-
公开(公告)号：US20080105831A1
公开(公告)日：2008-05-08
申请号：US11749411
申请日：2007-05-16
IPC分类号： G01J1/58
CPC分类号： G01N21/6428 , G01N21/6452 , G01N21/648 , G01N2021/6432
摘要： An embodiment generally relates to a system for analysis of an analyte. The system can include a transparent substrate. The system also includes an excitation light source configured to induce an evanescent wave excitation of a fluorescently labeled molecule near the access to the transparent substrate and a detector for detecting the fluorescently labeled molecule.
摘要翻译： 实施方案一般涉及用于分析分析物的系统。 该系统可以包括透明基板。 该系统还包括激发光源，其被配置为在靠近透明衬底的位置处诱导荧光标记分子的ev逝波激发和用于检测荧光标记分子的检测器。
-
公开(公告)号：US20100178691A1
公开(公告)日：2010-07-15
申请号：US12730121
申请日：2010-03-23
CPC分类号： G01N21/6428 , G01N21/6452 , G01N21/648 , G01N2021/6432
摘要： An embodiment generally relates to a system for analysis of an analyte. The system can include a transparent substrate. The system also includes an excitation light source configured to induce an evanescent wave excitation of a fluorescently labeled molecule near the access to the transparent substrate and a detector for detecting the fluorescently labeled molecule.
摘要翻译： 实施方案一般涉及用于分析分析物的系统。 该系统可以包括透明基板。 该系统还包括激发光源，其被配置为在靠近透明衬底的位置处诱导荧光标记分子的ev逝波激发和用于检测荧光标记分子的检测器。
-
公开(公告)号：US07709808B2
公开(公告)日：2010-05-04
申请号：US11749411
申请日：2007-05-16
IPC分类号： G01N21/64
CPC分类号： G01N21/6428 , G01N21/6452 , G01N21/648 , G01N2021/6432
摘要： An embodiment generally relates to a system for analysis of an analyte. The system can include a transparent substrate. The system also includes an excitation light source configured to induce an evanescent wave excitation of a fluorescently labeled molecule near the access to the transparent substrate and a detector for detecting the fluorescently labeled molecule.
摘要翻译： 实施方案一般涉及用于分析分析物的系统。 该系统可以包括透明基板。 该系统还包括激发光源，其被配置为在靠近透明衬底的位置处诱导荧光标记分子的ev逝波激发和用于检测荧光标记分子的检测器。
-
公开(公告)号：US07407798B2
公开(公告)日：2008-08-05
申请号：US11096341
申请日：2005-03-31
申请人： Mark F. Oldham , Richard T. Reel , Steven J. Boege
发明人： Mark F. Oldham , Richard T. Reel , Steven J. Boege
CPC分类号： G01N21/6452 , B01L7/52 , B01L2300/046 , B01L2300/0654 , B01L2300/0829 , G01N21/253 , G02B3/0056 , G02B3/08
摘要： The invention relates to an optical detection system for a thermal cycling device including at least one light source, a light detection device for detecting light received from a plurality of biological samples, and a lens having a plurality of focusing lens segments greater than the plurality of biological samples to direct light into the plurality of biological samples.
摘要翻译： 本发明涉及一种用于热循环装置的光学检测系统，其包括至少一个光源，用于检测从多个生物样本接收的光的光检测装置，以及具有大于多个生物样本的多个聚焦透镜段的透镜 生物样品将光引导到多个生物样品中。
-
公开(公告)号：US20100103416A1
公开(公告)日：2010-04-29
申请号：US12630683
申请日：2009-12-03
IPC分类号： G01N21/00
CPC分类号： G01N27/44721 , B82Y10/00 , B82Y20/00 , G01N2015/149 , G01N2015/1497
摘要： An apparatus for detecting labeled beads is provided. The apparatus can include: one or more irradiation sources disposed for irradiating the one or more detection zones with radiation; at least one detector disposed for collecting charges corresponding to light signals emitted from labeled beads in the one or more detection zones, which have been excited by the radiation; and a system coupled to the at least one detector for effecting time delay integration of the charges by accumulating the charges before reading the charges at the output of the at least one detector.
摘要翻译： 提供了一种用于检测标记珠粒的装置。 该装置可以包括：一个或多个辐射源，被设置用于用辐射照射一个或多个检测区域; 至少一个检测器被设置用于收集对应于已经被辐射激发的一个或多个检测区域中的标记珠子发射的光信号的电荷; 以及耦合到所述至少一个检测器的系统，用于通过在读取至少一个检测器的输出端的电荷之前累积电荷来实现电荷的时间延迟积分。
-
公开(公告)号：US07636160B2
公开(公告)日：2009-12-22
申请号：US12321781
申请日：2009-01-26
申请人： Mark F. Oldham , Eric S. Nordman , Richard T. Reel , John S. Shigeura , Janice G. Shigeura, legal representative
IPC分类号： G01N21/00
CPC分类号： G01N27/44721 , B82Y10/00 , B82Y20/00 , G01N2015/149 , G01N2015/1497
摘要： An apparatus for detecting labeled beads is provided. The apparatus can include: one or more irradiation sources disposed for irradiating the one or more detection zones with radiation; at least one detector disposed for collecting charges corresponding to light signals emitted from labeled beads in the one or more detection zones, which have been excited by the radiation; and a system coupled to the at least one detector for effecting time delay integration of the charges by accumulating the charges before reading the charges at the output of the at least one detector.
摘要翻译： 提供了一种用于检测标记珠粒的装置。 该装置可以包括：一个或多个辐射源，被设置用于用辐射照射一个或多个检测区域; 至少一个检测器被设置用于收集对应于已经被辐射激发的一个或多个检测区域中的标记珠子发射的光信号的电荷; 以及耦合到所述至少一个检测器的系统，用于通过在读取至少一个检测器的输出端的电荷之前累积电荷来实现电荷的时间延迟积分。
-
公开(公告)号：US07636159B2
公开(公告)日：2009-12-22
申请号：US12283957
申请日：2008-09-17
申请人： Mark F. Oldham , Eric S. Nordman , Richard T. Reel , John S. Shigeura , Janice G. Shigeura, legal representative
IPC分类号： G01N21/00
CPC分类号： G01N27/44721 , B82Y10/00 , B82Y20/00 , G01N2015/149 , G01N2015/1497
摘要： An apparatus for detecting labeled beads is provided. The apparatus can include: one or more irradiation sources disposed for irradiating the one or more detection zones with radiation; at least one detector disposed for collecting charges corresponding to light signals emitted from labeled beads in the one or more detection zones, which have been excited by the radiation; and a system coupled to the at least one detector for effecting time delay integration of the charges by accumulating the charges before reading the charges at the output of the at least one detector.
-
公开(公告)号：US20090021735A1
公开(公告)日：2009-01-22
申请号：US12283957
申请日：2008-09-17
IPC分类号： G01N21/62
CPC分类号： G01N27/44721 , B82Y10/00 , B82Y20/00 , G01N2015/149 , G01N2015/1497
摘要： An apparatus for detecting labeled beads is provided. The apparatus can include: one or more irradiation sources disposed for irradiating the one or more detection zones with radiation; at least one detector disposed for collecting charges corresponding to light signals emitted from labeled beads in the one or more detection zones, which have been excited by the radiation; and a system coupled to the at least one detector for effecting time delay integration of the charges by accumulating the charges before reading the charges at the output of the at least one detector.
摘要翻译： 提供了一种用于检测标记珠粒的装置。 该装置可以包括：一个或多个辐射源，被设置用于用辐射照射一个或多个检测区域; 至少一个检测器被设置用于收集对应于已经被辐射激发的一个或多个检测区域中的标记珠子发射的光信号的电荷; 以及耦合到所述至少一个检测器的系统，用于通过在读取至少一个检测器的输出端的电荷之前累积电荷来实现电荷的时间延迟积分。
-
9.发明授权Device, system, and method for depositing processed immiscible-fluid-discrete-volumes 有权用于存放经处理的不混溶流体离散体的装置，系统和方法公开(公告)号：US09285297B2
公开(公告)日：2016-03-15
申请号：US11507733
申请日：2006-08-22
IPC分类号： C12Q1/68 , C12P19/34 , G01N1/14 , B01L3/00 , F15C5/00 , F16K99/00 , G01N35/08 , B01L3/02 , B01L7/00
CPC分类号： C12Q1/6869 , B01J2219/00353 , B01J2219/0036 , B01J2219/00364 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00619 , B01J2219/00626 , B01J2219/00637 , B01J2219/00653 , B01J2219/00657 , B01J2219/00659 , B01L3/0293 , B01L3/502715 , B01L3/502784 , B01L7/52 , B01L2200/0673 , B01L2200/10 , B01L2300/0864 , B01L2300/0867 , B01L2400/0421 , B01L2400/0487 , C12Q1/6806 , C12Q1/6874 , F15C5/00 , F16K99/0001 , F16K99/0011 , F16K99/0013 , F16K2099/0084 , G01N1/14 , G01N27/44743 , G01N27/44769 , G01N35/08 , Y10T137/0318 , Y10T137/4259 , Y10T137/85978 , Y10T137/85986 , Y10T137/86863 , Y10T436/2575 , C12Q2535/101
摘要： Various embodiments relate to systems and/or methods for sample preparation that can be used for biochemical and/or molecular biology procedures involving small volumes, for example, micro volumes or smaller. Methods and systems that can reduce sample size requirements and increase the number of samples on a substrate are provided. Samples can be applied to a plate or other appropriate substrate and can be used for, inter alia, sequencing reactions. In some embodiments, apparatuses, systems, and/or methods for charged analyte collection are provided. Charged analytes in a sample can be electrokinetically collected or extracted from a conduit through a hole formed in a sidewall of the conduit, by application of an electric field that causes the charged analytes to migrate in a direction that is transverse to the conduit.
摘要翻译： 各种实施方案涉及用于样品制备的系统和/或方法，其可用于涉及小体积例如微量或更小的生物化学和/或分子生物学过程。 提供了可以减少样品尺寸要求并增加基材上样品数量的方法和系统。 样品可以施用于板或其它合适的底物，并且可以用于尤其是测序反应。 在一些实施例中，提供了用于带电分析物收集的装置，系统和/或方法。 通过施加导致带电分析物沿横向于导管的方向迁移的电场，样品中的带电分析物可以通过形成在导管侧壁中的孔从导管电动收集或提取。
-
公开(公告)号：US07978326B2
公开(公告)日：2011-07-12
申请号：US12630683
申请日：2009-12-03
申请人： Mark F. Oldham , Eric S. Nordman , Richard T. Reel , John S. Shigeura , Janice G. Shigeura, legal representative
IPC分类号： G01N21/00
CPC分类号： G01N27/44721 , B82Y10/00 , B82Y20/00 , G01N2015/149 , G01N2015/1497
摘要： An apparatus for detecting labeled beads is provided. The apparatus can include: one or more irradiation sources disposed for irradiating the one or more detection zones with radiation; at least one detector disposed for collecting charges corresponding to light signals emitted from labeled beads in the one or more detection zones, which have been excited by the radiation; and a system coupled to the at least one detector for effecting time delay integration of the charges by accumulating the charges before reading the charges at the output of the at least one detector.
摘要翻译： 提供了一种用于检测标记珠粒的装置。 该装置可以包括：一个或多个辐射源，被设置用于用辐射照射一个或多个检测区域; 至少一个检测器被设置用于收集对应于已经被辐射激发的一个或多个检测区域中的标记珠子发射的光信号的电荷; 以及耦合到所述至少一个检测器的系统，用于通过在读取至少一个检测器的输出端的电荷之前累积电荷来实现电荷的时间延迟积分。
-
-
-
-
-
-
-
-
-
搜索结果
40 条记录 (耗时 0.029 秒)
