公开(公告)号：US20250144401A1

公开(公告)日：2025-05-08

申请号：US19014344

申请日：2025-01-09

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Jacob Leisner Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M60/148 ,  A61M60/122 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/205 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/804 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/38 ,  F04D29/52 ,  F04D29/54

Abstract: Apparatus and methods are described including a left-ventricular assist device that includes a self-expandable impeller and a pump-outlet tube. The impeller is configured to be deployed in a left ventricle of a subject and to pump blood from the subject's left ventricle to an aorta of the subject via the pump-outlet tube, for a period of more than two days. The impeller is configured to provide blood flow of more than 4.5 L/min, when pumping against a pressure gradient of 50 mmHg. Other applications are also described.

公开(公告)号：US20250114593A1

公开(公告)日：2025-04-10

申请号：US18933759

申请日：2024-10-31

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR ,  David LINSKY

IPC: A61M60/855 ,  A61M60/13 ,  A61M60/17 ,  A61M60/216 ,  A61M60/408 ,  A61M60/833

Abstract: Apparatus and methods are described including a delivery catheter and a delivery tube configured to extend from outside a subject's body into the subject's left ventricle via the delivery catheter. A locking unit is configured to couple to a proximal end of the delivery catheter and the delivery tube is configured to pass through the locking unit. The locking unit includes at least one internal seal configured to surround the delivery tube and to inhibit backflow of blood of the subject, from the delivery catheter, through the locking unit. The locking unit also includes a clip, which has only two states, which consist of a closed state, in which the clip grips the delivery tube so as to inhibit movement of the delivery tube relative to the delivery catheter, and an open state, in which the clip does not grip the delivery tube. Other applications are also described.

公开(公告)号：US20250073448A1

公开(公告)日：2025-03-06

申请号：US18952273

申请日：2024-11-19

Applicant: MAGENTA MEDICAL LTD

Inventor： Ehud Schwammenthal ,  Yosi Tuval ,  Daniel Glozman ,  Tom Shtendel ,  Gad Lubinsky

IPC: A61M60/414 ,  A61M60/13 ,  A61M60/148 ,  A61M60/237 ,  A61M60/515 ,  A61M60/523 ,  A61M60/531 ,  A61M60/585 ,  A61M60/808 ,  A61M60/833 ,  A61M60/865

Abstract: Apparatus and methods are described including an impeller that includes an impeller frame that comprises proximal and distal end portions and a plurality of blades. Each of the impeller blades includes a curved elongate element and at least one radial element extending radially from the curved elongate element toward a longitudinal axis of the impeller frame. Other applications are also described.

公开(公告)号：US20250010057A1

公开(公告)日：2025-01-09

申请号：US18888529

申请日：2024-09-18

Applicant: MAGENTA MEDICAL LTD

Inventor： Ori Friedland ,  Yuval Zipory ,  Yuri Sudin ,  Ayelet Haimy ,  Ehud Schwammenthal ,  Yosi Tuval ,  Tak Gee Cheung

IPC: A61M60/531 ,  A61B17/12 ,  A61M60/13 ,  A61M60/178 ,  A61M60/216 ,  A61M60/546 ,  A61M60/833 ,  A61M60/867

Abstract: Apparatus and methods are described for use with a venous system of a subject that includes one or more tributary vessels that flow into a vein at junctions. A blood-pump-catheter includes a material configured to be placed at a downstream location that is downstream of the junctions and to at least partially occlude blood flow through the vein. The material defines a blood-outlet opening. A blood pump pumps blood from a region of the vein that is adjacent to the junctions, and through the blood-outlet opening. A blood-flow pathway directs upstream venous blood flow from an upstream location that is upstream of the junctions, to downstream of the material, without the upstream venous blood flow being pumped by the pump. Other applications are also described.

公开(公告)号：US20240285932A1

公开(公告)日：2024-08-29

申请号：US18652962

申请日：2024-05-02

Applicant: Magenta Medical Ltd

Inventor： Yosi Tuval ,  Gad Lubinsky ,  Victor Troshin ,  Hagit Zemer Harel ,  Ori Friedland ,  Daniel Rosenblum ,  Avi Rozenfeld

IPC: A61M60/808 ,  A61M60/13 ,  A61M60/174 ,  A61M60/237 ,  A61M60/414 ,  A61M60/81 ,  A61M60/825

CPC classification number: A61M60/808 ,  A61M60/13 ,  A61M60/174 ,  A61M60/237 ,  A61M60/414 ,  A61M60/81 ,  A61M60/825

Abstract: Apparatus and methods are described including a ventricular assist device that includes an axial shaft and an impeller disposed on the axial shaft, the impeller being configured to pump blood. A frame is disposed around the impeller. The distal end of the axial shaft is configured to engage with a distal thrust bearing such as to prevent the axial shaft from undergoing axial motion in response to variations in the pressure gradient against which the impeller pumps blood. An impeller-stabilizing spring is disposed around the axial shaft between a distal end of the impeller and the thrust bearing, the impeller-stabilizing spring being configured to stabilize the distal end of the impeller. Other applications are also described.

公开(公告)号：US20240277990A1

公开(公告)日：2024-08-22

申请号：US18635275

申请日：2024-04-15

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/178 ,  A61M60/216 ,  A61M60/408 ,  A61M60/419 ,  A61M60/497 ,  A61M60/508 ,  A61M60/531 ,  A61M60/818 ,  A61M60/829 ,  A61M60/865

CPC classification number: A61M60/178 ,  A61M60/216 ,  A61M60/408 ,  A61M60/419 ,  A61M60/497 ,  A61M60/508 ,  A61M60/531 ,  A61M60/818 ,  A61M60/829 ,  A61M60/865

Abstract: Apparatus and methods are provided, including a left-ventricular assist device that includes an impeller configured for insertion into a subject's left ventricle. A delivery tube passes through the subject's aorta, from outside the subject into the left ventricle. The delivery tube includes an outer layer that varies along a length of the delivery tube such that a flexural rigidity of the delivery tube at a first portion of the delivery tube, which is configured to traverse the aortic valve, is less than the flexural rigidity at a second portion, which is configured to traverse at least a portion of the aortic arch, and the flexural rigidity at the second portion is less than the flexural rigidity at a third portion, which is configured to traverse the descending aorta. Other applications are also described.

公开(公告)号：US20240189571A1

公开(公告)日：2024-06-13

申请号：US18444972

申请日：2024-02-19

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M60/148 ,  A61M60/122 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/205 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/804 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/38 ,  F04D29/52 ,  F04D29/54

CPC classification number: A61M60/148 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/382 ,  F04D29/526 ,  F04D29/545 ,  A61M60/122 ,  A61M60/205 ,  A61M60/804 ,  A61M2205/0216 ,  A61M2205/3344 ,  A61M2230/30

Abstract: Apparatus and methods are described including a blood pump that includes an impeller configured to be delivered through vasculature of a subject while the impeller is in a radially-constrained configuration. The impeller is configured to self-expand to a non-radially-constrained configuration, and to pump blood while in the non-radially-constrained configuration. A ratio between (a) a diameter of the impeller when the impeller is in its non-radially-constrained configuration at a location at which the diameter of the impeller is at its maximum and (b) a diameter of the impeller when the impeller is in its radially-constrained configuration is greater than 7:2. Other applications are also described.

公开(公告)号：US11883274B2

公开(公告)日：2024-01-30

申请号：US16677893

申请日：2019-11-08

Applicant: Magenta Medical Ltd.

Inventor： Ehud Schwammenthal ,  Yosi Tuval ,  Daniel Glozman

IPC: A61M1/12 ,  A61F2/07 ,  A61M60/135 ,  A61M60/422 ,  A61M60/833 ,  A61M60/411 ,  A61M60/861 ,  A61M60/523 ,  A61M60/237 ,  A61M60/808 ,  A61M60/825 ,  A61M60/13 ,  A61M60/81 ,  A61M60/33 ,  A61B5/0205 ,  A61M60/148 ,  A61M60/414 ,  A61M60/896

CPC classification number: A61F2/07 ,  A61B5/02055 ,  A61M60/13 ,  A61M60/135 ,  A61M60/237 ,  A61M60/33 ,  A61M60/411 ,  A61M60/422 ,  A61M60/523 ,  A61M60/808 ,  A61M60/81 ,  A61M60/825 ,  A61M60/833 ,  A61M60/861 ,  A61M60/148 ,  A61M60/414 ,  A61M60/896 ,  A61M2207/00 ,  A61M2210/1082 ,  A61M2210/12

Abstract: Apparatus and methods are described for improving renal function of a patient, including mechanically occluding the patient's inferior vena cava downstream of the renal vein ostium to form an upstream region and a downstream region of the inferior vena cava, and mechanically pumping blood through the inferior vena cava from the upstream region to a discharge location in the downstream region while the inferior vena cava is occluded, wherein the blood remains in the inferior vena cava while being mechanically pumped. Other applications are also described.

公开(公告)号：US11844592B2

公开(公告)日：2023-12-19

申请号：US17077769

申请日：2020-10-22

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61B5/0215 ,  F04D15/00 ,  F04D29/041 ,  F04D29/042 ,  F04D25/02 ,  F04D29/18 ,  F04D29/24 ,  F04D7/00 ,  A61M60/135 ,  A61M60/148 ,  A61M60/857 ,  F04D3/02 ,  A61M60/422 ,  A61M60/414 ,  A61M60/419 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/896 ,  A61M60/237 ,  A61M60/531 ,  A61M60/554

CPC classification number: A61B5/0215 ,  A61M60/135 ,  A61M60/148 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/554 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896 ,  F04D3/02 ,  F04D7/00 ,  F04D15/0066 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042 ,  F04D29/181 ,  F04D29/247 ,  A61M2205/0266 ,  A61M2205/3317 ,  A61M2205/3327 ,  A61M2205/3334 ,  A61M2205/3344 ,  A61M2205/3365 ,  A61M2205/50 ,  A61M2230/04 ,  A61M2230/30

Abstract: Apparatus and methods are described including a ventricular assist device that includes an impeller configured to be placed inside a subject's left ventricle. A frame is disposed around the impeller, the frame defining generally-cylindrical central portion, and a proximal conical portion that widens from a proximal end of the frame to a proximal end of the generally-cylindrical central portion. A motor drives the impeller to pump blood from the left ventricle to the subject's aorta, by rotation of the impeller. The impeller is configured to be disposed at least partially within the proximal conical portion of the frame during at least some of a time during which the impeller rotates. Other applications are also described.

公开(公告)号：US20230233841A1

公开(公告)日：2023-07-27

申请号：US18130698

申请日：2023-04-04

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Ehud Schwammenthal ,  Daniel Glozman ,  Gad Lubinksy

IPC: A61M60/833 ,  A61M60/416 ,  A61M60/13 ,  A61M60/216 ,  A61M60/804 ,  A61M60/818 ,  A61M60/585 ,  A61M60/531 ,  A61M60/139

CPC classification number: A61M60/833 ,  A61M60/416 ,  A61M60/13 ,  A61M60/216 ,  A61M60/804 ,  A61M60/818 ,  A61M60/585 ,  A61M60/531 ,  A61M60/139 ,  A61M60/414

Abstract: Apparatus and methods are described including a catheter, and first and second impellers configured to be inserted into a subject's body via the catheter, the first and second impellers being disposed in series with each other. A first impeller cage is disposed around the first impeller, and a second impeller cage is disposed around the second impeller. A sleeve extends longitudinally along more than 50 percent of a distance between the first and second impellers. Other applications are also described.