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公开(公告)号：US20120053517A1
公开(公告)日：2012-03-01
申请号：US13289490
申请日：2011-11-04
申请人： John Chen , Raed Rizq , Kent Harrison , Daniel Horn , Gordon Kocur , Tracee Eidenschink , Ben Arcand , Derek Sutermeister , Jay Rassat , Colm McGuiness , Wendy Naimark , Ruth Cheng
发明人： John Chen , Raed Rizq , Kent Harrison , Daniel Horn , Gordon Kocur , Tracee Eidenschink , Ben Arcand , Derek Sutermeister , Jay Rassat , Colm McGuiness , Wendy Naimark , Ruth Cheng
IPC分类号： A61M25/10
CPC分类号： A61M25/1029 , A61L29/085 , A61L29/16 , A61L2300/416 , A61M25/0045 , A61M25/10 , A61M2025/0056 , A61M2025/1031 , A61M2025/105 , B29L2009/005 , C08L53/02
摘要： Catheter devices having an expandable balloon for delivering a therapeutic agent to a body site. In one aspect, one or more sheaths are disposed around the balloon with the therapeutic agent being disposed within the sheath, being disposed over the sheath, being contained in the space between the sheath and the balloon, or being otherwise associated with the sheath. In another aspect, the balloon includes a micro-electromechanical system (MEMS) for drug delivery.
摘要翻译： 具有用于将治疗剂递送到身体部位的可膨胀气囊的导管装置。 在一个方面，一个或多个护套设置在球囊周围，治疗剂设置在护套内，设置在护套上，被包含在护套和气囊之间的空间中，或者与护套相关联。 另一方面，气囊包括用于药物递送的微机电系统（MEMS）。
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公开(公告)号：US20090227948A1
公开(公告)日：2009-09-10
申请号：US12399386
申请日：2009-03-06
申请人： John Chen , Raed Rizq , Kent Harrison , Daniel Horn , Gordon Kocur , Tracee Eidenschink , Ben Arcand , Derek Sutermeister , Jay Rassat , Colm McGuiness , Wendy Naimark , Ruth Cheng
发明人： John Chen , Raed Rizq , Kent Harrison , Daniel Horn , Gordon Kocur , Tracee Eidenschink , Ben Arcand , Derek Sutermeister , Jay Rassat , Colm McGuiness , Wendy Naimark , Ruth Cheng
CPC分类号： A61M25/1029 , A61L29/085 , A61L29/16 , A61L2300/416 , A61M25/0045 , A61M25/10 , A61M2025/0056 , A61M2025/1031 , A61M2025/105 , B29L2009/005 , C08L53/02
摘要： Catheter devices having an expandable balloon for delivering a therapeutic agent to a body site. In one aspect, one or more sheaths are disposed around the balloon with the therapeutic agent being disposed within the sheath, being disposed over the sheath, being contained in the space between the sheath and the balloon, or being otherwise associated with the sheath. In another aspect, the balloon includes a micro-electromechanical system (MEMS) for drug delivery.
摘要翻译： 具有用于将治疗剂递送到身体部位的可膨胀气囊的导管装置。 在一个方面，一个或多个护套设置在球囊周围，治疗剂设置在护套内，设置在护套上，被包含在护套和气囊之间的空间中，或者与护套相关联。 另一方面，气囊包括用于药物递送的微机电系统（MEMS）。
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公开(公告)号：US20090227949A1
公开(公告)日：2009-09-10
申请号：US12399548
申请日：2009-03-06
申请人： David Knapp , Timothy J. Mickley , John Chen , Derek Sutermeister , Toby Freyman , Gordon Kocur , Daniel Horn , Jim Anderson , Ben Arcand , Jay Rassat , Raed Rizq , Irina Nazarova , Dan Quillin , Jan Weber , Torsten Scheuermann
发明人： David Knapp , Timothy J. Mickley , John Chen , Derek Sutermeister , Toby Freyman , Gordon Kocur , Daniel Horn , Jim Anderson , Ben Arcand , Jay Rassat , Raed Rizq , Irina Nazarova , Dan Quillin , Jan Weber , Torsten Scheuermann
IPC分类号： A61M25/10
CPC分类号： A61M25/1029 , A61L29/085 , A61L29/16 , A61L2300/416 , A61M25/0045 , A61M25/10 , A61M2025/0056 , A61M2025/1031 , A61M2025/105 , B29L2009/005 , C08L53/02
摘要： Catheter devices having an expandable balloon for delivering a therapeutic agent to a body site. The balloon has one or more folds which serve as a reservoir for containing the therapeutic agent. The fold may have any of various configurations to hold the therapeutic agent. In some cases, the balloon comprises one or more lobes that forms the fold(s). The therapeutic agent may be provided in various ways. For example, the therapeutic agent may be contained in packets that rupture upon expansion of the balloon, or as a plurality of discrete bulk masses, or sealed within compartments.
摘要翻译： 具有用于将治疗剂递送到身体部位的可膨胀气囊的导管装置。 气囊具有一个或多个折叠，其用作容纳治疗剂的储存器。 折叠可以具有保持治疗剂的各种构造中的任何一种。 在一些情况下，气囊包括形成褶皱的一个或多个凸起。 治疗剂可以以各种方式提供。 例如，治疗剂可以包含在囊膨胀时破裂的包装中，或者作为多个离散的体积块，或者密封在隔室内。
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4.发明申请公开(公告)号：US20060142834A1
公开(公告)日：2006-06-29
申请号：US11022585
申请日：2004-12-23
申请人： Raed Rizq , John Chen , Stanley Nordin
发明人： Raed Rizq , John Chen , Stanley Nordin
IPC分类号： A61F2/06
CPC分类号： A61M25/1027 , A61F2/958 , A61F2002/9583 , A61M2025/1088
摘要： In an assembly of a balloon mounted on a catheter and a stent mounted over the deflated balloon, the balloon is provided with a fugitive plasticizer before the stent is crimped over the balloon. The fugitive plasticizer can soften the balloon surface so that molding of the balloon surface to conform to the crimped stent occurs. The fugitive plasticizer is removed before the assembly is used.
摘要翻译： 在安装在导管和安装在放气气球上的支架上的气囊的组件中，气囊在支架被压接在气囊之前设置有缓冲增塑剂。 短促增塑剂可以软化球囊表面，从而发生球囊表面的模制以符合卷曲的支架。 在使用组装之前，除去挥发性增塑剂。
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公开(公告)号：US20050159805A1
公开(公告)日：2005-07-21
申请号：US10759605
申请日：2004-01-20
申请人： Jan Weber , Tom Holman , Tracee Eidenschink , John Chen
发明人： Jan Weber , Tom Holman , Tracee Eidenschink , John Chen
IPC分类号： A61F2/00 , A61F2/06 , A61F2/90 , A61L27/30 , A61L27/54 , A61L27/56 , A61L31/08 , A61L31/14 , A61L31/16
CPC分类号： A61L31/16 , A61F2/91 , A61F2250/0068 , A61L31/082 , A61L31/146 , A61L2300/606
摘要： The present invention regards an implant that may be uniquely shaped to enhance its functionality and that may also be coated with a coating system that affects its functionality. In one embodiment the implant may have a first surface that is covered with a filter material, the filter material being in contact with a catalyst that promotes the decomposition of Hydrogen Peroxide into Hydrogen and Oxygen. In this and other embodiments, this filter material may be made from ceramic materials and may be meso-porous. In another embodiment, the implant may or may not be coated with this system and may have at least one strut with a tapered cross-section, the cross-section becoming smaller in area when moving from a reference point on the inside of the implant to the outside of the implant.
摘要翻译： 本发明涉及一种植入物，其可以是独特的形状以增强其功能，并且还可以涂覆有影响其功能的涂层系统。 在一个实施例中，植入物可以具有被过滤材料覆盖的第一表面，过滤材料与促进过氧化氢分解成氢气和氧气的催化剂接触。 在该实施例和其它实施例中，该过滤材料可以由陶瓷材料制成，并且可以是中孔多孔的。 在另一个实施例中，植入物可以涂覆或可以不涂覆该系统，并且可以具有至少一个具有锥形横截面的支柱，当从植入物内侧的参考点移动到该植入物的横截面时，横截面变小 外植入物。
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公开(公告)号：US20050074479A1
公开(公告)日：2005-04-07
申请号：US10677834
申请日：2003-10-03
申请人： Jan Weber , Tom Holman , Tracee Eidenschink , John Chen
发明人： Jan Weber , Tom Holman , Tracee Eidenschink , John Chen
CPC分类号： A61K31/01 , A61F2/0077 , A61F2/02 , A61F2/04 , A61F2/06 , A61F2/07 , A61F2/82 , A61F2250/0067 , A61K9/00 , A61K45/06 , A61L27/303 , A61L31/084
摘要： Methods, systems, and uses of bucky paper are provided in the present invention. These embodiments include covering medical implants with single or multiple layers of bucky paper, treating bucky paper with various therapeutics to be released through the bucky paper to a target site, shaping bucky paper into non-conventional configurations for improved therapeutic deliver, and using bucky paper alone or in conjunction with other materials to treat a target site.
摘要翻译： 本发明提供了巴克纸的方法，系统和用途。 这些实施方案包括用单层或多层巴克纸覆盖医疗植入物，用各种治疗剂处理巴克纸以通过巴克纸释放到目标部位，将巴克纸成形为非常规构型以改善治疗递送，并使用巴克纸 单独或与其他材料结合来治疗目标部位。
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公开(公告)号：US20060184112A1
公开(公告)日：2006-08-17
申请号：US11060093
申请日：2005-02-17
申请人： Daniel Horn , John Chen , Jan Weber , Thomas Holman
发明人： Daniel Horn , John Chen , Jan Weber , Thomas Holman
IPC分类号： A61F2/06
CPC分类号： A61M25/104 , A61F2002/9583 , A61F2250/0068 , A61L29/126 , A61M2025/1086
摘要： Medical devices and related methods are disclosed.
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公开(公告)号：US20070250101A1
公开(公告)日：2007-10-25
申请号：US11407576
申请日：2006-04-20
申请人： Daniel Horn , John Chen , Ying Xiong , Joe Khammoungkhoune , John Blix , Aaron Khieu
发明人： Daniel Horn , John Chen , Ying Xiong , Joe Khammoungkhoune , John Blix , Aaron Khieu
IPC分类号： A61M29/00
CPC分类号： A61M25/10 , A61L29/049 , A61L29/14 , A61L29/143 , A61M25/1002 , A61M25/1029 , A61M25/104 , A61M2025/1075 , A61M2025/1084 , A61M2025/1088 , A61M2205/0216 , B32B5/02 , C08L23/06 , C08L75/04 , C08L77/00 , Y10T428/1334 , Y10T428/1352 , Y10T428/1362 , Y10T428/1366 , Y10T428/1372 , Y10T428/1386
摘要： Composite fiber reinforced balloons for medical devices are prepared by applying a web of fibers to the exterior of a preformed underlayer balloon, encasing the web with a matrix material to form an assembly, and inserting the assembly into a preformed outer layer balloon to form the composite balloon.
摘要翻译： 用于医疗装置的复合纤维增强球囊通过将纤维网施加到预成型下层球囊的外部，用基质材料包裹纤维网以形成组件并将组件插入预成型的外层气囊中以形成复合物 气球。
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公开(公告)号：US20060008606A1
公开(公告)日：2006-01-12
申请号：US10889574
申请日：2004-07-07
申请人： Daniel Horn , Jeffrey Lindquist , Irina Nazarova , Scott Schewe , David Meister , John Chen
发明人： Daniel Horn , Jeffrey Lindquist , Irina Nazarova , Scott Schewe , David Meister , John Chen
IPC分类号： B29D22/00
CPC分类号： A61M25/1029 , A61L29/126 , Y10T156/103 , Y10T428/13 , Y10T428/1303 , Y10T428/1352 , Y10T428/1359 , Y10T428/1362 , Y10T428/1369 , Y10T428/139
摘要： Composite fiber reinforced balloons for medical devices prepared by applying a web of fibers to the exterior of a preformed underlying balloon and encasing the web with a matrix material to form a composite balloon. The fiber web is applied to at least the cone portion of the underlying balloon form. Either the cone portion of the underlying balloon form, or the web fibers applied to said cone portion, or both, have a friction-enhancing material coated thereon.
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