Dryer and method for drying continuously conveyed products
    2.
    发明授权
    Dryer and method for drying continuously conveyed products 失效
    烘干机和连续输送产品的干燥方法

    公开(公告)号:US06557268B1

    公开(公告)日:2003-05-06

    申请号:US09743793

    申请日:2001-06-11

    IPC分类号: F26B504

    CPC分类号: F26B13/10 F26B13/001

    摘要: The invention relates to a dryer (1) for drying continuously conveyed products, e.g. a warp, comprising essentially a first dryer array (2) and a second dryer array (3). A passage (4) for passing through the product (W) is formed between the dryer arrays (2, 3). The second dryer array (3) is configured in such a way as to be able to move in relation to the first dryer array (2). When the dryer (1) is in stop position (S), the second dryer array (3) is disposed relative to the first dryer array (2) in such a way that the cross section of the passage (4) is bigger than in the operating position (B).

    摘要翻译: 本发明涉及一种干燥器(1),用于干燥连续输送的产品,例如, 翘曲,基本上包括第一干燥器阵列(2)和第二干燥器阵列(3)。 在干燥器阵列(2,3)之间形成有通过产品(W)的通道(4)。 第二干燥器阵列(3)被构造成能够相对于第一干燥器阵列(2)移动。 当干燥器(1)处于停止位置(S)时,第二干燥器阵列(3)相对于第一干燥器阵列(2)设置成使得通道(4)的横截面大于 操作位置(B)。

    Attachment of cells to surfaces
    5.
    发明申请
    Attachment of cells to surfaces 审中-公开
    细胞附着在表面

    公开(公告)号:US20060252152A1

    公开(公告)日:2006-11-09

    申请号:US10571193

    申请日:2004-10-05

    摘要: The present invention relates to a microcarrier onto the surface of which a cationic compound has been immobilised via a guanidine group. The microcarrier is capable of attachment of cells, e.g. via charge-based interaction, and is advantageously used as a support in the culture of cells. Said compound may comprise one or two amino acids, such as arginine (Arg) or a dipeptide. The invention also relates to a method of preparing a polycationic microcarrier, which method comprises to immobilise a compound that comprises at least one guanidine group to an epoxide-activated substrate.

    摘要翻译: 本发明涉及通过胍基固定有阳离子化合物的表面上的微载体。 微载体能够附着细胞,例如细胞。 通过基于电荷的相互作用,并且有利地用作细胞培养物中的载体。 所述化合物可以包含一个或两个氨基酸,例如精氨酸(Arg)或二肽。 本发明还涉及一种制备聚阳离子微载体的方法,该方法包括将包含至少一个胍基的化合物固定在环氧化物活化的底物上。

    Manufacturing process for porous material
    7.
    发明申请
    Manufacturing process for porous material 审中-公开
    多孔材料的制造工艺

    公开(公告)号:US20060025585A1

    公开(公告)日:2006-02-02

    申请号:US11224574

    申请日:2005-09-12

    IPC分类号: C08B37/00

    摘要: A method for the manufacture of a solid porous separation material based on a polysaccharide, said method comprising the steps of: (a) providing an aqueous solution (I) of a polysaccharide, (b) solidifying the solution, preferably by transforming the solution to a gel, and (c) optionally cross-linking the polysaccharide, with the proviso that, if step (c) is present, steps (b) and (c) may be carried out simultaneously. The method is characterised in that the polysaccharide provided in step (a) is modified by being inter-molecularly cross-linked to an extent such that the viscosity of solution (I) is at least 110%, preferably at least 200%, of the viscosity of an aqueous solution (II) of the corresponding polysaccharide which has not been inter-molecularly cross-linked and which is present in the same concentration as the inter-molecularly cross-linked polysaccharide is in solution (I).

    摘要翻译: 一种制备基于多糖的固体多孔分离材料的方法,所述方法包括以下步骤:(a)提供多糖的水溶液(I),(b)固化溶液,优选通过将溶液转化为 凝胶,和(c)任选地交联多糖,条件是如果存在步骤(c),则可以同时进行步骤(b)和(c)。 该方法的特征在于,步骤(a)中提供的多糖通过分子内交联以使溶液(I)的粘度为至少110%,优选至少200% 在溶液(I)中,未分子间交联并且与分子内交联的多糖以相同浓度存在的相应多糖的水溶液(II)的粘度是。

    Process for the production of a porous cross-linked polysaccharide gel and its use as a gel filtration media and in chromatography
    8.
    发明授权
    Process for the production of a porous cross-linked polysaccharide gel and its use as a gel filtration media and in chromatography 有权
    生产多孔交联多糖凝胶的方法及其作为凝胶过滤介质和色谱法的用途

    公开(公告)号:US06602990B1

    公开(公告)日:2003-08-05

    申请号:US09155995

    申请日:1999-05-11

    申请人: Hans Berg

    发明人: Hans Berg

    IPC分类号: C08B3704

    摘要: A process for the production of a porous cross-linked polysaccharide gel and a gel obtainable by the following steps: a) preparing a solution or dispersion of the polysaccharide; b) adding a bifunctional cross-linking agent having one active site and one inactive site to the solution or dispersion from step a); c) reacting hydroxylgroups of the polysaccharide with the active site of the cross-linking agent; d) forming a polysaccharide gel; e) activating the inactive site of the cross-linking agent; f) reacting the activated site from step e) with hydroxylgroups of the polysaccharide gel, whereby cross-linking of the gel takes place. The cross-linked polysaccharide gel obtained can further be cross-linked by conventional methods, one or several times.

    摘要翻译: 一种生产多孔交联多糖凝胶和凝胶的方法,可通过以下步骤获得:a)制备多糖的溶液或分散体; b)向来自步骤a)的溶液或分散体中加入具有一个活性位点和一个无活性位点的双功能交联剂; c)使多糖的羟基与交联剂的活性位点反应; d)形成多糖凝胶; e)活化交联剂的非活性位点; f)使来自步骤e)的活化部位与多糖凝胶的羟基反应,从而发生凝胶的交联。 获得的交联多糖凝胶可以通过常规方法进一步交联一次或数次。

    Purification of immunoglobulins
    9.
    发明授权
    Purification of immunoglobulins 有权
    免疫球蛋白的纯化

    公开(公告)号:US08728828B2

    公开(公告)日:2014-05-20

    申请号:US11315402

    申请日:2005-12-22

    IPC分类号: G01N33/543

    摘要: The present invention relates to a separation matrix comprised of porous particles to which antibody-binding protein ligands have been immobilized, wherein the ligand density is in the range of 5.0-10 mg/ml; the gel phase distribution coefficient of the particles expressed as Kav for a dextran of size 110 kDa is above 0.65 and the median particle diameter is between 65-84 μm. The carbohydrate material is preferably highly cross-linked agarose.

    摘要翻译: 本发明涉及由多孔颗粒组成的分离基质,抗体结合蛋白质配体已经固定在其上,其中配体密度在5.0-10mg / ml的范围内; 表示为大小为110kDa的葡聚糖的Kav的颗粒的凝胶相分布系数大于0.65,中值粒径在65-84μm之间。 碳水化合物材料优选是高度交联的琼脂糖。