公开(公告)号：EP1848983A1

公开(公告)日：2007-10-31

申请号：EP05736243.6

申请日：2005-02-15

Applicant: Tata Institute of Fundamental Research

Inventor： MAITI, Sudipta, Tata Institute of Fundamental ,  KAUSHALYA, Sanjeev K., Tata Institute of Fundamen. ,  GARAI, Kanchan, Tata Institute of Fundamental ,  BALAJI, Jayaprakash, Tata Institute of Fundamental

IPC: G01N21/64 ,  G02B21/00 ,  G01J3/457

CPC classification number: G01N21/6458 ,  G01J1/46 ,  G01N2021/1738 ,  G01N2021/6421 ,  G01N2021/6484 ,  G01N2201/0221

Abstract: This invention relates to a confocal fluorescence correlation microscope with real-time alignment read out. With this instrument it is possible to do confocal imaging together with the particle size determination at a chosen location in the specimen. In particular, this invention relates to a detector module with a fixed aperture and detection electronics that can be conveniently connected to an existing confocal or multiphoton microscope, near the base of the objective lens of the microscope. This detector splits a part of the signal and uses it to generate a spot on the confocal image. This shows the spot where an FCS measurement can be carried out, and the same signal can then be used to perform a fluorescence correlation measurement after parking the excitation beam of the confocal to that spot. No alignment step is necessary for obtaining the measurement.

公开(公告)号：EP1367383B1

公开(公告)日：2007-09-19

申请号：EP02012155.4

申请日：2002-06-01

Applicant: Siemens Schweiz AG

Inventor： Forster, Martin, Dr. ,  Pleisch, Rolf

IPC: G01N21/35 ,  G01J3/457

CPC classification number: G01J3/457 ,  G01N21/3504

公开(公告)号：EP1218704A4

公开(公告)日：2007-03-21

申请号：EP00910174

申请日：2000-02-14

Applicant: PLAIN SIGHT SYSTEMS INC

Inventor： FATELEY WILLIAM G

IPC: G01J3/28 ,  G01J3/02 ,  G01J3/06 ,  G01J3/10 ,  G01J3/18 ,  G01J3/32 ,  G01J3/457 ,  G01N21/39 ,  G02B26/08 ,  G02B27/10

CPC classification number: G01J3/02 ,  G01J3/0218 ,  G01J3/0229 ,  G01J3/027 ,  G01J3/06 ,  G01J3/10 ,  G01J3/18 ,  G01J3/2823 ,  G01J3/2889 ,  G01J3/32 ,  G01J3/457 ,  G01J2003/2866 ,  G01N21/39 ,  G01N2021/393 ,  G01N2021/6463 ,  G02B26/0841 ,  G02B27/1086

Abstract: A spectrometer (10) includes a two-dimensional array of modulatable microm-irrors (18), a detector (20), and an analyzer (22). The micro-mirrors are positioned for receiving individual radiation components forming a part of a radiation source. The micro-mirrors are modulated at different modulation rates in order to reflect individual radiation components at known and different modulation rates. The micro-mirrors combine a number of the reflected individual radiation components and reflect them to the detector. The detector receives the combined radiation components and creates an output signal. The analyzer is coupled to the detector to receive the output signal and to analyze at least some of the individual radiation components making up the combined reflection. By using a micro-mirror array that modulates the radiation components at different rates, all of the radiations components can be focused onto a single detector to maximize the signal-to-noise ratio of the detector.

公开(公告)号：EP0935679A4

公开(公告)日：2001-01-24

申请号：EP97945247

申请日：1997-09-19

Applicant: APPLIED SPECTRAL IMAGING LTD

Inventor： CABIB DARIO ,  BUCKWALD ROBERT A ,  BEN-YOSEF NISSIM

IPC: C12Q1/68 ,  G01J3/02 ,  G01J3/12 ,  G01J3/26 ,  G01J3/28 ,  G01J3/44 ,  G01J3/453 ,  G01J3/457 ,  G01N21/64 ,  G01N33/50 ,  G01N33/569 ,  G06K9/00 ,  G06K9/76 ,  G02B21/00 ,  G06T5/00

CPC classification number: C12Q1/6816 ,  C12Q1/6841 ,  C12Q1/6883 ,  G01J3/02 ,  G01J3/12 ,  G01J3/1256 ,  G01J3/26 ,  G01J3/2823 ,  G01J3/4406 ,  G01J3/453 ,  G01J3/457 ,  G01J2003/2866 ,  G01N21/6428 ,  G01N21/6458 ,  G01N33/5005 ,  G01N33/56966 ,  G01N2021/6423 ,  G01N2021/6441 ,  G01N2021/6471 ,  G06K9/00127 ,  G06K9/76

Abstract: A method and hardware for chromosome classification by decorrelation statistical analysis to provide color (spectral) karyotypes and to detect chromosomal aberrations.

公开(公告)号：EP0945718A1

公开(公告)日：1999-09-29

申请号：EP98105160.0

申请日：1998-03-21

Applicant: Evotec BioSystems AG

Inventor： Palo, Kaupo

IPC: G01J3/457

CPC classification number: G01N21/6408 ,  G01J3/4406 ,  G01J3/457 ,  G01J2003/2866 ,  G01N15/14

Abstract: A method for characterizing samples having units, by monitoring fluctuating intensities of radiation emitted, scattered and/or reflected by said units in at least one measurement volume, the monitoring being performed by at least one detection means, said method comprising the steps of:

a) measuring in a repetitive mode a length of time intervals between photon counts,
b) determining a function of the length of said time intervals,
c) determining a function of at least one specific physical property of said units on basis of said function of the length of time intervals.

Abstract translation: 一种用于表征具有单位的样品，通过监测发射的辐射，散射和/或由所述单元中的至少一个测量体积的反射的波动强度的方法，所述监测由至少一个检测装置执行，所述方法包括以下步骤：a 以重复的方式）测定光子计数之间的时间间隔的长度，b）中确定的采矿所述时间间隔的长度的函数，c）中确定的采矿的所述单元的至少一个特定物理性质的对的所述功能的基础函数 时间间隔的长度。

公开(公告)号：EP4447797A1

公开(公告)日：2024-10-23

申请号：EP22908541.0

申请日：2022-12-19

Applicant: University Of South Florida

Inventor： PARTHASARATHY, Ashwin ,  MOKA, Sadhu ,  SAFI, Abdul Mohaimen

IPC: A61B5/026 ,  G01J3/457 ,  G01N21/47

公开(公告)号：EP4194840A1

公开(公告)日：2023-06-14

申请号：EP21874845.7

申请日：2021-07-05

Applicant: Hamamatsu Photonics K.K.

Inventor： WATANABE, Koyo ,  TAKAHASHI, Hisanari ,  SHIGEMATSU, Kyohei ,  INOUE, Takashi

IPC: G01N21/41 ,  G01B11/02 ,  G01J3/457 ,  G01J11/00 ,  G01M11/02 ,  G01N21/35 ,  G02F1/01 ,  G02F1/37

Abstract: A dispersion measurement apparatus 1A includes a pulse forming unit 3, an imaging unit 5, and an operation unit 6. The pulse forming unit 3 forms a light pulse train Pb including a plurality of light pulses having time differences and center wavelengths different from each other from a light pulse Pa output from a pulsed laser light source 2. The imaging unit 5 includes an image sensor 51 capable of performing imaging at an imaging interval shorter than a minimum peak interval of the light pulse train Pb, and images a light pulse train Pc output from the pulse forming unit 3 and then passed through a measurement object B to generate imaging data. The operation unit 6 receives the imaging data, detects a temporal waveform of the light pulse train Pc for each pixel of the image sensor 51, and estimates a wavelength dispersion amount of the measurement object B for each pixel of the image sensor 51 based on a feature value of the temporal waveform. Thus, a dispersion measurement apparatus and a dispersion measurement method capable of measuring a wavelength dispersion by a simple configuration are realized.

公开(公告)号：EP3877734A2

公开(公告)日：2021-09-15

申请号：EP19882272.8

申请日：2019-11-08

Applicant: Seti Institute

Inventor： SPARKS, William, B.

IPC: G01J3/42 ,  G01J3/427 ,  G01J3/433 ,  G01J3/44 ,  G01J3/443 ,  G01J3/447 ,  G01J3/45 ,  G01J3/457

公开(公告)号：EP2529152B1

公开(公告)日：2017-11-15

申请号：EP10844948.9

申请日：2010-12-30

Applicant: I.S.S (USA) Inc.

Inventor： GRATTON, Enrico ,  D'AMICO, Enrico

IPC: G01N21/64 ,  G01J3/44 ,  G01J3/457

CPC classification number: G01N21/6408 ,  G01J3/4406 ,  G01J3/457 ,  G01N21/6458 ,  G01N2021/6423 ,  G01N2021/6441

公开(公告)号：EP2989442A4

公开(公告)日：2016-12-28

申请号：EP13889199

申请日：2013-07-09

Applicant: HALLIBURTON ENERGY SERVICES INC

Inventor： GAO LI ,  PELLETIER MICHAEL T ,  PERKINS DAVID L ,  SKINNER NEAL GREGORY

IPC: G01N21/27 ,  E21B49/08 ,  G01J3/02 ,  G01J3/28 ,  G01J3/457 ,  G01J5/08 ,  G02B5/20 ,  H01Q15/00

CPC classification number: G01N21/255 ,  E21B49/08 ,  G01J3/0205 ,  G01J3/28 ,  G01J3/457 ,  G01N21/27 ,  G01N33/24 ,  G01N2201/068 ,  G02B5/20 ,  G02B5/201 ,  G02B5/204