公开(公告)号：US20170342404A1

公开(公告)日：2017-11-30

申请号：US15470814

申请日：2017-03-27

Applicant: 10X GENOMICS, INC.

Inventor： Benjamin Hindson ,  Serge Saxonov ,  Kevin Ness ,  Paul Hardenbol ,  Christopher Hindson ,  Donald Masquelier ,  Mirna Jarosz ,  Michael Schnall-Levin

IPC: C12N15/10 ,  C12Q1/68 ,  C12N15/11 ,  G01N33/543

CPC classification number: C12N15/1065 ,  C12N15/11 ,  C12Q1/6806 ,  C12Q1/6874 ,  C12Q1/6876 ,  C12Q2600/112 ,  G01N33/5436

Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.

公开(公告)号：US20170159109A1

公开(公告)日：2017-06-08

申请号：US15367660

申请日：2016-12-02

Applicant: 10X Genomics, Inc.

Inventor： Xinying ZHENG ,  Serge Saxonov ,  Michael Schnall-Levin ,  Kevin Ness ,  Rajiv Bharadwaj

IPC: C12Q1/68

CPC classification number: C12Q1/6809 ,  C12Q1/6806 ,  C12Q1/6834 ,  C12Q1/6869 ,  C12Q2521/501 ,  C12Q2523/101 ,  C12Q2525/155 ,  C12Q2525/191 ,  C12Q2535/122 ,  C12Q2543/101 ,  C12Q2563/149 ,  C12Q2563/159 ,  C12Q2563/179 ,  C12Q2565/631

Abstract: The present invention is directed to methods, compositions and systems for analyzing sequence information while retaining structural and molecular context of that sequence information.

公开(公告)号：US09567631B2

公开(公告)日：2017-02-14

申请号：US14104650

申请日：2013-12-12

Applicant: 10X Genomics, Inc.

Inventor： Benjamin Hindson ,  Serge Saxonov ,  Kevin Ness ,  Paul Hardenbol

IPC: C12Q1/68

CPC classification number: C12Q1/6874 ,  C12Q1/6806 ,  C12Q1/683 ,  C12Q2525/191 ,  C12Q2537/143 ,  C12Q2563/179

Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.

Abstract translation: 本公开提供了用于多核苷酸处理的组合物，方法，系统和装置。 这种多核苷酸处理可用于多种应用，包括多核苷酸测序。

公开(公告)号：US12138628B2

公开(公告)日：2024-11-12

申请号：US17397146

申请日：2021-08-09

Applicant: 10x Genomics, Inc.

Inventor： Rajiv Bharadwaj ,  Kevin Ness ,  Tobias Daniel Wheeler

IPC: B01L3/00 ,  G01N1/28 ,  G01N33/487

Abstract: Microfluidic channels networks and systems are provided. One network includes a first fluid channel having a first depth dimension; at least a second channel intersecting the first channel at a first intersection; at least a third channel in fluid communication with the first intersection, at least one of the first intersection and the third channel having a depth dimension that is greater than the first depth dimension. Also provided is a flow control system for directing fluids in the network. Systems are additionally provided for flowing disrupted particles into a droplet formation junction, whereby a portion of the disrupted particles or the contents thereof are encapsulated into one or more droplets. Further provided is a method for controlling filling of a microfluidic network by controlling passive valving microfluidic channel network features.

公开(公告)号：US20240336967A1

公开(公告)日：2024-10-10

申请号：US18377068

申请日：2023-10-05

Applicant: 10X GENOMICS, INC.

Inventor： Benjamin Hindson ,  Mirna Jarosz ,  Paul Hardenbol ,  Michael Schnall-Levin ,  Kevin Ness ,  Serge Saxonov

IPC: C12Q1/6874 ,  C12N15/00 ,  C12N15/10 ,  C12Q1/6806 ,  C12Q1/683

CPC classification number: C12Q1/6874 ,  C12N15/00 ,  C12N15/10 ,  C12N15/1093 ,  C12Q1/683 ,  C12Q1/6806 ,  C12Q2525/191 ,  C12Q2537/143 ,  C12Q2563/179

Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing. In some cases, this disclosure provides methods for the generation of polynucleotide barcode libraries, and for the attachment of such polynucleotides to target polynucleotides.

公开(公告)号：US11873528B2

公开(公告)日：2024-01-16

申请号：US17943064

申请日：2022-09-12

Applicant: 10X GENOMICS, INC.

Inventor： Xinying Zheng ,  Serge Saxonov ,  Michael Schnall-Levin ,  Kevin Ness ,  Rajiv Bharadwaj

IPC: C12Q1/6809 ,  C12Q1/6806 ,  C12Q1/6834 ,  C12Q1/6869

CPC classification number: C12Q1/6809 ,  C12Q1/6806 ,  C12Q1/6834 ,  C12Q1/6869 ,  C12Q1/6806 ,  C12Q2521/501 ,  C12Q2523/101 ,  C12Q2525/155 ,  C12Q2525/191 ,  C12Q2535/122 ,  C12Q2543/101 ,  C12Q2563/149 ,  C12Q2563/159 ,  C12Q2563/179 ,  C12Q2565/631 ,  C12Q1/6869 ,  C12Q2521/501 ,  C12Q2523/101 ,  C12Q2525/155 ,  C12Q2525/191 ,  C12Q2535/122 ,  C12Q2543/101 ,  C12Q2563/149 ,  C12Q2563/159 ,  C12Q2563/179 ,  C12Q2565/631

Abstract: The present invention is directed to methods, compositions and systems for analyzing sequence information while retaining structural and molecular context of that sequence information.

公开(公告)号：US20240002837A1

公开(公告)日：2024-01-04

申请号：US18367638

申请日：2023-09-13

Applicant: 10x Genomics, Inc.

Inventor： Benjamin Hindson ,  Christopher Hindson ,  Michael Schnall-Levin ,  Kevin Ness ,  Mirna Jarosz ,  Serge Saxonov ,  Paul Hardenbol ,  Rajiv Bharadwaj ,  Xinying Zheng ,  Phillip Belgrader

IPC: C12N15/10 ,  C40B20/04 ,  C12Q1/6804 ,  C12Q1/6806 ,  C40B50/16 ,  C12Q1/6874 ,  C12Q1/683

CPC classification number: C12N15/1065 ,  C40B20/04 ,  C12Q1/6804 ,  C12Q1/6806 ,  C40B50/16 ,  C12Q1/6874 ,  C12Q1/683 ,  C12Q2537/143 ,  C12Q2525/191 ,  C12Q2565/629 ,  C12Q2563/159 ,  C12Q2563/179 ,  C12Q2537/149 ,  C12Q2535/122 ,  C12Q2563/149

Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.

公开(公告)号：US20230348897A1

公开(公告)日：2023-11-02

申请号：US18207023

申请日：2023-06-07

Applicant: 10x Genomics, Inc.

Inventor： Benjamin Hindson ,  Christopher Hindson ,  Michael Schnall-Levin ,  Kevin Ness ,  Mirna Jarosz ,  Serge Saxonov

IPC: C12N15/10 ,  C40B50/16 ,  C40B20/04 ,  C12Q1/6804 ,  C12Q1/6806 ,  C12Q1/683 ,  C12Q1/6874

CPC classification number: C12N15/1065 ,  C40B50/16 ,  C40B20/04 ,  C12Q1/6804 ,  C12Q1/6806 ,  C12Q1/683 ,  C12Q1/6874 ,  C12Q2525/191 ,  C12Q2535/122 ,  C12Q2537/143 ,  C12Q2537/149 ,  C12Q2563/149 ,  C12Q2563/159 ,  C12Q2563/179 ,  C12Q2565/629

Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.

公开(公告)号：US11421274B2

公开(公告)日：2022-08-23

申请号：US16852906

申请日：2020-04-20

Applicant: 10X Genomics, Inc.

Inventor： Benjamin Hindson ,  Serge Saxonov ,  Kevin Ness ,  Paul Hardenbol ,  Michael Schnall-Levin ,  Mirna Jarosz

IPC: C12Q1/6806 ,  C12Q1/6855 ,  C12Q1/6869 ,  C12Q1/6874

Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.

公开(公告)号：US20220154175A1

公开(公告)日：2022-05-19

申请号：US17517287

申请日：2021-11-02

Applicant: 10x Genomics, Inc.

Inventor： Benjamin Hindson ,  Serge Saxonov ,  Kevin Ness ,  Paul Hardenbol ,  Christopher Hindson ,  Donald Masquelier ,  Mirna Jarosz ,  Michael Schnall-Levin

IPC: C12N15/10 ,  C12Q1/6806 ,  C12N15/11 ,  G01N33/543 ,  C12Q1/6876 ,  C12Q1/6874

Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.