公开(公告)号：EP3134424A4

公开(公告)日：2018-03-14

申请号：EP15782933

申请日：2015-04-21

申请人： LAKEVIEW NUTRITION LLC

发明人： HUANG DEJIAN ,  OU BOXIN ,  GALVIN JIM ,  BYRNE EAMONN

IPC分类号： C07K1/14 ,  B01D11/00 ,  C07H1/08 ,  C12P19/30 ,  C12P19/34 ,  C12P21/00

CPC分类号： C12N15/1003 ,  C12N15/10 ,  C12P19/30 ,  C12P19/305 ,  C12P19/32

摘要： The invention provides novel and improved methods that allow effective capture of valuable active ingredients in biomass (e.g., DDGS) at cost-effective commercial scale. The invention also provides novel compositions of active ingredients with unique properties (e.g., nutritional values and enhanced bioavailability).

公开(公告)号：EP1233072B1

公开(公告)日：2006-08-02

申请号：EP00977869.7

申请日：2000-11-22

申请人： YAMASA CORPORATION

发明人： HAMAMOTO, Tomoki ,  NOGUCHI, Toshitada

IPC分类号： C12P19/30 ,  C12N9/90 ,  C12N15/09 ,  C12R1/125

CPC分类号： C12P19/305 ,  C12N9/90

摘要： A novel use of uridine diphosphate glucose 4-epimerase (also called uridine diphosphate galactose 4-epimerase). A method of converting uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) into uridine diphosphate N-acetylgalactoasmine (UDP-GalNAc) by using the above-described enzyme. Because of being practically usable and efficient, the method of synthesizing UDP-GalNAc by using the uridine diphosphate glucose 4-epimerase as described above and an UDP-GalNAc supplying system are highly useful industrially.

公开(公告)号：EP1233072A4

公开(公告)日：2003-05-21

申请号：EP00977869

申请日：2000-11-22

申请人： YAMASA CORP

发明人： HAMAMOTO TOMOKI ,  NOGUCHI TOSHITADA

IPC分类号： C12N9/90 ,  C12P19/30 ,  C12N15/09

CPC分类号： C12P19/305 ,  C12N9/90

摘要： A novel use of uridine diphosphate glucose 4-epimerase (also called uridine diphosphate galactose 4-epimerase). A method of converting uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) into uridine diphosphate N-acetylgalactoasmine (UDP-GalNAc) by using the above-described enzyme. Because of being practically usable and efficient, the method of synthesizing UDP-GalNAc by using the uridine diphosphate glucose 4-epimerase as described above and an UDP-GalNAc supplying system are highly useful industrially.

公开(公告)号：EP0980423A4

公开(公告)日：2003-04-23

申请号：EP98920288

申请日：1998-05-06

申请人： UNIV CARNEGIE MELLON

发明人： HENRY SUSAN A ,  PATTON JANA L ,  GRIAC PETER ,  KOHLWEIN SEPP D

IPC分类号： C12N1/15 ,  C12P7/18 ,  C12P7/64 ,  C12P9/00 ,  C12P13/00 ,  C12P19/28 ,  C12P19/30 ,  C12Q1/02 ,  C12P7/02

CPC分类号： C12P7/6481 ,  C12P7/18 ,  C12P9/00 ,  C12P13/001 ,  C12P19/305 ,  C12Q1/02 ,  G01N2405/04 ,  G01N2405/06

公开(公告)号：EP1233072A1

公开(公告)日：2002-08-21

申请号：EP00977869.7

申请日：2000-11-22

申请人： YAMASA CORPORATION

发明人： HAMAMOTO, Tomoki ,  NOGUCHI, Toshitada

IPC分类号： C12P19/30 ,  C12N9/90 ,  C12N15/09

CPC分类号： C12P19/305 ,  C12N9/90

摘要： The present invention relates to a new use of uridine diphosphate glucose 4-epimerase (also called uridine diphosphate galactose 4-epimerase), and a method of converting uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) to uridine diphosphate N-acetylgalactosamine (UDP-GalNAc) by using the said enzyme. The process for producing UDP-GalNAc by using the uridine diphosphate glucose 4-epimerase and the UDP-GalNAc supply system according to the present invention are practical and efficient, and greatly beneficial to the industries.

摘要翻译： 本发明涉及尿苷二磷酸葡萄糖4-差向异构酶（也称为尿苷二磷酸半乳糖4-差向异构酶）的新用途，以及将尿苷二磷酸N-乙酰葡糖胺（UDP-GlcNAc）转化为尿苷二磷酸N-乙酰半乳糖胺（UDP- GalNAc）。 通过使用根据本发明的尿苷二磷酸葡萄糖4-差向异构酶和UDP-GalNAc供应系统生产UDP-GalNAc的方法是实用和有效的，并且对该行业有很大的益处。

公开(公告)号：EP0971035A1

公开(公告)日：2000-01-12

申请号：EP98936727.1

申请日：1998-08-11

申请人： YAMASA CORPORATION

发明人： TAKENOUCHI, Kenji ,  ISHIGE, Kazuya ,  MIDORIKAWA, Yuichiro ,  OKUYAMA, Kiyoshi ,  HAMAMOTO, Tomoki ,  NOGUCHI, Toshitada

IPC分类号： C12P19/30

CPC分类号： C12N9/1205 ,  C12P19/305

摘要： A process for producing uridine diphosphate-N-acetylglucosamine (UDPAG) from uridylic acid (UMP) and N-acetylglucosamine by use of microorganism cells, characterized by adding N-acetylglucosamine kinase thereto.
According to the present invention, UDPAG can be efficiently produced even when N-acetylglucosamine is used as a substrate.

摘要翻译： 通过使用微生物细胞从尿苷酸（UMP）和N-乙酰葡糖胺生产尿苷二磷酸-N-乙酰氨基葡萄糖（UDPAG）的方法，其特征在于向其中加入N-乙酰葡糖胺激酶。 根据本发明，即使使用N-乙酰氨基葡糖作为基质，也能够有效地制造UDPAG。

公开(公告)号：EP0380470A4

公开(公告)日：1990-06-05

申请号：EP87902918

申请日：1987-03-24

申请人： GETTY SCIENT DEV CO

发明人： BETLACH MICHAEL R ,  DOHERTY DANIEL H ,  VANDERSLICE REBECCA W

IPC分类号： C12N15/09 ,  C12N1/21 ,  C12N15/00 ,  C12N15/52 ,  C12P19/30 ,  C12R1/01 ,  C12R1/145 ,  C12R1/19 ,  C12R1/64

CPC分类号： C12N15/52 ,  C12P19/305

公开(公告)号：EP0223264A2

公开(公告)日：1987-05-27

申请号：EP86116536.3

申请日：1983-06-02

申请人： SEITETSU KAGAKU CO., LTD.

发明人： Seno, Taiko ,  Okubo, Yasuto ,  Kawamura, Masao ,  Akutsu, Seiichi ,  Fukuda, Hirosuki

IPC分类号： C12Q1/48

CPC分类号： C07H19/06 ,  C12N9/90 ,  C12P19/305 ,  C12Q1/48 ,  G01N33/80 ,  Y10S435/839

摘要： There is disclosed a method for measuring the activity of a-N-acetylgalactosaminyl transferase by means of the conversion of Type O red blood cells to Type A ones, characterized by the direct use, as the substrate for the conversion reaction, of a reaction solution obtained by enzymatically converting uridine diphosphate-N-acetylglucosamine to uridine diphosphate-N-acetylgalactosamine.

摘要翻译： 公开了通过将O型红细胞转化为A型，直接使用反应溶液作为转化反应的底物的方法，测量α-N-乙酰半乳糖胺转移酶的活性的方法 通过将尿苷二磷酸-N-乙酰葡糖胺酶促转换成尿苷二磷酸-N-乙酰半乳糖来获得。

公开(公告)号：EP3128013A1

公开(公告)日：2017-02-08

申请号：EP15382419.8

申请日：2015-08-07

申请人： Institut Univ. de Ciència i Tecnologia, S.A.

发明人： PÉREZ OZCÁRIZ, Sergio ,  PASCUAL GILABERT, Marta ,  FERNÁNDEZ FERNÁNDEZ, Carmen María ,  CASTELLS BOLIART, Josep

IPC分类号： C12P19/30 ,  C12P9/00 ,  C12P17/16

CPC分类号： C12P17/16 ,  C12P9/00 ,  C12P19/305

摘要： The invention relates to a new synthethic process for obtaining compounds of formula (I) from compounds of formula (II) by means of deaminase enzymes.

摘要翻译： 本发明涉及通过脱氨酶从式（II）化合物获得式（I）化合物的新合成方法。

公开(公告)号：EP3097200A1

公开(公告)日：2016-11-30

申请号：EP15704105.4

申请日：2015-01-26

申请人： SynAffix B.V.

发明人： VAN DELFT, Floris Louis ,  VAN GEEL, Remon ,  WIJDEVEN, Maria Antonia ,  HEESBEEN, Ryan

IPC分类号： C12P19/18 ,  C07H17/075 ,  C07H19/10 ,  C07K16/00 ,  C07K19/00

CPC分类号： C12P19/18 ,  C07H17/075 ,  C07H19/06 ,  C07H19/10 ,  C07K16/22 ,  C07K16/241 ,  C07K16/2863 ,  C07K16/30 ,  C07K16/32 ,  C07K2317/21 ,  C07K2317/24 ,  C07K2317/41 ,  C07K2317/76 ,  C12N9/1051 ,  C12P19/305 ,  C12P21/005 ,  C12Y204/01

摘要： The present invention relates to a process for attaching an N-acetylgalactosamine- (hetero)arylmoiety to an N-acetylglucosaminemoiety, the process comprising the step of contacting the N-acetylgalactosamine-(hetero)arylmoiety with the N- acetylglucosaminemoiety in the presence of a mutant galactosyltransferase, wherein the N-acetylglucosaminemoiety is according to Formula (1)the N- acetylgalactosamine-(hetero)arylmoiety is according to Formula (2): In a particularly preferred embodiment of the process according to the invention, the N-acetylgalactosamine-(hetero)arylmoiety comprises a 1,3-dipole functional group, and the N-acetylglucosaminemoiety is a terminal GlcNAc moiety of a glycoprotein glycan. The invention further relates to a productobtainable by the process according to the invention, in particular to glycoproteins. Also, the invention relates to several compounds comprising an N-acetylgalactosamine-(hetero)arylmoiety.

摘要翻译： 本发明涉及一种用于附连到N-acetylgalactosamine-（杂）arylmoiety到N-acetylglucosaminemoiety，该方法包括使与N- acetylglucosaminemoiety的N acetylgalactosamine-（杂）arylmoiety中的存在的步骤 突变体半乳糖转移酶，worin的N acetylglucosaminemoiety是雅丁式（1）的N个acetylgalactosamine-（杂）arylmoiety是雅丁到式（2）：在这个过程中雅丁到本发明的一个特别优选的实施方式中，N-acetylgalactosamine- （杂）arylmoiety包括1.3偶极官能团，并且N acetylglucosaminemoiety是糖蛋白的聚糖的末端GlcNAc部分。 本发明还涉及到一个productobtainable由过程gemäß所述的发明，特别是糖蛋白。 所以，（杂）arylmoiety本发明涉及的几种化合物包含N- acetylgalactosamine-的。