公开(公告)号：US06241728B1

公开(公告)日：2001-06-05

申请号：US09395123

申请日：1999-09-14

Applicant: John W. Gaiser ,  Hong Li

Inventor： John W. Gaiser ,  Hong Li

IPC: A61B1814

CPC classification number: A61B18/1492 ,  A61B18/1815 ,  A61B2017/003 ,  A61B2017/00867 ,  A61B2018/00577 ,  A61B2018/1253 ,  A61B2018/1467 ,  C08L2201/12

Abstract: A left atrium ablation catheter (4), including a sheath (8) and a deflectable electrophysiology catheter (10) housed within the sheath, is used to ablate coronary tissue at a target site within the left atrium (LA) of a heart. The electrophysiology catheter has ablation electrodes (24) along the tip (10). The ablation catheter is introduced into the right atrium (RA) through either the superior vena cava (SVC) or the inferior vena cava (IVC). The distal open end of the sheath is guided through a punctured hole in the interatrial septum and into the left atrium. The distal end (20) of the sheath is either precurved or is steerable so the electrode tip can be directed to the coronary target site in the left atrium. The electrode tip is sized and configured to create the desired lesion at the target site without movement of the electrode tip.

Abstract translation: 包括护套（8）和容纳在护套内的可偏转电生理学导管（10）的左心房消融导管（4）用于在心脏的左心房（LA）内的靶位置消融冠状组织。 电生理学导管具有沿尖端（10）的消融电极（24）。 消融导管通过上腔静脉（SVC）或下腔静脉（IVC）引入右心房（RA）。 护套的远端开口端引导穿过房间隔中的穿刺孔并进入左心房。 鞘的远端（20）是预先的或是可操纵的，使得电极尖端可以被引导到左心房中的冠状动脉靶位点。 电极头的尺寸和构造可以在靶位置产生所需的损伤，而不会移动电极尖端。

公开(公告)号：US06241722B1

公开(公告)日：2001-06-05

申请号：US09098447

申请日：1998-06-17

Applicant: John D. Dobak ,  Hong Li

Inventor： John D. Dobak ,  Hong Li

IPC: A61B1818

CPC classification number: A61B18/02 ,  A61B2017/00243 ,  A61B2018/00196 ,  A61B2018/0212 ,  A61B2018/0268 ,  A61B2090/0463

Abstract: The present invention provides a cryogenic device and system for treating biological tissue, which includes at least two media-flow lumens and a media-expansion element for cooling media flowing within the device. A cooling portion of the device is located along a portion of one of the media-flow lumens. The cooling portion is of a construction suitable for good contact with tissue selected for treatment. Preferably, the device and system employ one or more closed media-flow pathways for efficient recycling of the media employed. Preferably, the device and system also employ efficacious heat-exchange relationships between media-flow conduits for optimal cooling. The device and system are particularly designed for the formation of lesions in biological tissue, most particularly, the formation of deep, elongated and continuous lesions in cardiopulmonary tissue. The present invention also provides a method of using the cryogenic device and system in the treatment of biological tissue.

Abstract translation: 本发明提供一种用于治疗生物组织的低温装置和系统，其包括至少两个介质流动腔和用于冷却在装置内流动的介质的介质 - 膨胀元件。 装置的冷却部分沿着一个介质流动腔的一部分定位。 冷却部分是适于与选择用于治疗的组织良好接触的结构。 优选地，装置和系统采用一个或多个封闭的介质流动路径，以有效地回收所使用的介质。 优选地，装置和系统还在介质流动管道之间采用有效的热交换关系以实现最佳冷却。 该装置和系统特别设计用于在生物组织中形成损伤，最特别地，在心肺组织中形成深的，细长的和连续的损伤。 本发明还提供了一种使用该低温装置和系统来处理生物组织的方法。

公开(公告)号：US06193287B1

公开(公告)日：2001-02-27

申请号：US09318424

申请日：1999-05-25

Applicant: Hong Li ,  Daniel J. Lecinski ,  Kenneth S. Laughlin

Inventor： Hong Li ,  Daniel J. Lecinski ,  Kenneth S. Laughlin

IPC: E05C106

CPC classification number: B22F9/007 ,  B22F2998/10 ,  C22C33/003 ,  C22C33/04 ,  C22C45/02 ,  Y10S292/07 ,  Y10T292/084 ,  Y10T292/0982 ,  B22F9/008 ,  B22F3/115

Abstract: An electronic chassis door locking apparatus includes an electronic chassis door and a locking assembly. The electronic chassis door includes a recessed region formed therein. The recessed region is positioned adjacent a latch. The latch is operably attached to the electronic chassis door. The locking assembly is received in the recessed region, and includes a lock screw and a lock cam. The lock cam includes a first opening and an engaging portion. The engaging portion allows for engagement with the latch.

Abstract translation: 电子底盘门锁装置包括电子底盘门和锁定组件。 电子底盘门包括形成在其中的凹陷区域。 凹陷区域位于闩锁附近。 闩锁可操作地附接到电子底盘门。 锁定组件被容纳在凹陷区域中，并且包括锁定螺钉和锁定凸轮。 锁定凸轮包括第一开口和接合部分。 接合部分允许与闩锁接合。

公开(公告)号：US5836990A

公开(公告)日：1998-11-17

申请号：US934286

申请日：1997-09-19

Applicant: Hong Li

Inventor： Hong Li

IPC: A61B5/05 ,  A61N1/05 ,  A61N1/08

CPC classification number: A61N1/056 ,  A61N1/08 ,  A61B2018/00875 ,  A61B2090/065 ,  A61B5/05

Abstract: Contact between an electrophysiology catheter electrode (6) and cardiac tissue covered by blood is sensed by applying a constant voltage or current square wave signal (23) to the electrode and then monitoring the voltage or impedance or current at the electrode before, during, and after the electrode contacts the tissue. The monitored pulse (22) includes an ohmic impedance portion (30) and combined ohmic and capacitive impedance portion (32). Successive monitored pulses can be measured in several ways to determine when tissue contact has occurred: the maximum magnitudes (36) of successive ohmic resistance portions; the initial slopes (38) for successive combined resistive portions; the amplitudes (40) of successive combined resistive portions at a preset time interval from the start of each pulse; and the average amplitudes (42) of successive combined impedance portions over a preset time period for each pulse. Upon contact, the magnitudes of each changes significantly, such as 40-50% in cardiac applications.

Abstract translation: 通过向电极施加恒定电压或电流方波信号（23），然后监测电极之前，期间和之后的电压或阻抗或电流，来检测电生理学导管电极（6）和被血液覆盖的心脏组织之间的接触。 电极接触组织后。 所监视的脉冲（22）包括欧姆阻抗部分（30）和组合的欧姆和电容阻抗部分（32）。 可以以几种方式测量连续的监测脉冲，以确定何时发生组织接触：连续欧姆电阻部分的最大幅度（36） 用于连续组合电阻部分的初始斜面（38） 连续的组合电阻部分的幅度（40）在从每个脉冲开始的预设时间间隔处; 以及在每个脉冲的预设时间段内的连续组合阻抗部分的平均振幅（42）。 接触后，每个人的心律变化显着，例如心脏应用中的40-50％。

公开(公告)号：US5716390A

公开(公告)日：1998-02-10

申请号：US695042

申请日：1996-08-09

Applicant: Hong Li

Inventor： Hong Li

IPC: A61N1/05 ,  A61N1/04

CPC classification number: A61N1/056 ,  A61N1/0573

Abstract: A body implantable flexible lead assembly, adapted to transmit electrical pulses between a proximal end of the lead assembly and a distal end of the assembly to stimulate selected body tissue, includes a tubular, insulating housing connecting the proximal and distal ends of the assembly and having a central, longitudinal axis. At least two coiled, insulated conductors extend between the proximal and distal ends of the assembly for transmitting electrical signals, the coils of the at least two insulated conductors having substantially the same diameter. One of the coiled conductors is rotatable about the longitudinal axis relative to the other coiled conductor(s) and has a proximal end and a distal end. Last, a helix electrode is electrically connected to the distal end of the one coiled conductor for piercing the tissue to be stimulated, the one coiled conductor being adapted to extend or retract the helix electrode relative to the distal end of the assembly through rotation of the proximal end of the one coiled conductor.

Abstract translation: 适于在引线组件的近端和组件的远端之间传递电脉冲以刺激所选择的身体组织的主体可植入柔性引线组件包括连接组件的近端和远端的管状绝缘壳体，并具有 中心的纵轴。 至少两个卷绕的绝缘导体在组件的近端和远端之间延伸以传输电信号，所述至少两个绝缘导体的线圈具有基本上相同的直径。 线圈导体中的一个可相对于另一个卷绕的导体围绕纵向轴线旋转，并且具有近端和远端。 最后，螺旋电极电连接到一个线圈导体的远端，用于刺穿被刺激的组织，一个线圈导体适于通过旋转的方式使螺旋电极相对于组件的远端延伸或缩回 一个线圈导体的近端。

公开(公告)号：US5446886A

公开(公告)日：1995-08-29

申请号：US031207

申请日：1993-03-12

Applicant: Hong Li

Inventor： Hong Li

IPC: G06F12/00 ,  G06F17/30

CPC classification number: G06F17/30498 ,  G06F17/30545 ,  Y10S707/966 ,  Y10S707/99932 ,  Y10S707/99939

Abstract: A distributed database system includes a communication network having a plurality of nodes each with a distributed database, a local process part for extracting relations from each database by performing local processes at each node when a query including multi-attribute relations thereof is input, a degree setting part for setting a degree number of each of the extracted relations, a relation set part for arranging relation sets each containing relations having the same degree number by grouping the extracted relations according to the degree number, an extraction part for extracting single-attribute relations from each relation set so that the single-attribute relations are added to a first relation set having the lowest degree number, a semijoin operating part for repeatedly semijoining two relations of a only relation set only when the quantity of transfer data resulting from the semijoining is decreased, so that a derived relation is added to a next relation set, and a control part for allowing the semijoin operating part to sequentially perform the semijoining and adding so that each derived relation is added to the transfer data.

Abstract translation: 分布式数据库系统包括具有多个节点的通信网络，每个节点均具有分布式数据库;本地处理部分，用于当输入包括其多属性关系的查询时，通过在每个节点执行本地进程从每个数据库提取关系; 设置部分，用于设置提取的关系中的每个提取的关系的程度数，用于通过根据度数对所提取的关系进行分组而将包含具有相同度数的关系的关系集合的关系集合部分，用于提取单属性关系的提取部 从每个关系集合，使得单个属性关系被添加到具有最低度数的第一关系集合;半连接操作部分，用于仅当从半连接产生的传输数据的数量为重复地将仅关联集合的两个关系设置为半 减少，使得派生关系被添加到下一个关系集合，以及控制参数 t允许半连接操作部分顺序地执行半连接和相加，使得将每个派生关系添加到传送数据。

公开(公告)号：US5378330A

公开(公告)日：1995-01-03

申请号：US59466

申请日：1993-05-07

Applicant: Hong Li ,  Stephen D. Senturia ,  David Volfson

Inventor： Hong Li ,  Stephen D. Senturia ,  David Volfson

IPC: C25F3/16 ,  C25F3/24

CPC classification number: C25F3/16 ,  C25F3/24

Abstract: A method for polishing a substrate having at least one micro-sized structure. The method includes identifying a first region of the substrate on which a micro-sized structure is to be located. The first region is the region in which polishing is desired. A second region of the substrate, in which polishing is not desired, is also identified. An adhesion promoter is optionally applied to the substrate. The second region of the substrate is coated with a selected coating material that does not degrade substantially when exposed to a selected electrolyte. Material is removed from the first region, exposing a micro-sized structure. The coating material may be removed by the same machining process that forms the micro-sized structure. The substrate is submerged in the selected electrolyte so that the first region is exposed to the electrolyte. The first region of the substrate is electropolished. The coating is then optionally removed.

Abstract translation: 一种用于抛光具有至少一个微尺寸结构的衬底的方法。 该方法包括识别在其上定位有微尺寸结构的基底的第一区域。 第一区域是需要抛光的区域。 还鉴定了不需要抛光的衬底的第二区域。 任选地将粘合促进剂施加到基底上。 衬底的第二区域涂覆有当暴露于所选择的电解质时不会显着降解的选择的涂层材料。 从第一区域去除材料，暴露微尺寸结构。 可以通过形成微尺寸结构的相同的加工工艺去除涂层材料。 将衬底浸没在所选择的电解质中，使得第一区域暴露于电解质。 电解抛光底物的第一区域。 然后可选地除去涂层。

公开(公告)号：US5286944A

公开(公告)日：1994-02-15

申请号：US856237

申请日：1992-03-25

Applicant: Hong Li

Inventor： Hong Li

IPC: B23K15/08 ,  B23K26/36 ,  B23K15/00 ,  B23H5/10 ,  B23K26/00 ,  H01R43/00

CPC classification number: B23K15/08 ,  B23K26/362 ,  B01J2219/00653 ,  Y10T29/49117 ,  Y10T29/49224 ,  Y10T29/49982

Abstract: A method of manufacturing a multiple microelectrode assembly is disclosed. Micromachining technology (such as micro-electrical-discharge machining technology, laser-beam micromachining, electron-beam micromachining) is used to manufacture an electrode/base assembly. The electrode/base assembly is placed within a container; a liquid material is placed into the container; the liquid material surrounds the electrodes of the electrode/base assembly and is allowed to solidify; and the solidified liquid material in combination with the electrode/base assembly is separated from the container. The bottom (or base) portion of the electrode/base assembly is then removed. The electrodes of the electrode/base assembly comprise a plurality of rod-like members of very small (on the order of 1 micron) metallic members of preselected dimension, shape and spacing, by which they are adapted in combination with the surrounding insulating material as a multiple microelectrode assembly.

Abstract translation: 公开了一种制造多微电极组件的方法。 微加工技术（如微放电加工技术，激光束加工，电子束微加工）用于制造电极/基座组件。 电极/基座组件放置在容器内; 将液体材料放入容器中; 液体材料围绕电极/基座组件的电极并被固化; 并且与电极/基座组件组合的固化液体材料与容器分离。 然后去除电极/基座组件的底部（或底座）部分。 电极/基座组件的电极包括非常小（约1微米）的预定尺寸，形状和间距的金属构件的多个杆状构件，通过它们与周围的绝缘材料组合适应 多个微电极组件。

公开(公告)号：USD1040316S1

公开(公告)日：2024-08-27

申请号：US29940171

申请日：2024-04-30

Applicant: Hong Li

Designer： Hong Li

Abstract: FIG. 1 is a front, right and top perspective view of a neck fan, showing my new design;
FIG. 2 is a rear, left and bottom perspective view thereof;
FIG. 3 is a front view thereof;
FIG. 4 is a rear view thereof;
FIG. 5 is a left side view thereof;
FIG. 6 is a right side view thereof;
FIG. 7 is a top plan view thereof;
FIG. 8 is a bottom plan view thereof; and,
The broken lines shown in the drawings illustrate portions of the neck fan that form no part of the claimed design.

公开(公告)号：US20240009118A1

公开(公告)日：2024-01-11

申请号：US18350357

申请日：2023-07-11

Applicant: Hong Li ,  Kenneth C. Elliott

Inventor： Hong Li ,  Kenneth C. Elliott

IPC: A61K9/00 ,  A61K39/215 ,  A61K47/42 ,  A61K47/36 ,  A61P31/14

CPC classification number: A61K9/0056 ,  A61K39/215 ,  A61K9/0048 ,  A61K47/42 ,  A61K47/36 ,  A61P31/14 ,  A61K2039/552

Abstract: The invention provides a method for vaccinating one or more avians in need thereof. The vaccination method comprises administering to the one or more avians a stable foam in an amount effective for inducing a neutralizing immune response against an infectious pathogen in the one or more avians. The foam comprises a gas and a liquid, and the liquid comprises a vaccine and a foaming agent. The avian may be a chick. Also provided is a method for preparing the stable foam.