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公开(公告)号:USD866927S1
公开(公告)日:2019-11-19
申请号:US29583578
申请日:2016-11-07
申请人: Sarfaraz K. Niazi
设计人: Sarfaraz K. Niazi
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公开(公告)号:US20180147552A1
公开(公告)日:2018-05-31
申请号:US15362481
申请日:2016-11-28
申请人: Sarfaraz K. Niazi
发明人: Sarfaraz K. Niazi
CPC分类号: B01J19/285 , B01J19/006 , B01J19/2445 , B01J2219/00189 , B01J2219/00765 , C12M27/16 , C12M35/00
摘要: A physical, chemical and biological process device operating under zero gravity and shaken by low energy mechanical and magnetic means is disclosed.
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公开(公告)号:US20180024137A1
公开(公告)日:2018-01-25
申请号:US15720755
申请日:2017-09-29
申请人: Sarfaraz K. Niazi
发明人: Sarfaraz K. Niazi
CPC分类号: G01N33/6803 , G01N21/6486
摘要: The present disclosure provides methods to assess structural similarity of a first biomolecule and a second biomolecule by detecting one or more responses of the first and second biomolecule to thermodynamic stress conditions induced by osmotic and dielectric changes including, detecting a shift in fluorescence emission and/or a change in the intensity of the emission.
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公开(公告)号:US20170101435A1
公开(公告)日:2017-04-13
申请号:US14881795
申请日:2015-10-13
申请人: Sarfaraz K. Niazi
发明人: Sarfaraz K. Niazi
CPC分类号: C12M47/10
摘要: The present invention relates to an apparatus capable of harvesting a recombinant protein from a bioreactor having a porous container comprised of a chromatography medium capable of binding the recombinant protein and a method of use thereof.
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公开(公告)号:US09587283B2
公开(公告)日:2017-03-07
申请号:US14738399
申请日:2015-06-12
申请人: Sarfaraz K. Niazi
发明人: Sarfaraz K. Niazi
摘要: A method of homogenously mixing the contents of a plurality of bioreactors by providing a receiving container capable of holding an appropriate quantity of the liquid and repeatedly raising and lowering the receiving container to a position above or below the position of the bioreactors resulting in mixing the contents of the bioreactors.
摘要翻译: 一种通过提供能够保持适量的液体并且将接收容器反复升高和降低到生物反应器的位置上方或下方的位置的容纳容器来均匀地混合多个生物反应器的内容物的方法,从而使内容物 的生物反应器。
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公开(公告)号:US20160166949A1
公开(公告)日:2016-06-16
申请号:US15050982
申请日:2016-02-23
申请人: Sarfaraz K. Niazi
发明人: Sarfaraz K. Niazi
CPC分类号: B01D15/22 , B01D15/203 , B01D15/327 , B01D15/361 , B01D15/3804 , B01D15/424 , B01J20/2805 , C07K1/14 , C07K1/165 , C07K1/18 , C07K1/20 , C07K1/22
摘要: A chromatography column that captures components in a process liquid in a free flow state and allows elution in steps is described.
摘要翻译: 描述了在自由流动状态下捕获处理液体中的组分并允许步骤洗脱的色谱柱。
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公开(公告)号:US09364776B2
公开(公告)日:2016-06-14
申请号:US14191989
申请日:2014-02-27
申请人: Sarfaraz K. Niazi
发明人: Sarfaraz K. Niazi
CPC分类号: C12N1/20 , A01N1/0247 , B01D29/114 , B01D29/15 , B01D29/64 , B01D29/66 , C07K1/34 , C07K14/505 , C12M21/00 , C12M23/26 , C12M29/04 , C12M29/10 , C12M47/02 , C12M47/10
摘要: A method and an apparatus for separating suspended matter from liquid includes a concentrator filter that draws the liquid out of the suspension while the filter kept unblocked by a sparging filter that allows scrubbing of the concentrator filter by gas bubbles. This invention can be used to replace cross-flow filtration and centrifugation in the bioprocess industry and to reduce the volume of suspensions to concentrate the yield of the end product in the chemical industry.
摘要翻译: 用于从液体中分离悬浮物的方法和装置包括:浓缩器过滤器,其将液体从悬浮液中抽出,同时过滤器通过鼓泡过滤器保持开启状态,该喷射过滤器允许通过气泡洗涤聚光过滤器。 本发明可用于替代生物过程工业中的交叉流过滤和离心,并减少悬浮液的体积以将最终产物的产率集中在化学工业中。
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公开(公告)号:US20140225727A1
公开(公告)日:2014-08-14
申请号:US13764147
申请日:2013-02-11
申请人: Sarfaraz K. NIAZI
发明人: Sarfaraz K. NIAZI
IPC分类号: B60Q1/34
CPC分类号: B60Q1/0035 , B60Q1/38
摘要: Turn signals for moving vehicles along both sides of the vehicle are reported.
摘要翻译: 报告车辆两侧的车辆转向信号。
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公开(公告)号:US20120149885A1
公开(公告)日:2012-06-14
申请号:US13400627
申请日:2012-02-21
申请人: Sarfaraz K. Niazi
发明人: Sarfaraz K. Niazi
CPC分类号: C07K1/165 , B01D15/02 , B01D15/1892 , B01D15/22 , B01D15/3809 , B01F7/245 , C07K1/22 , C07K1/34 , C12M1/02 , C12M47/10 , C12M47/12 , C12Q1/06 , C12Q1/68 , G01N30/20
摘要: Large-scale downstream processing of secreted recombinant proteins is provided in a single device, wherein the contents of a plurality of bioreactors are combined simultaneous to their harvesting and purification resulting in significant savings of time and the cost of manufacturing.
摘要翻译: 在单个装置中提供分泌重组蛋白的大规模下游加工,其中多个生物反应器的内容物与其收获和纯化同时组合,导致显着节省时间和制造成本。
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公开(公告)号:US20110117538A1
公开(公告)日:2011-05-19
申请号:US12618330
申请日:2009-11-13
申请人: Sarfaraz K. Niazi
发明人: Sarfaraz K. Niazi
CPC分类号: C12M29/06
摘要: Bioreactors suitable for housing a predetermined volume of liquid comprising nutrient medium and biological culture comprising: (a) a container having at least one interior wall; (b) at least one nutrient medium inlet; (c) at least one liquid outlet; (d) at least one gas inlet; (e) at least one gas outlet; and (f) at least one cylindrical sparging filter attached to the at least one gas inlet, wherein the sparging filter comprises a plurality of pores along its axis which permit gas to be emitted radially from the sparging filter into the liquid, wherein the diameter of the plurality of pores does not exceed about 50 μm, and wherein the orientation of the at least one sparging filter within the container provides for immersion of the plurality of pores within the liquid and substantially uniform distribution of emitted gas throughout the liquid, and related methods of using said bioreactors to prepare various biological products.
摘要翻译: 适于容纳包含营养培养基和生物培养物的预定体积的液体的生物反应器,包括:(a)具有至少一个内壁的容器; (b)至少一个营养介质入口; (c)至少一个液体出口; (d)至少一个气体入口; (e)至少一个气体出口; 和(f)至少一个连接到所述至少一个气体入口的圆柱形喷射过滤器,其中所述喷射过滤器包括沿其轴线的多个孔,其允许气体从所述喷射过滤器径向射入液体,其中, 多个孔不超过约50μm,并且其中容器内的至少一个喷射过滤器的取向提供了多个孔浸入液体内并且基本上均匀地分布排出的气体遍及液体,并且相关方法 使用所述生物反应器来制备各种生物制品。
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