-
公开(公告)号：US20160369232A1
公开(公告)日：2016-12-22
申请号：US15189215
申请日：2016-06-22
申请人： Mari Dezawa , Yoshinori Fujiyoshi , Youichi Nabeshima , Shohei Wakao , Masanori Yoshida , Yasumasa Kuroda
发明人： Mari Dezawa , Yoshinori Fujiyoshi , Youichi Nabeshima , Shohei Wakao , Masanori Yoshida , Yasumasa Kuroda
IPC分类号： C12N5/074 , C12N5/073 , C12N5/0775
CPC分类号： C12N5/0607 , A61K35/12 , A61K35/28 , A61K35/50 , A61K35/51 , A61K2035/124 , C12N5/0605 , C12N5/0662 , C12N5/0663 , C12N5/0665 , C12N5/0667 , C12N2500/02 , C12N2500/84 , C12N2500/90 , C12N2501/06 , C12N2501/734 , C12N2501/998 , C12N2502/025
摘要： Objects of the present invention are to provide a method for directly obtaining pluripotent stem cells which do not have tumorigenic property from body tissue and the thus obtained pluripotent stem cells. The present invention relates to SSEA-3 (+) pluripotent stem cells that can be isolated from body tissue.
摘要翻译： 本发明的目的是提供直接获得不具有来自身体组织和由此获得的多能干细胞的致瘤性的多能干细胞的方法。 本发明涉及可从身体组织分离的SSEA-3（+）多能干细胞。
-
公开(公告)号：US20180355313A1
公开(公告)日：2018-12-13
申请号：US16104224
申请日：2018-08-17
申请人： Mari Dezawa , Yoshinori Fujiyoshi , Youichi Nabeshima , Shohei Wakao , Masanori Yoshida , Yasumasa Kuroda
发明人： Mari Dezawa , Yoshinori Fujiyoshi , Youichi Nabeshima , Shohei Wakao , Masanori Yoshida , Yasumasa Kuroda
IPC分类号： C12N5/074 , C12N5/0775 , A61K35/28
CPC分类号： C12N5/0607 , A61K35/12 , A61K35/28 , A61K35/50 , A61K35/51 , A61K2035/124 , C12N5/0605 , C12N5/0662 , C12N5/0663 , C12N5/0665 , C12N5/0667 , C12N2500/02 , C12N2500/84 , C12N2500/90 , C12N2501/06 , C12N2501/734 , C12N2501/998 , C12N2502/025
摘要： Objects of the present invention are to provide a method for directly obtaining pluripotent stern cells which do not have tumorigenic property from body tissue and the thus obtained pluripotent stem cells. The present invention relates to SSEA-3 (+) pluripotent stern cells that can be isolated from body tissue.
-
公开(公告)号：US09550975B2
公开(公告)日：2017-01-24
申请号：US12836264
申请日：2010-07-14
IPC分类号： C12N15/02 , C12N5/00 , C12N5/074 , C12N15/113 , C12N5/0775 , C12N15/86 , C12N5/073 , A61K35/50 , A61K35/12 , A61K35/28
CPC分类号： C12N5/0607 , A61K35/12 , A61K35/28 , A61K35/50 , C12N5/0605 , C12N5/0662 , C12N5/0663 , C12N5/0667 , C12N5/0668 , C12N5/0696 , C12N15/1138 , C12N15/86 , C12N2506/1353 , C12N2509/00
摘要： Objects of the present invention are to provide a method for directly obtaining pluripotent stem cells from body tissue and the thus obtained pluripotent stem cells. The present invention relates to SSEA-3 (+) pluripotent stem cells that can be isolated from body tissue.
摘要翻译： 本发明的目的是提供从身体组织和由此获得的多能干细胞直接获得多能干细胞的方法。 本发明涉及可从身体组织分离的SSEA-3（+）多能干细胞。
-
4.发明授权公开(公告)号：US09399758B2
公开(公告)日：2016-07-26
申请号：US13435703
申请日：2012-03-30
IPC分类号： C12N15/02 , C12N5/00 , C12N5/074 , A61K35/28 , C12N5/0775 , A61K35/51 , C12N5/073 , A61K35/12 , A61K35/50
CPC分类号： C12N5/0607 , A61K35/12 , A61K35/28 , A61K35/50 , A61K35/51 , A61K2035/124 , C12N5/0605 , C12N5/0662 , C12N5/0663 , C12N5/0665 , C12N5/0667 , C12N2500/02 , C12N2500/84 , C12N2500/90 , C12N2501/06 , C12N2501/734 , C12N2501/998 , C12N2502/025
摘要： Objects of the present invention are to provide a method for directly obtaining pluripotent stem cells which do not have tumorigenic property from body tissue and the thus obtained pluripotent stem cells. The present invention relates to SSEA-3 (+) pluripotent stem cells that can be isolated from body tissue.
摘要翻译： 本发明的目的是提供直接获得不具有来自身体组织和由此获得的多能干细胞的致瘤性的多能干细胞的方法。 本发明涉及可从身体组织分离的SSEA-3（+）多能干细胞。
-
公开(公告)号：US11261426B2
公开(公告)日：2022-03-01
申请号：US15189215
申请日：2016-06-22
摘要： Objects of the present invention are to provide a method for directly obtaining pluripotent stem cells which do not have tumorigenic property from body tissue and the thus obtained pluripotent stem cells. The present invention relates to SSEA-3 (+) pluripotent stem cells that can be isolated from body tissue.
-
公开(公告)号：US20120244129A1
公开(公告)日：2012-09-27
申请号：US13435703
申请日：2012-03-30
申请人： Mari Dezawa , Yoshinori Fujiyoshi , Youichi Nabeshima , Shohei Wakao , Masanori Yoshida , Yasumasa Kuroda
发明人： Mari Dezawa , Yoshinori Fujiyoshi , Youichi Nabeshima , Shohei Wakao , Masanori Yoshida , Yasumasa Kuroda
IPC分类号： C12N5/074 , C12N13/00 , A61K35/12 , C12N5/0775
CPC分类号： C12N5/0607 , A61K35/12 , A61K35/28 , A61K35/50 , A61K35/51 , A61K2035/124 , C12N5/0605 , C12N5/0662 , C12N5/0663 , C12N5/0665 , C12N5/0667 , C12N2500/02 , C12N2500/84 , C12N2500/90 , C12N2501/06 , C12N2501/734 , C12N2501/998 , C12N2502/025
摘要： Objects of the present invention are to provide a method for directly obtaining pluripotent stem cells which do not have tumorigenic property from body tissue and the thus obtained pluripotent stem cells. The present invention relates to SSEA-3 (+) pluripotent stem cells that can be isolated from body tissue.
摘要翻译： 本发明的目的是提供直接获得不具有来自身体组织和由此获得的多能干细胞的致瘤性的多能干细胞的方法。 本发明涉及可从身体组织分离的SSEA-3（+）多能干细胞。
-
公开(公告)号：US07667005B2
公开(公告)日：2010-02-23
申请号：US12046718
申请日：2008-03-12
申请人： Youichi Nabeshima , Makoto Kuroo , Susumu Sekine , Akihiro Iida
发明人： Youichi Nabeshima , Makoto Kuroo , Susumu Sekine , Akihiro Iida
IPC分类号： C07K16/28
CPC分类号： C12N15/8509 , A01K67/0275 , A01K67/0276 , A01K67/0278 , A01K2207/15 , A01K2217/00 , A01K2217/05 , A01K2217/075 , A01K2227/105 , A01K2267/03 , A01K2267/0306 , A01K2267/0393 , A61K38/00 , A61K48/00 , C07K14/47 , C07K16/18 , C12N2799/026 , C12N2800/30
摘要： The present invention relates to a polypeptide having an activity of suppressing aging; DNA encoding the polypeptide; a method for improving livestock, using the DNA; a recombinant DNA prepared by inserting the DNA into a vector; a transformant harboring the recombinant; a method for preparing the polypeptide of the present invention, using the transformant; an antibody which recognizes the polypeptide; a ligand for the polypeptide of the present invention; a compound inhibiting specific binding between the polypeptide and ligand of the present invention; a compound enhancing the expression of an aging-suppressing gene encoding the aging-suppressing polypeptide of the present invention; an oligonucleotide comprising a sequence of 10 to 50 nucleotides in the nucleotide sequence of the DNA; and a therapeutic agent for a syndrome resembling premature aging, a therapeutic agent for adult diseases or an aging-suppressing agent, using the same.
摘要翻译： 本发明涉及具有抑制老化活性的多肽; 编码多肽的DNA; 使用DNA改善家畜的方法; 通过将DNA插入载体制备的重组DNA; 携带重组体的转化体; 使用该转化体制备本发明多肽的方法; 识别多肽的抗体; 本发明多肽的配体; 抑制本发明的多肽和配体之间的特异性结合的化合物; 提高编码本发明的老化抑制多肽的老化抑制基因的表达的化合物; 在DNA的核苷酸序列中含有10〜50个核苷酸序列的寡核苷酸; 以及类似于过早衰老的综合症的治疗剂，成人疾病的治疗剂或老化抑制剂。
-
公开(公告)号：US20080227158A1
公开(公告)日：2008-09-18
申请号：US12046718
申请日：2008-03-12
申请人： Youichi Nabeshima , Makoto Kuroo , Susumu Sekine , Akihiro Iida
发明人： Youichi Nabeshima , Makoto Kuroo , Susumu Sekine , Akihiro Iida
CPC分类号： C12N15/8509 , A01K67/0275 , A01K67/0276 , A01K67/0278 , A01K2207/15 , A01K2217/00 , A01K2217/05 , A01K2217/075 , A01K2227/105 , A01K2267/03 , A01K2267/0306 , A01K2267/0393 , A61K38/00 , A61K48/00 , C07K14/47 , C07K16/18 , C12N2799/026 , C12N2800/30
摘要： The present invention relates to a polypeptide having an activity of suppressing aging; DNA encoding the polypeptide; a method for improving livestock, using the DNA; a recombinant DNA prepared by inserting the DNA into a vector; a transformant harboring the recombinant; a method for preparing the polypeptide of the present invention, using the transformant; an antibody which recognizes the polypeptide; a ligand for the polypeptide of the present invention; a compound inhibiting specific binding between the polypeptide and ligand of the present invention; a compound enhancing the expression of an aging-suppressing gene encoding the aging-suppressing polypeptide of the present invention; an oligonucleotide comprising a sequence of 10 to 50 nucleotides in the nucleotide sequence of the DNA; and a therapeutic agent for a syndrome resembling premature aging, a therapeutic agent for adult diseases or an aging-suppressing agent, using the same.
摘要翻译： 本发明涉及具有抑制老化活性的多肽; 编码多肽的DNA; 使用DNA改善家畜的方法; 通过将DNA插入载体制备的重组DNA; 携带重组体的转化体; 使用该转化体制备本发明多肽的方法; 识别多肽的抗体; 本发明多肽的配体; 抑制本发明的多肽和配体之间的特异性结合的化合物; 提高编码本发明的老化抑制多肽的老化抑制基因的表达的化合物; 在DNA的核苷酸序列中含有10〜50个核苷酸序列的寡核苷酸; 以及类似于过早衰老的综合症的治疗剂，成人疾病的治疗剂或老化抑制剂。
-
公开(公告)号：US06579850B1
公开(公告)日：2003-06-17
申请号：US09344510
申请日：1999-06-25
申请人： Youichi Nabeshima , Makoto Kuroo , Susumu Sekine , Akihiro Iida
发明人： Youichi Nabeshima , Makoto Kuroo , Susumu Sekine , Akihiro Iida
IPC分类号： A61K3816
CPC分类号： C12N15/8509 , A01K67/0275 , A01K67/0276 , A01K67/0278 , A01K2207/15 , A01K2217/00 , A01K2217/05 , A01K2217/075 , A01K2227/105 , A01K2267/03 , A01K2267/0306 , A01K2267/0393 , A61K38/00 , A61K48/00 , C07K14/47 , C07K16/18 , C12N2799/026 , C12N2800/30
摘要： The present invention relates to a polypeptide having an activity of suppressing aging; DNA encoding the polypeptide; a method for improving livestock, using the DNA; a recombinant DNA prepared by inserting the DNA into a vector; a transformant harboring the recombinant; a method for preparing the polypeptide of the present invention, using the transformant; an antibody which recognizes the polypeptide; a ligand for the polypeptide of the present invention; a compound inhibiting specific binding between the polypeptide and ligand of the present invention; a compound enhancing the expression of an aging-suppressing gene encoding the aging-suppressing polypeptide of the present invention; an oligonucleotide comprising a sequence of 10 to 50 nucleotides in the nucleotide sequence of the DNA; and a therapeutic agent for a syndrome. resembling premature aging, a therapeutic agent for adult diseases or an aging-suppressing agent, using the same.
摘要翻译： 本发明涉及具有抑制老化活性的多肽; 编码多肽的DNA; 使用DNA改善家畜的方法; 通过将DNA插入载体制备的重组DNA; 携带重组体的转化体; 使用该转化体制备本发明多肽的方法; 识别多肽的抗体; 本发明多肽的配体; 抑制本发明的多肽和配体之间的特异性结合的化合物; 提高编码本发明的老化抑制多肽的老化抑制基因的表达的化合物; 在DNA的核苷酸序列中含有10〜50个核苷酸序列的寡核苷酸; 以及类似于过早衰老的综合症的治疗剂，成人疾病的治疗剂或老化抑制剂。
-
-
-
-
-
-
-
-
搜索结果
9 条记录 (耗时 0.025 秒)
