-
公开(公告)号：EP2852610B1
公开(公告)日：2018-07-11
申请号：EP13725617.8
申请日：2013-05-23
申请人： Glykos Finland Oy
发明人： NATUNEN, Jari , WESTERHOLM-PARVINEN, Ann , SALO, Hanna , JOENSUU, Jussi , VISKARI, Heli , LANDOWSKI, Christopher , HUUSKONEN, Anne , KANERVA, Anne , HÄNNINEN, Anna-Liisa , SALOVUORI, Noora , PENTTILÄ, Merja , SAARINEN, Juhani , SALOHEIMO, Markku
IPC分类号： C07K14/435 , C12P21/00 , C12N9/10
CPC分类号： C12P21/005 , C07K14/43545 , C07K16/00 , C07K2319/01 , C12N9/0006 , C12N9/1051 , C12N9/58 , C12N9/88 , C12N15/52 , C12N15/80
摘要： Described herein are compositions including filamentous fungal cells, such as Trichoderma fungal cells, having reduced protease activity and expressing fucosylation pathway. Further described herein are methods for producing a glycoprotein having fucosylated N-glycan, using genetically modified filamentous fungal cells, for example, Trichoderma fungal cells, as the expression system.
-
公开(公告)号：EP2431743B1
公开(公告)日：2018-05-30
申请号：EP11189389.7
申请日：2006-07-20
申请人： Glykos Finland Oy
发明人： Satomaa, Tero , Natunen, Jari , Heiskanen, Annamari , Olonen, Anne , Saarinen, Juhani , Salovuori, Noora , Helin, Jari
IPC分类号： G01N33/574 , A61K31/715
CPC分类号： C07K16/44 , C07K2317/21 , C07K2317/24 , C07K2317/76 , C12Q1/34 , G01N33/574 , G01N33/57488 , G01N33/57492 , G01N2400/38 , Y10T436/143333
摘要： The present invention describes glycans, which are specifically expressed by certain cancer cells, tumours and other malignant tissues. The present invention describes methods to detect cancer specific glycans as well as methods for the production of reagents binding to said glycans. The invention is also directed to the use of said glycans and reagents binding to them for the diagnostics of cancer and malignancies. Furthermore, the invention is directed to the use of said glycans and reagents binding to them for the treatment of cancer and malignancies. Moreover, the present invention comprises efficient methods to differentiate between malignant and benign tumors by analyzing glycan structures.
-
公开(公告)号：EP2167674B1
公开(公告)日：2018-04-18
申请号：EP08775485.9
申请日：2008-06-13
申请人： Glykos Finland Oy , Hankkija Oy
IPC分类号： A23K20/163 , A23L29/30 , A61K31/715 , A61K36/064 , A61P1/00 , C07H1/08 , C12P19/04
CPC分类号： C12P19/04 , A23K20/163 , A23L5/00 , A23L29/30 , A23L31/10 , A61K36/064 , C07H1/08
摘要： The present invention is directed to a novel saccharide composition isolated from a yeast culture. The invention is also directed to yeast cell based saccharide composition with increased water-solubility. The saccharide compositions disclosed in the invention can be used as nutritional or pharmaceutical additives or as part of nutritional or pharmaceutical composition in order to promote the health of an animal or human subject to which said composition is administered. The invention is also directed to methods of producing said saccharide compositions.
-
4.发明授权PRODUCTION OF A SACCHARIDE COMPOSITION COMPRISING GLUCANS AND MANNANS BY ALKALINE AND ACID HYDROLYSIS OF YEAST CELLS 有权MAKING与葡聚糖和甘露聚糖碱和酵母细胞酸酸水解糖组分
公开(公告)号：EP2370475B1
公开(公告)日：2017-02-15
申请号：EP09832997.2
申请日：2009-12-18
申请人： Glykos Finland Oy
CPC分类号： C12P19/04 , A23K20/163 , A23L2/52 , A23L5/00 , A23L29/30 , A23L31/10 , A23L33/10 , A23L33/14 , C08B37/0003 , C08B37/0087
摘要： The present invention is directed to a method of production of an immunostimulatory composition having a saccharide fraction, the method including the steps of hydrolyzes of yeast cells and recovering the soluble fraction. The saccharide fraction having composition thus obtained may be incorporated as a food or beverage component or be used as a pharmaceutical for treatment of specific conditions.
摘要翻译： 本发明涉及生产具有糖类成分，包括酵母细胞的水解步骤的方法，回收可溶性部分的免疫刺激组合物的方法。 由此获得的糖类成分具有组合物可作为食物或饮料组分或用作用于治疗特定病症的药物。
-
公开(公告)号：EP2986713A1
公开(公告)日：2016-02-24
申请号：EP14721912.5
申请日：2014-04-16
申请人： Glykos Finland Oy
IPC分类号： C12N5/074
CPC分类号： C12N5/0696 , C12N2506/1307 , C12N2510/00 , C12N2533/50 , G01N33/56966
摘要： The invention relates to a method for generating induced pluripotent stem cells, wherein the method comprises: step a) of inducing non- pluripotent cells to produce a mixture comprising induced pluripotent stem cells and non-pluripotent cells; step b) of contacting the mixture comprising induced pluripotent stem cells and non- pluripotent cells obtainable from step a) with a binding agent, wherein the binding agent is capable of binding an epitope consisting of the non-reducing terminal saccharide structure according to formula (Fucα1-2)
a Galβ1-3HexNAcβ, whereina= 0 or 1 and Hex is either Glc or Gal; and step c) of selecting an induced pluripotent stem cell bound by the binding agent.-
公开(公告)号：EP2315828B1
公开(公告)日：2015-07-01
申请号：EP09784152.2
申请日：2009-07-13
申请人： Glykos Finland Oy
发明人： IMPOLA, Ulla , TIITTANEN, Minna , MIKKOLA, Milla , PARTANEN, Jukka , NATUNEN, Jari , SATOMAA, Tero , SAARINEN, Juhani
IPC分类号： C12N5/0735 , C07K14/47
CPC分类号： C12N15/873 , C12N5/0606 , C12N5/0696 , C12N2500/90 , C12N2501/115 , C12N2533/50
-
公开(公告)号：EP1419393B1
公开(公告)日：2014-08-13
申请号：EP02753102.9
申请日：2002-08-20
申请人： Glykos Finland Oy
IPC分类号： G01N33/574 , C07H5/06 , A61K39/00 , A61P35/00
CPC分类号： A61K39/39558 , A61K38/1709 , A61K38/45 , A61K39/00 , A61K47/549 , A61K47/6851 , A61K2039/505 , C07H3/06 , C07K16/18 , C12Y204/00 , G01N33/57469 , G01N33/57492
摘要： The present invention describes oligosaccharide sequences, which are specifically expressed by human tumors. The present invention is related to a method of determining an oligosaccharide sequence, which comprises a tumor specific terminal N-acetylglucosamine residue, in a biological sample, the presence of said sequence in said sample being an indication of the presence of cancer. The present invention provides antigenic substances comprising said oligosaccharide sequences in a polyvalent form and it further provides diagnostic agents, pharmaceutical compositions and cancer vaccines comprising said oligosaccharide sequences or substances binding to said oligosaccharide sequences. The present invention is also related to methods for the treatment of cancer.
-
公开(公告)号：EP1891437B1
公开(公告)日：2014-04-02
申请号：EP06764482.3
申请日：2006-06-06
申请人： Glykos Finland Oy
发明人： JAATINEN, Taina , ANDERSON, Heidi , PARTANEN, Jukka , LAINE, Jarmo , SATOMAA, Tero , NATUNEN, Jari , BLOMQVIST, Maria
IPC分类号： G01N33/50 , G01N33/567 , G01N33/577 , C12Q1/68 , C07H3/06
CPC分类号： G01N33/5308 , G01N33/5002 , G01N33/56966
-
公开(公告)号：EP1913385B1
公开(公告)日：2013-08-21
申请号：EP06778525.3
申请日：2006-07-11
申请人： Glykos Finland Oy
发明人： SATOMAA, Tero , NATUNEN, Jari , HEISKANEN, Annamari , BLOMQVIST, Maria , OLONEN, Anne , SAARINEN, Juhani
IPC分类号： G01N33/50 , G01N33/543 , G01N33/574 , C07H5/06 , C08B37/00
CPC分类号： G01N33/5308 , C08B37/00 , G01N2400/12 , G01N2400/38
-
公开(公告)号：EP2322209A3
公开(公告)日：2012-02-01
申请号：EP10184228.4
申请日：2003-08-20
申请人： Glykos Finland Oy
CPC分类号： A61K39/39558 , A61K38/1709 , A61K38/45 , A61K39/00 , A61K47/549 , A61K47/6851 , A61K2039/505 , C07H3/06 , C07K16/18 , C12Y204/00 , G01N33/57469 , G01N33/57492
摘要： The present invention describes oligosaccharide sequences, which are specifically expressed by human tumors. The present invention is related to a method of determining an oligosaccharide sequence, which comprises a tumor specific terminal N-acetylglucosamine residue, in a biological sample, the presence of said sequence in said sample being an indication of the presence of cancer. The present invention provides antigenic substances comprising said oligosaccharide sequences in a polyvalent form and it further provides diagnostic agents, pharmaceutical compositions and cancer vaccines comprising said oligosaccharide sequences or substances binding to said oligosaccharide sequences. The present invention is also related to methods for the treatment of cancer.
-
-
-
-
-
-
-
-
-
搜索结果
80 条记录 (耗时 0.037 秒)
