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11.
公开(公告)号:EP4414451A2
公开(公告)日:2024-08-14
申请号:EP24169292.0
申请日:2014-04-25
申请人: Genomatica, Inc.
发明人: PHARKYA, Priti , BURGARD, Anthony P. , VAN DIEN, Stephen J. , OSTERHOUT, Robin E. , BURK, Mark J. , TRAWICK, John D. , KUCHINSKAS, Michael P. , STEER, Brian , ANDRAE, Stefan , SHAH, Amit
IPC分类号: C12N15/00
CPC分类号: C12P7/24 , C12P7/62 , C12P17/04 , C12N15/52 , C12P7/42 , C12P13/005 , C12P7/18 , C12P13/001 , C07D307/33 , C12N9/13 , C12Y208/03
摘要: The invention provides non-naturally occurring microbial organisms having a 4-hydroxybutyrate, gamma-butyrolactone, 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-CoA and/or putrescine pathway and being capable of producing 4-hydroxybutyrate, wherein the microbial organism comprises one or more genetic modifications. The invention additionally provides methods of producing 4-hydroxybutyrate, gamma-butyrolactone, 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-CoA and/or putrescine or related products using the microbial organisms.
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公开(公告)号:EP3661951B1
公开(公告)日:2024-08-07
申请号:EP18759402.3
申请日:2018-07-30
IPC分类号: C12P23/00 , C12N9/02 , C07K14/415 , C12N15/82 , C12N15/52
CPC分类号: C07K14/415 , C12P23/00 , C12N9/0008 , C12Y102/01003 , C12N15/52 , C12N15/8243
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13.
公开(公告)号:EP4403629A1
公开(公告)日:2024-07-24
申请号:EP22876657.2
申请日:2022-08-05
发明人: KIM, Heeyeong , KIM, Kyungrim , CHOI, Woosung , CHEONG, Ki Yong
摘要: The present disclosure relates to a novel acetohydroxy acid synthase (AHAS) variant improving L-isoleucine producing ability, a microorganism including the same, and a method of producing L-isoleucine using the microorganism.
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公开(公告)号:EP4397759A2
公开(公告)日:2024-07-10
申请号:EP24165188.4
申请日:2013-10-23
申请人: Toolgen Incorporated
发明人: KIM, Jin-Soo , CHO, Seung Woo , KIM, Sojung
IPC分类号: C12N15/11
CPC分类号: C12N2310/53120130101 , C12N15/8216 , C12Y301/21 , C12N9/22 , C12N15/102 , C12N15/63 , C12N9/16 , C12N15/52 , C12N15/111 , C12N2310/2020170501
摘要: The present invention relates to targeted genome editing in eukaryotic cells or organisms. More particularly, the present invention relates to a composition for cleaving a target DNA in eukaryotic cells or organisms comprising a guide RNA specific for the target DNA and Cas9 protein, and uses thereof.
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公开(公告)号:EP4396209A1
公开(公告)日:2024-07-10
申请号:EP22865847.2
申请日:2022-09-02
申请人: Amyris, Inc.
CPC分类号: C07K14/39 , C12P19/04 , C12N15/81 , C12N15/52 , C12Y101/01021 , C12Y101/01 , C12N9/0004 , C12N9/1048 , C12N9/22 , C07K14/395 , C12R2001/86520210501 , C12Y204/01056 , C12Y204/01 , C12R2001/64520210501 , C12N9/0006 , C12Y204/01038 , C12N9/1241 , C12Y207/07023 , C12Y402/01047 , C12N9/88 , C12N9/1051 , C12Y204/01069 , C12Y101/01271 , C12P19/00 , C12P19/18
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公开(公告)号:EP4384623A1
公开(公告)日:2024-06-19
申请号:EP22852154.8
申请日:2022-08-02
发明人: SHAO, Wei , CHEN, Jinggong , XU, Ying , LONG, Yu , ZHANG, Jing , LIU, Xingxing , LIU, Jinrong , WU, Wei , HAO, Weidong , CHEN, Jianxin
CPC分类号: C12N15/67 , C12N15/52 , C12N9/93 , C12Y603/01002
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19.
公开(公告)号:EP4381056A1
公开(公告)日:2024-06-12
申请号:EP21763022.7
申请日:2021-08-05
申请人: Wacker Chemie AG
发明人: MARTIN, Julia , BORNHÖVD, Carsten
CPC分类号: C12N9/1051 , C12P19/18 , C12Y204/01069 , C12N15/52 , C12P19/00
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