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公开(公告)号：US20230277746A1
公开(公告)日：2023-09-07
申请号：US17937632
申请日：2022-10-03
发明人： H. David Humes , Deborah Buffington
CPC分类号： A61M1/3687 , A61M1/34 , A61M1/3672 , A61M1/3666 , A61M1/3667 , A61M1/341 , A61M1/3621 , A61M1/3633 , A61M1/3679 , A61M2205/3331
摘要： The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action.
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公开(公告)号：US20230268738A1
公开(公告)日：2023-08-24
申请号：US18140440
申请日：2023-04-27
发明人： Al-Thaddeus Avestruz , Xiaofan Cui , Jason Siegel
CPC分类号： H02J3/32 , H02J3/38 , H02J7/0024 , H02J7/35 , H02J2300/24
摘要： A power conversion device may perform power processing for multiple power nodes coupled in parallel. The power conversion device includes interconnects that couple power nodes to power converters. The power converters include a dense tier of power converters sized to correct, using multiple corrective components, from varied power flow levels to interim power flows for parallel coupling of the multiple power nodes. The power converters also include a sparse tier. The sparse tier performs power processing to convert from the interim power flows generated by the dense tier to a uniform target flow.
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公开(公告)号：US20230266436A1
公开(公告)日：2023-08-24
申请号：US17993421
申请日：2022-11-23
摘要： All existing state-of-the-art high resolution millimeter wave imaging systems experience a trade off between image acquisition time and transceiver array complexity. The proposed dual reflector antenna breaks this trade-off by drastically reducing the array formation time while maintaining the relative simplicity that comes with using a single transceiver element. It consists of a dual mode horn feed, a rotating ellipsoidal sub-reflector and a conic main reflector. The rotating sub-reflector creates a virtual phase center that rotates about an axis to produce a synthetic circular array with a diameter of 120λ. The main reflector redirects the beams from each of these virtual phase centers to overlap and illuminate the scene over a wide field of view. The proposed system can reduce the image acquisition time to the order of milliseconds/seconds which makes real-time SAR imaging a practical alternative to MIMO and phased arrays at millimeter-wave and sub-millimeter-wave frequencies.
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公开(公告)号：US20230263785A1
公开(公告)日：2023-08-24
申请号：US18041059
申请日：2021-08-10
发明人： Paul Swiecicki , J. Chad Brenner
IPC分类号： A61K31/44 , C12Q1/6886 , A61K45/06 , C07K16/22 , A61K31/47 , A61K31/404 , A61K31/506
CPC分类号： A61K31/44 , C12Q1/6886 , A61K45/06 , C07K16/22 , A61K31/47 , A61K31/404 , A61K31/506 , C12Q2600/106 , C12Q2600/156
摘要： The disclosure provides methods for treating cancer with a receptor tyrosine kinase (RTK) inhibitor by first selecting a subject for treatment that has a mutation in one or more genes involved in the phosphoinositide 3-kinase (PI3K) signaling pathway, followed by administering the RTK inhibitor to the selected subject.
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公开(公告)号：US11724736B2
公开(公告)日：2023-08-15
申请号：US17341598
申请日：2021-06-08
发明人： Douglas Scott Rhode , David Dean Smit , Erick Michael Lavoie , Martin Fitzpatrick Frey , Thomas Edward Pilutti , Taehyun Shim , Matt Y. Rupp , Roger Arnold Trombley
CPC分类号： B62D13/06 , B62D1/22 , B62D15/027 , B60W30/06 , B60W30/18036 , B60W2300/14 , B60W2520/22 , B60W2710/207 , B60Y2200/147
摘要： A vehicle has a trailer backup steering input apparatus, a trailer backup assist control module coupled to the a trailer backup steering input apparatus, and an electric power assist steering system coupled to the trailer backup assist control module. The trailer backup steering input apparatus is configured for outputting a trailer path curvature signal approximating a desired curvature for a path of travel of a trailer towably coupled to the vehicle. The trailer backup assist control module is configured for determining vehicle steering information as a function of the trailer path curvature signal. The electric power assist steering system is configured for controlling steering of steered wheels of the vehicle as a function of the vehicle steering information.
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公开(公告)号：US11719778B1
公开(公告)日：2023-08-08
申请号：US17589780
申请日：2022-01-31
申请人： REGENTS OF THE UNIVERSITY OF MICHIGAN , CASE WESTERN RESERVE UNIVERSITY , UNIVERSITY HOSPITALS CLEVELAND MEDICAL CENTER
IPC分类号： G01R33/56 , G01R33/50 , A61B5/00 , A61B5/055 , G01R33/483
CPC分类号： G01R33/5608 , A61B5/0044 , A61B5/055 , G01R33/483 , G01R33/50
摘要： Methods and systems generate synthetic late gadolinium enhancement (LGE) magnetic resonance images using a magnetic resonance fingerprinting (MRF) acquisition. From a single acquisition, MRF image data is obtained, including co-registered T1 and T2 tissue property maps. Different tissue regions of interest are identified, such as viable myocardium, scar, and blood and T1 and T2 values for each are determined. Based on these, different sets of pulse sequence parameters are determined, e.g., using different synthetic image contrast models receiving the MRF image data. Synthetic LGE images at different contrasts are generated as a result, including a synthetic bright-blood LGE image, a synthetic dark-blood/gray-blood LGE image, and a synthetic optimized imaged.
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97.发明公开公开(公告)号：US20230243909A1
公开(公告)日：2023-08-03
申请号：US17589780
申请日：2022-01-31
申请人： REGENTS OF THE UNIVERSITY OF MICHIGAN , CASE WESTERN RESERVE UNIVERSITY , UNIVERSITY HOSPITALS CLEVELAND MEDICAL CENTER
IPC分类号： G01R33/56 , G01R33/50 , G01R33/483 , A61B5/055 , A61B5/00
CPC分类号： G01R33/5608 , G01R33/50 , G01R33/483 , A61B5/055 , A61B5/0044
摘要： Methods and systems generate synthetic late gadolinium enhancement (LGE) magnetic resonance images using a magnetic resonance fingerprinting (MRF) acquisition. From a single acquisition, MRF image data is obtained, including co-registered T1 and T2 tissue property maps. Different tissue regions of interest are identified, such as viable myocardium, scar, and blood and T1 and T2 values for each are determined. Based on these, different sets of pulse sequence parameters are determined, e.g., using different synthetic image contrast models receiving the MRF image data. Synthetic LGE images at different contrasts are generated as a result, including a synthetic bright-blood LGE image, a synthetic dark-blood/gray-blood LGE image, and a synthetic optimized imaged.
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公开(公告)号：US11712889B2
公开(公告)日：2023-08-01
申请号：US17396043
申请日：2021-08-06
发明人： Brian Iezzi , Max Shtein , Zahra Afkhami Kheirabadi , Kira Barton
CPC分类号： B41J2/06 , B41J11/00214 , G03F7/2018 , H01L33/46
摘要： A method of fabricating a thin film structure includes printing, using an electrohydrodynamic jet (e-jet) printing apparatus, a first layer comprising a first liquid ink, such that the first layer is supported by a substrate, curing the first layer; printing, using the e-jet printing apparatus, a second layer comprising a second liquid ink, such that the second layer is supported by the first layer, and curing the second layer.
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99.发明公开公开(公告)号：US20230236271A1
公开(公告)日：2023-07-27
申请号：US18097632
申请日：2023-01-17
CPC分类号： G01R33/4826 , G06T5/20 , G06T5/002 , G06T11/008 , G06T2207/20081 , G06T2207/20084 , G06T2210/41 , G06T2207/10088 , G06T2207/30016
摘要： The following relates generally to accelerated magnetic resonance imaging (MRI) reconstruction. In some embodiments, a MRI machine learning algorithm is trained based on reference MRI data in non-Cartesian k-space. During the training, at each iteration of a plurality of iterations: (i) a non-Cartesian sampling trajectory ω may be optimized under the physical constraints, and/or (ii) an image reconstructor may be jointly iteratively optimized. Examples of the image reconstructor include a convolutional neural network (CNN) denoiser, a model-based deep learning (MoDL) image reconstructor, iterative image reconstructor, a regularizer, and an invertible neural network.
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公开(公告)号：US20230234028A1
公开(公告)日：2023-07-27
申请号：US18070525
申请日：2022-11-29
CPC分类号： B01J20/265 , B01J20/28028 , B01J20/3085 , C08F20/06 , C08J11/28 , C02F1/285 , B01D53/0407 , C08F2810/00 , C08J2333/02 , C02F2101/32
摘要： Articles comprising pressure-sensitive adhesives and methods of their use for removing micro- and nanoplastic particles from various media, including wastewater effluent, laundry effluent, and indoor air, are disclosed.
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