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    Oscillation apparatus and methods for multi-analyte homogeneous fluoro-immunoassays
    1.
    发明授权
    Oscillation apparatus and methods for multi-analyte homogeneous fluoro-immunoassays 失效
    用于多分析物均匀荧光免疫测定的振荡装置和方法

    公开(公告)号：US06242267B1

    公开(公告)日：2001-06-05

    申请号：US09142946

    申请日：1998-09-18

    申请人： James N. Herron ,  Douglas A. Christensen ,  Scott D. Miles

    发明人： James N. Herron ,  Douglas A. Christensen ,  Scott D. Miles

    IPC分类号： G01N33552

    CPC分类号： G01N33/54386 ,  G01N33/54373 ,  Y10S435/808 ,  Y10S436/807

    摘要： An apparatus and method for rapidly analyzing samples for analytes of interest by an homogeneous immunofluorescence assay. The apparatus includes a sample test cartridge having a high control sample section, a low control sample section, and at least one test sample section. Each of these sections contain at least one pre-loaded reagent housed in a well within the cartridge wherein the low control sample section contains a known low amount of an analyte of interest and the high control sample section contains a known high amount of an analyte of interest. The cartridge includes a biosensor comprising a planar waveguide having first and second parallel plane surfaces and an edge extending between them, the edge having a receiving region for receiving a light beam. Each of the high control sample section, the low control sample section, and the test sample control sections have a well which includes a waveguide surface, wherein the contents of each section contacts capture molecules immobilized on the waveguide surface. The capture molecules are configured to specifically bind a chosen analyte and fluoresce when interacting with light passing through the waveguide surface. The concentration of said analyte of interest in said sample fluid is determined by a comparison of intensities of fluorescence of between said capture molecule areas of said sample capture molecule well, said low control capture molecule well, and said high control capture molecule well.

    摘要翻译： 用于通过均匀免疫荧光测定快速分析感兴趣的分析物的样品的装置和方法。 该装置包括具有高控制样品部分，低对照样品部分和至少一个测试样品部分的样品测试盒。 这些部分中的每一个包含至少一个预先加载的试剂，其容纳在筒内的孔中，其中低对照样品部分含有已知的低量感兴趣的分析物，并且高对照样品部分含有已知的大量分析物 利益。 所述盒包括生物传感器，所述生物传感器包括具有第一和第二平行平面的平面波导和在它们之间延伸的边缘，所述边缘具有用于接收光束的接收区域。 高控制采样部分，低控制样品部分和测试样品控制部分中的每一个具有包括波导表面的阱，其中每个部分的内容物接触固定在波导表面上的捕获分子。 捕获分子被配置为特异性地结合所选择的分析物并且当与通过波导表面的光相互作用时发出荧光。 通过比较所述样品捕获分子阱的所述捕获分子区域，所述低对照捕获分子阱和所述高对照捕获分子阱之间的荧光强度来确定所述样品流体中所述目标分析物的浓度。

    SLEEP SURFACE INSERT SYSTEM AND METHOD THEREOF
    4.
    发明申请
    SLEEP SURFACE INSERT SYSTEM AND METHOD THEREOF 审中-公开
    休眠表面插入系统及其方法

    公开(公告)号：US20130326811A1

    公开(公告)日：2013-12-12

    申请号：US13907781

    申请日：2013-05-31

    申请人： Scott D. Miles ,  Dana L. Miles

    发明人： Scott D. Miles ,  Dana L. Miles

    IPC分类号： A47D15/00

    CPC分类号： A61B5/4818 ,  A47C7/744 ,  A47C21/04 ,  A47C21/044 ,  A47D7/00 ,  A47D9/00 ,  A47D15/001 ,  A61B5/0205 ,  A61B5/4836 ,  A61B5/6892 ,  A61B2503/04 ,  A61B2562/0247

    摘要： A sleep surface insert system and method for positioning under, for example, an infant on a sleep surface. The sleep surface insert system includes an insert and a blower system. The insert includes a top liner and a bottom liner. The top liner and bottom liner define first and a second hollow spaces therebetween. Further, the top liner includes first and second pores such that the first pores extend through the top liner from the first hollow space and the second pores extend through the top liner from the second hollow space. In addition, the blower system is configured to provide air flow into the first and second hollow spaces defined in the insert such that the air flow is configured to flow into the insert and out of at least one of the first pores and the second pores.

    摘要翻译： 一种用于定位在例如睡眠表面上的婴儿的睡眠表面插入系统和方法。 睡眠表面插入系统包括插入件和鼓风机系统。 插入件包括顶衬和底衬。 顶部衬套和底部衬套在其间限定第一和第二中空空间。 此外，顶部衬垫包括第一和第二孔，使得第一孔从第一中空空间延伸穿过顶部衬垫，并且第二孔从第二中空空间延伸穿过顶部衬垫。 此外，鼓风机系统构造成将空气流提供到限定在插入件中的第一和第二中空空间中，使得空气流被配置成流入插入件并且从至少一个第一孔和第二孔排出。

    APPARATUS AND METHODS FOR OCCLUDING A FALLOPIAN TUBE
    6.
    发明申请
    APPARATUS AND METHODS FOR OCCLUDING A FALLOPIAN TUBE 审中-公开
    装置和方法，用于遮挡倒伏管

    公开(公告)号：US20100006105A1

    公开(公告)日：2010-01-14

    申请号：US12169506

    申请日：2008-07-08

    申请人： Phillip J. Carter ,  Richard J. Linder ,  Randall K. Jones ,  Scott D. Miles ,  Clark C. Davis ,  Daryl R. Edmiston ,  DeWayne C. Fox

    发明人： Phillip J. Carter ,  Richard J. Linder ,  Randall K. Jones ,  Scott D. Miles ,  Clark C. Davis ,  Daryl R. Edmiston ,  DeWayne C. Fox

    IPC分类号： A61F6/22 ,  A61B17/425

    CPC分类号： A61F6/225

    摘要： The present invention is directed to various embodiments of medical devices and methods for occluding a fallopian tube for contraception and permanent sterilization. In one embodiment, the medical device includes an outer member, an inner member and a tissue growth member. The outer member includes an outer surface and an inner surface, wherein the inner surface defines a bore in the outer member. The inner member is configured to be positioned within the bore of the outer member. The tissue growth member is attached to the outer surface of the outer member and is configured to induce tissue growth thereto. With this arrangement, the medical device can be implanted within the fallopian tube and serve as a permanent occluding device therein. If desired, the medical device can be partially removed from the fallopian tube to restore the ability for conception.

    摘要翻译： 本发明涉及用于闭塞输卵管用于避孕和永久灭菌的医疗装置和方法的各种实施例。 在一个实施例中，医疗装置包括外部构件，内部构件和组织生长构件。 外部构件包括外表面和内表面，其中内表面在外构件中限定孔。 内部构件构造成定位在外部构件的孔内。 组织生长构件附接到外部构件的外表面并且构造成诱导组织生长。 利用这种布置，医疗装置可以植入输卵管内并用作其中的永久性闭塞装置。 如果需要，医疗设备可以部分地从输卵管中移除以恢复受孕的能力。