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公开(公告)号：US10941179B2
公开(公告)日：2021-03-09
申请号：US16184028
申请日：2018-11-08
Inventor： Yukako Senga , Hideki Watanabe , Shinya Honda
IPC: C07K1/22 , C07K16/00 , C07K1/14 , C07K1/02 , C07K14/00 , C07K7/06 , C07K7/08 , C07K1/32 , C07K16/06 , C07K1/36 , A61K39/395
Abstract: The present invention relates to a method for suppressing aggregation of polypeptide. Specifically, the present invention relates to a method for suppressing, in a solution comprising an antibody or an Fc region-containing protein, formation of an aggregate derived from an antibody or an Fc region-containing protein having a non-native conformation, the method comprising: the steps of (i) binding an AF.2A1 polypeptide or an analog thereof with an aggregate derived from the antibody or Fc region-containing protein having a non-native conformation in the solution; and (ii) collecting the aggregate bound to the polypeptide or analog thereof from the solution.
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公开(公告)号：US10939851B2
公开(公告)日：2021-03-09
申请号：US15551102
申请日：2016-02-10
Inventor： Toru Yamada , Shinji Umeyama
IPC: A61B5/1455 , A61B10/00 , A61B5/00
Abstract: Provided is a multi-channel brain-functional near infrared spectroscopy device capable of easily levelling detector noise. The following control is performed: setting transmittances of all of optical attenuators to 1, setting intensities of all of light sources to a maximum light intensity within a safe irradiation range; determining the effective illumination intensity of each light source probe i as well as a minimum effective illumination intensity and a maximum effective illumination intensity thereof; changing the transmittance ai of each optical attenuator i on the light source probe side to [the minimum effective illumination intensity/effective illumination intensity of each light source probe i], thereby levelling the effective illumination intensity; and increasing the intensities of all of the light sources by W=[the maximum effective illumination intensity/the minimum effective incident efficiency] times, and determining the effective detection rate of each detector probe j as well as the minimum effective detection rate thereof; and performing control so as to level the effective detection rate by changing the transmittance aj of each optical attenuator j on the detector probe side to [the minimum effective detection rate/effective detection rate of each detector probe j], thereby equalizing detector noise among all the channels k.
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公开(公告)号：US10936072B2
公开(公告)日：2021-03-02
申请号：US16511760
申请日：2019-07-15
Inventor： Norio Nakamura , Yukio Fukui , Masataka Sakai , Natsuo Koda , Koji Osaki
Abstract: A haptic information presentation system uses a human sensory characteristic or illusion to suitably control a physical quantity, and causes a person to feel a force which cannot exist physically, or a haptic sensory physical characteristic.
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公开(公告)号：US20210036217A1
公开(公告)日：2021-02-04
申请号：US16498936
申请日：2018-02-15
Applicant: National Institute of Advanced Industrial Science and Technology , TOHOKU UNIVERSITY , NATIONAL INSTITUTE FOR MATERIALS SCIENCE
Inventor： Takayuki NOZAKI , Shinji YUASA , Rachwal Anna KOZIOL , Masahito TSUJIKAWA , Masafumi SHIRAI , Kazuhiro HONO , Tadakatsu OHKUBO , Xiandong XU
Abstract: According to one embodiment, a magnetic element includes a first layer and a second layer. The first layer includes a first element and a second element. The first element includes at least one selected from the group consisting of Fe, Co, and Ni. The second element includes at least one selected from the group consisting of Ir and Os. The second layer is nonmagnetic.
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公开(公告)号：US10906869B2
公开(公告)日：2021-02-02
申请号：US15563323
申请日：2016-03-31
Inventor： Hiroshi Senoh , Toshikatsu Kojima , Nobuhiko Takeichi , Hisanori Ando
IPC: H01M10/052 , H01M10/054 , C07C381/00 , H01M4/62 , H01M4/38 , C01B32/75 , H01M4/58 , H01M4/60 , H01M10/0562 , C01B32/70 , C08L71/02 , G01N21/65 , H01M10/0525
Abstract: An organic sulfur material comprising carbon, hydrogen, oxygen, and sulfur as constituent elements, and having peaks in the vicinity of 482 cm−1, 846 cm−1, 1066 cm−1, 1279 cm−1, and 1442 cm−1 in a Raman spectrum detected by Raman spectroscopy, the peak in the vicinity of 1442 cm−1 being most intense, has a high capacity and high heat resistance, although a liquid organic starting material is used.
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Patent Agency Ranking
公开(公告)号：US10862120B2
公开(公告)日：2020-12-08
申请号：US15780472
申请日：2016-12-07
Inventor： Titus Nyamwaro Masese , Masahiro Shikano , Hikari Sakaebe , Hiroshi Senoh , Hikaru Sano
IPC: H01B1/08 , H01M4/00 , H01M4/525 , H01M4/131 , H01M4/505 , H01M10/054 , C01G49/00 , H01M4/485 , C01G3/00 , C01G45/12 , H01M4/62 , H01M4/02
Abstract: By using a potassium ion secondary battery positive electrode active material comprising a potassium compound represented by general formula (1): KnMOm, wherein M is copper or iron, n is 0.5 to 3.5, and m is 1.5 to 2.5, provided is a potassium ion secondary battery positive electrode active material having higher theoretical discharge capacity and higher effective capacity than a potassium secondary battery using Prussian blue as a positive electrode active material.
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公开(公告)号：US20200377728A1
公开(公告)日：2020-12-03
申请号：US16863526
申请日：2020-04-30
Applicant: National Institute of Advanced Industrial Science and Technology , Fuji Polymer Industries Co., Ltd.
Inventor： Yuichi TOMINAGA , Yoshiki SUGIMOTO , Yusuke IMAI , Yuji HOTTA , Setsuo KIKUCHI , Makoto IWAI , Takumi KATAISHI
IPC: C08L83/04
Abstract: Composite resin granules 5 contain a binder resin 2 and a thermally conductive filler. The thermally conductive filler includes a non-anisotropic thermally conductive filler 3 and an anisotropic thermally conductive filler 4. The composite resin granules containing the binder resin and the thermally conductive filler are formed into a spherical shape. The particles of the anisotropic thermally conductive filler 4 are oriented in random directions. A thermally conductive rein molded body 6 of the present invention is obtained by compressing the composite resin granules 5. Thus, the present invention provides the thermally conductive resin molded body that has relatively high thermal conductivities in the in-plane direction and the thickness direction, well-balanced directional properties of thermal conduction, and a low specific gravity, the composite resin granules suitable for the thermally conductive resin molded body, and methods for producing them.
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公开(公告)号：US10830951B2
公开(公告)日：2020-11-10
申请号：US16343998
申请日：2017-10-16
Applicant: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY , PHOTONICS ELECTRONICS TECHNOLOGY RESEARCH ASSOCIATION
Inventor： Akihiro Noriki , Takeru Amano
Abstract: An optical circuit includes a substrate, a waveguide, and a mirror. The substrate includes a first surface. The waveguide includes a first core. The first core is formed of a semiconductor material. The waveguide is over a first surface of the substrate. The mirror reflects light emitted from the waveguide in a direction away from the first surface of the substrate. The mirror is a concave mirror. The waveguide includes a region that functions as an SSC.
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公开(公告)号：US20200348238A1
公开(公告)日：2020-11-05
申请号：US16760019
申请日：2018-09-14
Inventor： Nao Terasaki , Kazuya Kikunaga
Abstract: [Object] An electric conductivity-measuring material which emits light according to electric conductivity of a measurement object; an electric conductivity-measuring film containing the material; and an electric conductivity-measuring device and an electric conductivity-measuring method using the electric conductivity-measuring film are provided. An electric resistivity-measuring material which emits light according to electric resistivity of a measurement object when electrons are made incident; an electric resistivity-measuring film containing the material; and an electric resistivity-measuring device and an electric resistivity-measuring method using the electric resistivity-measuring film are also provided.[Solution] An electric conductivity-measuring material is used, which contains at least one of a fluorescent substance, a luminescent substance, an electroluminescent substance, a fractoluminescent substance, a photochromic substance, an afterglow substance, a photostimulated luminescent substance and a mechanoluminescent substance.
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公开(公告)号：US10807878B2
公开(公告)日：2020-10-20
申请号：US15753904
申请日：2016-08-19
Inventor： Junji Akimoto , Naoki Hamao , Kunimitsu Kataoka
Abstract: Provided is a complex oxide that has a space group I-43d, has a high hydrogen content, contains almost no impurity phase, exhibits almost no aluminum substitution in the structure thereof, and is suitable for proton conductivity. This complex oxide is represented by a chemical formula Li7-x-yHxLa3Zr2-yMyO12 (M represents Ta and/or Nb, 3.2
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