公开(公告)号：USD621881S1

公开(公告)日：2010-08-17

申请号：US29313903

申请日：2009-02-17

Applicant: Kurt Youngberg ,  James Wright

Designer： Kurt Youngberg ,  James Wright

公开(公告)号：US20100068285A1

公开(公告)日：2010-03-18

申请号：US12485399

申请日：2009-06-16

Applicant: Stephen E. Zale ,  Greg Troiano ,  Mir Mukkaram Ali ,  Jeff Hrkach ,  James Wright

Inventor： Stephen E. Zale ,  Greg Troiano ,  Mir Mukkaram Ali ,  Jeff Hrkach ,  James Wright

IPC: A61K9/14 ,  A61K31/337 ,  A61K31/439 ,  A61K31/4355

CPC classification number: A61K47/34 ,  A61J3/00 ,  A61K9/10 ,  A61K9/107 ,  A61K9/1647 ,  A61K9/19 ,  A61K9/5146 ,  A61K9/5153 ,  A61K31/337 ,  A61K31/4355 ,  A61K31/436 ,  A61K31/437 ,  A61K31/439 ,  A61K31/475 ,  A61K31/704 ,  A61K31/7068 ,  A61K47/6915 ,  A61K47/6925 ,  A61K47/6937 ,  B82Y5/00 ,  C07C59/08 ,  Y10S977/773

Abstract: The present disclosure generally relates to nanoparticles having about 0.2 to about 35 weight percent of a therapeutic agent; and about 10 to about 99 weight percent of biocompatible polymer such as a diblock poly(lactic) acid-poly(ethylene)glycol. Other aspects of the invention include methods of making such nanoparticles.

Abstract translation: 本公开内容通常涉及具有约0.2至约35重量％的治疗剂的纳米颗粒; 和约10至约99重量％的生物相容性聚合物，例如二嵌段聚（乳酸） - 聚（乙烯）二醇。 本发明的其它方面包括制备这种纳米颗粒的方法。

公开(公告)号：US20080167629A1

公开(公告)日：2008-07-10

申请号：US11861172

申请日：2007-09-25

Applicant: Mitchell Dann ,  Greg Fluet ,  James Wright

Inventor： Mitchell Dann ,  Greg Fluet ,  James Wright

IPC: A61M25/01 ,  A61M25/092

CPC classification number: A61F5/0076 ,  A61F5/0089 ,  A61M25/0074 ,  A61M25/0119 ,  A61M25/0147 ,  A61M25/09041 ,  A61M2025/0024 ,  A61M2025/0079 ,  A61M2025/0681

Abstract: Disclosed herein are elongate flexible medical devices which are capable of axial elongation through the mechanism of eversion or toposcopic expansion. In general, this may be accomplished by providing a flexible tubular device having a proximal end and a distal end. Retraction of the distal end in a proximal direction through the tubular body inverts the tube upon itself, causing an axial shortening of the overall length of the device. The original length of the device can be restored by coupling a pressurized media to the proximal end of the sleeve. If the distal end of the sleeve is temporarily restricted or closed, the pressurized media causes the distal end of the sleeve to travel distally until the full length of the sleeve has been restored.

Abstract translation: 本文公开了伸长的柔性医疗装置，其能够通过外翻或胃肠镜扩张的机制轴向伸长。 通常，这可以通过提供具有近端和远端的柔性管状装置来实现。 远端在近端方向通过管状体的缩回使管自身反转，导致装置的整个长度的轴向缩短。 可以通过将加压介质连接到套筒的近端来恢复装置的原始长度。 如果套筒的远端被暂时限制或关闭，则加压介质使得套筒的远端向远侧行进直到套筒的整个长度恢复。

公开(公告)号：US20080167606A1

公开(公告)日：2008-07-10

申请号：US11861156

申请日：2007-09-25

Applicant: Mitchell Dann ,  Greg Fluet ,  James Wright

Inventor： Mitchell Dann ,  Greg Fluet ,  James Wright

IPC: A61M25/092 ,  A61M29/00 ,  A61M25/09

CPC classification number: A61F5/0076 ,  A61F5/0089 ,  A61M25/0074 ,  A61M25/0119 ,  A61M25/0147 ,  A61M25/09041 ,  A61M2025/0024 ,  A61M2025/0079 ,  A61M2025/0681

Abstract: Disclosed herein are elongate flexible medical devices which are capable of axial elongation through the mechanism of eversion or toposcopic expansion. In general, this may be accomplished by providing a flexible tubular device having a proximal end and a distal end. Retraction of the distal end in a proximal direction through the tubular body inverts the tube upon itself, causing an axial shortening of the overall length of the device. The original length of the device can be restored by coupling a pressurized media to the proximal end of the sleeve. If the distal end of the sleeve is temporarily restricted or closed, the pressurized media causes the distal end of the sleeve to travel distally until the full length of the sleeve has been restored.

Abstract translation: 本文公开了伸长的柔性医疗装置，其能够通过外翻或胃肠镜扩张的机制轴向伸长。 通常，这可以通过提供具有近端和远端的柔性管状装置来实现。 远端在近端方向通过管状体的缩回使管自身反转，导致装置的整个长度的轴向缩短。 可以通过将加压介质连接到套筒的近端来恢复装置的原始长度。 如果套筒的远端被暂时限制或关闭，则加压介质使得套筒的远端向远侧行进直到套筒的整个长度恢复。

公开(公告)号：USD556189S1

公开(公告)日：2007-11-27

申请号：US29227601

申请日：2005-04-13

Applicant: Christopher Bourne ,  James Wright

Designer： Christopher Bourne ,  James Wright

公开(公告)号：US20070246299A1

公开(公告)日：2007-10-25

申请号：US11394575

申请日：2006-03-31

Applicant: James Wright ,  Brian Quinn

Inventor： James Wright ,  Brian Quinn

IPC: E04G3/32

CPC classification number: E04G21/3233 ,  E04G5/14 ,  E04G21/3223 ,  E04G21/3242

Abstract: A stanchion used as part of a regulatory safety barrier around the ledge of an elevated construction slab comprises a square tubular enclosure having an open lower end and a closed upper end. A foot extends orthogonally near the lower end, and rests against the upper surface of the ledge. A clamping member telescopically engaged into the lower end of the enclosure has an arm also extending from its lower extremity and is positioned against the lower surface of the ledge. The arm is urged toward the foot in a ledge-clamping action by the turning of a threaded stem running inside the telescopically engaged enclosure and clamping member. The threaded stem has a lower end captured by a nut welded inside the clamping member. The upper end of the stem protrudes through a hole in the closed end of the enclosure and is fitted with a wing-nut and a hex-nut so that the stem can be turned either by hand or by means of a wrench.

Abstract translation: 作为围绕高架建筑板的突出部分的调节安全屏障的一部分的支柱包括具有敞开的下端和封闭的上端的方形管状外壳。 一只脚在下端附近垂直延伸，并靠在突出部的上表面。 可伸缩地接合到外壳的下端的夹紧构件具有也从其下端延伸并且抵靠突出部的下表面定位的臂。 通过旋转可伸缩接合的外壳和夹紧构件内部的螺纹杆，手臂通过倾斜夹紧动作被推向脚部。 螺纹杆具有通过在夹紧构件内部焊接的螺母捕获的下端。 杆的上端通过外壳封闭端的孔突出，并配有翼形螺母和六角螺母，以便杆可以用手或用扳手转动。

公开(公告)号：US20070198074A1

公开(公告)日：2007-08-23

申请号：US11548605

申请日：2006-10-11

Applicant: Mitchell Dann ,  Joshua Butters ,  Greg Fluet ,  Lee Guterman ,  Jonathan Kagan ,  Paul Swain ,  Gerard Hoffmann ,  James Wright

Inventor： Mitchell Dann ,  Joshua Butters ,  Greg Fluet ,  Lee Guterman ,  Jonathan Kagan ,  Paul Swain ,  Gerard Hoffmann ,  James Wright

IPC: A61F2/06

CPC classification number: A61F5/0076 ,  A61B17/00234 ,  A61B17/0401 ,  A61B17/0482 ,  A61B17/0487 ,  A61B17/0643 ,  A61B17/0644 ,  A61B17/1114 ,  A61B17/12 ,  A61B17/29 ,  A61B2017/00349 ,  A61B2017/00827 ,  A61B2017/0404 ,  A61B2017/0406 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0419 ,  A61B2017/0454 ,  A61B2017/0458 ,  A61B2017/0464 ,  A61B2017/0472 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/0647 ,  A61B2017/0649 ,  A61F2/04 ,  A61F5/0036 ,  A61F5/0086 ,  A61F2002/044

Abstract: The present invention provides devices and methods for attachment of an endolumenal gastrointestinal device, such as an artificial stoma device, a gastrointestinal bypass sleeve or other therapeutic or diagnostic device, within a patient's digestive tract. In one application of the invention, an endolumenal bypass sleeve is removably attached in the vicinity of the gastroesophageal junction to treat obesity and/or its comorbidities, such as diabetes. The bypass sleeve may be at least partially deployed by eversion.

Abstract translation: 本发明提供了用于在患者的消化道内附着腔内胃肠装置的装置和方法，例如人造气道装置，胃肠旁路套管或其他治疗或诊断装置。 在本发明的一个应用中，腹腔内旁路套管可移除地附接在胃食管结合部附近以治疗肥胖症和/或其合并症，例如糖尿病。 旁路套管可以至少部分地通过外翻来展开。

公开(公告)号：US20060151360A1

公开(公告)日：2006-07-13

申请号：US11298948

申请日：2005-12-12

Applicant: James Wright ,  Phillip Hurd ,  Peter Boyer ,  Lisa Arthur ,  Jeffrey Mills ,  Paul Hart ,  Richard Rediger ,  Robbie Kelly

Inventor： James Wright ,  Phillip Hurd ,  Peter Boyer ,  Lisa Arthur ,  Jeffrey Mills ,  Paul Hart ,  Richard Rediger ,  Robbie Kelly

IPC: B03D1/14 ,  B03D1/016 ,  C02F1/56

CPC classification number: C02F1/683 ,  B01D21/0012 ,  B01D21/01 ,  B01D61/14 ,  B03D1/0046 ,  B03D1/01 ,  B03D1/012 ,  B03D1/016 ,  B03D1/02 ,  B03D1/08 ,  B03D3/06 ,  B03D2201/06 ,  B03D2203/006 ,  B03D2203/02 ,  B03D2203/10 ,  B28C1/08 ,  C01P2006/80 ,  C02F1/001 ,  C02F1/24 ,  C02F1/44 ,  C02F1/54 ,  C02F1/56 ,  C02F2101/103 ,  C02F2101/20 ,  C02F2103/10 ,  C02F2103/12 ,  C02F2103/28 ,  C09C1/42 ,  C10G1/045 ,  C10G2300/1003 ,  C10G2300/1033 ,  C10G2300/208 ,  C22B3/24 ,  E21B21/068 ,  Y02P10/234

Abstract: Modified resins are disclosed for removing a wide variety of solids and/or ionic species from the liquids in which they are suspended and/or dissolved. These modified resins are especially useful as froth flotation depressants in the beneficiation of many types of materials (e.g., mineral and metal ores), including the beneficiation of impure coal comprising clay impurities, as well as in the separation of valuable bitumen from solid contaminants such as sand. The modified resins are also useful for treating aqueous liquid suspensions to remove solid particulates, as well as for removing metallic ions in the purification of water. The modified resins comprise a base resin that is modified with a coupling agent, which is highly selective for binding to solid contaminants and especially siliceous materials such as sand or clay.

Abstract translation: 公开了用于从悬浮和/或溶解的液体中除去多种固体和/或离子物质的改性树脂。 这些改性树脂在许多类型的材料（例如矿物和金属矿石）的选矿中特别可用作泡沫浮选抑制剂，包括选择含有粘土杂质的不纯的煤，以及将有价值的沥青从固体污染物分离出来 作为沙子。 改性树脂也可用于处理水性液体悬浮液以除去固体颗粒，以及在净化水中除去金属离子。 改性树脂包括用耦合剂改性的基础树脂，其对于结合固体污染物，特别是硅质材料如沙子或粘土是高选择性的。

公开(公告)号：US07025761B2

公开(公告)日：2006-04-11

申请号：US10241139

申请日：2002-09-10

Applicant: Yulun Wang ,  Darrin R. Uecker ,  Keith Phillip Laby ,  Jeff Wilson ,  Steve Jordan ,  James Wright

Inventor： Yulun Wang ,  Darrin R. Uecker ,  Keith Phillip Laby ,  Jeff Wilson ,  Steve Jordan ,  James Wright

IPC: A61B18/18

CPC classification number: A61B17/11 ,  A61B17/0469 ,  A61B17/29 ,  A61B34/30 ,  A61B34/35 ,  A61B34/37 ,  A61B34/70 ,  A61B34/71 ,  A61B34/72 ,  A61B34/75 ,  A61B34/76 ,  A61B34/77 ,  A61B46/10 ,  A61B50/00 ,  A61B90/361 ,  A61B2017/00199 ,  A61B2017/00243 ,  A61B2017/00252 ,  A61B2017/0046 ,  A61B2017/00477 ,  A61B2017/00703 ,  A61B2017/00973 ,  A61B2017/1107 ,  A61B2017/1135 ,  A61B2017/2927 ,  A61B2017/2929 ,  A61B2034/2059 ,  A61B2034/742 ,  A61B2090/064 ,  B25J9/1689 ,  G05B2219/45119

Abstract: A system for performing minimally invasive cardiac procedures. The system includes a pair of surgical instruments that are coupled to a pair of robotic arms. The instruments have end effectors that can be manipulated to hold and suture tissue. The robotic arms are coupled to a pair of master handles by a controller. The handles can be moved by the surgeon to produce a corresponding movement of the end effectors. The movement of the end effector can be controlled by an input button, so that the end effector only moves when the button is depressed by the surgeon. The input button allows the surgeon to adjust the position of the handles without moving the end effector, so that the handles can be moved to a more comfortable position. The system may also have a robotically controlled endoscope which allows the surgeon to remotely view the surgical site.

Abstract translation: 用于执行微创心脏手术的系统。 该系统包括耦合到一对机器人臂的一对外科器械。 仪器具有能够被操纵以保持和缝合组织的末端效应器。 机器人手臂通过控制器耦合到一对主手柄。 手柄可由外科医生移动以产生末端执行器的相应运动。 端部执行器的运动可以由输入按钮控制，使得当外科医生按下按钮时，末端执行器仅移动。 输入按钮允许外科医生调整手柄的位置而不移动末端执行器，使得手柄可以移动到更舒适的位置。 该系统还可以具有机器人控制的内窥镜，其允许外科医生远程观察手术部位。

公开(公告)号：US20060019939A1

公开(公告)日：2006-01-26

申请号：US11105203

申请日：2005-04-13

Applicant: Julian Adams ,  Yun Gao ,  Asimina Evangelinos ,  Louis Grenier ,  Roger Pak ,  James Porter ,  James Wright

Inventor： Julian Adams ,  Yun Gao ,  Asimina Evangelinos ,  Louis Grenier ,  Roger Pak ,  James Porter ,  James Wright

IPC: A61K31/538 ,  C07D487/02

CPC classification number: A61K31/395 ,  C07D211/60 ,  C07D225/06 ,  C07F9/6561

Abstract: The present invention provides analogs of benzoquinone-containing ansamycins and uses thereof for treating and modulating disorders associated with hyperproliferation, such as cancer. The present invention provides analogs of benzoquinone-containing ansamycins where the benzoquinone is reduced to a hydroquinone and trapped by reaction with a suitable acid, preferably ones that increase the solubility and air stability of the resulting 17-ammonium hydroquinone ansamycin analog.