T helper cell epitopes
    96.
    发明授权
    T helper cell epitopes 失效
    T辅助细胞表位

    公开(公告)号:US07037507B2

    公开(公告)日:2006-05-02

    申请号:US10935155

    申请日:2004-09-08

    IPC分类号: A61K39/175

    摘要: The present invention provides T helper cell epitopes and compositions for use in inducing an immune response comprising at least one of these epitopes. The epitopes are contained within a peptide sequence selected from the group consisting of SSKTQTHTQQDRPPQPS (SEQ ID NO: 1); QPSTELEETRTSRARHS (SEQ ID NO: 2); QSLRTSLEQSNKAIEEI (SEQ ID NO: 18); and DESSCVFVSESAICSQN (SEQ ID NO: 23).

    摘要翻译: 本发明提供了用于诱导包含这些表位中的至少一个的免疫应答的T辅助细胞表位和组合物。 表位包含在选自SSKTQTHTQQDRPPQPS(SEQ ID NO:1)的肽序列中; QPSTELEETRTSRARHS(SEQ ID NO:2); QSLRTSLEQSNKAIEEI(SEQ ID NO:18); 和DESSCVFVSESAICSQN(SEQ ID NO:23)。

    Accurate blending module and method
    97.
    发明申请
    Accurate blending module and method 有权
    精确的混合模块和方法

    公开(公告)号:US20050273203A1

    公开(公告)日:2005-12-08

    申请号:US11125640

    申请日:2005-05-09

    IPC分类号: G05B21/00 G05D21/02

    CPC分类号: G05D21/02

    摘要: An accurate blending module for adjusting the pH of solutions containing therapeutic proteins includes a recirculation loop that receives the therapeutic protein solution via a feed pump and an acid solution via an adjusting pump. The recirculation loop includes a recirculation pump and a pH sensor that detects the pH of the solution in the recirculation loop. A controller communicates with the pH sensor and the adjusting pump. The adjusting pump adds acid to the recirculation loop based on the pH readings taken by the pH sensor. The recirculation pump recirculates the therapeutic protein solution and acid in the recirculation loop so that it is mixed. As a result, the pH of the therapeutic protein solution is precisely controlled and adjusted in a non-destructive fashion.

    摘要翻译: 用于调节含有治疗性蛋白质的溶液的pH的精确混合模块包括通过经由调节泵的进料泵和酸溶液接收治疗性蛋白质溶液的再循环回路。 再循环回路包括再循环泵和pH传感器,其检测再循环回路中的溶液的pH。 控制器与pH传感器和调节泵通信。 调节泵根据pH传感器采集的pH读数,向再循环回路添加酸。 再循环泵将治疗性蛋白质溶液和酸循环到再循环回路中,使其混合。 结果,治疗性蛋白质溶液的pH被非破坏性地精确地控制和调节。

    Method and apparatus for handling user identities under single sign-on services
    100.
    发明申请
    Method and apparatus for handling user identities under single sign-on services 有权
    在单点登录服务下处理用户身份的方法和装置

    公开(公告)号:US20050154913A1

    公开(公告)日:2005-07-14

    申请号:US10504954

    申请日:2003-02-28

    摘要: An apparatus and method for providing Single Sign-On services to a user when accessing a selected Service Provider from a plurality of Service Providers. An Authentication Provider authenticates the user at with a user-identity, provides the user with a token as proof of the authentication, and assigns a temporary alias-identity to the user for use when the user accesses the selected Service Provider. The Authentication Provider and the selected Service Provider link the assigned alias-identity and the user-identity to identify the user at respective sites. The user accesses the selected Service Provider by presenting the token along with a local user-identity valid for the selected Service Provider. When the user attempts a subsequent access at the selected Service Provider, the user is identified by the shared alias-identity, if the user allowed permanent linking. If the user did not allow permanent linking, the process is repeated for each subsequent access.

    摘要翻译: 一种用于在从多个服务提供商访问所选服务提供商时向用户提供单点登录服务的装置和方法。 认证提供者以用户身份认证用户,向用户提供令牌作为认证的证明,并且向用户分配临时别名身份以供用户访问所选择的服务提供商时使用。 认证提供者和所选择的服务提供商链接所分配的别名身份和用户身份以识别相应站点处的用户。 用户通过呈现令牌以及对所选服务提供商有效的本地用户身份来访问所选择的服务提供商。 当用户尝试在所选服务提供商处的后续访问时,如果用户允许永久链接,则该用户被共享的别名标识。 如果用户不允许永久链接,则对每个后续访问重复该过程。