  A61F2002/30242 ,  A61F2002/30247 ,  A61F2002/30253 ,  A61F2002/30285 ,  A61F2002/30288 ,  A61F2002/30308 ,  A61F2002/30311 ,  A61F2002/30313 ,  A61F2002/30448 ,  A61F2002/30462 ,  A61F2002/30464 ,  A61F2002/30581 ,  A61F2002/30586 ,  A61F2002/30599 ,  A61F2002/30677 ,  A61F2002/30686 ,  A61F2002/30909 ,  A61F2002/3611 ,  A61F2002/3625 ,  A61F2002/4062 ,  A61F2002/4217 ,  A61F2002/4602 ,  A61F2002/4627 ,  A61F2002/4635 ,  A61F2002/4636 ,  A61F2002/4685 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2230/0006 ,  A61F2230/0008 ,  A61F2230/0013 ,  A61F2230/0015 ,  A61F2230/0063 ,  A61F2230/0065 ,  A61F2230/0069 ,  A61F2230/0071 ,  A61F2230/0076 ,  A61F2250/0063 ,  A61F2310/00293 ,  A61F2310/00353 ,  A61F2310/0097 ,  A61M25/10 ,  A61M25/1002 ,  A61M25/1006 ,  A61M25/1009 ,  A61M25/1011 ,  A61M29/02 ,  A61M2025/1059 ,  A61M2025/1072 ,  A61M2210/02 ,  A61M2210/1003

摘要： A balloon (109) for use in compressing cancellous bone and marrow (also known as medullary bone or trabecular bone). The balloon (109) comprises an inflatable balloon body for insertion into said bone. The body has a shape and size to compress at least a portion of the cancellous bone to form a cavity in the cancellous bone and/or to restore the original position of the outer cortical bone, if fractured or collapsed. The balloon desirably incorporates restraints (117) which inhibit the balloon from applying excessive pressure to various regions of the cortical bone. The wall or walls of the balloon are such that proper inflation of the balloon body is achieved to provide for optimum compression of the bone marrow. The balloon can be inserted quickly into a bone. The balloon can be made to have a suction catheter. The balloon can be used to form and/or enlarge a cavity or passage in a bone, especially in, but not limited to, vertebral bodies. Various additional embodiments facilitate directionally biasing the inflation of the balloon.

公开(公告)号：EP1330270A2

公开(公告)日：2003-07-30

申请号：EP01991919.0

申请日：2001-11-02

申请人： Control Delivery Systems, Inc.

发明人： WATSON, David, A. ,  SMITH, Thomas, J. ,  LAPORTE, Richard ,  GUO, Hong ,  CHEN, Jianbing ,  ASHTON, Paul ,  SMITH, James, A.

IPC分类号： A61L2/00

CPC分类号： A61K9/0024 ,  A61B17/0642 ,  A61B17/1615 ,  A61B17/80 ,  A61B17/82 ,  A61B17/8615 ,  A61B17/8877 ,  A61B17/8886 ,  A61B2017/00004 ,  A61B2017/00429 ,  A61B2017/00955 ,  A61B2017/0647 ,  A61B2017/0648 ,  A61F2/30744 ,  A61F2002/30673 ,  A61F2002/30677 ,  A61L31/16 ,  A61L2300/222 ,  A61L2300/416 ,  A61L2300/602 ,  A61M31/002 ,  A61M2210/02

摘要： An implantable drug delivery system is provided including a mechanical member attachable to a portion of a body, a first chamber having an opening configured to receive a sustained release device, a sustained release device, and a removably attachable retainer for retaining the sustained release device in the first chamber. A method for administering a drug to a joint is provided including the steps of positioning a mechanical member in or adjacent a bone, the mechanical member configured to hold a sustained release drug delivery device at a substantially controlled rate. Also provided is a sustained release device intraarticularly implantable into a joint to deliver a therapeutically effective compound within a synovial capsule of the joint such that, in one aspect, the synovial fluid concentration of the compound is greater than the plasma concentration of the compound during the prolonged lifetime of the device, thereby eliminating unwanted systemic side effects and the need for frequent and repeated administrations.

公开(公告)号：EP1308134A3

公开(公告)日：2003-07-09

申请号：EP02024098.2

申请日：2002-10-29

申请人： Advanced Medical Technologies AG ,  Fürderer, Sebastian, Dr.

发明人： Fürderer, Sebastian

IPC分类号： A61B17/70 ,  A61M25/10

CPC分类号： A61B17/7097 ,  A61B17/8858 ,  A61B2017/00539 ,  A61B2017/00557 ,  A61B2017/0256 ,  A61M25/10 ,  A61M2025/1004 ,  A61M2210/02

摘要： Die Erfindung betrifft eine Vorrichtung zum Aufrichten und Stabilisieren der Wirbelsäule, insbesondere zur Stabilisierung gebrochener Wirbel. Erfindungsgemäß ist ein durch Innendruck plastisch aufweitbares Stützimplantat vorgesehen, das z.B. im Innern eines unter Kompression frakturierten Wirbelkörpers oder zwischen benachbarten Wirbelkörpern angeordnet werden kann. Vorzugsweise ist ein durch ein Druckfluid beaufschlagbarer, im Innern des Stützimplantats angeordneter Druckballon zur Erzeugung des Innendrucks vorgesehen.

公开(公告)号：EP0741547A1

公开(公告)日：1996-11-13

申请号：EP95908122.0

申请日：1995-01-24

申请人： Reiley, Mark, A. ,  Scholten, Arie ,  Talmadge, Karen

发明人： Reiley, Mark, A. ,  Scholten, Arie ,  Talmadge, Karen

IPC分类号： A61B ,  A61B17 ,  A61B10 ,  A61F2 ,  A61L27 ,  A61M25 ,  A61M37 ,  A61B19

CPC分类号： A61B10/025 ,  A61B17/00234 ,  A61B17/025 ,  A61B17/7258 ,  A61B17/742 ,  A61B17/744 ,  A61B17/8855 ,  A61B50/33 ,  A61B90/39 ,  A61B90/94 ,  A61B2010/0258 ,  A61B2017/00539 ,  A61B2017/00544 ,  A61B2017/00557 ,  A61B2017/0256 ,  A61B2050/0065 ,  A61B2050/3015 ,  A61F2/28 ,  A61F2/2846 ,  A61F2/3601 ,  A61F2/389 ,  A61F2/44 ,  A61F2/441 ,  A61F2/4601 ,  A61F2/4611 ,  A61F2002/2817 ,  A61F2002/2825 ,  A61F2002/2828 ,  A61F2002/2832 ,  A61F2002/2835 ,  A61F2002/2853 ,  A61F2002/2871 ,  A61F2002/2892 ,  A61F2002/30113 ,  A61F2002/30115 ,  A61F2002/30125 ,  A61F2002/30131 ,  A61F2002/30133 ,  A61F2002/30204 ,  A61F2002/30225 ,  A61F2002/30228 ,  A61F2002/30242 ,  A61F2002/30247 ,  A61F2002/30253 ,  A61F2002/30285 ,  A61F2002/30288 ,  A61F2002/30308 ,  A61F2002/30311 ,  A61F2002/30313 ,  A61F2002/30448 ,  A61F2002/30462 ,  A61F2002/30464 ,  A61F2002/30581 ,  A61F2002/30586 ,  A61F2002/30599 ,  A61F2002/30677 ,  A61F2002/30686 ,  A61F2002/30909 ,  A61F2002/3611 ,  A61F2002/3625 ,  A61F2002/4062 ,  A61F2002/4217 ,  A61F2002/4602 ,  A61F2002/4635 ,  A61F2002/4636 ,  A61F2002/4685 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2230/0006 ,  A61F2230/0008 ,  A61F2230/0013 ,  A61F2230/0015 ,  A61F2230/0063 ,  A61F2230/0065 ,  A61F2230/0069 ,  A61F2230/0071 ,  A61F2230/0076 ,  A61F2250/0063 ,  A61F2310/00293 ,  A61F2310/00353 ,  A61F2310/0097 ,  A61M25/10 ,  A61M25/1002 ,  A61M25/1011 ,  A61M2025/105 ,  A61M2025/1072 ,  A61M2210/02 ,  A61M2210/1003

摘要： A balloon (10) for use in compressing cancellous bone and marrow (also known as medullary bone and trabecular bone) against the inner cortex of bones whether the bones are fractured or not. The balloon comprises an inflatable, non-expandable balloon body (12, 14) for insertion into said bone. The body has a shape and size to compress at least a portion of the cancellous bone to form a cavity in the cancellous bone and to restore the original position of the outer cortical bone, if fractured or collapsed. The balloon is prevented from applying excessive pressure to the outer cortical bone. The wall or walls of the balloon are such that proper inflation of the balloon body is achieved to provide for optimun compression of all of the bone marrow. The balloon is folded so that it can be easily inserted into a bone. The balloon can be made to have a suction catheter (16). The main purpose of the balloon is the forming or enlarging of a cavity or passage in a bone, especially in, but not limited to, vertebral bodies.

公开(公告)号：EP0363873A2

公开(公告)日：1990-04-18

申请号：EP89118728.8

申请日：1989-10-09

申请人： CO PHARMA CORPORATION S.r.l.

发明人： Andreussi, Luciano

IPC分类号： A61M1/00

CPC分类号： A61M39/0247 ,  A61M25/02 ,  A61M27/006 ,  A61M2039/025 ,  A61M2039/0273 ,  A61M2039/0276 ,  A61M2039/0291 ,  A61M2210/02 ,  A61M2210/0687 ,  A61M2210/0693 ,  A61M2230/005

摘要： A device for fastening a catheter to an osteofibrous wall, for example, to a cranial theca (6) for draining cerebro spinal fluid or any other serous fluid therefrom, particularly for use in pediatric neurosurgery, comprising a tubular body (1) arranged to receive a catheter (10), at least one transverse end foot (2) for insertion into an aperture (7) in the cranial theca (6), and a locking element (4) which can be fitted in opposite relationship with the foot (2) so as to bear on the outer surface of the cranial theca (6) in close liquid-tight contact therewith.

摘要翻译： 一种用于在骨纤维壁紧固导管，例如，颅骨卵泡膜（6）用于排出脑脊髓液或者任何其他浆液有从，特别是用于儿科神经外科应用，包括管状体装置（1）被布置为接收 导管（10），至少一个横向端脚（2），用于插入在所述颅卵泡膜（6），并且其可以安装在与脚相对关系的锁定元件（4）（孔径（7）2 ），以便颅卵泡膜的外表面上承担（6）关闭与有液密接触。

公开(公告)号：EP0319541A1

公开(公告)日：1989-06-14

申请号：EP87905462.0

申请日：1987-08-25

申请人： ROYAL POSTGRADUATE MEDICAL SCHOOL

发明人： BEVERLY, Michael

IPC分类号： A61M27 ,  A61M37 ,  A61B19

CPC分类号： A61M27/002 ,  A61B90/39 ,  A61M27/00 ,  A61M2210/02

摘要： Un drain osseux implantable (1), destiné à réduire la pression intraosseuse, est formé d'un matériau bio-compatible et comporte une surface externe conçue de façon à empêcher ou à limiter le mouvement du drain hors de sa position après l'implantation (par exemple à l'aide de parties en saillies souples ou déformables (5)), et/ou on peut prévoir d'autres moyens pour maintenir le drain osseux dans la position d'implantation choisie. Plusieurs ouvertures de drainage (2) peuvent être disposées sur la longueur du drain. Celui-ci peut être utilisé dans le traitement de douleurs osseuses qui se manifestent dans le cadre de troubles orthopédiques notamment arthritiques et peut également être utilisé pour retarder le développement d'affections dégénératives.

公开(公告)号：EP2851096B1

公开(公告)日：2018-11-28

申请号：EP12877065.8

申请日：2012-06-08

申请人： Sewon Cellontech Co., Ltd

发明人： YEO, Se Ken ,  CHANG, Cheong Ho ,  YOO, Ji Chul ,  SUH, Dong Sam ,  LEE, Jun Keun ,  WOO, Sang Hun

IPC分类号： A61L27/24 ,  A61L27/20 ,  A61F2/30 ,  A61L27/26 ,  A61K38/39 ,  A61M5/31

CPC分类号： A61K38/39 ,  A61K31/728 ,  A61L27/26 ,  A61L2400/06 ,  A61L2430/06 ,  A61M5/31 ,  A61M2210/02 ,  C08L5/08 ,  C08L89/06

摘要： The present invention relates to a composition for repairing cartilage tissue, to a method for producing same, and to the use thereof. The present invention provides a composition for repairing cartilage tissue, which is obtained by mixing collagen and hyaluronic acid using a two-way syringe or a mixer, wherein the collagen has a diluted concentration of 5-60 mg/mL excepting water or a physiological phosphate buffer solution, and the hyaluronic acid has a diluted concentration of 5-20 mg/mL excepting water or a physiological phosphate buffer solution.