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公开(公告)号:US20060142306A1
公开(公告)日:2006-06-29
申请号:US10532110
申请日:2003-02-19
申请人: Michael Johnson
发明人: Michael Johnson
IPC分类号: A61K31/4965 , C07D405/02
CPC分类号: C07D241/28 , A61K31/4965 , A61K31/497 , A61K31/706 , A61K45/06 , C07D241/26 , C07D241/32 , C07D405/12 , C07H15/26
摘要: The present invention relates to sodium channel blockers. The present invention also includes a variety of methods of treatment using these inventive sodium channel blockers.
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公开(公告)号:US20060116388A1
公开(公告)日:2006-06-01
申请号:US11332054
申请日:2006-01-13
申请人: Julio Medina , Michael Johnson , An-Rong Li , Jiwen Liu , Alan Huang
发明人: Julio Medina , Michael Johnson , An-Rong Li , Jiwen Liu , Alan Huang
IPC分类号: A61K31/519 , A61K31/517 , C07D487/02 , C07D403/02
CPC分类号: C07D401/04 , C07D213/40 , C07D235/14 , C07D239/91 , C07D249/12 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/12 , C07D405/04 , C07D413/14 , C07D417/04 , C07D471/04 , C07D475/04
摘要: Compounds, compositions and methods that are useful in the treatment of inflammatory and immune conditions and diseases are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of a chemokine receptor. The subject methods are useful for the treatment of inflammatory and immunoregulatory disorders and diseases, such as multiple sclerosis, rheumatoid arthritis and type I diabetes.
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公开(公告)号:US20060102135A1
公开(公告)日:2006-05-18
申请号:US10989802
申请日:2004-11-17
申请人: Michael Johnson
发明人: Michael Johnson
IPC分类号: F02B75/32
摘要: An internal combustion engine that replaces the throw journal of a crankshaft with a contour that is dynamic rather than static. The contour is such that three cycles of engine operation is not affected, i.e. exhaust, intake, and compression. The contour deviates only during the power stroke where an increased incidence to the circular for approximately ninety degrees of rotation is incorporated. This defers from previous attempts by eliminating complex geometries such as epitrochoidal, sinusoidal, or the elliptical that by their nature negatively affect the exhaust, intake, and compression strokes of the Otto cycle when compared to the traditional crankshaft. Additionally, the deviation from the circular orbit during the power cycle optimizes to a larger extent the leverage available for peak thermodynamic pressures in the cylinder in the brief optimum time afforded by that pressure. Compressors so configured would also be more efficient by reducing the energy requirements of an input shaft.
摘要翻译: 一种内燃机,其以具有动态而不是静止的轮廓替代曲轴的投掷轴颈。 轮廓使得发动机操作的三个循环不受影响,即排气,进气和压缩。 轮廓仅在功率冲程期间偏离,其中引入了大约90度旋转的对圆形的增加的入射。 通过消除复杂的几何形状(例如外旋,正弦曲线或椭圆形),与传统曲轴相比,它们本身会对Otto循环的排气,进气和压缩冲程产生负面影响,从而阻止了以前的尝试。 此外,在动力循环期间,与循环轨道的偏离在较大程度上优化了在该压力提供的最短时间内可用于气缸顶部热力学压力的杠杆作用。 如此配置的压缩机也将通过减少输入轴的能量需求而更有效。
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公开(公告)号:US07039717B2
公开(公告)日:2006-05-02
申请号:US09965952
申请日:2001-09-27
申请人: Michael Johnson
发明人: Michael Johnson
IPC分类号: G06F13/00
CPC分类号: H04L69/16 , H04L29/06 , H04L69/08 , H04L69/161 , H04L69/162 , H04L69/169
摘要: An Internet client communicates with an Internet server such as an HTTP server or SMTP server through a TCP streaming socket on the Internet device with the Internet client. The TCP streaming sockets can be established through an Internet ready command line interface. The Internet ready command line interface includes “IR” commands that can establish, resume, release and terminate TCP sockets.
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105.
公开(公告)号:US20060040954A1
公开(公告)日:2006-02-23
申请号:US10920391
申请日:2004-08-18
申请人: Michael Johnson
发明人: Michael Johnson
IPC分类号: A61K31/4965 , C07D405/02
CPC分类号: C07D241/26
摘要: The present invention relates to sodium channel blockers. The present invention also includes a variety of methods of treatment using these inventive sodium channel blockers.
摘要翻译: 本发明涉及钠通道阻断剂。 本发明还包括使用这些本发明的钠通道阻断剂的各种治疗方法。
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公开(公告)号:US20050203665A1
公开(公告)日:2005-09-15
申请号:US11127341
申请日:2005-05-12
申请人: Rajan Penkar , Michael Johnson , Larry Hanlon , Raymond Reulbach , Gina Jones , Tony Castagno
发明人: Rajan Penkar , Michael Johnson , Larry Hanlon , Raymond Reulbach , Gina Jones , Tony Castagno
CPC分类号: G06Q10/08 , G06Q10/087
摘要: A computer system for use in reducing overall pipeline inventory within a distribution network that includes a central warehouse that is: (1) adjacent a transportation hub; and (2) configured to store sufficient component parts to provide a regular stream of parts to each of a plurality of manufacturing facilities. The computer system is preferably configured for coordinating the transportation of a regular stream of parts to each of the manufacturing facilities by transporting component parts from the central warehouse to the manufacturing facilities primarily via an expedited delivery service performed using the transportation hub. The expedited delivery service may include, for example, guaranteed delivery within one or two days. This reduces the overall pipeline and warehouse inventory within the distribution network by reducing the average transit time for each part, and by reducing the amount of safety stock that is needed to support the operations of the manufacturing facilities.
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公开(公告)号:US20050195810A1
公开(公告)日:2005-09-08
申请号:US10793392
申请日:2004-03-04
申请人: Danny Sung , Wade Mergenthal , Simon Wong , Michael Johnson
发明人: Danny Sung , Wade Mergenthal , Simon Wong , Michael Johnson
摘要: The invention includes network mesh routers and methods for network mesh routing that are capable of transparently routing data packets to other clients on the network. The invention uses the link layer (L2) for route initiation and active client discovery and a combination L2 and the network layer (L3) for passive client discovery. By responding to packets on L2, networks composed of transparent mesh routers require neither configuration by the network operator nor any pre-configuration of the network clients.
摘要翻译: 本发明包括网络路由器和网络路由的方法,其能够将数据分组透明地路由到网络上的其他客户端。 本发明使用链路层(L2)用于路由发起和主动客户端发现,组合L2和网络层(L3)用于被动客户端发现。 通过响应L2上的数据包,由透明网状路由器组成的网络既不需要网络运营商的配置,也不需要网络客户端的任何预配置。
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公开(公告)号:US20050141150A1
公开(公告)日:2005-06-30
申请号:US10975500
申请日:2004-10-29
申请人: Philip Bentley , James Fox , Alan Hudd , Martyn Robinson , Michael Johnson , Ian Williamson
发明人: Philip Bentley , James Fox , Alan Hudd , Martyn Robinson , Michael Johnson , Ian Williamson
CPC分类号: H01L23/5389 , C23C18/1608 , C23C18/1621 , C23C18/208 , H01L24/24 , H01L24/82 , H01L2224/05553 , H01L2224/24051 , H01L2224/24226 , H01L2224/24998 , H01L2224/45124 , H01L2224/76155 , H01L2224/82007 , H01L2224/82102 , H01L2924/00014 , H01L2924/01006 , H01L2924/01013 , H01L2924/01029 , H01L2924/01033 , H01L2924/01046 , H01L2924/01047 , H01L2924/01074 , H01L2924/01078 , H01L2924/01079 , H01L2924/01082 , H01L2924/014 , H01L2924/12041 , H01L2924/12042 , H01L2924/12043 , H01L2924/12044 , H01L2924/19041 , H01L2924/19042 , H01L2924/19043 , H05K3/182 , H05K3/32 , H05K2201/10477 , H05K2203/013 , H05K2203/0709 , H05K2203/1469 , Y10T29/49117 , Y10T29/4913 , Y10T29/49131 , Y10T29/49144 , H01L2924/00 , H01L2224/48
摘要: A contact of a component is electrically connected to an associated contact of an electrical circuit, typically formed on a substrate, by depositing material between the contacts, the material forming or being processed to form an electrical connection between the contacts. The invention also provides apparatus for this purpose and a resulting circuit.
摘要翻译: 组件的触点通常在触点之间沉积材料,形成或被处理以在触点之间形成电连接的材料,电连接到通常形成在基板上的电路的相关触头。 本发明还提供了用于该目的的装置以及所产生的电路。
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109.
公开(公告)号:US20050138180A1
公开(公告)日:2005-06-23
申请号:US10742358
申请日:2003-12-19
申请人: John Minami , Michael Johnson , Robin Uyeshiro
发明人: John Minami , Michael Johnson , Robin Uyeshiro
CPC分类号: H04L29/06 , H04L49/90 , H04L63/1458 , H04L69/16 , H04L69/163
摘要: A system and method are provided for establishing network connections. Initially, an attempt to establish a connection on a network is identified. A portion of memory is then allocated for storing data associated with the connection.
摘要翻译: 提供了一种用于建立网络连接的系统和方法。 首先,确定在网络上建立连接的尝试。 然后分配存储器的一部分用于存储与该连接相关联的数据。
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公开(公告)号:US20050126826A1
公开(公告)日:2005-06-16
申请号:US10735323
申请日:2003-12-12
申请人: Keith Moriarty , Michael Johnson
发明人: Keith Moriarty , Michael Johnson
摘要: A directional casing drilling system includes a casing string, a mud motor operatively coupled to the casing string, a rotary steerable system operatively coupled to the mud motor, and a drill bit operatively coupled to the rotary steerable system.
摘要翻译: 定向套管钻井系统包括套管柱,可操作地联接到套管柱的泥浆马达,可操作地联接到泥浆马达的旋转可操纵系统以及可操作地联接到旋转导向系统的钻头。
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