公开(公告)号：US11013600B2

公开(公告)日：2021-05-25

申请号：US16252890

申请日：2019-01-21

Applicant: Edwards Lifesciences Corporation

Inventor： Evan T. Schwartz ,  Sean Chow ,  Sandip Vasant Pawar ,  Darshin S. Patel ,  Chambory Chhe ,  Arpit Laddha ,  Ngoc Huong Thi Nguyen ,  Waina Michelle Chu ,  Yuanlong Du ,  Michael Bukin ,  Boaz Manash ,  Sara Haivatov ,  Tamir S. Levi

IPC: A61F2/24

Abstract: A prosthetic heart valve includes a frame having an inflow end and an outflow end, and defining a longitudinal axis. The prosthetic heart valve further includes a leaflet structure situated at least partially within the frame, and a covering disposed around the frame. The covering includes a first woven portion extending circumferentially around the frame and including a plurality of texturized strands or yarns extending along the longitudinal axis of the frame. The covering further includes a second woven portion extending circumferentially around the frame and spaced apart from the first woven portion along the longitudinal axis of the frame. The texturized strands extend along the longitudinal axis of the frame from the first woven portion to the second woven portion and form a floating portion between the first woven portion and the second woven portion.

公开(公告)号：US20240033079A1

公开(公告)日：2024-02-01

申请号：US18482636

申请日：2023-10-06

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Shahram Zamani ,  Waina Michelle Chu ,  Ziv Yohanan ,  Dikla Kersh

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2250/0018 ,  A61F2250/0037 ,  A61F2250/0036 ,  A61F2240/001

Abstract: Disclosed herein are implantable medical devices comprising a textile material comprising a first material and a second material having different stretchability and flexibility, where the first and the second materials are at least partially superposed and coupled to each other. The medical devices of the current disclosure can be implantable prosthetic valves. The valves of the present disclosure provide for a reduced crimped profile and improve PVL sealing. In addition, disclosed herein are methods of making the implantable medical devices.

公开(公告)号：US20210275303A1

公开(公告)日：2021-09-09

申请号：US17327575

申请日：2021-05-21

Applicant: Edwards Lifesciences Corporation

Inventor： Evan T. Schwartz ,  Sean Chow ,  Sandip Vasant Pawar ,  Darshin S. Patel ,  Chambory Chhe ,  Arpit Laddha ,  Ngoc Huong Thi Nguyen ,  Waina Michelle Chu ,  Yuanlong Du ,  Michael Bukin ,  Boaz Manash ,  Sara Tzadok (formerly Haivatov) ,  Tamir S. Levi

IPC: A61F2/24

Abstract: A prosthetic heart valve includes a frame having an inflow end and an outflow end, and defining a longitudinal axis. The prosthetic heart valve further includes a leaflet structure situated at least partially within the frame, and a covering disposed around the frame. The covering includes a first woven portion extending circumferentially around the frame and including a plurality of texturized strands or yarns extending along the longitudinal axis of the frame. The covering further includes a second woven portion extending circumferentially around the frame and spaced apart from the first woven portion along the longitudinal axis of the frame. The texturized strands extend along the longitudinal axis of the frame from the first woven portion to the second woven portion and form a floating portion between the first woven portion and the second woven portion.

公开(公告)号：US20180133000A1

公开(公告)日：2018-05-17

申请号：US15809915

申请日：2017-11-10

Applicant: Edwards Lifesciences Corporation

Inventor： Taylor Jacob Scheinblum ,  Mindy Lee Ann Black ,  Tamir S. Levi ,  Evan T. Schwartz ,  Waina Michelle Chu ,  Linda Thai ,  Hanoch Cohen-Tzemach ,  Michael Bukin

IPC: A61F2/24

CPC classification number: A61F2/2412 ,  A61F2/2403 ,  A61F2/2415 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/2433 ,  A61F2/2454 ,  A61F2/95 ,  A61F2002/9522 ,  B25B27/02

Abstract: Embodiments are provided of an assembly having a prosthetic valve, the prosthetic valve having a radially expandable and compressible annular frame, and a crimping accessory device, and methods for using the assembly in compressing the prosthetic valve. The frame includes an outer surface and an inner surface. A leaflet assembly is supported inside the annular frame. The leaflet assembly includes a plurality of leaflets, each having an inner surface and an outer surface. The crimping accessory device has a plurality of axially-extending fingers. At least a first finger of the plurality of fingers is disposed between the outer surface of a first leaflet of the plurality of leaflets, and at least a second finger of the plurality of fingers is disposed radially-inwardly of the inner surface of the first leaflet.

公开(公告)号：US20240398559A1

公开(公告)日：2024-12-05

申请号：US18803359

申请日：2024-08-13

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Waina Michelle Chu ,  Jian Lin Phan ,  Eric Michael Oberwise ,  Sergio Delgado ,  Lauren R. Freschauf ,  Wen Yan Chen

IPC: A61F2/24

Abstract: An implantable device or implant is configured to be positioned within a native heart valve to allow the native heart valve to form a more effective seal. In some examples, a plurality of sutures is employed to secure frame portions of the implantable device to a connector of the implantable device. Each of the sutures can be passed through one or more eyelets of the frame portions and the connector. In some examples, an implantable device includes an actuation cap having a flexible portion or a biasing element positioned between an end portion of the actuation cap and an anchor portion of the implantable device. The flexible portion or the biasing element flex or compress responsive to forces between the connector and the actuation cap.

公开(公告)号：US20240374386A1

公开(公告)日：2024-11-14

申请号：US18784810

申请日：2024-07-25

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Pablo Hernan Catania ,  Munir Hicham Eltal ,  Andrew John Akagawa ,  Robert Bowes ,  Waina Michelle Chu ,  Nicolas Schleiger ,  Tam Van Nguyen ,  Alena Lian Sim ,  Thanh Huyen Tran ,  Rupesh Gajanan Nawalakhe ,  Chris J. Okos ,  Eric Robert Dixon ,  Grant Matthew Stearns ,  Kevin Gantz ,  Daniel Bobo ,  Aric Daniel Stone

IPC: A61F2/24

Abstract: Delivery systems and methods of delivering devices or implants are disclosed. The devices or implants can be configured as valve repair devices or treatment devices have gripping members that are openable and closable to attach the device to leaflets of a native heart valve. The delivery systems are configured to position the device or implant and open and close the gripping members of the device or implant.

公开(公告)号：US12138155B2

公开(公告)日：2024-11-12

申请号：US17228446

申请日：2021-04-12

Applicant: Edwards Lifesciences Corporation

Inventor： Taylor Jacob Scheinblum ,  Mindy Lee Ann Black ,  Tamir S. Levi ,  Evan T. Schwartz ,  Waina Michelle Chu ,  Linda Thai ,  Hanoch Cohen-Tzemach ,  Michael Bukin

IPC: A61F2/24 ,  A61F2/95 ,  B25B27/02

Abstract: Embodiments are provided of an assembly having a prosthetic valve, the prosthetic valve having a radially expandable and compressible annular frame, and a crimping accessory device, and methods for using the assembly in compressing the prosthetic valve. The frame includes an outer surface and an inner surface. A leaflet assembly is supported inside the annular frame. The leaflet assembly includes a plurality of leaflets, each having an inner surface and an outer surface. The crimping accessory device has a plurality of axially-extending fingers. At least a first finger of the plurality of fingers is disposed between the outer surface of a first leaflet of the plurality of leaflets, and at least a second finger of the plurality of fingers is disposed radially-inwardly of the inner surface of the first leaflet.

公开(公告)号：US11872125B2

公开(公告)日：2024-01-16

申请号：US17659577

申请日：2022-04-18

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Nikolai Gurovich ,  Michael Bukin ,  Elena Sherman ,  Tamir S. Levi ,  Ziv Yohanan ,  Gil Senesh ,  Dikla Kersh ,  Alexey Tsypenyuk ,  Waina Michelle Chu ,  Alexander Barash

IPC: A61F2/24 ,  A61F2/90

CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2/2433 ,  A61F2/2412 ,  A61F2/90 ,  A61F2220/0075 ,  A61F2230/0023 ,  A61F2230/0052 ,  A61F2250/0003 ,  A61F2250/0039 ,  A61F2250/0069 ,  A61F2310/00017 ,  A61F2310/00029 ,  A61F2310/00059

Abstract: A system can include a delivery catheter comprising a balloon and an implantable prosthetic heart valve. The prosthetic valve can have a plastically expandable and compressible unitary frame comprising first, second, and third rows of angled struts that define two circumferentially extending rows of diamond-shaped cells that extend continuously around the frame, and a valvular structure comprising a plurality of leaflets. A cusp edge portion of each leaflet is connected to the frame by a skirt that is connected to and disposed between the frame and the cusp edge portions of the leaflets, the skirt being connected to consecutive struts in the first, second, and third rows of struts with sutures. The compressed prosthetic heart valve can be mounted around the balloon and radially expanded to the expanded configuration with the balloon inside a patient's body.

公开(公告)号：US20230277313A1

公开(公告)日：2023-09-07

申请号：US18316942

申请日：2023-05-12

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Nikolai Gurovich ,  Michael Bukin ,  Elena Sherman ,  Tamir S. Levi ,  Ziv Yohanan ,  Gil Senesh ,  Dikla Kersh ,  Alexey Tsypenyuk ,  Waina Michelle Chu ,  Alexander Barash

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2433 ,  A61F2/2409 ,  A61F2250/0069 ,  A61F2250/0003 ,  A61F2230/0052 ,  A61F2230/0023 ,  A61F2/2412 ,  A61F2/90

Abstract: A prosthetic heart valve can include a radially expandable and compressible frame having an inflow end, an outflow end, and a plurality of struts. The prosthetic valve can further include a valvular structure comprising a plurality of leaflets, each leaflet comprising a coaptation edge portion and a cusp edge portion. The cusp edge portion of each leaflet can be folded toward the outflow end of the frame along a bending axis and a reinforcing member extends along an outflow surface of the cusp edge portion along the bending axis. The prosthetic heart valve can include a plurality of connecting skirts, each disposed between the cusp edge portion of an adjacent leaflet and the frame. First stitching secures the reinforcing member and the connecting skirts to the cusp edge portions and second stitching secures the connecting skirts to selected struts of the frame.

公开(公告)号：US11096781B2

公开(公告)日：2021-08-24

申请号：US15664430

申请日：2017-07-31

Applicant: Edwards Lifesciences Corporation

Inventor： Nikolay Gurovich ,  Michael Bukin ,  Elena Sherman ,  Tamir S. Levi ,  Ziv Yohanan ,  Gil Senesh ,  Dikla Kersh ,  Alexey M. Tsypenyuk ,  Waina Michelle Chu ,  Alexander Barash

IPC: A61F2/24

Abstract: A prosthetic heart valve can include a radially collapsible and expandable annular frame having a plurality of struts defining openings. The prosthetic heart valve can further include a plurality of leaflets that regulate the flow of blood through the frame. The prosthetic heart valve can also include a sealing member mounted on the frame and having an inner layer and an outer layer. At least the outer layer is mounted on the outside of the frame, and the inner layer covers at least the openings in the frame between adjacent cusp portions of adjacent leaflets and the inner layer does not cover one or more openings in the frame at locations facing the outflow surfaces of the leaflets to permit retrograde blood to flow through the one or more uncovered openings in the frame and into space between the outer layer and the frame.