公开(公告)号：US11013595B2

公开(公告)日：2021-05-25

申请号：US16100601

申请日：2018-08-10

Applicant: Edwards Lifesciences Corporation

Inventor： Tamir S. Levi ,  Giolnara Pinhas ,  Liraz Marom ,  Elena Sherman ,  Noam Mizrahi ,  Delfin Rafael Ruiz ,  Sandip Vasant Pawar ,  Liron Tayeb

IPC: A61F2/24 ,  A61F2/00

Abstract: An implantable prosthetic valve that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration includes an annular frame having an inflow end, an outflow end, and a longitudinal axis. A leaflet structure is positioned within the frame and secured thereto, and a sealing element is secured to the frame. The sealing element includes a first woven portion extending circumferentially around the frame. The first woven portion includes a plurality of interwoven filaments. The sealing element further includes a second woven portion extending circumferentially around the frame and spaced apart from the first woven portion along the longitudinal axis of the frame. At least a portion of the filaments exit the weave of the first woven portion and form loops extending radially outwardly from the frame.

公开(公告)号：US20240366371A1

公开(公告)日：2024-11-07

申请号：US18777392

申请日：2024-07-18

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Michael Bukin ,  Giolnara Pinhas ,  Elena Sherman ,  Nikolai Gurovich

IPC: A61F2/24

Abstract: Sealing members for an outer skirt of a prosthetic heart valve are disclosed. As one example, a prosthetic heart valve can include an annular frame, a plurality of leaflets arranged within an interior of the frame, and an outer skirt disposed around an outer surface of the frame. The outer skirt can comprise at least one folded portion and stitches extending through the folded portion to form a radially protruding rib.

公开(公告)号：US20240261090A1

公开(公告)日：2024-08-08

申请号：US18596062

申请日：2024-03-05

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Ilan Tamir ,  Arie Tylis ,  Ofir Witzman ,  Noam Nir ,  Michal Aliza Ruchelsman ,  Giolnara Pinhas ,  Sirous Darabian ,  Travis Zenyo Oba

IPC: A61F2/24 ,  A61L27/04 ,  A61L27/36

CPC classification number: A61F2/2409 ,  A61F2/2418 ,  A61L27/04 ,  A61L27/3625 ,  A61F2/2412 ,  A61F2/2436 ,  A61F2220/0008 ,  A61F2220/0075 ,  A61F2230/0093 ,  A61F2250/0018 ,  A61F2250/0039 ,  A61F2250/0063 ,  A61L2430/20

Abstract: A replacement valve prosthesis includes a support structure and a valve body having three flexible leaflets. The support structure preferably includes an internal valve frame and an external sealing frame. The valve frame supports the flexible leaflets. The sealing frame is adapted to conform to the shape of the native heart valve annulus. The sealing frame may be coupled to an inlet end of the valve frame, an outlet end of the valve frame, or both. A plurality of anchors is coupled to the outlet end of the valve frame. The anchors extend radially outwardly for placement behind native leaflets. The prosthesis preferably includes a skirt disposed along an exterior of the external sealing frame. The prosthesis is collapsible for delivery into the heart via a delivery catheter. The prosthesis is configured to self-expand for deployment in the heart when released from the delivery catheter.

公开(公告)号：US20210275296A1

公开(公告)日：2021-09-09

申请号：US17327608

申请日：2021-05-21

Applicant: Edwards Lifesciences Corporation

Inventor： Tamir S. Levi ,  Giolnara Pinhas ,  Liraz Marom ,  Elena Sherman ,  Noam Mizrahi ,  Delfin Rafael Ruiz ,  Sandip Vasant Pawar ,  Liron Tayeb

IPC: A61F2/24 ,  A61F2/00

Abstract: An implantable prosthetic valve that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration includes an annular frame having an inflow end, an outflow end, and a longitudinal axis. A leaflet structure is positioned within the frame and secured thereto, and a sealing element is secured to the frame. The sealing element includes a first woven portion extending circumferentially around the frame. The first woven portion includes a plurality of interwoven filaments. The sealing element further includes a second woven portion extending circumferentially around the frame and spaced apart from the first woven portion along the longitudinal axis of the frame. At least a portion of the filaments exit the weave of the first woven portion and form loops extending radially outwardly from the frame.

公开(公告)号：US20250064584A1

公开(公告)日：2025-02-27

申请号：US18942285

申请日：2024-11-08

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Michael Bukin ,  Nikolai Gurovich ,  Elena Sherman ,  Anatoly Dvorsky ,  Giolnara Pinhas

IPC: A61F2/24

Abstract: A prosthetic heart valve can include a radially expandable and compressible annular frame, a valvular structure, and a commissure cover. The frame can include a plurality of struts defining the annular frame, and a plurality of commissure support structures each defining a commissure opening positioned along a circumference of the annular frame. The valvular structure can be mounted within the frame, the valvular structure including a plurality of commissures each extending radially through a respective commissure opening to attach the valvular structure to the frame, each commissure having an outflow edge that extends from a radial outer surface of the frame. The commissure cover can be disposed at least partially over the outflow edge of the commissure and can define a ramped surface that extends from the radial outer surface of the frame to a radial outer surface of the commissure.

公开(公告)号：US20230277306A1

公开(公告)日：2023-09-07

申请号：US18195808

申请日：2023-05-10

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Tamir S. Levi ,  Giolnara Pinhas ,  Liraz Marom ,  Elena Sherman ,  Noam Mizrahi ,  Delfin Rafael Ruiz ,  Sandip Vasant Pawar ,  Liron Tayeb

IPC: A61F2/24 ,  A61F2/00

CPC classification number: A61F2/2415 ,  A61F2/0077 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2210/0076 ,  A61F2230/0069 ,  A61F2250/0069

Abstract: An implantable prosthetic valve that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration includes an annular frame having an inflow end, an outflow end, and a longitudinal axis. A leaflet structure is positioned within the frame and secured thereto, and a sealing element is secured to the frame. The sealing element includes a first woven portion extending circumferentially around the frame. The first woven portion includes a plurality of interwoven filaments. The sealing element further includes a second woven portion extending circumferentially around the frame and spaced apart from the first woven portion along the longitudinal axis of the frame. At least a portion of the filaments comprise a hydrophilic surface treatment.

公开(公告)号：US20190046314A1

公开(公告)日：2019-02-14

申请号：US16100601

申请日：2018-08-10

Applicant: Edwards Lifesciences Corporation

Inventor： Tamir S. Levi ,  Giolnara Pinhas ,  Liraz Marom ,  Elena Sherman ,  Noam Mizrahi ,  Delfin Rafael Ruiz ,  Sandip Vasant Pawar ,  Liron Tayeb

IPC: A61F2/24

Abstract: An implantable prosthetic valve that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration includes an annular frame having an inflow end, an outflow end, and a longitudinal axis. A leaflet structure is positioned within the frame and secured thereto, and a sealing element is secured to the frame. The sealing element includes a first woven portion extending circumferentially around the frame. The first woven portion includes a plurality of interwoven filaments. The sealing element further includes a second woven portion extending circumferentially around the frame and spaced apart from the first woven portion along the longitudinal axis of the frame. At least a portion of the filaments exit the weave of the first woven portion and form loops extending radially outwardly from the frame.