Method of producing hierarchical porous beads
    5.
    发明授权
    Method of producing hierarchical porous beads 有权
    生产层状多孔珠的方法

    公开(公告)号:US07074335B2

    公开(公告)日:2006-07-11

    申请号:US10500677

    申请日:2002-12-17

    IPC分类号: B01D15/08

    摘要: The present invention is a method of producing porous beads, which comprises the steps of providing a first liquid phase comprising a bead matrix material and essentially edgy templating particle(s), said particle(s) being treated with a surface modifying agent; providing a second liquid phase which is immiscible with the first liquid phase; contacting the first phase and the second phase under conditions resulting in an emulsion of droplets comprised of the first liquid phase dispersed in the continuous second liquid phase; transforming the droplets to mesoporous beads by solidification of the liquid; and removing the templating particle(s) from the beads without causing any essential change of the surrounding bead, whereby hierarchical networks of pores are provided in the beads.

    摘要翻译: 本发明是一种生产多孔珠的方法,其包括以下步骤:提供包含珠粒基质材料和基本上前提的模板颗粒的第一液相,所述颗粒用表面改性剂处理; 提供与第一液相不混溶的第二液相; 在产生由分散在连续第二液相中的第一液相组成的液滴的乳液的条件下使第一相和第二相接触; 通过液体凝固将液滴转变成中孔珠粒; 并且从珠粒中除去模板颗粒,而不会引起周围珠粒的任何必需的变化,由此在珠粒中提供分级网孔。

    Attachment of cells to surfaces
    9.
    发明申请
    Attachment of cells to surfaces 审中-公开
    细胞附着在表面

    公开(公告)号:US20060252152A1

    公开(公告)日:2006-11-09

    申请号:US10571193

    申请日:2004-10-05

    摘要: The present invention relates to a microcarrier onto the surface of which a cationic compound has been immobilised via a guanidine group. The microcarrier is capable of attachment of cells, e.g. via charge-based interaction, and is advantageously used as a support in the culture of cells. Said compound may comprise one or two amino acids, such as arginine (Arg) or a dipeptide. The invention also relates to a method of preparing a polycationic microcarrier, which method comprises to immobilise a compound that comprises at least one guanidine group to an epoxide-activated substrate.

    摘要翻译: 本发明涉及通过胍基固定有阳离子化合物的表面上的微载体。 微载体能够附着细胞,例如细胞。 通过基于电荷的相互作用,并且有利地用作细胞培养物中的载体。 所述化合物可以包含一个或两个氨基酸,例如精氨酸(Arg)或二肽。 本发明还涉及一种制备聚阳离子微载体的方法,该方法包括将包含至少一个胍基的化合物固定在环氧化物活化的底物上。