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公开(公告)号：US20250146047A1
公开(公告)日：2025-05-08
申请号：US18960947
申请日：2024-11-26
Applicant: 10x Genomics, Inc.
Inventor： Benjamin Hindson , Christopher Hindson , Michael Schnall-Levin , Kevin Ness , Mirna Jarosz , Donald Masquelier , Serge Saxonov , Landon Merrill , Andrew Price , Paul Hardenbol , Yuan Li
IPC: C12Q1/6806 , C12N15/10
Abstract: This disclosure provides methods and compositions for sample processing, particularly for sequencing applications. Included within this disclosure are bead compositions, such as diverse libraries of beads attached to large numbers of oligonucleotides containing barcodes. Often, the beads provides herein are degradable. For example, they may contain disulfide bonds that are susceptible to reducing agents. The methods provided herein include methods of making libraries of barcoded beads as well as methods of combining the beads with a sample, such as by using a microfluidic device.
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公开(公告)号：US10150963B2
公开(公告)日：2018-12-11
申请号：US15470814
申请日：2017-03-27
Applicant: 10X GENOMICS, INC.
Inventor： Benjamin Hindson , Serge Saxonov , Kevin Ness , Paul Hardenbol , Christopher Hindson , Donald Masquelier , Mirna Jarosz , Michael Schnall-Levin
IPC: C12N15/10 , C12Q1/6806 , C12N15/11 , C12Q1/6876 , G01N33/543 , C12Q1/6874
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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3.发明申请公开(公告)号：US20180008984A1
公开(公告)日：2018-01-11
申请号：US15687856
申请日：2017-08-28
Applicant: 10X Genomics, Inc.
Inventor： Rajiv Bharadwaj , Kevin Ness , Debkishore Mitra , Donald Masquelier , Anthony Makarewicz , Christopher Hindson , Benjamin Hindson , Serge Saxonov
CPC classification number: B01L3/502761 , B01L3/0241 , B01L3/502784 , B01L2200/0673 , B01L2300/0816 , B01L2400/049 , B01L2400/086 , G01N35/085 , G01N2035/00237 , G01N2035/1034
Abstract: The disclosure provides devices, systems and methods for the generation of encapsulated reagents and the partitioning of encapsulated reagents for use in subsequent analyses and/or processing, such as in the field of biological analyses and characterization.
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公开(公告)号：US10150117B2
公开(公告)日：2018-12-11
申请号：US15717847
申请日：2017-09-27
Applicant: 10X Genomics, Inc.
Inventor： Rajiv Bharadwaj , Kevin Ness , Debkishore Mitra , Donald Masquelier , Anthony Makarewicz , Christopher Hindson , Benjamin Hindson , Serge Saxonov
Abstract: The disclosure provides devices, systems and methods for the generation of encapsulated reagents and the partitioning of encapsulated reagents for use in subsequent analyses and/or processing, such as in the field of biological analyses and characterization.
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5.发明申请公开(公告)号：US20180015473A1
公开(公告)日：2018-01-18
申请号：US15717847
申请日：2017-09-27
Applicant: 10X Genomics, Inc.
Inventor： Rajiv Bharadwaj , Kevin Ness , Debkishore Mitra , Donald Masquelier , Anthony Makarewicz , Christopher Hindson , Benjamin Hindson , Serge Saxonov
CPC classification number: B01L3/502761 , B01L3/0241 , B01L3/502784 , B01L2200/0673 , B01L2300/0816 , B01L2400/049 , B01L2400/086 , G01N35/085 , G01N2035/00237 , G01N2035/1034
Abstract: The disclosure provides devices, systems and methods for the generation of encapsulated reagents and the partitioning of encapsulated reagents for use in subsequent analyses and/or processing, such as in the field of biological analyses and characterization.
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Patent Agency Ranking
公开(公告)号：US20190203262A1
公开(公告)日：2019-07-04
申请号：US16242962
申请日：2019-01-08
Applicant: 10X Genomics, Inc.
Inventor： Benjamin Hindson , Christopher Hindson , Michael Schnall-Levin , Kevin Ness , Mirna Jarosz , Donald Masquelier , Serge Saxonov , Landon Merrill , Andrew Price , Paul Hardenbol , Yuan Li
IPC: C12Q1/6806 , C12N15/10
CPC classification number: C12Q1/6806 , B01J2219/005 , B01J2219/00547 , B01J2219/00572 , B01J2219/00722 , C12N15/1006 , C12N15/1065 , C12Q2535/122 , C12Q2563/159
Abstract: This disclosure provides methods and compositions for sample processing, particularly for sequencing applications. Included within this disclosure are bead compositions, such as diverse libraries of beads attached to large numbers of oligonucleotides containing barcodes. Often, the beads provides herein are degradable. For example, they may contain disulfide bonds that are susceptible to reducing agents. The methods provided herein include methods of making libraries of barcoded beads as well as methods of combining the beads with a sample, such as by using a microfluidic device.
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公开(公告)号：US20170362587A1
公开(公告)日：2017-12-21
申请号：US15693374
申请日：2017-08-31
Applicant: 10X GENOMICS, INC.
Inventor： Benjamin Hindson , Serge Saxonov , Kevin Ness , Paul Hardenbol , Christopher Hindson , Donald Masquelier , Mirna Jarosz , Michael Schnall-Levin
IPC: C12N15/10 , C12Q1/68 , C12N15/11 , G01N33/543
CPC classification number: C12N15/1065 , C12N15/11 , C12Q1/6806 , C12Q1/6874 , C12Q1/6876 , C12Q2600/112 , G01N33/5436
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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8.发明申请FLUIDIC DEVICES, SYSTEMS, AND METHODS FOR ENCAPSULATING AND PARTITIONING REAGENTS, AND APPLICATIONS OF SAME 有权流体装置，系统和用于包封和分配试剂的方法及其应用公开(公告)号：US20150292988A1
公开(公告)日：2015-10-15
申请号：US14682952
申请日：2015-04-09
Applicant: 10X Genomics, Inc.
Inventor： Rajiv Bharadwaj , Kevin Ness , Debkishore Mitra , Donald Masquelier , Anthony Makarewicz , Christopher Hindson , Benjamin Hindson , Serge Saxonov
CPC classification number: B01L3/502761 , B01L3/0241 , B01L3/502784 , B01L2200/0673 , B01L2300/0816 , B01L2400/049 , B01L2400/086 , G01N35/085 , G01N2035/00237 , G01N2035/1034
Abstract: The disclosure provides devices, systems and methods for the generation of encapsulated reagents and the partitioning of encapsulated reagents for use in subsequent analyses and/or processing, such as in the field of biological analyses and characterization.
Abstract translation: 本公开提供了用于产生封装的试剂的装置，系统和方法以及用于后续分析和/或加工的包封试剂的分配，例如在生物分析和表征领域。
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公开(公告)号：US20240376519A1
公开(公告)日：2024-11-14
申请号：US18384527
申请日：2023-10-27
Applicant: 10X Genomics, Inc.
Inventor： Benjamin Hindson , Christopher Hindson , Michael Schnall-Levin , Kevin Ness , Mirna Jarosz , Donald Masquelier , Serge Saxonov , Landon Merrill , Andrew Price , Paul Hardenbol , Yuan Li
IPC: C12Q1/6806 , C12N15/10
Abstract: This disclosure provides methods and compositions for sample processing, particularly for sequencing applications. Included within this disclosure are bead compositions, such as diverse libraries of beads attached to large numbers of oligonucleotides containing barcodes. Often, the beads provides herein are degradable. For example, they may contain disulfide bonds that are susceptible to reducing agents. The methods provided herein include methods of making libraries of barcoded beads as well as methods of combining the beads with a sample, such as by using a microfluidic device.
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公开(公告)号：US11591637B2
公开(公告)日：2023-02-28
申请号：US16056231
申请日：2018-08-06
Applicant: 10X Genomics, Inc.
Inventor： Benjamin Hindson , Christopher Hindson , Michael Schnall-Levin , Kevin Ness , Mirna Jarosz , Donald Masquelier , Serge Saxonov , Landon Merrill , Andrew Price , Paul Hardenbol , Yuan Li
IPC: C12Q1/68 , C12N15/10 , C12Q1/6806
Abstract: This disclosure provides methods and compositions for sample processing, particularly for sequencing applications. Included within this disclosure are bead compositions, such as diverse libraries of beads attached to large numbers of oligonucleotides containing barcodes. Often, the beads provides herein are degradable. For example, they may contain disulfide bonds that are susceptible to reducing agents. The methods provided herein include methods of making libraries of barcoded beads as well as methods of combining the beads with a sample, such as by using a microfluidic device.
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