公开(公告)号：US08273071B2

公开(公告)日：2012-09-25

申请号：US12587222

申请日：2009-10-01

申请人： Leroy E. Hood ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Robert Langer ,  Clarence T. Tegreene ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Leroy E. Hood ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Robert Langer ,  Clarence T. Tegreene ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： A61M31/00

CPC分类号： A61M5/14276 ,  A61M2005/14513 ,  A61M2205/0244 ,  A61M2205/3523 ,  A61M2205/3569 ,  G05D7/0623 ,  G05D23/1917

摘要： Embodiments of a system including a remotely controlled substance delivery device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, a delivery device or related device may be placed in an environment in order to pump a material into the environment or into an additional fluid handling structure within the device. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. The concentration of a substance in the fluid to be delivered may be modified by a remote control signal. In selected embodiments, a magnetic field, an electric field, or electromagnetic control signal may be used.

摘要翻译： 描述了包括远程控制物质输送装置和相关控制器的系统的实施例。 还公开了装置的使用和控制方法。 根据一些实施例，输送装置或相关装置可以放置在环境中，以便将材料泵入环境或装置内的附加流体处理结构。 示例性环境包括生物体，水体或封闭体积的流体。 被输送流体中物质的浓度可以通过遥控信号来改变。 在所选择的实施例中，可以使用磁场，电场或电磁控制信号。

公开(公告)号：US08198080B2

公开(公告)日：2012-06-12

申请号：US11304486

申请日：2005-12-14

申请人： Ed Harlow ,  Edward K. Y. Jung ,  Robert Langer ,  Eric C. Leuthardt ,  Lowell L. Wood, Jr.

发明人： Ed Harlow ,  Edward K. Y. Jung ,  Robert Langer ,  Eric C. Leuthardt ,  Lowell L. Wood, Jr.

IPC分类号： C12N5/00 ,  C12N5/02

CPC分类号： A61F2/00 ,  A61K9/0024 ,  A61K47/6901 ,  A61K2035/126 ,  A61L27/3608 ,  A61L27/3808 ,  B33Y80/00 ,  C12N5/0654 ,  C12N2510/00

摘要： Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to subjects.

公开(公告)号：US08172833B2

公开(公告)日：2012-05-08

申请号：US12589847

申请日：2009-10-28

申请人： Leroy E. Hood ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Robert Langer ,  Clarence T. Tegreene ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Leroy E. Hood ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Robert Langer ,  Clarence T. Tegreene ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： A61K9/22

CPC分类号： A61K9/0009 ,  A61M5/14276 ,  A61M5/145 ,  A61M5/172 ,  A61M5/1723 ,  A61M31/002 ,  A61M2005/14513 ,  A61M2205/0266 ,  A61M2205/0288 ,  A61M2205/3523 ,  A61M2205/3569 ,  A61M2205/36

摘要： Embodiments of a system including a remotely controlled substance delivery device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, a delivery device or related device may be placed in an environment in order to pump a material into the environment or into an additional fluid handling structure within the device. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. The concentration of a substance in the fluid to be delivered may be modified by a remote control signal. In selected embodiments, a magnetic field, an electric field, or electromagnetic control signal may be used.

公开(公告)号：US08109923B2

公开(公告)日：2012-02-07

申请号：US11505259

申请日：2006-08-15

申请人： Leroy E. Hood ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Robert Langer ,  Clarence T. Tegreene ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Leroy E. Hood ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Robert Langer ,  Clarence T. Tegreene ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： A61K9/22

CPC分类号： A61K9/0004 ,  A61K9/0009 ,  A61K9/0024 ,  A61M5/14276 ,  A61M5/145 ,  A61M5/172 ,  A61M5/1723 ,  A61M2005/14513 ,  A61M2205/0266 ,  A61M2205/0288 ,  A61M2205/3523 ,  A61M2205/3569 ,  A61M2205/36 ,  A61N1/08

摘要： Embodiments of a system including a remotely controlled osmotic pump device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, an osmotic pump device is placed in an environment in order to pump a material into the environment or into an additional fluid handling structure within the osmotic pump device. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. In selected embodiments, a magnetic field, an electric field, or electromagnetic control signal may be used.

摘要翻译： 描述了包括远程控制的渗透泵装置和相关控制器的系统的实施例。 还公开了装置的使用和控制方法。 根据一些实施例，将渗透泵装置放置在环境中以便将材料泵送到渗透泵装置内的环境或另外的流体处理结构中。 示例性环境包括生物体，水体或封闭体积的流体。 在所选择的实施例中，可以使用磁场，电场或电磁控制信号。

公开(公告)号：US20110280922A1

公开(公告)日：2011-11-17

申请号：US13063887

申请日：2009-11-09

申请人： Eyal S. Ron ,  William F. Crowley ,  Robert Langer ,  Surajit K. Biswas ,  Quentin Baca ,  Armen Tashjian ,  Preston H. Saunders

发明人： Eyal S. Ron ,  William F. Crowley ,  Robert Langer ,  Surajit K. Biswas ,  Quentin Baca ,  Armen Tashjian ,  Preston H. Saunders

IPC分类号： A61F13/20 ,  A61K38/02 ,  A61P31/12 ,  A61K47/32 ,  A61K47/34 ,  A61M31/00 ,  A61K31/56 ,  A61K38/09

CPC分类号： A61K47/32 ,  A61F13/20 ,  A61K9/0036 ,  A61K9/0092 ,  A61K38/09 ,  A61M31/002

摘要： The invention relates to a therapeutic device for the delivery of therapeutic agents, e.g. a peptide such as leuprolide, via the vagina to a female mammal. In some embodiments, the invention also relates to methods for the treatment of obesity and eating disorders, diabetes, multiple sclerosis (MS), endometriosis, uterine fibroids, polycystic ovarian disease, various cancers such as breast cancer, acne, hirsutism, microbial or fungal or viral infections such as bacterial vaginosis or AIDS/HIV, and chronic diseases using a disclosed vaginal device.

摘要翻译： 本发明涉及用于递送治疗剂的治疗装置，例如， 一种肽，如亮丙瑞林，通过阴道到雌性哺乳动物。 在一些实施方案中，本发明还涉及治疗肥胖症和进食障碍，糖尿病，多发性硬化（MS），子宫内膜异位症，子宫肌瘤，多囊卵巢疾病，各种癌症如乳腺癌，痤疮，多毛症，微生物或真菌的方法 或病毒感染如细菌性阴道炎或AIDS / HIV，以及使用公开的阴道装置的慢性疾病。

公开(公告)号：US08053220B2

公开(公告)日：2011-11-08

申请号：US11451986

申请日：2006-06-12

申请人： Ed Harlow ,  Roderick A. Hyde ,  Edward K. Y. Jung ,  Robert Langer ,  Eric C. Leuthardt ,  Lowell L. Wood, Jr.

发明人： Ed Harlow ,  Roderick A. Hyde ,  Edward K. Y. Jung ,  Robert Langer ,  Eric C. Leuthardt ,  Lowell L. Wood, Jr.

IPC分类号： C12N11/00 ,  C12N1/00

CPC分类号： C12N5/0691 ,  A61K9/0024 ,  A61K35/44 ,  A61K47/6901 ,  A61K2035/126 ,  A61L27/18 ,  A61L27/3608 ,  A61L27/3612 ,  A61L27/3808 ,  A61L27/3813 ,  A61L27/54 ,  A61L2300/64 ,  B33Y80/00 ,  C12N5/0618 ,  C12N5/0654 ,  C12N2502/13 ,  C12N2502/1305 ,  C12N2502/1311 ,  C12N2502/1317 ,  C12N2502/1323 ,  C12N2502/1329 ,  C12N2502/1335 ,  C12N2502/1341 ,  C12N2502/1347 ,  C12N2502/1352 ,  C12N2502/1358 ,  C12N2502/1364 ,  C12N2502/137 ,  C12N2502/1376 ,  C12N2502/1382 ,  C12N2502/1388 ,  C12N2502/1394 ,  C12N2510/00

摘要： Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to subjects.

摘要翻译： 公开了骨笼，包括用于生物相容性植入的装置。 骨的结构可用于向受试者提供活细胞和组织以及生物活性分子。

公开(公告)号：US20110192343A1

公开(公告)日：2011-08-11

申请号：US12672797

申请日：2008-09-23

申请人： Hocine Abir ,  Robert Langer

发明人： Hocine Abir ,  Robert Langer

IPC分类号： C30B23/02 ,  B05D3/12

CPC分类号： H01L21/76254 ,  H01L23/36 ,  H01L2924/0002 ,  H01L2924/00

摘要： A method for manufacturing an electronic, optic, optoelectronic or photovoltaic structure of a substrate having a thin layer on one face thereof, by forming an embrittled substrate having first and second faces and an embrittlement zone therebetween, the embrittlement zone defining the substrate and a remainder; depositing a thin layer of material on both the first and second faces of the embrittled substrate; and cleaving the embrittled substrate at the embrittlement zone to obtain the structure having the thin layer of deposited material on one face and one face that is exposed.

摘要翻译： 一种制造基片的电子，光学，光电或光电结构的方法，该基片在其一面上具有薄层，通过形成具有第一和第二面的脆化基底和其间的脆化区，限定基底的脆化区和剩余部分 ; 在脆化的衬底的第一和第二表面上沉积薄层材料; 并在脆化区裂开脆化的基材，得到在一个面上具有沉积材料的薄层的结构和暴露的一个面。

公开(公告)号：US07989196B2

公开(公告)日：2011-08-02

申请号：US12661633

申请日：2010-03-18

申请人： Heather L. Callahan ,  W. Daniel Hillis ,  Roderick A. Hyde ,  Edward K. Y. Jung ,  Robert Langer ,  Nathan P. Myhrvold ,  Lowell L. Wood, Jr.

发明人： Heather L. Callahan ,  W. Daniel Hillis ,  Roderick A. Hyde ,  Edward K. Y. Jung ,  Robert Langer ,  Nathan P. Myhrvold ,  Lowell L. Wood, Jr.

IPC分类号： C12M1/00 ,  C12Q1/68 ,  C12M3/00

CPC分类号： G06F19/18

摘要： Systems, methods, compositions and apparatus relating to genome selection are disclosed.

公开(公告)号：US20110150296A1

公开(公告)日：2011-06-23

申请号：US12655184

申请日：2009-12-23

申请人： Philip A. Eckhoff ,  William Gates ,  Peter L. Hagelstein ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Jordin T. Kare ,  Robert Langer ,  Eric C. Leuthardt ,  Erez Lieberman ,  Nathan P. Myhrvold ,  Michael Schnall-Levin ,  Clarence T. Tegreene ,  Lowell L. Wood, JR.

发明人： Philip A. Eckhoff ,  William Gates ,  Peter L. Hagelstein ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Jordin T. Kare ,  Robert Langer ,  Eric C. Leuthardt ,  Erez Lieberman ,  Nathan P. Myhrvold ,  Michael Schnall-Levin ,  Clarence T. Tegreene ,  Lowell L. Wood, JR.

IPC分类号： G06K9/62

CPC分类号： G06Q30/02

摘要： A method may include automatically remotely identifying at least one characteristic of an individual via facial recognition; and providing a display for the individual, the display having a content at least partially based on the identified at least one characteristic of the individual. A system may include a facial recognition module configured for automatically remotely identifying at least one characteristic of an individual via facial recognition; and a display module coupled with the facial recognition module, the display module configured for providing a display for the individual, the display having a content at least partially based on the identified at least one characteristic of the individual.

公开(公告)号：US07947455B2

公开(公告)日：2011-05-24

申请号：US12661548

申请日：2010-03-18

申请人： Heather L. Callahan ,  W. Daniel Hillis ,  Roderick A. Hyde ,  Edward K. Y. Jung ,  Robert Langer ,  Nathan P. Myhrvold ,  Lowell L. Wood, Jr.

发明人： Heather L. Callahan ,  W. Daniel Hillis ,  Roderick A. Hyde ,  Edward K. Y. Jung ,  Robert Langer ,  Nathan P. Myhrvold ,  Lowell L. Wood, Jr.

IPC分类号： C12Q1/68

CPC分类号： G06F19/18 ,  C12Q1/6874

摘要： Systems, methods, compositions and apparatus relating to genome selection are disclosed.

摘要翻译： 公开了与基因组选择相关的系统，方法，组合物和设备。