SUSTAINED-RELEASE SOLID PREPARATION FOR ORAL USE
    121.
    发明申请
    SUSTAINED-RELEASE SOLID PREPARATION FOR ORAL USE 审中-公开
    持续释放用于口服使用的固体制剂

    公开(公告)号:US20130004550A1

    公开(公告)日:2013-01-03

    申请号:US13591902

    申请日:2012-08-22

    摘要: It is intended to avoid dose dumping of a drug and improve the dissolution properties of the drug in the lower gastrointestinal tract, and thereby provide a sustained-release matrix preparation for oral administration that reliably exhibits its main pharmacological effect when orally administered once or twice a day. The present invention provides a sustained-release preparation obtained by mixing of (A) a pharmacologically active drug, (B) hydroxypropyl methylcellulose acetate succinate having a median size (D50) of 40 μm or smaller, (C) a cellulose derivative, and (D) a saccharide or a nonionic water-soluble polymer followed by molding.

    摘要翻译: 旨在避免药物的剂量倾倒并改善药物在下胃肠道中的溶解性质,从而提供口服给药的缓释基质制剂,其可口服给药一次或两次可靠地显示其主要药理作用 天。 本发明提供一种缓释制剂,其通过将(A)药理活性药物(B)中等尺寸(D50)为40μm以下的乙酸琥珀酸羟丙基甲基纤维素,(C)纤维素衍生物和( D)糖或非离子水溶性聚合物,随后成型。

    Alicyclic epoxy resin composition, cured product thereof, production method thereof, and rubbery polymer-containing resin composition
    122.
    发明授权
    Alicyclic epoxy resin composition, cured product thereof, production method thereof, and rubbery polymer-containing resin composition 有权
    脂环族环氧树脂组合物,其固化产物,其制备方法和含橡胶聚合物的树脂组合物

    公开(公告)号:US08278388B2

    公开(公告)日:2012-10-02

    申请号:US12864968

    申请日:2009-01-27

    摘要: It is an object of the invention to provide a rubbery polymer-containing resin composition useful as a raw material for a molded article and a cured product having high transparency and excellent mechanical strength: namely, an object of the invention is to provide, for example, a cycloaliphatic epoxy resin composition capable of improving the toughness thereof while maintaining the mechanical strength and transparency of the cycloaliphatic epoxy resin without lowering the heat resistance, a production method thereof and a cured product thereof. A rubbery polymer-containing resin composition of the invention, for example, a cycloaliphatic epoxy resin composition of the invention is a cycloaliphatic epoxy resin composition comprising 100 parts by weight of a cycloaliphatic epoxy resin and 1 to 60 parts by weight of polymer particles with a volume average particle diameter (Mv) of not smaller than 0.01 μm and not larger than 0.5 μm, characterized in that each of the polymer particles comprises at least two layers of an elastic core layer present in the inside thereof and a shell layer present in the outermost side thereof, the elastic core layer consisting of a rubbery polymer with a glass transition temperature of lower than 10° C., and the composition is colorless and transparent.

    摘要翻译: 本发明的目的是提供一种可用作模制品的原料的含橡胶聚合物的树脂组合物和具有高透明度和优异的机械强度的固化产物,即本发明的目的是提供例如 ,能够在不降低耐热性的同时保持脂环族环氧树脂的机械强度和透明性的同时提高其韧性的脂环族环氧树脂组合物,其制备方法和其固化产物。 本发明的含橡胶聚合物的树脂组合物,例如本发明的脂环族环氧树脂组合物是脂环族环氧树脂组合物,其包含100重量份的脂环族环氧树脂和1至60重量份的具有 体积平均粒径(Mv)不小于0.01μm且不大于0.5μm,其特征在于,每个聚合物颗粒包含至少两层存在于其内部的弹性芯层和存在于其中的壳层 其最外侧,弹性芯层由玻璃化转变温度低于10℃的橡胶状聚合物构成,组合物无色透明。

    Ceramic capacitor and electronic component including the same
    124.
    发明授权
    Ceramic capacitor and electronic component including the same 有权
    陶瓷电容器和包括其的电子部件

    公开(公告)号:US08233265B2

    公开(公告)日:2012-07-31

    申请号:US12617823

    申请日:2009-11-13

    IPC分类号: H01G4/228 H01G4/06

    摘要: In a ceramic capacitor, first and second electrode terminals each include a bonded-to-substrate portion, a first bonded-to-electrode portion bonded to a first edge of one of first and second external electrodes, a second bonded-to-electrode portion bonded to a second edge of the one of first and second external electrodes and disposed at a distance from the first bonded-to-electrode portion in the first directions, and a connecting portion connecting the first and second bonded-to-electrode portions and the bonded-to-substrate portion. W1/W0 is about 0.3 or more, and h/L is about 0.1 or more.

    摘要翻译: 在陶瓷电容器中,第一和第二电极端子各自包括接合到衬底部分,第一接合电极部分接合到第一和第二外部电极之一的第一边缘,第二接合电极部分 接合到第一外部电极和第二外部电极中的一个的第二边缘并且在第一方向上与第一接合电极部分设置一定距离,以及连接第一和第二接合电极部分和第二接合电极部分的连接部分, 键合到衬底部分。 W1 / W0为约0.3以上,h / L约为0.1以上。

    GLASS FIBER-SILSESQUIOXANE COMPOSITE MOLDED ARTICLE AND METHOD FOR PRODUCING SAME
    125.
    发明申请
    GLASS FIBER-SILSESQUIOXANE COMPOSITE MOLDED ARTICLE AND METHOD FOR PRODUCING SAME 有权
    玻璃纤维 - 硅树脂复合材料制品及其生产方法

    公开(公告)号:US20120052296A1

    公开(公告)日:2012-03-01

    申请号:US13264535

    申请日:2010-04-14

    IPC分类号: B32B1/00 B05D3/06 B05D3/00

    摘要: Disclosed is a glass fiber-silsesquioxane composite molded article containing glass fibers and a cured material of a silsesquioxane polymer composited therewith, wherein the silsesquioxane has a polyhedral structure or a partially polyhedral structure. The glass fiber-silsesquioxane composite molded article is preferably obtained by impregnating glass fibers with a composition containing at least one of silsesquioxanes represented by formula (A-1) to (A-3) and at least one of a curing agent, a polymerization initiator, and a hydrosilylation catalyst, or the silsesquioxane polymer and allowing a curing reaction to proceed.

    摘要翻译: 公开了一种玻璃纤维 - 倍半硅氧烷复合模塑制品,其包含玻璃纤维和与其复合的倍半硅氧烷聚合物的固化材料,其中倍半硅氧烷具有多面体结构或部分多面体结构。 玻璃纤维 - 倍半硅氧烷复合成型体优选通过将由式(A-1)〜(A-3)表示的倍半硅氧烷中的至少一种组成的玻璃纤维浸渍到固化剂,聚合引发剂 ,和氢化硅烷化催化剂或倍半硅氧烷聚合物,并进行固化反应。

    Process for the preparation of sulfomate-carboxylate derivatives
    126.
    发明授权
    Process for the preparation of sulfomate-carboxylate derivatives 失效
    磺胺甲酸酯衍生物的制备方法

    公开(公告)号:US08115030B2

    公开(公告)日:2012-02-14

    申请号:US11909980

    申请日:2006-03-30

    IPC分类号: C07C303/00

    摘要: Disclosed is a process for the preparation of Compound (III), salt or solvate thereof by reacting Compound (I), salt or solvate thereof with Compound (II) in a toluene solvent in the presence of an additive such as water or an alcohol. Also disclosed is a process for the preparation of Compound (IV) comprising hydrolyzing the obtained Compound (III) if necessary, and then oxidizing. In the formula, R1 is hydrogen, optionally substituted lower alkyl, optionally substituted aryl or optionally substituted aryl lower alkyl, and R2 is optionally substituted lower alkyl, optionally substituted cycloalkyl or optionally substituted aryl lower alkyl.

    摘要翻译: 公开了在添加剂如水或醇的存在下,使化合物(I),其盐或溶剂合物与化合物(II)在甲苯溶剂中反应制备化合物(III),其盐或溶剂化物的方法。 还公开了制备化合物(Ⅳ)的方法,包括如果需要水解得到的化合物(III),然后进行氧化。 在该式中,R 1是氢,任选取代的低级烷基,任选取代的芳基或任选取代的芳基低级烷基,R 2是任选取代的低级烷基,任选取代的环烷基或任选取代的芳基低级烷基。

    GAME SYSTEM AND SERVER
    128.
    发明申请
    GAME SYSTEM AND SERVER 失效
    游戏系统和服务器

    公开(公告)号:US20100261535A1

    公开(公告)日:2010-10-14

    申请号:US12678760

    申请日:2008-08-22

    IPC分类号: A63F9/24

    摘要: A game system for reliably realizing synchronization of timings at which a common event in a plurality of game machines start. The game system includes a plan management server that measures lapse of system time common in the game system and with the time measurement, updates plan information indicative of remaining time until the system time reaches a process start stage at which a process for the common event starts. Each of the game machines includes an obtaining device to obtain the plan information from the plan management server, a stage determining device to determine whether the system time has reached the process start stage or not on the basis of laps of time of the system time measured in the game machine, and a process executing device to start a process for the common event when it is determined that the system time has reached the process start stage.

    摘要翻译: 一种用于可靠地实现多个游戏机中的共同事件开始的定时的同步的游戏系统。 该游戏系统包括计算管理服务器,该计划管理服务器测量游戏系统中常见的系统时间的流逝,并且通过时间测量,更新指示剩余时间的计划信息,直到系统时间到达共同事件的处理开始的处理开始阶段 。 每个游戏机包括从计划管理服务器获得计划信息的获取装置,阶段确定装置,用于基于所测量的系统时间的时间段来确定系统时间是否已经达到处理开始阶段 以及当确定系统时间已经到达处理开始阶段时,处理执行装置开始用于公共事件的处理。

    ICE MAKING WATER TANK FOR AUTOMATIC ICE MAKING MACHINE
    129.
    发明申请
    ICE MAKING WATER TANK FOR AUTOMATIC ICE MAKING MACHINE 审中-公开
    制冰机自动制冰机

    公开(公告)号:US20100139305A1

    公开(公告)日:2010-06-10

    申请号:US12733098

    申请日:2008-06-05

    IPC分类号: F25C1/00 F16K31/18 E03B11/00

    摘要: The object is to provide an ice making water tank for an automatic ice making machine capable of stabilizing the operation of a float switch. As a means for achieving the object, there is provided an overflow portion 64 having a wall portion 58 to define a maximum water storage level of ice making water, and a raised-bottom portion 60 to discharge excess ice making water that has overflowed the wall portion 58 to the outside through a discharge port 62 on a side near the outside of a tank portion 52 of an ice making water tank 32. Furthermore, a partition member 68 is removably disposed on the overflow portion 64 side with respect to the disposed position of the circulation pump 14 in the tank portion 52 to divide the inside of the tank portion 52 into two regions, and to allow ice making water near the bottom portion 56 to flow between the two regions. In addition, a float switch 26 is disposed between the partition member 68 and the overflow portion 64 in the tank portion 52.

    摘要翻译: 本发明的目的是提供一种能够稳定浮子开关的操作的自动制冰机的制冰水箱。 作为实现该目的的手段,设置有溢流部分64,该溢流部分64具有壁部分58以限定制冰水的最大贮水量;以及升高底部部分60,以排出多余的制冰水, 部分58通过制冰水箱32的罐部分52的外侧附近的排出口62向外部延伸。此外,分隔构件68相对于设置位置可移除地设置在溢流部64侧 在槽部分52中的循环泵14将罐部分52的内部分成两个区域,并允许底部56附近的制冰水在两个区域之间流动。 此外,浮子开关26设置在槽部分52中的分隔构件68和溢流部分64之间。

    Silsesquioxane derivative and production process for the same
    130.
    发明授权
    Silsesquioxane derivative and production process for the same 有权
    倍半硅氧烷衍生物和生产工艺相同

    公开(公告)号:US07449539B2

    公开(公告)日:2008-11-11

    申请号:US11545594

    申请日:2006-10-11

    IPC分类号: C07F7/21

    摘要: The present inventors have obtained a PSQ derivative of a completely condensed type into which a functional group is readily introduced by using a novel PSQ derivative of an incompletely condensed type in which four alkaline metal atoms are bonded to silsesquioxane of a cage type having eight Si's. The above silsesquioxane derivative is represented by Formula (1). A silsesquioxane derivative to which alkaline metal atoms are bonded is represented by Formula (2). In Formula (1) and Formula (2), R is a group selected from alkyl, aryl and arylalkyl; Y is a group represented by Formula (a) or Formula (b); and M is a monovalent alkaline metal atom. X in Formula (a) and Formula (b) is hydrogen, halogen, a hydroxyl group or a monovalent organic group, and Z is —O—, —CH2— or a single bond. The preferred organic group is a functional group or a group having a functional group.

    摘要翻译: 本发明人已经获得了一种完全冷凝型的PSQ衍生物,其中通过使用四种碱金属原子与具有八个Si的笼型的倍半硅氧烷结合的不完全冷凝型的新型PSQ衍生物容易地引入官能团。 上述倍半硅氧烷衍生物由式(1)表示。 碱金属原子键合的倍半硅氧烷衍生物由式(2)表示。 在式(1)和式(2)中,R是选自烷基,芳基和芳烷基的基团; Y为式(a)或式(b)所示的基团。 M为单价碱金属原子。 式(a)和式(b)中的X为氢,卤素,羟基或一价有机基团,Z为-O-,-CH 2 - 或单键。 优选的有机基团是官能团或具有官能团的基团。