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公开(公告)号：EP4352264A1
公开(公告)日：2024-04-17
申请号：EP22730597.6
申请日：2022-06-09
申请人： University College London , Università Degli Studi Di Trento , Cornell University , The University of British Columbia
发明人： ATTARD, Gerhardt , DEMICHELIS, Francesca , ROMANEL, Alessandro , ORLANDO, Francesco , RUBIN, Mark , BELTRAN, Himisha , WYATT, Alexander
IPC分类号： C12Q1/6886
CPC分类号： C12Q1/6886 , C12Q2600/11220130101 , C12Q2600/11820130101
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2.发明公开
公开(公告)号：EP3630823A1
公开(公告)日：2020-04-08
申请号：EP18721728.6
申请日：2018-04-26
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公开(公告)号：EP3259237A1
公开(公告)日：2017-12-27
申请号：EP16704900.6
申请日：2016-02-10
IPC分类号： C03C17/245 , C23C16/40 , C23C16/448 , C23C14/18
CPC分类号： C23C16/40 , C03C17/245 , C03C17/3417 , C03C2217/214 , C03C2217/215 , C03C2217/216 , C03C2217/228 , C03C2217/70 , C03C2218/152 , C23C14/18 , C23C16/407 , C23C16/4486
摘要： A process for depositing an inorganic material on a substrate, the process comprising, providing a substrate having a surface, providing a precursor mixture comprising a metal sulfonate, and delivering the precursor mixture to the surface of the substrate, wherein the surface of the substrate is at a substrate temperature of above 450 °C and is sufficient to effect decomposition of the metal sulfonate. The inorganic material may include a metal or a metal oxide. The preferred metal sulfonate is metal triflate.
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公开(公告)号：EP3061416A1
公开(公告)日：2016-08-31
申请号：EP16150799.1
申请日：2001-04-12
发明人： BLUNN, Gordon , PERRY, John , NOORDEEN, Hilali , MESWANIA, Jay , COBB, Justin
IPC分类号： A61B17/72 , A61F2/36 , A61B17/66 , A61B17/80 , A61B17/86 , A61F2/30 , A61F2/38 , A61F2/44 , A61F2/48 , A61B17/00
CPC分类号： A61B17/7016 , A61B17/66 , A61B17/7216 , A61B17/80 , A61B17/86 , A61B2017/00137 , A61B2017/00831 , A61F2/30767 , A61F2/3607 , A61F2/3676 , A61F2/38 , A61F2/44 , A61F2002/30079 , A61F2002/30354 , A61F2002/30367 , A61F2002/30372 , A61F2002/30403 , A61F2002/30405 , A61F2002/30411 , A61F2002/30451 , A61F2002/30512 , A61F2002/30523 , A61F2002/30525 , A61F2002/30527 , A61F2002/3055 , A61F2002/30578 , A61F2002/30591 , A61F2002/30601 , A61F2002/3067 , A61F2002/30706 , A61F2002/30777 , A61F2002/30878 , A61F2002/3611 , A61F2002/3625 , A61F2002/48 , A61F2002/482 , A61F2210/009 , A61F2220/0025 , A61F2220/0033 , A61F2220/0058 , A61F2250/0002 , A61F2250/0082 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00796
摘要： A surgical distraction device is provided for applying extending or tensioning force non-invasively to a patient's skeleton or to an implant which comprises anchoring means for attaching first and second components of the device to a bone or to adjoining bones, said components being connected by a linkage of an extendible length, a magnet connected to the linkage via a reduction gearbox and actuating means located externally of the patient for generating a moving or varying electromagnetic field, thereby causing the magnet to rotate and the linkage to be extended.
摘要翻译： 提供了一种手术牵开装置，用于非侵入性地向患者的骨架或植入物施加伸展或张紧力，所述植入物包括用于将装置的第一和第二部件附接到骨骼或邻近骨骼的锚固装置，所述部件通过 可延伸长度的连接，通过减速齿轮箱连接到联动装置的磁体和位于患者外部的致动装置，用于产生移动或变化的电磁场，从而使磁体旋转并且连杆被延伸。
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公开(公告)号：EP1534330B1
公开(公告)日：2014-03-12
申请号：EP03793906.3
申请日：2003-09-05
CPC分类号： A61K39/04 , A61K39/39 , A61K2039/55594 , A61K2039/57 , Y02A50/466
摘要： An immune modulator composition and/or pharmaceutical composition comprising a whole cell of a bacterium from the genera Rhodococcus, Gordonia, Nocardia, Dietzia, Tsukamurella and Nocardioides, wherein said immune modulator composition in use modifies a cellular immune response.
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公开(公告)号：EP2590682A1
公开(公告)日：2013-05-15
申请号：EP11738467.7
申请日：2011-07-11
CPC分类号： A61K47/48046 , A61K9/0019 , A61K9/0092 , A61K9/08 , A61K38/00 , A61K47/48092 , A61K47/542 , A61K47/543 , A61K47/549
摘要： A composition comprises nanofibres for the delivery of a peptide across the blood brain barrier in a method of therapy of the human or animal body, wherein the nanofibres comprise a peptide conjugated to a lipophilic group. Further, a compound comprises a Dalargin or a derivative having one or more substituted, deleted or inserted aminoacyl units, and, conjugated to an aminoacyl group preferably via a side chain, a lipophilic group, optionally via a linker.
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7.发明授权USE OF THE INSULIN-LIKE-GROWTH FACTOR I SPLICE VARIANT MGF FOR THE PREVENTION OF MYOCARDIAL DAMAGE 有权使用胰岛素样生长因子我剪接的心肌损伤VARIANT MGF预防
公开(公告)号：EP1480669B1
公开(公告)日：2013-01-23
申请号：EP03737378.4
申请日：2003-02-06
CPC分类号： A61K38/18 , A61K31/7088 , A61K38/30
摘要： The invention relates to the use of a Mechano Growth Factor (MGF) polypeptide or a polynucleotide encoding an MGF polypeptide in the manufacture of a medicament for the prevention or limitation of myocardial damage in response to ischemia or mechanical overload of the heart by preventing or limiting apoptosis in the myocardium.
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8.发明公开INDAZOLE DERIVATIVES AND THEIR USE FOR BLOCKADING VOLTAGE DEPENDENT SODIUM CHANNELS 审中-公开吲唑和它们在电压依赖性钠通道的封锁
公开(公告)号：EP2483270A1
公开(公告)日：2012-08-08
申请号：EP10760746.7
申请日：2010-09-30
发明人： POSADA, Cristina, Garcia , SELWOOD, David , GARTHWAITE, John , BAKER, David , CLUTTERBUCK, Lisa
IPC分类号： C07D413/14 , C07D417/14 , A61K31/4245 , A61P25/00 , A61P23/00
CPC分类号： C07D413/14 , C07D417/14
摘要： The invention provides an indazole derivative of formula (1), or a pharmaceutically acceptable salt or N-oxide thereof, wherein R
1 , R
2 , R
3 and R
4 are as defined herein. The indazole derivatives are capable of blockading voltage dependent sodium channels and they are useful in the treatment or prevention of normal tension glaucoma, multiple sclerosis, a motorneurone disease, stroke, spinal cord injury, Alzheimer's disease, Parkinson's disease or pain.-
9.发明公开PROBE FOR DETECTING MAGNETIC PROPERTIES OF MATERIALS 有权Sonde zur Detektion von magnetischen Materialeigenschaften
公开(公告)号：EP2267471A1
公开(公告)日：2010-12-29
申请号：EP10180206.4
申请日：2006-04-28
IPC分类号： G01R33/035 , G01R33/12
CPC分类号： G01R33/1215
摘要： Apparatus for determining magnetic properties of materials comprises a portable probe 1, an equipment trolley 2 holding cryogenics and electronics and connecting cables 3.
The probe 1 comprises a drive coil 4 and a correction coil 5, the drive coil 4 being disposed symmetrically with respect to an inner second-order gradiometer sensor coil 8.
Electrical connectors in the form of 2-metre long Belden 1192A microphone cables 3 are used to connect the apparatus on the equipment trolley 2 to the drive coil 4, the correction coil 5 and the sensor coil 8.
The drive coil 4 is driven so as to generate a sinusoidally varying magnetic field.
The electronics comprise a flux-locked loop 9, a SQUID controller 10, a data acquisition module 11, which captures and processes the signals and a computer 12.
A liquid-nitrogen dewar 13 is supported on the equipment trolley 2 and houses a sensitive SQUID detector 14 and a transfer coil 15 made from copper.
Possible applications of the apparatus include an intra-operative tool for sentinel lymph node detection in the treatment of breast cancer, and a non-destructive evaluation tool for detecting voids and defects in aluminium and applications in the aeronautics industry.摘要翻译： 用于确定材料的磁特性的装置包括便携式探头1，容纳低温物质的电子设备和连接电缆3的设备手推车2.探针1包括驱动线圈4和校正线圈5，驱动线圈4相对于 内部二阶梯度传感器线圈8.以2米长的Belden 1192A麦克风电缆3的形式的电连接器用于将设备手推车2上的装置连接到驱动线圈4，校正线圈5和传感器线圈 驱动线圈4被驱动以产生正弦变化的磁场。 电子装置包括一个磁通锁定环9，一个SQUID控制器10，一个捕捉和处理这些信号的数据采集模块11以及一台计算机12.液氮杜瓦13被支撑在设备手推车2上，并容纳敏感的SQUID 检测器14和由铜制成的传输线圈15。 该装置的可能应用包括用于乳腺癌治疗中的前哨淋巴结检测的手术工具，以及用于检测铝中的空隙和缺陷以及在航空工业中的应用的非破坏性评估工具。
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公开(公告)号：EP2170429A2
公开(公告)日：2010-04-07
申请号：EP08762515.8
申请日：2008-06-25
发明人： SELDEN, Clare , HODGSON, Humphrey , COWARD, Sam
CPC分类号： A01N1/0247 , A01N1/02 , A01N1/0257 , A61F2/022 , A61M1/3472 , A61M1/3489 , A61M1/3689 , C12M21/08 , C12M23/06 , C12M25/16 , C12M29/04 , C12M41/24 , C12N5/0671 , C12N2511/00 , C12N2533/12 , C12N2533/74
摘要： The present invention relates to the field of extracorporeal liver perfusion and, more particularly, to a method of proliferating human hepatocyte derived cells. It comprises; a) Seeding cells into a matrix forming agent; b) Pre-culturing the matrix encapsulated cells so that they form cohesive spheroids and; c) Growing them to performance competence.
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