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公开(公告)号：US10480029B2
公开(公告)日：2019-11-19
申请号：US15933299
申请日：2018-03-22
Applicant: 10X GENOMICS, INC.
Inventor： Zachary Bent , Josephine Harada , Christopher Hindson , Elliott Meer , Tarjei Sigurd Mikkelsen , Christopher Joachim O'Keeffe , Katherine Pfeiffer , Andrew D. Price , Paul Ryvkin , Serge Saxonov , John R. Stuelpnagel , Jessica Michele Terry , Solongo Batjargal Ziraldo
IPC: C12Q1/68 , C12Q1/6874 , C12Q1/683 , C12Q1/6806
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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公开(公告)号：US20190338353A1
公开(公告)日：2019-11-07
申请号：US16426762
申请日：2019-05-30
Applicant: 10X GENOMICS, INC.
Inventor： Phillip Belgrader , Zachary Bent , Rajiv Bharadwaj , Vijay Kumar Sreenivasa Gopalan , Josephine Harada , Christopher Hindson , Mohammad Rahimi Lenji , Michael Ybarra Lucero , Geoffrey McDermott , Elliott Meer , Tarjei Sigurd Mikkelsen , Christopher Joachim O'Keeffe , Katherine Pfeiffer , Andrew D. Price , Paul Ryvkin , Serge Saxonov , John R. Stuelpnagel , Jessica Michele Terry , Tobias Daniel Wheeler , Indira Wu , Solongo Batjargal Ziraldo
IPC: C12Q1/6874 , C12N15/10 , C12Q1/683 , C12Q1/6806 , C12Q1/6804
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing and analyte characterization. Such polynucleotide processing may be useful for a variety of applications, including analyte characterization by polynucleotide sequencing. The compositions, methods, systems, and devices disclosed herein generally describe barcoded oligonucleotides, which can be bound to a bead, such as a gel bead, useful for characterizing one or more analytes including, for example, protein (e.g., cell surface or intracellular proteins), genomic DNA, and RNA (e.g., mRNA or CRISPR guide RNAs). Also described herein, are barcoded labelling agents and oligonucleotide molecules useful for “tagging” analytes for characterization.
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123.发明授权公开(公告)号：US10343166B2
公开(公告)日：2019-07-09
申请号：US15596754
申请日：2017-05-16
Applicant: 10X Genomics, Inc.
Inventor： Rajiv Bharadwaj , Kevin Ness , Debkishore Mitra , Donald Masquelier , Anthony Makarewicz , Christopher Hindson , Benjamin Hindson , Serge Saxonov
Abstract: The disclosure provides devices, systems and methods for the generation of encapsulated reagents and the partitioning of encapsulated reagents for use in subsequent analyses and/or processing, such as in the field of biological analyses and characterization.
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公开(公告)号：US20190203291A1
公开(公告)日：2019-07-04
申请号：US16294769
申请日：2019-03-06
Applicant: 10X GENOMICS, INC.
Inventor： Benjamin Hindson , Christopher Hindson , Michael Schnall-levin , Kevin Ness , Mirna Jarosz , Serge Saxonv , Paul Hardenbol , Rajiv Bharadwaj , Xinying Zheng , Phillip Belgrader
IPC: C12Q1/6874 , C12Q1/6869 , C12Q1/6806 , C12Q1/6855
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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公开(公告)号：US20180363029A1
公开(公告)日：2018-12-20
申请号：US16056231
申请日：2018-08-06
Applicant: 10X Genomics, Inc.
Inventor： Benjamin Hindson , Christopher Hindson , Michael Schnall-Levin , Kevin Ness , Mirna Jarosz , Donald Masquelier , Serger Saxonov , Landon Merrill , Andrew Price , Paul Hardenbol , Yuan Li
IPC: C12Q1/6806 , C12N15/10
Abstract: This disclosure provides methods and compositions for sample processing, particularly for sequencing applications. Included within this disclosure are bead compositions, such as diverse libraries of beads attached to large numbers of oligonucleotides containing barcodes. Often, the beads provides herein are degradable. For example, they may contain disulfide bonds that are susceptible to reducing agents. The methods provided herein include methods of making libraries of barcoded beads as well as methods of combining the beads with a sample, such as by using a microfluidic device.
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Patent Agency Ranking
公开(公告)号：US10150964B2
公开(公告)日：2018-12-11
申请号：US15693374
申请日：2017-08-31
Applicant: 10X GENOMICS, INC.
Inventor： Benjamin Hindson , Serge Saxonov , Kevin Ness , Paul Hardenbol , Christopher Hindson , Donald Masquelier , Mirna Jarosz , Michael Schnall-Levin
IPC: C12Q1/68 , C12P19/34 , C12N15/10 , C12Q1/6806 , C12N15/11 , C12Q1/6876 , G01N33/543 , C12Q1/6874
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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127.发明授权公开(公告)号：US10137449B2
公开(公告)日：2018-11-27
申请号：US15717840
申请日：2017-09-27
Applicant: 10X Genomics, Inc.
Inventor： Rajiv Bharadwaj , Kevin Ness , Debkishore Mitra , Donald Masquelier , Anthony Makarewicz , Christopher Hindson , Benjamin Hindson , Serge Saxonov
Abstract: The disclosure provides devices, systems and methods for the generation of encapsulated reagents and the partitioning of encapsulated reagents for use in subsequent analyses and/or processing, such as in the field of biological analyses and characterization.
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公开(公告)号：US20180327839A1
公开(公告)日：2018-11-15
申请号：US16045474
申请日：2018-07-25
Applicant: 10X Genomics, Inc.
Inventor： Benjamin Hindson , Christopher Hindson , Michael Schnall-Levin , Kevin Ness , Mirna Jarosz , Serge Saxonov
IPC: C12Q1/6874 , C12Q1/683 , C12Q1/6806
CPC classification number: C12Q1/6874 , C12Q1/6804 , C12Q1/6806 , C12Q1/683 , C12Q2525/191 , C12Q2535/122 , C12Q2537/143 , C12Q2537/149 , C12Q2563/149 , C12Q2563/159 , C12Q2563/179 , C12Q2565/629
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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公开(公告)号：US20180282803A1
公开(公告)日：2018-10-04
申请号：US15933299
申请日：2018-03-22
Applicant: 10X GENOMICS, INC.
Inventor： Phillip Belgrader , Zachary Bent , Rajiv Bharadwaj , Vijay Kumar Sreenivasa Gopalan , Josephine Harada , Christopher Hindson , Mohammad Rahimi Lenji , Michael Ybarra Lucero , Geoffrey McDermott , Elliott Meer , Tarjei Sigurd Mikkelsen , Christopher Joachim O'Keeffe , Katherine Pfeiffer , Andrew D. Price , Paul Ryvkin , Serge Saxonov , John R. Stuelpnagel , Jessica Michele Terry , Tobias Daniel Wheeler , Indira Wu , Solongo Batjargal Ziraldo
IPC: C12Q1/6874 , C12Q1/683 , C12Q1/6806
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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公开(公告)号：US20180258482A1
公开(公告)日：2018-09-13
申请号：US15980473
申请日：2018-05-15
Applicant: 10X GENOMICS, INC.
Inventor： Benjamin Hindson , Christopher Hindson , Michael Schnall-Levin , Kevin Ness , Mima Jarosz , Serge Saxonov , Paul Hardenbol , Rajiv Bharadwaj , Xinying Zheng , Phillip Belgrader
IPC: C12Q1/6874 , C12Q1/683 , C12Q1/6804 , C12Q1/6806
CPC classification number: C12Q1/6874 , C12Q1/6804 , C12Q1/6806 , C12Q1/683 , C12Q2525/191 , C12Q2537/143 , C12Q2563/179 , C12Q2535/122 , C12Q2563/149 , C12Q2563/159 , C12Q2565/629
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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