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145 条记录 (耗时 0.036 秒)

    ULTRASOUND SYNCHRONY MEASUREMENT
    91.
    发明申请
    ULTRASOUND SYNCHRONY MEASUREMENT 审中-公开
    超声波同步测量

    公开(公告)号：US20070161894A1

    公开(公告)日：2007-07-12

    申请号：US11615815

    申请日：2006-12-22

    申请人： Mark Zdeblick ,  Robert White

    发明人： Mark Zdeblick ,  Robert White

    IPC分类号： A61B8/00

    CPC分类号： A61B5/053 ,  A61B5/0051 ,  A61B5/0538

    摘要： Methods for evaluating tissue motion of a tissue location, e.g., a cardiac location, are provided. Aspects of the methods include applying a pressure wave, e.g., ultrasound, to a subject and detecting a change in impedance between two electrodes stably associated with a target site to detect arrival of the pressure wave at said target site and thereby evaluate movement of the target site. Also provided are systems, devices and related compositions for practicing the subject methods. The subject methods and devices find use in a variety of different applications, including cardiac resynchronization therapy.

    摘要翻译： 提供了用于评估组织位置（例如心脏位置）的组织运动的方法。 方法的方面包括对受试者施加压力波，例如超声波，并且检测稳定地与目标部位相关联的两个电极之间的阻抗变化，以检测所述目标部位的压力波的到达，从而评估目标的运动 现场。 还提供了用于实践主题方法的系统，装置和相关组合物。 主题方法和设备可用于各种不同的应用，包括心脏再同步治疗。

    ELECTRICAL ANGLE GAUGE
    92.
    发明申请
    ELECTRICAL ANGLE GAUGE 有权
    电角仪

    公开(公告)号：US20070123944A1

    公开(公告)日：2007-05-31

    申请号：US11555178

    申请日：2006-10-31

    申请人： Mark Zdeblick

    发明人： Mark Zdeblick

    IPC分类号： A61N1/00

    CPC分类号： A61N1/3627 ,  A61N1/36528 ,  A61N1/36578

    摘要： Methods of using electrodes to obtain physiological location motion data are provides. Embodiments of the methods include producing an electrode from a broadcasting electrode that is proximal to the physiological location of interest and detecting a change in an induced electric potential at a receiving electrode to obtain the motion data of interest. Also provided are systems and components thereof, e.g., programming, for practicing methods according to embodiments of the invention.

    摘要翻译： 提供了使用电极获得生理位置运动数据的方法。 所述方法的实施例包括从广播电极产生电极，其接近于感兴趣的生理位置，并检测接收电极处的感应电位的变化以获得感兴趣的运动数据。 还提供了用于根据本发明的实施例的实践方法的系统及其组件，例如编程。

    Pressure sensors having neutral plane positioned transducers
    93.
    发明授权
    Pressure sensors having neutral plane positioned transducers 有权
    压力传感器具有中性平面定位换能器

    公开(公告)号：US07073387B2

    公开(公告)日：2006-07-11

    申请号：US11025795

    申请日：2004-12-28

    申请人： Mark Zdeblick ,  Benedict James Costello

    发明人： Mark Zdeblick ,  Benedict James Costello

    IPC分类号： G01L7/08

    CPC分类号： A61B5/0215 ,  A61B5/412 ,  A61B2562/02 ,  A61N1/3627 ,  A61N1/36564 ,  G01L9/0042 ,  G01L9/0055 ,  G01L9/045 ,  G01L9/065

    摘要： Implantable pressure sensors and methods for making and using the same. A feature of of at least some of the subject pressure sensors is that they are low-drift sensors. Additional features of representable pressure sensors include the presence of a compliant member mounted on a substrate in a manner such that the compliant member has first and second opposing exposed surfaces and is positioned at least proximal to the said pressure sensor's neutral plane. The subject pressure sensors find use in a variety of applications.

    摘要翻译： 可植入压力传感器及其制造和使用方法。 至少一些目标压力传感器的特征在于它们是低漂移传感器。 可表现的压力传感器的附加特征包括以使得柔顺构件具有第一和第二相对的暴露表面并且至少位于所述压力传感器的中立平面附近的方式存在安装在基底上的顺应构件。 主题压力传感器可用于各种应用。

    Pressure sensors having transducers positioned to provide for low drift
    94.
    发明授权
    Pressure sensors having transducers positioned to provide for low drift 有权
    压力传感器具有定位成提供低漂移的换能器

    公开(公告)号：US07007551B2

    公开(公告)日：2006-03-07

    申请号：US11025879

    申请日：2004-12-28

    申请人： Mark Zdeblick ,  Benedict James Costello

    发明人： Mark Zdeblick ,  Benedict James Costello

    IPC分类号： G01L7/08

    CPC分类号： A61B5/0215 ,  A61B5/412 ,  A61B2562/02 ,  A61N1/3627 ,  A61N1/36564 ,  G01L9/0042 ,  G01L9/0055 ,  G01L9/045 ,  G01L9/065

    摘要： Implantable pressure sensors and methods for making and using the same. A feature of of at least some of the subject pressure sensors is that they are low-drift sensors. Additional features of representative pressure sensors include the presence of first and second strain transducers that are associated with a compliant member so that their outputs respond oppositely to deflection of the compliant member resulting from differential pressure across the compliant member but respond similarly to deformation of a substrate on which the compliant member is mounted. The subject pressure sensors find use in a variety of applications.

    摘要翻译： 可植入压力传感器及其制造和使用方法。 至少一些目标压力传感器的特征在于它们是低漂移传感器。 代表性的压力传感器的附加特征包括存在与柔性构件相关联的第一和第二应变传感器，使得它们的输出与穿过柔性构件的差压产生的柔性构件的偏转相反地反应，但是类似于基底的变形 其上安装有柔性构件。 主题压力传感器可用于各种应用。

    Conformal chemically resistant coatings for microflow devices
    96.
    发明授权
    Conformal chemically resistant coatings for microflow devices 失效
    用于微流量装置的保形的耐化学性涂层

    公开(公告)号：US06562404B1

    公开(公告)日：2003-05-13

    申请号：US09645826

    申请日：2000-08-25

    申请人： James A. Folta ,  Mark Zdeblick

    发明人： James A. Folta ,  Mark Zdeblick

    IPC分类号： C23C1634

    CPC分类号： C23C16/045 ,  C23C16/345

    摘要： A process for coating the inside surfaces of silicon microflow devices, such as electrophoresis microchannels, with a low-stress, conformal (uniform) silicon nitride film which has the ability to uniformly coat deeply-recessed cavities with, for example, aspect ratios of up to 40:1 or higher. The silicon nitride coating allows extended exposure to caustic solutions. The coating enables a microflow device fabricated in silicon to be resistant to all classes of chemicals: acids, bases, and solvents. The process involves low-pressure (vacuum) chemical vapor deposition. The ultra-low-stress silicon nitride deposition process allows 1-2 &mgr;m thick films without cracks, and so enables extended chemical protection of a silicon microflow device against caustics for up to 1 year. Tests have demonstrated the resistance of the films to caustic solutions at both ambient and elevated temperatures to 65° C.

    摘要翻译： 用低应力，共形（均匀）氮化硅膜涂覆诸如电泳微通道的硅微流装置的内表面的方法，其具有均匀地涂覆深凹陷空腔的能力，例如具有例如上升的纵横比 至40：1或更高。 氮化硅涂层允许延长暴露于苛性碱溶液。 该涂层使得在硅中制造的微流量装置能够抵抗所有类别的化学品：酸，碱和溶剂。 该方法涉及低压（真空）化学气相沉积。 超低应力氮化硅沉积工艺允许1-2毫米厚的薄膜没有裂缝，因此可以延长硅微流量装置的化学保护，防止焦烧液长达1年。 测试已经证明了膜在环境温度和高温至65℃时对苛性碱溶液的耐受性。

    In-body device having deployable antenna
    100.
    发明授权
    In-body device having deployable antenna 有权
    具有可展开天线的体内装置

    公开(公告)号：US09270025B2

    公开(公告)日：2016-02-23

    申请号：US12530431

    申请日：2008-03-07

    申请人： Timothy Robertson ,  Mark Zdeblick

    发明人： Timothy Robertson ,  Mark Zdeblick

    IPC分类号： A61B5/07 ,  H01Q7/00 ,  A61B5/00 ,  H01Q1/08 ,  H01Q21/20 ,  A61B5/0205 ,  A61B5/11

    CPC分类号： H01Q7/00 ,  A61B5/0031 ,  A61B5/0205 ,  A61B5/073 ,  A61B5/1104 ,  A61B2562/08 ,  H01Q1/08 ,  H01Q21/20

    摘要： Deployable antennas for in-body devices, such as implantable and ingestible devices, are provided. Aspects of the in-body deployable antennas of the invention include antennas configured to go from a first configuration to a second configuration following placement in a living body, e.g., via ingestion or implantation. Embodiments of the in-body devices are configured to emit a detectable signal upon contact with a target physiological site. Also provided are methods of making and using the devices of the invention.

    摘要翻译： 提供用于体内器件的可部署天线，例如可植入和可摄取的设备。 本发明的体内可展开天线的方面包括配置成在放置在生物体中（例如通过摄取或植入）之后从第一配置转到第二配置的天线。 身体内装置的实施例被配置为在与目标生理部位接触时发出可检测信号。 还提供了制造和使用本发明的装置的方法。