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公开(公告)号：US06548170B2
公开(公告)日：2003-04-15
申请号：US09909438
申请日：2001-07-19
申请人： Eric Perrier , Lysiane Tholon , Nabil Abdul Malak
发明人： Eric Perrier , Lysiane Tholon , Nabil Abdul Malak
IPC分类号： B32B516
CPC分类号： C09C3/10 , A61K8/0241 , A61K8/27 , A61K8/29 , A61K8/64 , A61K8/73 , A61K8/8123 , A61K2800/43 , A61K2800/622 , A61Q1/06 , A61Q17/04 , A61Q19/005 , A61Q19/06 , C01P2004/60 , C01P2004/80 , C09C1/043 , C09C1/24 , C09C1/346 , C09C1/3676 , C09C1/405 , Y10T428/2982 , Y10T428/2989 , Y10T428/2991 , Y10T428/2998
摘要： The present invention relates to water-insoluble solid particles, especially pigments, which characteristically are coated with at least one layer of at least one product resulting from the reaction between at least one molecule capable of becoming hydrated in contact with water and at least one lipophilic molecule. It further relates to cosmetic, pharmaceutical and agricultural compositions comprising such particles and to the manufacture and use of said particles.
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公开(公告)号：US20060188465A1
公开(公告)日：2006-08-24
申请号：US11174414
申请日：2005-07-01
申请人： Eric Perrier , Nabil Abdul-Malak , Julie Saget
发明人： Eric Perrier , Nabil Abdul-Malak , Julie Saget
IPC分类号： A61K8/73 , A61K31/765 , C08G63/91
CPC分类号： C08B37/0033 , A61K8/73 , A61Q1/06 , A61Q5/02 , A61Q19/00 , A61Q19/06 , A61Q19/10 , C07H3/02 , C07H3/04 , C07H3/06 , C08B11/193 , C08B11/20 , C08B15/005 , C08B15/10 , C08B30/18 , C08B31/003 , C08B31/006 , C08B33/00 , C08B35/00 , C08B37/00 , C08B37/0024 , C08B37/003 , C08B37/0039 , C08B37/0042 , C08B37/0072 , C08B37/0084 , C08B37/0087 , C08B37/009 , C08B37/0093 , C08B37/0096
摘要： The invention discloses a cross-linked polymer of at least one carbohydrate component comprising at least one primary alcohol function in particular for the manufacture of a composition which is intended to be applied onto the skin to obtain a tensing and/or toning effect.
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3.发明授权公开(公告)号：US07419688B2
公开(公告)日：2008-09-02
申请号：US11177698
申请日：2005-07-07
申请人： Eric Perrier , Nabil Abdul-Malak
发明人： Eric Perrier , Nabil Abdul-Malak
摘要： A method for tinting, for coloring skin, or for increasing the tanned appearance of skin comprising the use of an extract of a plant from the family of Compositae or Asteraceae, preferably an extract of chicory (Cichorium intybus L.), and a method of screening a plant for the manufacture of a cosmetic composition for coloring, particularly for tinting, at least one part of skin.
摘要翻译： 用于着色，皮肤着色或增加皮肤鞣制外观的方法，包括使用菊科或菊科植物的提取物，优选菊苣（Cichorium intybus L.）的提取物，以及 筛选植物以制造用于着色的化妆品组合物，特别是用于着色的至少一部分皮肤。
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公开(公告)号：US20100316743A1
公开(公告)日：2010-12-16
申请号：US12667872
申请日：2008-07-09
IPC分类号： A61K36/00 , A61K36/13 , A61K36/73 , A61K31/352 , A61K36/45 , A61K36/20 , A61K31/122 , A61K31/7048 , G01N33/68 , A61P3/10
CPC分类号： A61Q19/08 , A23L33/105 , A61K8/347 , A61K8/35 , A61K8/355 , A61K8/411 , A61K8/415 , A61K8/498 , A61K8/97 , A61K31/05 , A61K31/122 , A61K31/353 , A61K31/7004 , A61K36/15 , A61K36/45 , A61K36/48 , A61K36/52 , A61K36/70 , A61K36/708 , A61K36/73 , A61K36/734 , A61K36/76 , A61K36/77 , A61K36/889 , A61K36/90
摘要： The present invention relates to the use of an active substance that promotes the inhibition of the formation of AGEs, for preparing a composition to prevent and/or combat the reduction in elastic and plastic properties of tissues, and in particular of the skin, for inhibiting the formation of AGEs, or for preventing and/or combating glycation of proteins in the skin.The invention also relates to a method of screening such active substances.
摘要翻译： 本发明涉及促进AGEs形成抑制活性物质的用途，用于制备预防和/或防止组织，特别是皮肤的弹性和塑性特性降低的组合物，用于抑制 AGEs的形成，或用于预防和/或防治皮肤中蛋白质的糖基化。 本发明还涉及筛选这种活性物质的方法。
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5.发明申请公开(公告)号：US20060222619A1
公开(公告)日：2006-10-05
申请号：US11177698
申请日：2005-07-07
申请人： Eric Perrier , Nabil Abdul-Malak
发明人： Eric Perrier , Nabil Abdul-Malak
摘要： The invention discloses a method for tinting, for coloring skin, or for increasing the tanned appearance of skin comprising the use of an extract of a plant from the family of Compositae or Asteraceae, preferably an extract of chicory (Cichorium intybus L.), and a method of screening a plant for the manufacture of a cosmetic composition for coloring, particularly for tinting, at least one part of skin.
摘要翻译： 本发明公开了一种用于着色皮肤着色或增加皮肤鞣制外观的方法，其包括使用菊科或菊科植物提取物，优选菊粉（Cichorium intybus L.）的提取物，以及 筛选植物以制造用于着色的化妆品组合物的方法，特别是用于着色皮肤的至少一部分。
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6.发明授权Cross-linked polymer of carbohydrate, notably based on polysaccharides, and/or on oligosaccharides and/or on polyols 有权碳水化合物的交联聚合物，特别是基于多糖，和/或在寡糖和/或多元醇上公开(公告)号：US09133279B2
公开(公告)日：2015-09-15
申请号：US11174414
申请日：2005-07-01
申请人： Eric Perrier , Nabil Abdul-Malak , Julie Saget
发明人： Eric Perrier , Nabil Abdul-Malak , Julie Saget
IPC分类号： A61K31/765 , A61K8/73 , C08G63/91 , C08B37/00 , A61Q19/00 , C07H3/02 , C07H3/04 , C07H3/06 , C08B11/193 , C08B11/20 , C08B15/00 , C08B15/10 , C08B30/18 , C08B31/00 , C08B33/00 , C08B35/00 , C08B37/08 , A61Q1/06 , A61Q5/02 , A61Q19/06 , A61Q19/10
CPC分类号： C08B37/0033 , A61K8/73 , A61Q1/06 , A61Q5/02 , A61Q19/00 , A61Q19/06 , A61Q19/10 , C07H3/02 , C07H3/04 , C07H3/06 , C08B11/193 , C08B11/20 , C08B15/005 , C08B15/10 , C08B30/18 , C08B31/003 , C08B31/006 , C08B33/00 , C08B35/00 , C08B37/00 , C08B37/0024 , C08B37/003 , C08B37/0039 , C08B37/0042 , C08B37/0072 , C08B37/0084 , C08B37/0087 , C08B37/009 , C08B37/0093 , C08B37/0096
摘要： The invention discloses a cross-linked polymer of at least one carbohydrate component comprising at least one primary alcohol function in particular for the manufacture of a composition which is intended to be applied onto the skin to obtain a tensing and/or toning effect.
摘要翻译： 本发明公开了至少一种包含至少一种伯醇官能团的碳水化合物组分的交联聚合物，特别是用于制备旨在施用于皮肤以获得张紧和/或调色效果的组合物。
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7.发明申请Active principle which is capable of inducing the conversion of inactive TGFb-latent into active TGFb 审中-公开能够诱导无活性TGFb潜伏转化成活性TGFb的活性成分公开(公告)号：US20050271751A1
公开(公告)日：2005-12-08
申请号：US10966168
申请日：2004-10-04
IPC分类号： A61K8/96 , A61K8/00 , A61K8/64 , A61K8/97 , A61K8/98 , A61K35/60 , A61K35/64 , A61K36/00 , A61K36/18 , A61K36/23 , A61K36/48 , A61K36/484 , A61K36/60 , A61K36/73 , A61K36/75 , A61K36/81 , A61K36/889 , A61K36/899 , A61P17/00 , A61P19/00 , A61P43/00 , A61Q1/00 , A61Q1/04 , A61Q1/06 , A61Q1/10 , A61Q5/02 , A61Q19/00 , A61Q19/08 , A61K35/78
摘要： The invention relates to active principles which are capable of inducing the conversion of inactive TGFb-Latent into active TGFb. The invention relates in particular to the use of such an extract for the manufacture of a composition for increasing the concentration of active TGFb1 in the skin, notably in the dermis. The present invention also relates to the uses which are derived from said use, as well as to cosmetic or pharmaceutical compositions which comprise said extract.
摘要翻译： 本发明涉及能够诱导无活性TGFb潜伏转化成活性TGFb的活性成分。 本发明特别涉及这种提取物用于制备用于增加皮肤中活性TGFb1浓度，特别是真皮中的浓度的组合物的用途。 本发明还涉及从所述用途衍生的用途，以及包含所述提取物的化妆品或药物组合物。
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8.发明授权Substance for restoring normal co-expression and interaction between the LOX and NRAGE proteins 有权用于恢复LOX和NRAGE蛋白质之间的正常共表达和相互作用的物质公开(公告)号：US09308161B2
公开(公告)日：2016-04-12
申请号：US13455366
申请日：2012-04-25
申请人： Charbel Bouez , Claudine Gleyzal , Isabelle Orly , Valerie Andre , Pascal Sommer , Corinne Reymermier , Odile Damour , Eric Perrier
发明人： Charbel Bouez , Claudine Gleyzal , Isabelle Orly , Valerie Andre , Pascal Sommer , Corinne Reymermier , Odile Damour , Eric Perrier
IPC分类号： A61K36/00 , A61K8/97 , A61K36/17 , A61K36/185 , A61K36/48 , A61K36/54 , A61Q19/00 , A61Q19/08 , G01N33/50
CPC分类号： A61K8/97 , A61K9/0014 , A61K36/17 , A61K36/185 , A61K36/45 , A61K36/48 , A61K36/54 , A61K36/77 , A61K2800/596 , A61K2800/70 , A61Q19/00 , A61Q19/004 , A61Q19/08 , G01N33/5011 , A61K2300/00
摘要： The disclosed substance restores normal co-expression and interaction between the LOX and NRAGE proteins. Particularly, an effective amount of the substance that modulates the expression and/or activity of LOX of SEQ ID NO: 1 and/or that modulates the expression and/or activity of NRAGE of SEQ ID NO: 2, may be used for the manufacture of a composition for modulating the interaction between the LOX and NRAGE proteins to regulate the balance between the cellular phenomena of proliferation, differentiation and apoptosis, particularly in cases where the balance between these phenomena is disturbed, and especially in cases where the interaction between LOX and NRAGE is absent or altered. The invention makes it possible especially to treat and/or prevent skin ageing, lichen planus, graft-versus-host reaction (GVH), eczema, psoriasis and a cancer, particularly an epithelial cancer and more particularly a cutaneous epithelial cancer of basocellular or spinocellular type.
摘要翻译： 所公开的物质恢复LOX和NRAGE蛋白之间的正常共表达和相互作用。 特别地，有效量的调节SEQ ID NO：1的LOX的表达和/或活性的物质和/或调节SEQ ID NO：2的NRAGE的表达和/或活性的物质可用于制造 用于调节LOX和NRAGE蛋白之间相互作用的组合物，以调节增殖，分化和凋亡的细胞现象之间的平衡，特别是在这些现象之间的平衡受到干扰的情况下，特别是在LOX和 NRAGE不存在或改变。 本发明可以特别地治疗和/或预防皮肤老化，扁平苔藓，移植物抗宿主反应（GVH），湿疹，牛皮癣和癌症，特别是上皮癌，特别是基底细胞或脊髓细胞的皮肤上皮癌 类型。
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9.发明申请METHODS USEFUL IN STUDYING OR MODULATING SKIN OR HAIR PIGMENTATION, PLANT EXTRACTS FOR USE IN COMPOSITIONS AND COSMETIC CARE METHOD 有权用于研究或调理皮肤或毛发染色的方法，用于组合物和化妆品护理方法的植物提取物公开(公告)号：US20140044651A2
公开(公告)日：2014-02-13
申请号：US13797050
申请日：2013-03-12
申请人： Robin Kurfurst , Carine Nizard , Sylvianne Schnebert , Eric Perrier , Desmond J. Tobin , Suman K. Singh
发明人： Robin Kurfurst , Carine Nizard , Sylvianne Schnebert , Eric Perrier , Desmond J. Tobin , Suman K. Singh
CPC分类号： A61K8/97 , A61K8/606 , A61K36/11 , A61K36/48 , A61K36/60 , A61K36/80 , A61K36/899 , A61Q5/00 , A61Q5/08 , A61Q5/10 , A61Q19/02 , A61Q19/04 , G01N33/5044 , G01N2333/4712
摘要： The invention relates to methods useful in studying or modulating skin or hair pigmentation and to the use of plant extracts in compositions as well as to methods comprising the topical use of such compositions to reduce or to enhance skin or hair pigmentation.
摘要翻译： 本发明涉及可用于研究或调节皮肤或毛发色素沉着和组合物中植物提取物的使用的方法以及包括局部使用这种组合物以减少或增强皮肤或毛发色素沉积的方法。
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10.发明授权Methods useful in studying or modulating skin or hair pigmentation, plant extracts for use in compositions and cosmetic care method 有权用于研究或调节皮肤或毛发色素沉着的方法，用于组合物和美容护理方法的植物提取物公开(公告)号：US08409633B2
公开(公告)日：2013-04-02
申请号：US13063150
申请日：2009-09-09
申请人： Robin Kurfurst , Carine Nizard , Sylvianne Schnebert , Eric Perrier , Desmond J. Tobin , Suman K. Singh
发明人： Robin Kurfurst , Carine Nizard , Sylvianne Schnebert , Eric Perrier , Desmond J. Tobin , Suman K. Singh
CPC分类号： A61K8/97 , A61K8/606 , A61K36/11 , A61K36/48 , A61K36/60 , A61K36/80 , A61K36/899 , A61Q5/00 , A61Q5/08 , A61Q5/10 , A61Q19/02 , A61Q19/04 , G01N33/5044 , G01N2333/4712
摘要： The invention relates to methods useful in studying or modulating skin or hair pigmentation and to the use of plant extracts in compositions as well as to methods comprising the topical use of such compositions to reduce or to enhance skin or hair pigmentation.
摘要翻译： 本发明涉及可用于研究或调节皮肤或毛发色素沉着和组合物中植物提取物的使用的方法以及包括局部使用这种组合物以减少或增强皮肤或毛发色素沉积的方法。
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