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公开(公告)号：US20160166258A1
公开(公告)日：2016-06-16
申请号：US14990676
申请日：2016-01-07
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Terrance Tran
CPC classification number: A61B17/1219 , A61B17/12113 , A61B17/1214 , A61B17/12145 , A61B17/12154 , A61B17/12168 , A61L31/00 , A61L31/022 , A61L31/041 , A61L31/048 , A61L31/06 , A61L31/14 , A61L31/145 , A61L31/146 , A61L2400/04 , C08L71/02
Abstract: Devices for the occlusion of body cavities, such as the embolization of vascular aneurysms and the like, and methods for making and using such devices. The devices may be comprised of novel expansile materials, novel infrastructure design, or both. The devices provided are very flexible and enable deployment with reduced or no damage to bodily tissues, conduits, cavities, etceteras.
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Patent Agency Ranking
公开(公告)号：US20150306227A1
公开(公告)日：2015-10-29
申请号：US14678514
申请日：2015-04-03
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Clayton G. Harris , Michael J. Constant
IPC: A61K47/32 , A61K9/70 , C07F15/00 , A61K47/48 , A61K47/02 , C07H19/06 , A61K31/7068 , A61K31/787
CPC classification number: A61K47/32 , A61K9/0092 , A61K31/7068 , A61K31/787 , A61K47/58 , A61K49/04 , A61L31/145 , A61L31/148 , A61L31/16 , A61L31/18 , A61L2430/36 , C07F15/0093 , C07H19/06
Abstract: Polymers are described herein comprising: a reaction product of a prepolymer solution including at least one macromer and at least one visualization agent; and an active agent electrostatically bound to the polymer filament or chemically bound to the at least one monomer; wherein the polymer filament does not include metallic support members.
Abstract translation: 本文描述了聚合物，其包含：包含至少一种大分子单体和至少一种可视化试剂的预聚物溶液的反应产物; 和与所述聚合物长丝静电结合或化学结合至所述至少一种单体的活性剂; 其中聚合物长丝不包括金属支撑构件。
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公开(公告)号：US09078950B2
公开(公告)日：2015-07-14
申请号：US14054515
申请日：2013-10-15
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Edward Michael Keeley , Rob Greene , Clayton Harris
CPC classification number: A61L24/06 , A61K49/0442 , A61K49/12 , A61L24/001 , A61L24/0015 , A61L2300/44 , A61L2400/06 , A61L2430/36 , C08L33/08 , C08L33/26
Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological pH solution; wherein the biocompatible polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
Abstract translation: 描述了包含生物相容性聚合物的聚合物组合物，其包括与可视化试剂和非生理pH溶液的生物可降解连接; 其中所述生物相容性聚合物可溶于非生理pH溶液中，并且在生理pH下不溶。 公开了形成溶液和聚合物的方法以及治疗用途的方法。
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公开(公告)号：US09011884B2
公开(公告)日：2015-04-21
申请号：US13865068
申请日：2013-04-17
Applicant: MicroVention, Inc.
Inventor： Michael Constant , Edward Michael Keeley , Joshua Garretson , Gregory M. Cruise
CPC classification number: A61L31/048 , A61K9/0019 , A61K9/0024 , A61K47/30 , A61K47/34 , A61K49/0404 , A61K49/126 , A61K51/1213 , A61L31/145 , A61L31/18 , A61L2430/36 , Y10T428/298 , C08L33/26
Abstract: Described herein are apparatus, compositions, systems and methods for occluding vascular structures and vascular malformations with radiopaque hydrogel filaments. The filaments can contain no support members and can be CT and MR compatible. Methods of forming such filaments are also disclosed.
Abstract translation: 本文描述的是用不透射线水凝胶细丝阻塞血管结构和血管畸形的装置，组合物，系统和方法。 长丝不能含有支撑构件，可以兼容CT和MR。 还公开了形成这种细丝的方法。
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公开(公告)号：US20130336917A1
公开(公告)日：2013-12-19
申请号：US13917323
申请日：2013-06-13
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Joshua Garretson
IPC: A61K31/785
CPC classification number: A61K31/785 , A61K9/0024 , A61K31/78 , A61K47/32 , A61L24/0089 , A61L24/046 , A61L2430/36
Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
Abstract translation: 描述包含聚合物的组合物; 非生理pH溶液; 和可视化代理; 其中所述聚合物可溶于所述非生理pH溶液并且在生理pH下不溶。 公开了形成溶液和聚合物的方法以及治疗用途的方法。
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公开(公告)号：US20130302251A1
公开(公告)日：2013-11-14
申请号：US13865068
申请日：2013-04-17
Applicant: MicroVention, Inc.
Inventor： Michael Constant , Edward Michael Keeley , Joshua Garretson , Gregory M. Cruise
CPC classification number: A61L31/048 , A61K9/0019 , A61K9/0024 , A61K47/30 , A61K47/34 , A61K49/0404 , A61K49/126 , A61K51/1213 , A61L31/145 , A61L31/18 , A61L2430/36 , Y10T428/298 , C08L33/26
Abstract: Described herein are apparatus, compositions, systems and methods for occluding vascular structures and vascular malformations with radiopaque hydrogel filaments. The filaments can contain no support members and can be CT and MR compatible. Methods of forming such filaments are also disclosed.
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