Carbonate, carbamate, thiocarbonate dithiocarbonate and thiocarbomate derivatives useful as fungicides
    2.
    发明授权
    Carbonate, carbamate, thiocarbonate dithiocarbonate and thiocarbomate derivatives useful as fungicides 失效
    用作杀真菌剂的碳酸盐,氨基甲酸盐,硫代碳酸二酯和硫代碳酸盐衍生物

    公开(公告)号:US06465457B1

    公开(公告)日:2002-10-15

    申请号:US08211390

    申请日:1994-08-18

    IPC分类号: A01N4710

    摘要: Fungicidal compounds of formula (I): wherein W is CH3O.CH═CCO2CH3, CH3ON═CCONR3R4 or CH3ON═CCO2CH3 and stereoisomers thereof; n is 0 or 1; X is oxygen or sulphur; Z is NR1; R1 is hydrogen or alkyl optionally substituted with halogen, C1-6 alkoxy, C2-6 alkenyl, C2-6 alkynyl, C3-6 cycloalkyl or aryl; R2 is alkyl, haloalkyl, alkenyl, alkynyl, alkoxycarbonyl(C1-4)alkyl, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted aryl(C1-4)alkyl, optionally substituted heteroaryl(C1-4)alkyl, optionally substituted aryloxy(C1-4)alkyl, optionally substituted heteroaryloxy(C1-4)alkyl, optionally substituted aryloxy (C2-4)alkenyl, optionally substituted heteroaryloxy(C2-4) alkenyl, optionally substituted aryl(C2-4)alkenyl, optionally substituted heteroaryl(C2-4) alkenyl, optionally substituted arylcarbonyl(C1-4)alkyl, optionally substituted heteroarylcarbonyl(C1-4)alkyl, optionally substituted aryloxycarbonyl(C1-4)alkyl, optionally substituted heteroaryloxycarbonyl(C1-4)alkyl or —COR5; or R1 and R2 together form an optionally substituted 4-, 5- or 6-membered heterocyclic ring system; R3 and R4 are independently hydrogen or methyl; and R5 is optionally substituted heteroaryl or optionally substituted aryl; and processes for preparing, compositions containing and methods of combating fungi using compounds of formula (I).

    摘要翻译: 式(I)的杀真菌化合物:其中W是CH 3 O,CH = CCO 2 CH 3,CH 3 ON = CCONR 3 R 4或CH 3 ON = CCO 2 CH 3及其立体异构体; n为0或1; X是氧或硫; Z是NR1; R 1是氢或任选被卤素,C 1-6烷氧基,C 2-6烯基,C 2-6炔基,C 3-6环烷基或芳基取代的烷基; 任选取代的芳基,任选取代的芳基(C 1-4)烷基,任选取代的杂芳基(C 1-4)烷基,任选取代的芳氧基(C 1-4)烷基, C 1-4)烷基,任选取代的杂芳氧基(C 1-4)烷基,任选取代的芳氧基(C 2-4)烯基,任选取代的杂芳氧基(C 2-4)烯基,任选取代的芳基(C 2-4)烯基,任选取代的杂芳基 任选取代的芳基羰基(C 1-4)烷基,任选取代的芳基羰基(C 1-4)烷基,任选取代的芳氧基羰基(C 1-4)烷基,任选取代的杂芳氧羰基(C 1-4)烷基或-COR 5; 或R 1和R 2一起形成任选取代的4-,5-或6-元杂环系统; R3和R4独立地是氢或甲基; 且R 5为任选取代的杂芳基或任选取代的芳基; 和制备方法,含有组合物的方法和使用式(I)化合物对抗真菌的方法。

    Bicyclic amine derivatives
    9.
    发明授权
    Bicyclic amine derivatives 失效
    双环胺衍生物

    公开(公告)号:US06291474B1

    公开(公告)日:2001-09-18

    申请号:US09635879

    申请日:2000-08-10

    IPC分类号: A61K31435

    摘要: The invention provides a compound of formula (I): wherein A is CH═CH; Ar is an optionally substituted 5-membered heterocyclic ring system containing from 1 to 3 heteroatoms individually selected from nitrogen, oxygen and sulfur atoms, and at least one unsaturation (double bond) between adjacent atoms in the ring, said heterocyclic ring being optionally fused to a benzene ring, and R′ is hydrogen, cyano, hydroxy, alkyl, alkoxy, amino, nitro, isocyanato, acylamino, hydroxyalkyl, optionally substituted heteroaryl, alkoxyalkyl, haloalkyl, halohydroxyalkyl, aralkyloxyalkyl, acyloxyalkyl, amidoximido, sulfonyloxyalkyl, aminoalkyl, alkoxycarbonylamino, acylaminoalkyl, cyanoalkyl, imino, formyl, acyl or carboxylic acid or an ester or amide thereof, or alkenyl or alkynyl either of which is optionally substituted by halogen, alkoxy, cycloalkyl, optionally substituted aryl, optionally substituted heteroaryl or cyano; or an acid addition salt, quaternary ammonium salt or N-oxide derived therefrom; an insecticidal, acaricidal or nematicidal composition comprising a compound of formula (I) and a suitable carrier or diluent therefor; a method of combating and controlling insect, acarine or nematode pests at a locus which comprises treating the pests or the locus of the pests with an effective amount of a compound of formula (I) or a composition as hereinbefore described.

    摘要翻译: 本发明提供式(I)化合物:其中A为CH = CH; Ar是任选取代的5元杂环系统,其含有1-3个分别选自氮,氧和硫原子的杂原子,以及环中相邻原子之间的至少一个不饱和键(双键),所述杂环任选地与 苯环,R'是氢,氰基,羟基,烷基,烷氧基,氨基,硝基,异氰酸根合,酰氨基,羟基烷基,任选取代的杂芳基,烷氧基烷基,卤代烷基,卤代羟烷基,芳烷氧基烷基,酰氧基烷基,酰氨基亚氨基,磺酰氧基烷基,氨基烷基,烷氧基羰基氨基, 酰基氨基烷基,氰基烷基,亚氨基,甲酰基,酰基或羧酸或其酯或酰胺,或任选被卤素,烷氧基,环烷基,任选取代的芳基,任选取代的杂芳基或氰基取代的链烯基或炔基; 或由其衍生的酸加成盐,季铵盐或N-氧化物; 杀虫杀螨或杀线虫组合物,其包含式(I)化合物及其合适的载体或稀释剂; 一种防治昆虫,螨虫或线虫害虫的方法,包括用有效量的式(I)化合物或上述组合物处理害虫或害虫的场所。

    Bicyclic amines
    10.
    发明授权
    Bicyclic amines 失效
    双环胺

    公开(公告)号:US5922732A

    公开(公告)日:1999-07-13

    申请号:US651182

    申请日:1996-05-24

    摘要: A compound of formula (I): ##STR1## wherein R.sup.1 represents a group of formula (A) where each of W, X, Y and Z and Z represents either a group CR or the nitrogen atom, provided that not more than two of W, X, Y and Z represent the nitrogen atom and where each R present is independently selected from hydrogen and halogen atoms and cyano, amino, hydrazino, acylamino, hydroxy, alkyl, hydroxyalkyl, alkoxy, haloalkyl, haloalkoxy, alkenyl, alkenyloxy, alkoxyalkenyl, alkynyl, carboxylic acyl, alkoxycarbonyl, aryl and heterocyclyl groups, said groups comprising up to 6 carbon atoms, and wherein R.sup.2 represents hydrogen or cyano or a group selected from alkyl, aryl, heteroaryl, aralkyl, heteroarylalkyl, alkenyl, aralkenyl, alkynyl, alkoxycarbonyl, alkanesulfonyl, arenesulfonyl, alkanyloxycarbonyl, aralkyloxycarbonyl, aryloxycarbonyl, heterocyclylalkyl, carbamyl or dithiocarboxyl groups, said groups comprising from 1 to 15 carbon atoms, said groups being optionally substituted with one or more substituents selected from, halogen, cyano, carboxyl, carboxylic acyl, carbamyl, alkoxycarbonyl, alkoxy, alkylenedioxy, hydroxy, nitro, haloalkyl, alkyl, amino, acylamino, imidate and phosphonato groups; and acid addition salts and quaternary ammonium salts and N-oxides derived therefrom. The compounds are useful as insecticides.

    摘要翻译: 式(I)的化合物:其中R 1表示式(A)的基团,其中W,X,Y和Z和Z各自表示基团CR或氮原子,条件是不大于2个W,X ,Y和Z代表氮原子,其中每个R独立地选自氢和卤素原子和氰基,氨基,肼基,酰氨基,羟基,烷基,羟基烷基,烷氧基,卤代烷基,卤代烷氧基,烯基,烯氧基,烷氧基烯基,炔基, 羧基酰基,烷氧基羰基,芳基和杂环基,所述基团包含至多6个碳原子,并且其中R 2表示氢或氰基或选自烷基,芳基,杂芳基,芳烷基,杂芳基烷基,烯基,芳烯基,炔基,烷氧基羰基,链烷磺酰基 ,芳基磺酰基,烷氧基羰基,芳烷氧基羰基,芳氧基羰基,杂环基烷基,氨基甲酰基或二硫代羧基,​​所述基团包含1至15个碳原子,所述基团任选被一个或多个取代基 选自卤素,氰基,羧基,羧基酰基,氨基甲酰基,烷氧基羰基,烷氧基,亚烷基二氧基,羟基,硝基,卤代烷基,烷基,氨基,酰氨基,亚胺基和膦酸酯基。 和酸加成盐和季铵盐和由其衍生的N-氧化物。 这些化合物可用作杀虫剂。