COMPOSITIONS AND METHODS FOR ASSAY MEASUREMENTS

    公开(公告)号:US20230279290A1

    公开(公告)日:2023-09-07

    申请号:US18145735

    申请日:2022-12-22

    IPC分类号: C09K11/02 C12Q1/6816

    CPC分类号: C09K11/02 C12Q1/6816

    摘要: The disclosure relates to novel compositions comprising an electrochemiluminescence (ECL) co-reactant. In embodiments, the composition further comprises an ionic component, a surfactant, or combination thereof. In embodiments, the ECL co-reactant is triethanolamine (TEA), tert-butyldiethanolamine (tBDEA), methyldibutylethanolamine (MDEA), 3-[Bis-(2-hydroxy-ethyl)-amino]-propane-1-sulfonic acid (DEA-PS), or a combination thereof. Methods of using the compositions and kits comprising the compositions are also provided herein, including methods using ECL-labeled oligonucleotide probes having quenching moieties.