公开(公告)号：US20050042341A1

公开(公告)日：2005-02-24

申请号：US10820147

申请日：2004-04-08

Applicant: Linda Thomas ,  Sebastien Gouin ,  Kathryn Tse ,  Carsten Hansen

Inventor： Linda Thomas ,  Sebastien Gouin ,  Kathryn Tse ,  Carsten Hansen

IPC: A21D2/00 ,  A23B4/10 ,  A23B4/12 ,  A23B4/20 ,  A23B4/22 ,  A23B5/06 ,  A23B5/14 ,  A23B5/16 ,  A23C19/084 ,  A23C19/11 ,  A23L1/00 ,  A23L1/30 ,  A23L1/318 ,  A23L2/52 ,  A23L3/3463 ,  A23L3/3472 ,  A23L3/3544 ,  A23L3/3571 ,  B01J13/04 ,  B01J13/08 ,  B01J13/22 ,  C12H1/10

CPC classification number: A23C19/084 ,  A21D2/00 ,  A23B4/10 ,  A23B4/12 ,  A23B4/20 ,  A23B4/22 ,  A23B5/06 ,  A23B5/14 ,  A23B5/16 ,  A23C19/11 ,  A23L2/52 ,  A23L3/34635 ,  A23L3/3472 ,  A23L3/3544 ,  A23L3/3571 ,  A23L13/72 ,  A23L33/127 ,  A23L33/135 ,  A23P10/30 ,  A23P10/35 ,  A23V2002/00 ,  B01J13/043 ,  B01J13/08 ,  B01J13/22 ,  Y02A40/946 ,  A23V2200/224 ,  A23V2200/10

Abstract: The present invention relates to a novel natamycin dosage form for the food industry, and more particularly to microcapsules where natamycin is encapsulated within a physiologically acceptable shell to provide a protected natamycin product. The present invention relates also to novel processes for preparing the capsules according to the invention, as well as to the use of the capsules of the present invention. The invention further relates to food products containing natamycin in encapsulated form.

Abstract translation: 本发明涉及一种用于食品工业的新型纳他霉素剂型，更具体地涉及其中游霉素封装在生理学上可接受的壳内以提供受保护的纳他霉素产品的微胶囊。 本发明还涉及制备根据本发明的胶囊的新方法以及本发明胶囊的用途。 本发明还涉及含有包囊形式的游霉素的食品。

公开(公告)号：US20040175328A1

公开(公告)日：2004-09-09

申请号：US10804679

申请日：2004-03-18

Inventor： Andrew D. Sutton ,  Richard A. Johnson ,  Peter J. Senior ,  David Heath

IPC: A61K049/00 ,  A61K009/16 ,  A61K009/50

CPC classification number: A61K9/0075 ,  A61K9/1688 ,  A61K9/1694 ,  A61K9/5089 ,  A61K49/00 ,  A61K49/223 ,  A61K49/225 ,  B01J13/04 ,  B01J13/043 ,  B01J13/14 ,  Y10S514/965

Abstract: Microparticles of a water-soluble material, which are smooth and spherical, and at least 90% of which have a mass median particle size of 1 to 10 nullm, and which carry a therapeutic or diagnostic agent can successfully be used in dry powder inhalers to deliver the said agent.

Abstract translation: 水溶性材料的微粒，其光滑和球形，其至少90％的质量中值粒径为1-10μm，并且携带治疗或诊断剂可以成功地用于干粉吸入器 交付该代理。

公开(公告)号：US06723359B2

公开(公告)日：2004-04-20

申请号：US09982648

申请日：2001-10-18

Applicant: Anandaraman Subramaniam ,  Robert Clark McIver ,  Florin Joseph Vlad ,  Daniel Benczedi

Inventor： Anandaraman Subramaniam ,  Robert Clark McIver ,  Florin Joseph Vlad ,  Daniel Benczedi

IPC: A23L1216

CPC classification number: C11D3/221 ,  A23G3/346 ,  A23G2200/00 ,  A23L3/46 ,  A23L27/70 ,  A23P10/30 ,  A23V2002/00 ,  B01J13/043 ,  C11D3/222 ,  C11D3/505 ,  C11D11/02 ,  A23V2200/224 ,  A23V2250/5114 ,  A23V2250/628 ,  A23V2250/5024 ,  A23V2250/1862 ,  A23V2250/1842

Abstract: The invention relates to a spray-dried composition comprising an active ingredient dispersed in a carrier comprising a combination of a wall-forming carbohydrate material with from 1 to 30% by weight of agar agar relative to the dried weight of the composition. The composition of the invention provides advantageous behavior in an aqueous environment wherein the mobility of the active agent is restricted in the gelled carrier, thus preventing the release of the agent unless shear of heat are applied. Another feature of the invention is a process for the preparation the spray-dried composition.

Abstract translation: 本发明涉及一种喷雾干燥的组合物，其包含分散在载体中的活性成分，其包含壁形成碳水化合物材料与1至30重量％琼脂琼脂相对于组合物干重的组合。 本发明的组合物在水性环境中提供有利的行为，其中活性剂的迁移率在胶凝载体中受到限制，因此除非施加热量，否则防止了试剂的释放。 本发明的另一个特征是制备喷雾干燥组合物的方法。

公开(公告)号：US5863862A

公开(公告)日：1999-01-26

申请号：US749744

申请日：1996-11-15

Applicant: Herbert Eck ,  Heinrich Hopf ,  Gerald Fleischmann ,  Ernst Innertsberger ,  Jakob Schmidlkofer

Inventor： Herbert Eck ,  Heinrich Hopf ,  Gerald Fleischmann ,  Ernst Innertsberger ,  Jakob Schmidlkofer

IPC: C09D7/12 ,  A01N25/28 ,  A61K9/50 ,  B01J13/04 ,  B01J13/12 ,  C04B20/10 ,  C08J3/14 ,  C08K9/08 ,  C08K9/10 ,  A23L3/42 ,  A61K7/46

CPC classification number: B01J13/043 ,  Y10S514/82

Abstract: The invention relates to a process for the preparation of microcapsulated flakes or powders by drying aqueous mixtures containing (a) one or more water-emulsifiable, non-thermoplastic compounds which have a higher boiling point than waterand (b) at least one water-soluble, film-forming polymer, in which the content of component (a) is up to about 95% by weight, based on the dry weight of components (a) and (b), with the proviso that the water-soluble, film-forming polymer has a flocculation point of from 20.degree. to 98.degree. C. or the flocculation point is adjusted to from 20.degree. to 98.degree. C. with the aid of additives, and drying is carried out by thin-layer drying in a temperature range above the flocculation point.

Abstract translation: 本发明涉及通过干燥含有（a）一种或多种具有比水高沸点的水可乳化的非热塑性化合物的水性混合物来制备微胶囊化的薄片或粉末的方法，（b）至少一种水溶性 成膜聚合物，其中组分（a）的含量基于组分（a）和（b）的干重为至多约95重量％，条件是水溶性， 絮凝点为20〜98℃，絮凝点借助添加剂调节至20〜98℃，通过薄层干燥在温度范围内进行干燥 高于絮凝点。

公开(公告)号：US5492701A

公开(公告)日：1996-02-20

申请号：US272337

申请日：1994-07-08

Applicant: Eric Cervos ,  Pierre Labourt-Ibarre ,  Jean-Claude Le Thiesse ,  Eraclis Statiotis

Inventor： Eric Cervos ,  Pierre Labourt-Ibarre ,  Jean-Claude Le Thiesse ,  Eraclis Statiotis

IPC: A61J3/07 ,  A61K9/14 ,  A61K9/50 ,  A61K47/42 ,  B01J13/02 ,  B01J13/04

CPC classification number: B01J13/043

Abstract: An oil-in-water emulsion is passed through a nozzle to form spherules which are allowed to fall countercurrent to a flow of cold air and which are recovered utilizing either a liquid crosslinking agent or a solution, preferably aqueous, optionally containing a crosslinking agent.

Abstract translation: 将水包油乳液通过喷嘴形成小球，所述小球被允许与冷空气流逆流并且使用任选含有交联剂的液体交联剂或溶液，优选水溶液回收。

公开(公告)号：US5091122A

公开(公告)日：1992-02-25

申请号：US173071

申请日：1988-03-24

Applicant: David R. Friend

Inventor： David R. Friend

IPC: B01J13/02 ,  B01J13/04 ,  B01J13/14

CPC classification number: B01J13/14 ,  B01J13/043 ,  Y10T428/2987

Abstract: A method of preparing microencapsulated basic solutions including the steps of preparing a polymer which is hydrophobic at high pH values, preparing a basic solution, dissolving the polymer in an organic solvent, adding a surfactant to the polymer solution, adding the basic solution to the dissolved polymer, emulsifying the basic solution and dissolved polymer and spray drying the emulsion while stirring the emulsion.

Abstract translation: 一种制备微胶囊化碱性溶液的方法，包括制备在高pH值下为疏水性的聚合物的步骤，制备碱性溶液，将聚合物溶解在有机溶剂中，向聚合物溶液中加入表面活性剂，将碱溶液加入到溶解的 聚合物，乳化碱性溶液和溶解的聚合物，并在搅拌乳液的同时喷雾干燥乳液。

公开(公告)号：US5043280A

公开(公告)日：1991-08-27

申请号：US287918

申请日：1988-12-21

Applicant: Wilfried Fischer ,  Bernd W. Muller

Inventor： Wilfried Fischer ,  Bernd W. Muller

IPC: A61J3/00 ,  A61J3/06 ,  A61J3/07 ,  A61K9/16 ,  A61K9/18 ,  A61K9/22 ,  A61K9/26 ,  B01J13/04

CPC classification number: A61K9/1694 ,  B01J13/043

Abstract: A sterile product containing a substance embedded in a carrier is produced by use of a supercritical gas. In one embodiment, a mixture is formed of a substance, carrier and supercritical gas such as nitrous oxide or carbon dioxide, and the supercritical gas is separated from the substance and carrier to obtain the product. In another embodiment, the supercritical gas contains the substance, and is mixed with an atomized organic solvent containing the carrier to form a mixture. The supercritical gas extracts the solvent, and is separated from the substance and carrier to produce the product. Alternatively, the carrier can be in the supercritical gas and the substance in the solvent, or both the substance and carrier can be in the solvent. Atomization and formation of the mixture can be carried out by feeding the supercritical gas and solvent through a nozzle into a spray tower or column. The supercritical gas containing the solvent is separated to obtain the product in the form of a dry powder containing spheres of the carrier having the substance embedded therein. The carrier can be polymers, lipids, lecithins or waxes, and the substance can be medicines, toxins, viruses, diagnostic materials, herbicides, insecticides or pesticides. An apparatus for carrying out the method contains a spray tower and other means for performing the method steps.

Abstract translation: 通过使用超临界气体制备含有嵌入载体中的物质的无菌产品。 在一个实施方案中，由物质，载体和超临界气体如一氧化二氮或二氧化碳形成混合物，并且超临界气体与物质和载体分离以获得产物。 在另一个实施方案中，超临界气体含有物质，并与含有载体的雾化有机溶剂混合以形成混合物。 超临界气体提取溶剂，并与物质和载体分离以产生产物。 或者，载体可以在超临界气体中，溶剂中的物质，或物质和载体都可以在溶剂中。 混合物的雾化和形成可以通过将超临界气体和溶剂通过喷嘴进料到喷雾塔或塔中来进行。 分离含有溶剂的超临界气体，得到含有嵌入物质的载体球的干粉形式的产物。 载体可以是聚合物，脂质，卵磷脂或蜡，该物质可以是药物，毒素，病毒，诊断材料，除草剂，杀虫剂或杀虫剂。 用于执行该方法的装置包括喷雾塔和用于执行方法步骤的其它装置。

公开(公告)号：US4588612A

公开(公告)日：1986-05-13

申请号：US726408

申请日：1985-04-24

Applicant: Douglas W. Perkins ,  Anthony V. Petricca

Inventor： Douglas W. Perkins ,  Anthony V. Petricca

IPC: A23G3/34 ,  A23L1/00 ,  A23L1/22 ,  A23L1/236 ,  A23P1/04 ,  A61K9/50 ,  B01J8/24 ,  B01J13/04 ,  B05D1/22

CPC classification number: B01J13/043 ,  A23G3/346 ,  A23L27/32 ,  A23L27/72 ,  A23P10/35 ,  A61K9/50 ,  B01J8/1872 ,  A23G2220/20

Abstract: A process for encapsulating materials which are difficult to fluidize in a fluidized bed reactor comprising the steps of (1) compacting said materials into a plurality of flat chips; (2) grinding said chips into particles having a small particle size; (3) forming a fluid bed of the particles of step (2) in a fluid bed spray reactor; (4) applying a spray of a melted or molten hydrogenated liquid or wax to the surface of said particles in said reactor, encapsulating said particles; withdrawing said encapsulating material from said reactor.

Abstract translation: 一种用于封装在流化床反应器中难以流化的材料的方法，包括以下步骤：（1）将所述材料压实成多个平的芯片; （2）将所述切屑研磨成粒径小的颗粒; （3）在流化床喷雾反应器中形成步骤（2）的颗粒的流化床; （4）将熔融或熔化的氢化液体或蜡的喷雾施加到所述反应器中的所述颗粒的表面上，封装所述颗粒; 从所述反应器中抽出所述封装材料。

公开(公告)号：US4123381A

公开(公告)日：1978-10-31

申请号：US766729

申请日：1977-02-08

Applicant: Masataka Morishita ,  Mitsuru Fukushima ,  Tutomu Sasagawa ,  Yoshihito Inaba ,  Yasuo Yokokawa ,  Satoshi Araragi ,  Narumi Yoshida ,  Hachiro Uchiyama

Inventor： Masataka Morishita ,  Mitsuru Fukushima ,  Tutomu Sasagawa ,  Yoshihito Inaba ,  Yasuo Yokokawa ,  Satoshi Araragi ,  Narumi Yoshida ,  Hachiro Uchiyama

IPC: B01J13/04 ,  B01J13/08 ,  B01J20/28 ,  B01J13/02

CPC classification number: B01J20/28026 ,  B01J13/043 ,  B01J13/08 ,  B01J20/28004 ,  B01J20/2805 ,  B01J20/28078 ,  Y10T428/2989

Abstract: A cellulose microcapsule having absorbing capacity, consisting of outer semipermeable barrier layer of cellulose and absorbent powders dispersed within inner cellulose gel matrix is prepared by dispersing adsorbent powders in a solution of cellulose dissolved in a solvent which is not adversely affected by the adsorbing capacity of adsorbent powders and capable of dissolving cellulose, then forming the dispersion into droplets and finally precipitating cellulose on the droplets. It is excellent in resistance to chemicals such as acids, alkalis or organic solvents and is useful for various purposes.

Abstract translation: 具有吸收能力的纤维素微胶囊由纤维素的外部半透性阻隔层和分散在内部纤维素凝胶基质内的吸收性粉末组成，通过将吸附剂粉末分散在溶解在溶剂中的纤维素溶液中而不受吸附剂的吸附能力的不利影响 粉末并能够溶解纤维素，然后将分散体形成液滴并最终在纤维素上沉淀纤维素。 它对耐酸性，碱性或有机溶剂的耐化学性是优异的，可用于各种目的。

公开(公告)号：US20240316523A1

公开(公告)日：2024-09-26

申请号：US18609358

申请日：2024-03-19

Applicant: The Procter & Gamble Company

Inventor： Patricia ANDREU

IPC: B01J13/04 ,  C11B9/00

CPC classification number: B01J13/043 ,  C11B9/00

Abstract: The present invention relates to a process of making a salted spray-dried perfume microcapsule particle.