公开(公告)号：US5991324A

公开(公告)日：1999-11-23

申请号：US41474

申请日：1998-03-11

申请人： David S. Knowles ,  James H. Azzola ,  Herve A. Besaucele ,  Palash P. Das ,  Alexander I. Ershov ,  Igor V. Fomenkov ,  Tibor Juhasz ,  Robert G. Ozarski ,  William N. Partlo ,  Daniel A. Rothweil ,  Richard L. Sandstrom ,  Richard C. Ujazdowski ,  Tom A. Watson ,  Richard M. Ness

发明人： David S. Knowles ,  James H. Azzola ,  Herve A. Besaucele ,  Palash P. Das ,  Alexander I. Ershov ,  Igor V. Fomenkov ,  Tibor Juhasz ,  Robert G. Ozarski ,  William N. Partlo ,  Daniel A. Rothweil ,  Richard L. Sandstrom ,  Richard C. Ujazdowski ,  Tom A. Watson ,  Richard M. Ness

IPC分类号： H01S3/038 ,  G03F7/20 ,  H01S3/02 ,  H01S3/03 ,  H01S3/036 ,  H01S3/0971 ,  H01S3/1055 ,  H01S3/139 ,  H01S3/225 ,  H01S3/22

CPC分类号： G01J9/0246 ,  G03F7/70025 ,  G03F7/70041 ,  G03F7/70358 ,  G03F7/70558 ,  G03F7/70575 ,  H01S3/02 ,  H01S3/03 ,  H01S3/036 ,  H01S3/0971 ,  H01S3/1055 ,  H01S3/225 ,  H01S3/1392

摘要： A reliable, modular, production quality narrow-band KrF excimer laser capable of producing 10 mJ laser pulses at 1000 Hz with a bandwidth of about 0.6 pm or less. The present invention is especially suited to long-term round-the-clock operation in the lithographic production of integrated circuits. Improvements over prior art lasers include a single upstream preionizer tube and acoustic baffles. A preferred embodiment includes reduced fluorine concentration, an anode support bar shaped to reduce aerodynamic reaction forces on blower bearings, a modified pulse power system providing faster pulse rise time, an output coupler with substantially increased reflectivity, a line narrowing module with CaF prism beam expanders, a more accurate wavemeter, a laser computer controller programmed with new and improved pulse energy control algorithm.

摘要翻译： 一种可靠，模块化，生产质量好的窄带KrF准分子激光器，能够以1000Hz的频率产生10mJ的激光脉冲，带宽约为0.6μm或更小。 本发明特别适用于集成电路的平版印刷生产中的长期全天候操作。 现有技术的激光器的改进包括单个上游预分解器管和声学挡板。 优选的实施例包括减少的氟浓度，阳极支撑杆形状以减小鼓风机轴承上的空气动力反作用力，改进的脉冲电源系统提供更快的脉冲上升时间，输出耦合器具有显着增加的反射率，具有CaF棱镜扩束器的线窄化模块 ，更准确的波长计，激光计算机控制器编程，具有新的改进的脉冲能量控制算法。

公开(公告)号：US5978405A

公开(公告)日：1999-11-02

申请号：US36158

申请日：1998-03-06

申请人： Tibor Juhasz ,  Richard C. Ujazdowski ,  Herve A. Besaucele ,  Robert G. Ozarski ,  James H. Azzola

发明人： Tibor Juhasz ,  Richard C. Ujazdowski ,  Herve A. Besaucele ,  Robert G. Ozarski ,  James H. Azzola

IPC分类号： H01S3/038 ,  H01S3/032 ,  H01S3/036 ,  H01S3/225 ,  H01S3/22

CPC分类号： H01S3/036

摘要： A laser chamber has angled reflectors that reflect acoustic and shock waves away from the laser discharge area to minimize acoustic and shock wave disturbances. The angled reflector may have different configurations to assist in the dissipation of the acoustic and shock waves. For example, the angled reflector may have a modulated reflective surface, such as having grooves or holes defined within the surface. Further, the angled reflector may have a reflective surface with acoustic and shock wave absorbing properties. The reflective surface with absorbent properties may be a felt metal or have multiple layered porous surfaces. In addition, the walls of the laser chamber may be modulated to assist in the dissipation of the acoustic waves and shock waves through absorption, scattering, and by generating interference within the reflected waves. Multiple layered porous surfaces may be used along the walls to absorb and scatter incident waves. The walls of the laser chamber may also be covered with an acoustic and shock wave absorbing material, such as felt metal. In other embodiments, the walls of the laser chamber are modulated with grooves, such as triangular or rectangular horizontal grooves, which scatter incident waves and generate interference within reflected waves.

摘要翻译： 激光室具有倾斜的反射器，其将声波和冲击波反射离开激光放电区域，以最小化声波和冲击波干扰。 成角度的反射器可以具有不同的构造以辅助声波和冲击波的消散。 例如，成角度的反射器可以具有调制的反射表面，例如在表面内限定有凹槽或孔。 此外，成角度的反射器可以具有具有声波和冲击波吸收特性的反射表面。 具有吸收性能的反射表面可以是毡状金属或具有多层多孔表面。 此外，可以调制激光室的壁，以通过吸收，散射和在反射波内产生干涉来帮助消除声波和冲击波。 沿着壁可以使用多层多孔表面来吸收和散射入射波。 激光室的壁也可以用诸如毛毡金属的声波和冲击波吸收材料覆盖。 在其他实施例中，激光室的壁由诸如三角形或矩形水平凹槽的凹槽调制，这些凹槽散射入射波并在反射波内产生干涉。

公开(公告)号：US08845624B2

公开(公告)日：2014-09-30

申请号：US12824107

申请日：2010-06-25

申请人： Ferenc Raksi ,  Tibor Juhasz

发明人： Ferenc Raksi ,  Tibor Juhasz

IPC分类号： A61B18/18 ,  A61F9/009

CPC分类号： A61F9/009

摘要： A patient interface for an ophthalmic system can include an attachment module, attachable to the ophthalmic system, and a contact module, configured to accommodate a viscoelastic substance between the patient interface and a procedure eye. The viscoelastic substance can include a fluid, a liquid, a gel, a cream, an artificial tear, a film, an elastic material, or a viscous material. The refractive index of the viscoelastic substance can be within a range of approximately 1.24-1.52 at an operating wavelength of the ophthalmic system. The patient interface can further include input ports, output ports, and a suction system. It can be an integrated design or a multi-piece patient interface. The viscoelastic substance can be provided by injection, on the cornea, at the contact module, or in a space bounded by soft elastic films or membranes, such as in a bag.

摘要翻译： 用于眼科系统的患者界面可以包括可连接到眼科系统的附接模块，以及接触模块，其构造成在患者界面和手术眼之间容纳粘弹性物质。 粘弹性物质可以包括流体，液体，凝胶，霜，人造泪，膜，弹性材料或粘性材料。 在眼科系统的工作波长下，粘弹性物质的折射率可以在约1.24-1.52的范围内。 患者界面还可以包括输入端口，输出端口和抽吸系统。 它可以是一体化设计或多片式患者界面。 粘弹性物质可以通过注射，角膜，接触模块，或由柔软的弹性膜或膜（例如袋子）限定的空间来提供。

公开(公告)号：US07371230B2

公开(公告)日：2008-05-13

申请号：US11277477

申请日：2006-03-24

申请人： Kyle R. Webb ,  Michael F. Brownell ,  Christopher Horvath ,  Tibor Juhasz ,  Ronald M. Kurtz ,  Leszlo I. Nagy ,  Mark W. Ross ,  Carlos G. Suarez

发明人： Kyle R. Webb ,  Michael F. Brownell ,  Christopher Horvath ,  Tibor Juhasz ,  Ronald M. Kurtz ,  Leszlo I. Nagy ,  Mark W. Ross ,  Carlos G. Suarez

IPC分类号： A61B18/18

CPC分类号： A61F9/009 ,  A61B2017/306 ,  A61F9/008 ,  A61F2009/00846

摘要： An interface for coupling an eye to a surgical laser is disclosed. A lens cone includes a base ring opposite an apex ring. The base ring defines a first plane and is adapted to couple to the delivery tip of the laser such that the first plane has a predetermined position relative to the delivery tip. An applanation lens is affixed to the apex ring and has a surface disposed in a second plane such that the second plane is parallel to and has a predetermined position relative to the first plane. A gripper is engagable with the lens cone. An attachment ring is affixed to the gripper and is adapted to couple to the anterior surface of the eye. When the lens cone and gripper are engaged, the applanation lens contacts the anterior surface of the eye, placing the anterior surface in spatial registration with the delivery tip.

摘要翻译： 公开了一种用于将眼睛联接到手术激光器的界面。 透镜锥体包括与顶点环相对的基座环。 基座限定第一平面并且适于联接到激光器的输送末端，使得第一平面相对于输送末端具有预定位置。 压平透镜固定到顶点环上，并且具有设置在第二平面中的表面，使得第二平面相对于第一平面平行并具有预定位置。 夹具可与透镜锥接合。 附接环固定在夹持器上并适于联接到眼睛的前表面。 当透镜锥体和夹持器接合时，压平透镜接触眼睛的前表面，将前表面与输送尖端空间对准。

公开(公告)号：US20080082088A1

公开(公告)日：2008-04-03

申请号：US11469941

申请日：2006-09-05

申请人： Ronald M. Kurtz ,  Gagik Jotyan ,  Tibor Juhasz ,  Melvin A. Sarayba

发明人： Ronald M. Kurtz ,  Gagik Jotyan ,  Tibor Juhasz ,  Melvin A. Sarayba

IPC分类号： A61B18/18

CPC分类号： A61F2/142 ,  A61F9/00831 ,  A61F9/009 ,  A61F9/013 ,  A61F2009/00857 ,  A61F2009/00872

摘要： A system and method for resecting and transplanting corneal tissue is disclosed. In a recipient cornea, a resection depth from the anterior surface of the recipient cornea is determined based upon a biomechanical model of the recipient cornea. A resection incision for resecting a posterior portion of the recipient cornea is made at the resection depth. Preferably, the incision is made using a surgical laser. Optionally, a contact lens may be placed against the anterior surface of the recipient cornea, wherein the shape of the anterior surface is conformed to the shape of the contact lens.

摘要翻译： 公开了一种切割和移植角膜组织的系统和方法。 在受体角膜中，根据接受者角膜的生物力学模型确定来自接受者角膜前表面的切除深度。 在切除深度处进行切除接受者角膜后部的切除切口。 优选地，使用手术激光器进行切口。 可选地，隐形眼镜可以抵靠接受者角膜的前表面放置，其中前表面的形状符合隐形眼镜的形状。

公开(公告)号：US07018376B2

公开(公告)日：2006-03-28

申请号：US10865165

申请日：2004-06-10

申请人： R. Kyle Webb ,  Michael F. Brownell ,  Christopher Horvath ,  Tibor Juhasz ,  Ronald M. Kurtz ,  Laszlo I. Nagy ,  Mark W. Ross ,  Carlos G. Suarez

发明人： R. Kyle Webb ,  Michael F. Brownell ,  Christopher Horvath ,  Tibor Juhasz ,  Ronald M. Kurtz ,  Laszlo I. Nagy ,  Mark W. Ross ,  Carlos G. Suarez

IPC分类号： A61B18/18

CPC分类号： A61F9/009 ,  A61B2017/306 ,  A61F9/008 ,  A61F2009/00846

摘要： A method for applanating an anterior surface of a cornea and coupling the eye to a surgical laser is disclosed. A interface is provided which has a central orifice and top and bottom surfaces. A suction ring is removably coupled to the bottom surface of the interface. The interface is positioned over an operative area of an eye, such that the suction ring comes into proximate contact with the surface of the eye. A suction is applied to the suction ring to stabilize the position of the interface relative to the operative area of the eye. An applanation lens is positioned in proximate contact with the operative area of the eye. Finally, the applanation lens is coupled to the interface to stabilize the position of the lens relative to the operative area of the eye.

摘要翻译： 公开了一种用于压平角膜的前表面并将眼睛联接到手术激光的方法。 提供了一个具有中心孔和顶部和底部表面的界面。 吸入环可拆卸地联接到界面的底表面。 界面定位在眼睛的操作区域上方，使得吸入环与眼睛的表面接近接触。 吸力被施加到吸入环，以稳定界面相对于眼睛的操作区域的位置。 压平透镜被定位成与眼睛的操作区域紧密接触。 最后，扁平透镜耦合到界面以稳定透镜相对于眼睛的操作区域的位置。

公开(公告)号：US06992765B2

公开(公告)日：2006-01-31

申请号：US10269340

申请日：2002-10-11

申请人： Christopher Horvath ,  Ruben Zadoyan ,  Ferenc Raksi ,  Zsolt Bor ,  Guy Vern Holland ,  Tibor Juhasz

发明人： Christopher Horvath ,  Ruben Zadoyan ,  Ferenc Raksi ,  Zsolt Bor ,  Guy Vern Holland ,  Tibor Juhasz

IPC分类号： G01B11/00

CPC分类号： G01B11/272 ,  A61F9/008 ,  A61F9/00825 ,  A61F9/009 ,  A61F2009/00844 ,  A61F2009/00848 ,  A61F2009/00872 ,  B23K26/04 ,  G01B9/02 ,  G01B11/00

摘要： The present invention generally relates to a method and system for determining the position and alignment of a plane in relation to an intersecting axis and using that known position and alignment to allow for corrections to be made when using the plane as a reference plane. More particularly, the invention relates to a method and system for determining the angle of tilt of a planar surface in relation to a laser beam, and using the determined angle of tilt to calculate a correction factor to be applied to the laser beam. Briefly stated, the method and system ultimately calculates a correction factor, z-offset, that is applied when using the laser beam in a procedure.

摘要翻译： 本发明一般涉及用于确定平面相对于交叉轴线的位置和对准的方法和系统，并且使用该已知位置和对准来允许在使用该平面作为参考平面时进行校正。 更具体地，本发明涉及一种用于确定平面相对于激光束的倾斜角度的方法和系统，并且使用确定的倾斜角度来计算要施加到激光束的校正因子。 简而言之，该方法和系统最终计算在过程中使用激光束时应用的校正因子z偏移。

公开(公告)号：US06902561B2

公开(公告)日：2005-06-07

申请号：US10394368

申请日：2003-03-21

申请人： Ronald M. Kurtz ,  Tibor Juhasz ,  Peter Goldstein ,  Imre Hegedus ,  Christopher Horvath ,  Gordon S. Scholler ,  Alan W. Berg

发明人： Ronald M. Kurtz ,  Tibor Juhasz ,  Peter Goldstein ,  Imre Hegedus ,  Christopher Horvath ,  Gordon S. Scholler ,  Alan W. Berg

IPC分类号： A61F9/007 ,  A61F9/01 ,  A61F9/008

CPC分类号： A61F9/008 ,  A61F9/00827 ,  A61F9/00836 ,  A61F2009/00872 ,  A61F2009/00897

摘要： A method and system for improved material processing using a laser beam. The method and system includes directing a laser beam above, at or below the surface of the material in one or more preferred patterns and with preferred laser pulse characteristics specific to the material to reduce or mitigate the accumulation or effects of gas, debris, fluid, or other by-products of photodisruption either at the location where additional laser pulses are being placed or in other sensitive locations in the material.

摘要翻译： 一种使用激光束改进材料处理的方法和系统。 该方法和系统包括以一种或多种优选图案将激光束引导到材料表面上方或下方，并且具有对材料特有的优选激光脉冲特性，以减少或减轻气体，碎片，流体， 或者在其他激光脉冲被放置的位置处或在材料中的其它敏感位置的光致破坏的其他副产物。

公开(公告)号：US06623476B2

公开(公告)日：2003-09-23

申请号：US09834979

申请日：2001-04-13

申请人： Tibor Juhasz ,  Ronald M. Kurtz ,  Carlos G. Suarez

发明人： Tibor Juhasz ,  Ronald M. Kurtz ,  Carlos G. Suarez

IPC分类号： A61B1820

CPC分类号： A61F9/009 ,  A61F2009/00872

摘要： A disposable lens for reconfiguring the cornea of an eye for ophthalmic laser surgery includes a lens which has a flat anterior surface that is formed opposite a contact surface. A skirt surrounds the contact surface and extends outwardly therefrom to define a chamber. The skirt is formed with a groove which creates a suction channel between the skirt and the contact surface in the chamber. In its operation, the lens is positioned over the cornea and a vacuum pump is selectively activated to create a partial vacuum in the suction channel. Due to this partial vacuum, the cornea is drawn into the chamber where it is urged against the contact surface of the lens. The result of this is that the cornea is flattened into a configuration where the introduction of spherical aberration and coma into a light beam passing into the cornea is reduced or eliminated.

摘要翻译： 用于重新配置用于眼科激光手术的眼睛角膜的一次性透镜包括具有与接触表面相对形成的平坦前表面的透镜。 裙部围绕接触表面并从其向外延伸以限定腔室。 裙部形成有凹槽，其在裙部和腔室中的接触表面之间产生吸入通道。 在其操作中，透镜位于角膜上方，并且选择性地激活真空泵以在吸入通道中产生部分真空。 由于这种部分真空，角膜被拉入腔室中，其被迫抵靠透镜的接触表面。 其结果是，角膜被平坦化成将通过角膜的光束引入球面像差和昏迷的结构减少或消除。

公开(公告)号：US09095414B2

公开(公告)日：2015-08-04

申请号：US13919547

申请日：2013-06-17

申请人： James V. Jester ,  Tibor Juhasz ,  Donald J. Brown ,  Dongyui Chai ,  Moritz Winkler

发明人： James V. Jester ,  Tibor Juhasz ,  Donald J. Brown ,  Dongyui Chai ,  Moritz Winkler

IPC分类号： A61B18/20 ,  A61F9/008 ,  A61F9/01 ,  A61N5/06

CPC分类号： A61F9/00802 ,  A61F9/008 ,  A61F9/00804 ,  A61F9/00825 ,  A61F2009/00872 ,  A61F2009/00893 ,  A61F2009/00895 ,  A61N5/062

摘要： The embodiments include method of nonlinear optical photodynamic therapy of tissue including the steps of providing pulsed infrared laser light for two-photon excited fluorescence tissue exposure, and selectively focusing the pulsed infrared laser light within the tissue at a focal plane to activate a photosensitizing agent to generate free radicals within a highly resolved axial and lateral spatial domain in the tissue. The invention is also directed to an apparatus for performing nonlinear optical photodynamic therapy of tissue including a pulsed infrared laser for providing two-photon excited fluorescence beam tissue exposure, a scanner for selectively and controllably moving the tissue and the beam relative to each other, and optics for selectively focusing the pulsed infrared laser light within the tissue at a point in a focal plane to activate a photosensitizing agent to generate free radicals within a highly resolved axial and lateral spatial domain in the tissue.

摘要翻译： 实施例包括组织的非线性光学光动力学治疗方法，包括以下步骤：为双光子激发荧光组织暴露提供脉冲红外激光，并且将聚焦平面上的组织内的脉冲红外激光选择性聚焦以激活光敏剂 在组织中高度分辨的轴向和横向空间结构域内产生自由基。 本发明还涉及一种用于执行包括用于提供双光子激发的荧光束组织暴露的脉冲红外激光的组织的非线性光学光学治疗的装置，用于选择性地和可控地移动组织和束相对于彼此的扫描仪，以及 用于选择性地将脉冲红外激光在聚焦平面中的一个点聚焦在组织内以激活光敏剂以在组织内的高度分辨的轴向和横向空间域内产生自由基的光学元件。