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    IMMUNOASSAY AND IMMUNOASSAY APPARATUS
    1.
    发明申请
    IMMUNOASSAY AND IMMUNOASSAY APPARATUS 审中-公开
    免疫和免疫设备

    公开(公告)号：US20140178908A1

    公开(公告)日：2014-06-26

    申请号：US14109442

    申请日：2013-12-17

    Applicant: SYSMEX CORPORATION

    Inventor： Keiko YOSHIKAWA ,  Naoto KOSHIMURA

    IPC: G01N33/543

    CPC classification number: G01N33/543 ,  G01N33/53

    Abstract: A method of competitive immunoassay is provided. The method comprising: creating a first calibration curve created for a first reaction time period and a second calibration curve created for a second reaction time period longer than the first reaction time period; preparing a measurement sample containing a target substance in a specimen, a reactant, and a competitive substance; obtaining a reference information related to the concentration of the target substance after the first reaction time period since the preparation of the measurement sample; first outputting the concentration obtained based on the first calibration curve as a measurement result in the case where the reference information shows that the concentration of the target substance is less than a predetermined threshold; and second outputting the concentration obtained based on the second calibration curve as the measurement result in the case where the reference information obtained in the obtaining is information showing that the concentration of the target substance is more than or equal to the threshold.

    Abstract translation: 提供了一种竞争性免疫测定方法。 该方法包括：产生对于第一反应时间段产生的第一校准曲线和在比第一反应时间段长的第二反应时间段产生的第二校准曲线; 制备在样品，反应物和竞争性物质中含有目标物质的测量样品; 从制备测量样品后的第一反应时间之后获得与目标物质的浓度相关的参考信息; 在参考信息表示目标物质的浓度小于预定阈值的情况下，首先输出基于第一校准曲线获得的浓度作为测量结果; 并且在获取中获得的参考信息是表示目标物质的浓度大于或等于阈值的信息的情况下，第二输出基于第二校准曲线获得的浓度作为测量结果。

    BLOOD CELL ANALYZER AND BLOOD CELL ANALYZING METHOD
    3.
    发明申请
    BLOOD CELL ANALYZER AND BLOOD CELL ANALYZING METHOD 审中-公开
    血细胞分析仪和血细胞分析方法

    公开(公告)号：US20140295488A1

    公开(公告)日：2014-10-02

    申请号：US14227795

    申请日：2014-03-27

    Applicant: SYSMEX CORPORATION

    Inventor： Yusuke KONISHI ,  Yasuyuki KAWASHIMA ,  Kazuhiro YAMADA ,  Keiko YOSHIKAWA

    IPC: G01N21/49

    CPC classification number: G01N21/49 ,  G01N15/0205 ,  G01N15/1434 ,  G01N33/56972 ,  G01N2015/1402

    Abstract: A blood cell analyzer comprising a flow cell configured to flow a measurement specimen containing blood cells, a first light source configured to emit light having a first wavelength, a second light source configured to emit light having a second wavelength different from the first wavelength, a first light receiving portion configured to receive first scattered light generated by irradiating the blood cells in the measurement specimen with light from the first light source, a second light receiving portion configured to receive second scattered light generated by irradiating the blood cells in the measurement specimen with light from the second light source, and a control section configured to classify at least white blood cells from the blood cells contained in the measurement specimen, based on a detection signal output from the first light receiving portion and a detection signal output from the second light receiving portion.

    Abstract translation: 1.一种血细胞分析装置，其特征在于，包括流动池，其构造成使含有血细胞的测定试样流动，配置成发射具有第一波长的光的第一光源，被配置为发射具有与所述第一波长不同的第二波长的光的第二光源， 第一受光部，被配置为接收通过用来自第一光源的光照射测量样本中的血细胞而产生的第一散射光;第二光接收部，被配置为接收通过用测量样本中的血细胞照射而产生的第二散射光， 来自第二光源的光，以及控制部，被配置为基于从第一光接收部输出的检测信号和从第二光输出的检测信号，对包含在测量样本中的血细胞中的至少白细胞进行分类 接收部分。

    METHOD OF MEASURING LIPOPROTEIN'S CAPACITY TO ACCEPT CHOLESTEROL
    5.
    发明申请
    METHOD OF MEASURING LIPOPROTEIN'S CAPACITY TO ACCEPT CHOLESTEROL 审中-公开
    测量脂蛋白的能力以接受胆固醇的方法

    公开(公告)号：US20160109469A1

    公开(公告)日：2016-04-21

    申请号：US14882812

    申请日：2015-10-14

    Applicant: SYSMEX CORPORATION

    Inventor： Amane HARADA ,  Katsuhiro MURAKAMI ,  Maria KIRIYAMA ,  Keiko YOSHIKAWA ,  Keiko MIWA

    IPC: G01N33/92

    CPC classification number: G01N33/92 ,  G01N2333/775 ,  G01N2405/00 ,  G01N2800/044

    Abstract: Provided is a method of measuring a lipoprotein's capacity to accept cholesterol including the steps of: bringing a lipoprotein in a sample into contact with labeled cholesterol to incorporate the labeled cholesterol into the lipoprotein; bringing the lipoprotein having the labeled cholesterol into contact with an antibody that binds to a lipoprotein to form a complex of the lipoprotein and the antibody; and measuring the label incorporated into the complex.

    Abstract translation: 提供了测量脂蛋白接受胆固醇的能力的方法，包括以下步骤：将样品中的脂蛋白与标记的胆固醇接触以将标记的胆固醇并入脂蛋白; 使具有标记胆固醇的脂蛋白与结合脂蛋白的抗体接触以形成脂蛋白和抗体的复合物; 并测量结合到复合物中的标签。

    BIOPARTICLE MEASURING METHOD
    6.
    发明申请
    BIOPARTICLE MEASURING METHOD 审中-公开

    公开(公告)号：US20200033333A1

    公开(公告)日：2020-01-30

    申请号：US16522063

    申请日：2019-07-25

    Applicant: SYSMEX CORPORATION

    Inventor： Kazuya MATSUMOTO ,  Takuya IINO ,  Keiko YOSHIKAWA

    IPC: G01N33/543

    Abstract: Disclosed is a bioparticle measuring method including forming on a solid phase a complex of a sample containing a bioparticle sampled from a specimen, a capturer containing a tag which binds to the solid phase and capable of binding to the bioparticle, and a detector capable of binding to the bioparticle and containing an labeled substance; dissociating a part or a whole of the complex from the solid phase to prepare a measurement sample containing a part or a whole of the complex not fixed on the solid phase; and detecting signals from the measurement sample by a particle analyzer.

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