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公开(公告)号：US20170044481A1
公开(公告)日：2017-02-16
申请号：US15336378
申请日：2016-10-27
Applicant: OLYMPUS CORPORATION
Inventor： Yoshihiro KAWANO , Hiroyuki KIMURA
CPC classification number: C12M31/00 , C12M23/08 , C12M23/22 , C12M31/04 , C12M31/06 , C12M41/36 , G06K9/52 , H04N1/00 , H04N5/2254 , H04N5/2256 , H04N5/232 , H04N5/23212 , H04N5/44
Abstract: Provided is a culturing observation apparatus including: a light source portion that radiates illumination light into a culturing container, in which cells are being cultured, from a side surface of the culturing container, which is optically transparent, within a predetermined angular range; an image-acquisition portion that, when the illumination light radiated from the light source portion is scattered at the cells in the culturing container and when a portion of this scattered light passes through a bottom surface of the culturing container, acquires an image by capturing the scattered light that has passed through the bottom surface; and a transmitting portion that transmits the image acquired by the image-acquisition portion to an exterior.
Abstract translation: 本发明提供一种培养观察装置，其特征在于，包括：光源部，其从规定的角度范围内的光学透明的培养容器的侧面向被培养细胞的培养容器中照射照明光; 当从光源部分照射的照明光在培养容器中的细胞散射时，当该散射光的一部分通过培养容器的底面时，拍摄图像， 已经穿过底面的散射光; 以及发送部，其将由图像获取部获取的图像发送到外部。
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公开(公告)号：US20160108353A1
公开(公告)日：2016-04-21
申请号：US14882954
申请日：2015-10-14
Applicant: OLYMPUS CORPORATION
Inventor： Hiroyuki KIMURA
CPC classification number: C12M41/36 , C12M31/10 , C12M41/06 , C12M41/08 , C12M41/14 , G01N15/1434 , G01N15/1475 , G01N21/47 , G01N2015/1006 , G01N2015/1479 , G01N2201/062 , H04N5/2256 , H04N7/183
Abstract: An object is to lessen a troublesome checking task during cell culturing. A culture observation apparatus of the present invention includes: a light source unit that radiates illumination light onto the inside of a transparent culture vessel from a side surface of the culture vessel; an image acquisition unit that images, of the illumination light radiated from the light source unit, scattered light emitted from the inside of the culture vessel to acquire images; and a transmission unit that sends the images acquired by the image acquisition unit to the outside. The image acquisition unit includes a sensor array that has a plurality of sensors arranged in at least one line over approximately the entire length in one direction of a bottom surface of the culture vessel and a movement mechanism that relatively moves the sensor array and the culture vessel in a direction intersecting the array direction of the sensors and extending along the bottom surface.
Abstract translation: 目的是减轻细胞培养过程中麻烦的检查任务。 本发明的培养观察装置包括：光源单元，其从培养容器的侧面将照明光照射到透明培养容器的内部; 图像获取单元，对从所述光源单元辐射的照明光进行成像，从所述培养容器内部发射的散射光获取图像; 以及发送单元，其将由图像获取单元获取的图像发送到外部。 所述图像获取单元包括传感器阵列，所述传感器阵列具有多个传感器，所述传感器布置在所述培养容器的底表面的大致整个长度上的至少一条线上;以及移动机构，所述移动机构使所述传感器阵列和所述培养容器 在与传感器的阵列方向相交的方向上沿着底面延伸。
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公开(公告)号：US20190216304A1
公开(公告)日：2019-07-18
申请号：US16358938
申请日：2019-03-20
Applicant: OLYMPUS CORPORATION
Inventor： Hiroyuki KIMURA
CPC classification number: A61B1/051 , A61B1/00114 , A61B1/00124 , A61B1/04 , G02B23/24 , H01B7/0009 , H01B7/20 , H04N5/2251 , H04N2005/2255 , H05K1/147 , H05K1/189 , H05K2201/10121 , H05K2201/10151 , H05K2201/10356 , H05K2201/10734
Abstract: An electronic circuit unit includes: a cable having a core of stranded thin wires, the core being covered with an outer surface, the outer surface at one end of the cable being removed to expose the core; a metallic tube that is tubular, the exposed core being inserted into an opening portion of the metallic tube; and a substrate including a connection land for connecting the core. The exposed core is connected to the connection land via the metallic tube by diffusion joining or ultrasound joining, the core has a diameter of 0.02 to 0.50 mm, the metallic tube has a thickness of 10 to 50 μm, and the metallic tube has an inner diameter that is larger than the diameter of the core by equal to or more than 1.1-fold and equal to or less than by 1.5-fold.
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公开(公告)号：US20170327782A1
公开(公告)日：2017-11-16
申请号：US15666551
申请日：2017-08-01
Applicant: OLYMPUS CORPORATION
Inventor： Hiroyuki KIMURA , Tatsuya MINAMI , Yasunori MAKARA
CPC classification number: C12M37/04 , C12M23/34 , C12M23/52 , C12M29/00 , C12M33/00 , C12M41/00 , C12M41/14
Abstract: Provided is a cell-culturing apparatus including a culturing unit in which a culturing vessel is placed and an incubator in which a plurality of culturing units are placed in an interior thereof, and that can maintain the interior thereof at an environment that is appropriate for cell culturing, wherein the incubator includes openings that are provided for each of the plurality of culturing units and through which the culturing units can separately be moved into and out of the incubator, and closing means that are provided at the openings and that seals off the internal environment of the incubator from outside when the culturing unit is taken out of the incubator.
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公开(公告)号：US20170158996A1
公开(公告)日：2017-06-08
申请号：US15431153
申请日：2017-02-13
Applicant: OLYMPUS CORPORATION
Inventor： Hiroyuki KIMURA , Tatsuya MINAMI , Yasunori MAKARA
Abstract: A cell culture apparatus according to the present invention includes a cell culture bag and a culture tank. The cell culture bag is composed of a bag-shaped film material capable of accommodating cells and a culture medium therein. At least a part of the bag-shaped film material is formed of a porous membrane that selectively allows a substance contained in the culture medium to pass through but does not allow the cells to pass through. The culture tank retains the cell culture bag in an immersed state in a solution.
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Patent Agency Ranking
公开(公告)号：US20170107475A1
公开(公告)日：2017-04-20
申请号：US15391804
申请日：2016-12-27
Applicant: OLYMPUS CORPORATION
Inventor： Hiroyuki KIMURA , Tatsuya MINAMI , Yasunori MAKARA
Abstract: A cell-culturing system includes: a solution-holding means holding a medium; and a solution-supplying means supplying the solution supplied thereto from the solution-holding means to a cell-culturing container. The solution-supplying means may supply a solution to the container via a solution dripping step. The container may be connected to the solution-supplying means at a position that is lower than the solution-supplying means in a direction in which gravity acts; the solution-supplying means may have a space in which the solution supplied thereto from the solution-holding means is made to drip; the system may be provided with a discharging port discharging the solution at a position in a container side surface at a desired height; and the solution may be discharged outside when the height of a top surface of the solution in the container reaches the port as a result of supplying the solution to the container from the solution-supplying means.
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公开(公告)号：US20170022469A1
公开(公告)日：2017-01-26
申请号：US15208663
申请日：2016-07-13
Applicant: OLYMPUS CORPORATION
Inventor： Hiroyuki KIMURA , Tatsuya MINAMI , Yasunori MAKARA
CPC classification number: C12M41/48 , C12M23/14 , C12M23/58 , C12M29/00 , C12M29/10 , C12M29/14 , C12M33/04 , C12M41/00 , C12M41/12 , C12M41/14 , C12M41/40 , C12M41/44
Abstract: A cell culturing apparatus according to the present invention includes a culture-medium retaining unit that retains a culture medium for culturing a cell, a culture bag provided with a feed port and a discharge port, a culture-medium feeding unit that connects the culture-medium retaining unit and the feed port and that feeds the culture medium from the culture-medium retaining unit to the culture bag, a negative-pressure supplying unit that supplies negative pressure to the discharge port, and a waste retaining unit that retains the culture medium from the discharge port.
Abstract translation: 本发明的细胞培养装置包括保留用于培养细胞的培养基的培养基保持单元，设置有进料口和排出口的培养袋，培养基培养装置， 介质保持单元和进料口，并且将培养基从培养基保持单元供给到培养袋，将负压供给到排出口的负压供给单元和保持培养基的废弃物保持单元 从排放口。
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8.发明申请公开(公告)号：US20150259640A1
公开(公告)日：2015-09-17
申请号：US14644055
申请日：2015-03-10
Applicant: OLYMPUS CORPORATION
Inventor： Hiroyuki KIMURA
Abstract: In order to determine the culturing state of cells in a culture vessel in a simple manner at an appropriate timing without removing the culture vessel from the culturing apparatus, a cell culturing apparatus includes a culturing chamber that accommodates a culture vessel, which can accommodate cells in the interior thereof, and that maintains a predetermined temperature and humidity; a touchscreen sensor that is disposed inside the culturing chamber on a mounting surface, on which the culture vessel is placed, and that is brought into tight contact with an external surface of a bottom of the culture vessel; and an output portion that exports an output from the touchscreen sensor to the exterior of the culturing chamber.
Abstract translation: 为了在适当的时间以简单的方式确定培养容器中的细胞的培养状态，而不从培养装置中移出培养容器，细胞培养装置包括：培养室，其容纳可容纳细胞的培养容器 其内部并保持预定的温度和湿度; 触摸屏传感器，其设置在所述培养室内，所述培养室内放置有所述培养容器，并且与所述培养容器的底部的外表面紧密接触; 以及将触摸屏传感器的输出输出到培养室外部的输出部。
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公开(公告)号：US20180320120A1
公开(公告)日：2018-11-08
申请号：US16031312
申请日：2018-07-10
Applicant: OLYMPUS CORPORATION
Inventor： Hiroyuki KIMURA , Tatsuya MINAMI , Yasunori MAKARA
CPC classification number: C12M1/36 , B01L1/00 , B01L2300/02 , B01L2300/0861 , B01L2400/0457 , C12M3/00 , C12M23/02 , C12M23/42 , C12M29/00 , C12M41/32 , C12M41/44
Abstract: A cell culture container includes, in sequence from above in the gravity direction: a culture-medium holding container; a cell holding container that holds cells and a culture medium supplied from the culture-medium holding container through a supply port provided in the top surface thereof; a waste-liquid holding container that holds the culture medium discharged from the cell holding container; and a discharge mechanism for discharging the culture medium that has exceeded a predetermined level from the cell holding container to the waste-liquid holding container.
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公开(公告)号：US20170137771A1
公开(公告)日：2017-05-18
申请号：US15341449
申请日：2016-11-02
Applicant: OLYMPUS CORPORATION
Inventor： Hiroyuki KIMURA , Tatsuya MINAMI , Yasunori MAKARA
IPC: C12M1/00
CPC classification number: C12M41/14
Abstract: A cell culture apparatus of the present invention includes: a body including a space for accommodating a culture container, and an opening through which the culture container is taken in and out; a door that opens and closes the opening; an optical detection unit that includes optical sensors that optically detects an instruction to open and close the opening from a user, and converts the detection by the optical sensors to a signal and sends the signal; and a door open/close unit that receives the signal from the optical detection unit and controls open/close of the opening by the door.
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