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公开(公告)号：US20120283272A1
公开(公告)日：2012-11-08
申请号：US13552755
申请日：2012-07-19
申请人： Shoujun Chen , Junyi Zhang , Jun Jiang , Gary Bohnert , Nha Vo , Qinglin Che , Zhiqiang Xia , Lijun Sun
发明人： Shoujun Chen , Junyi Zhang , Jun Jiang , Gary Bohnert , Nha Vo , Qinglin Che , Zhiqiang Xia , Lijun Sun
IPC分类号： A61K31/444 , C07D417/04 , A61K31/497 , A61K31/4436 , C07D409/06 , C07D409/14 , C07D417/14 , A61K31/4439
CPC分类号： C07D417/14 , C07D409/04 , C07D409/06 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04
摘要： The invention relates to certain compounds, or pharmaceutically acceptable salts, solvates, clathrates, or prodrugs thereof, that are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.
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公开(公告)号：US20130165451A9
公开(公告)日：2013-06-27
申请号：US13552755
申请日：2012-07-19
申请人： Shoujun Chen , Junyi Zhang , Jun Jiang , Gary Bohnert , Nha Vo , Qinglin Che , Zhiqiang Xia , Lijun Sun
发明人： Shoujun Chen , Junyi Zhang , Jun Jiang , Gary Bohnert , Nha Vo , Qinglin Che , Zhiqiang Xia , Lijun Sun
IPC分类号： A61K31/444 , C07D417/04 , A61K31/497 , A61K31/4436 , C07D409/06 , C07D409/14 , C07D417/14 , A61K31/4439
CPC分类号： C07D417/14 , C07D409/04 , C07D409/06 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04
摘要： The invention relates to certain compounds, or pharmaceutically acceptable salts, solvates, clathrates, or prodrugs thereof, that are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.
摘要翻译： 本发明涉及可用作免疫抑制剂并用于治疗和预防炎性病症，过敏性疾病和免疫疾病的某些化合物或其药学上可接受的盐，溶剂化物，包合物或前药。
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3.发明授权Compounds inclunding substituted pyridines for inflammation and immune-related uses 失效包含取代吡啶类化合物用于炎症和免疫相关用途的化合物公开(公告)号：US08314130B2
公开(公告)日：2012-11-20
申请号：US12572103
申请日：2009-10-01
申请人： Shoujun Chen , Junyi Zhang , Jun Jiang , Gary Bohnert , Nha Vo , Qinglin Che , Zhiqiang Xia , Lijun Sun
发明人： Shoujun Chen , Junyi Zhang , Jun Jiang , Gary Bohnert , Nha Vo , Qinglin Che , Zhiqiang Xia , Lijun Sun
IPC分类号： A61K31/44
CPC分类号： C07D417/14 , C07D409/04 , C07D409/06 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04
摘要： The invention relates to certain compounds including substituted pyridines, or pharmaceutically acceptable salts, solvates, clathrates, or prodrugs thereof, that are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.
摘要翻译： 本发明涉及可用作免疫抑制剂并用于治疗和预防炎性病症，过敏性疾病和免疫疾病的某些化合物，包括取代的吡啶或其药学上可接受的盐，溶剂合物，包合物或前药。
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公开(公告)号：US20100130510A1
公开(公告)日：2010-05-27
申请号：US12572103
申请日：2009-10-01
申请人： SHOUJUN CHEN , Junyi Zhang , Jun Jiang , Gary Bohnert , Nha Vo , Qinglin Che , Zhiqiang Xia , Lijun Sun
发明人： SHOUJUN CHEN , Junyi Zhang , Jun Jiang , Gary Bohnert , Nha Vo , Qinglin Che , Zhiqiang Xia , Lijun Sun
IPC分类号： A61K31/497 , A61K31/444 , A61K31/4439 , C07D409/14 , C07D401/14 , C07D417/04 , A61P25/28 , A61P19/02 , A61P3/10 , A61P17/00 , A61P37/00 , A61P11/06 , A61P19/08 , A61P25/16
CPC分类号： C07D417/14 , C07D409/04 , C07D409/06 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04
摘要： The invention relates to certain compounds, or pharmaceutically acceptable salts, solvates, clathrates, or prodrugs thereof, that are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.
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5.发明申请公开(公告)号：US20070275960A1
公开(公告)日：2007-11-29
申请号：US11698982
申请日：2007-01-25
申请人： Jun Jiang , Junyi Zhang , Nha Vo , Shoujun Chen
发明人： Jun Jiang , Junyi Zhang , Nha Vo , Shoujun Chen
IPC分类号： A61K31/535 , A61K31/34 , A61K31/38 , A61K31/41 , A61K31/54 , C07D239/00 , C07D277/20 , C07D333/00 , C07D413/00 , C12N5/08 , C07D417/00 , C07D409/00 , C07D307/02 , C07D271/10 , A61P37/00 , A61K31/42 , A61K31/425 , A61K31/505
CPC分类号： C07D333/38 , C07D277/28 , C07D277/56 , C07D307/68 , C07D409/04 , C07D409/12 , C07D409/14 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/12 , C07D417/14
摘要： The invention relates to compounds of structural formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof, wherein R1, X1, X2, Y, Z, L, and n are defined herein. The compounds are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.
摘要翻译： 本发明涉及结构式（I）的化合物或其药学上可接受的盐，溶剂化物，包合物或前药，其中R 1，X 1，X， > 2 ，Y，Z，L和n在本文中定义。 这些化合物可用作免疫抑制剂并用于治疗和预防炎性病症，过敏性疾病和免疫疾病。
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公开(公告)号：US09604978B2
公开(公告)日：2017-03-28
申请号：US14115506
申请日：2012-05-03
申请人： Shoujun Chen , Gary Bohnert , Jun Jiang , Zhiqiang Xia
发明人： Shoujun Chen , Gary Bohnert , Jun Jiang , Zhiqiang Xia
IPC分类号： A61K31/4965 , C07D401/12 , C07D417/14 , A61K31/165 , A61K31/44 , A61K31/497 , C07D401/14 , C07D405/14 , C07D413/14 , C07D213/82
CPC分类号： C07D417/14 , A61K31/165 , A61K31/44 , A61K31/497 , C07D213/82 , C07D401/12 , C07D401/14 , C07D405/14 , C07D413/14
摘要： The invention relates to certain compounds or pharmaceutically acceptable salts, solvates, clathrates, or prodrugs thereof, that are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.
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公开(公告)号：US20140171446A1
公开(公告)日：2014-06-19
申请号：US14115506
申请日：2012-05-03
申请人： Shoujun Chen , Gary Bohnert , Jun Jiang , Zhiqiang Xia
发明人： Shoujun Chen , Gary Bohnert , Jun Jiang , Zhiqiang Xia
IPC分类号： C07D417/14 , C07D405/14 , C07D401/12 , C07D401/14 , C07D213/82
CPC分类号： C07D417/14 , A61K31/165 , A61K31/44 , A61K31/497 , C07D213/82 , C07D401/12 , C07D401/14 , C07D405/14 , C07D413/14
摘要： The invention relates to certain compounds or pharmaceutically acceptable salts, solvates, clathrates, or prodrugs thereof, that are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.
摘要翻译： 本发明涉及可用作免疫抑制剂并用于治疗和预防炎性病症，过敏性疾病和免疫疾病的某些化合物或其药学上可接受的盐，溶剂合物，包合物或前药。
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公开(公告)号：US08314134B2
公开(公告)日：2012-11-20
申请号：US12718366
申请日：2010-03-05
申请人： Shoujun Chen , Jun Jiang , Hao Li , David James , Dinesh Chimmanamada , Christopher Borella , Lijun Sun , Yu Xie , Mats Holmqvist , Jerome Mahiou , Zhiqiang Xia
发明人： Shoujun Chen , Jun Jiang , Hao Li , David James , Dinesh Chimmanamada , Christopher Borella , Lijun Sun , Yu Xie , Mats Holmqvist , Jerome Mahiou , Zhiqiang Xia
IPC分类号： C07D235/00 , A01N43/52 , A61K31/415
CPC分类号： A61K31/437 , A61K31/403 , A61K31/4184 , A61K31/4439 , A61K31/444 , A61K31/537 , C07D235/06 , C07D235/08 , C07D235/10 , C07D235/24 , C07D235/28 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/04 , C07D413/14 , C07D417/12 , C07D471/04 , Y02A50/422
摘要： The invention relates to compounds of formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof wherein X, Y, A, Z, L and n are defined herein. These compounds are useful as immunosuppressive agents and for treating and preventing inflammatory conditions and immune disorders.
摘要翻译： 本发明涉及式（I）化合物或其药学上可接受的盐，溶剂合物，包合物或前药，其中X，Y，A，Z，L和n如本文所定义。 这些化合物可用作免疫抑制剂并用于治疗和预防炎性病症和免疫疾病。
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公开(公告)号：US20130142831A1
公开(公告)日：2013-06-06
申请号：US13652878
申请日：2012-10-16
申请人： Shoujun Chen , Jun Jiang , Hao Li , David James , Dinesh Chimmanamada , Christopher Borella , Lijun Sun , Yu Xie , Mats Holmqvist , Jerome Mahiou , Zhiqiang Xia
发明人： Shoujun Chen , Jun Jiang , Hao Li , David James , Dinesh Chimmanamada , Christopher Borella , Lijun Sun , Yu Xie , Mats Holmqvist , Jerome Mahiou , Zhiqiang Xia
IPC分类号： A61K31/437
CPC分类号： A61K31/437 , A61K31/403 , A61K31/4184 , A61K31/4439 , A61K31/444 , A61K31/537 , C07D235/06 , C07D235/08 , C07D235/10 , C07D235/24 , C07D235/28 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/04 , C07D413/14 , C07D417/12 , C07D471/04 , Y02A50/422
摘要： The invention relates to compounds of formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof wherein X, Y, A, Z, L and n are defined herein. These compounds are useful as immunosuppressive agents and for treating and preventing inflammatory conditions and immune disorders.
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公开(公告)号：US20100249195A1
公开(公告)日：2010-09-30
申请号：US12749317
申请日：2010-03-29
申请人： Jun Jiang , Zhi-Qiang Xia , Junyi Zhang , Gary Bohnert , Shoujun Chen , Yu Xie
发明人： Jun Jiang , Zhi-Qiang Xia , Junyi Zhang , Gary Bohnert , Shoujun Chen , Yu Xie
IPC分类号： A61K31/4439 , A61K31/4418 , A61P29/00 , A61P37/00 , C12N5/071 , C12N5/0781 , C12N5/0783
CPC分类号： C07D417/14 , C07D211/70 , C07D211/72 , C07D213/72 , C07D213/75 , C07D213/81 , C07D401/12 , C07D405/10 , C07D409/10 , C07D413/10 , C07D413/14 , C07D417/10 , C07D417/12
摘要： The invention relates to compounds of structural formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof, wherein Y, L, X1, X2, Z, R3, R4, and n are defined herein. These compounds are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.
摘要翻译： 本发明涉及结构式（I）的化合物或其药学上可接受的盐，溶剂合物，包合物或前药，其中Y，L，X1，X2，Z，R3，R4和n如本文所定义。 这些化合物可用作免疫抑制剂并用于治疗和预防炎性病症，过敏性疾病和免疫疾病。
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