公开(公告)号：US09649027B2

公开(公告)日：2017-05-16

申请号：US14431450

申请日：2013-09-27

申请人： CARL ZEISS MEDITEC AG

发明人： Ralf Ebersbach ,  Martin Hacker ,  Gerard Antkowiak ,  Peter Klopfleisch ,  Ferid Bajramovic ,  Tobias Bühren ,  Matthias Reich

IPC分类号： A61B3/107 ,  A61B3/117 ,  A61B3/10

CPC分类号： A61B3/107 ,  A61B3/1005 ,  A61B3/102 ,  A61B3/1173

摘要： A device for determining biometric variables of the eye, as are incorporated in the calculation of intraocular lenses including a multi-point keratometer and an OCT arrangement. The keratometer measurement points are illuminated telecentrically and detected telecentrically and the OCT arrangement is designed as a laterally scanning swept-source system with a detection region detecting the whole eye over the whole axial length thereof. The multi-point keratometer ensures that a sufficient number of keratometer points are available for measuring the corneal surface. By contrast, telecentricity ensures that the positioning inadequacies of the measuring instrument in relation to the eye to be measured do not lead to a local mismatch of the reflection points. The swept-source OCT scan detects the whole eye over the length thereof so that both anterior chamber structures and retina structures can be detected and a consistent whole eye image can be realized.

公开(公告)号：US09610154B2

公开(公告)日：2017-04-04

申请号：US14359878

申请日：2012-11-20

申请人： Carl Zeiss Meditec AG

发明人： Brian Rathert

IPC分类号： A61F2/16

CPC分类号： A61F2/167 ,  A61F2/1662

摘要： The invention concerns an injector tip (7) for an ocular lens injector device (1), the injector tip having an injection duct (16) with a front (9) and a rear end (8) and being bounded by an inner wall (17), wherein at the inner wall (17) an inwardly extending step (18) is formed only along part of the entire length between the front (9) and the rear end (8) of the injection duct (16) and ends at a distance from the front end (9) of the injection duct (16). The invention also relates to an ocular lens injector device (1) with an injector tip (7).

公开(公告)号：US09603701B2

公开(公告)日：2017-03-28

申请号：US10590430

申请日：2005-04-06

申请人： Andreas Obrebski

发明人： Andreas Obrebski

IPC分类号： A61F2/16

CPC分类号： A61F2/1613 ,  A61F2/1635 ,  A61F2250/0018

摘要： An artificial lens for an eye (10) is described. According to the present invention, an artificial lens for an eye is now provided, in which the focal width can change. This is realized according to the invention by providing the artificial lens with two or more media (12, 13) that are flexible in shape as lens elements and that the two media that are flexible in shape stand in direct contact with one another. The media that are flexible in shape are preferably disposed in an uptake container forming a lens body (11).

公开(公告)号：US09579019B2

公开(公告)日：2017-02-28

申请号：US14862366

申请日：2015-09-23

申请人： Carl Zeiss Meditec AG

发明人： Marco Wilzbach ,  Markus Seesselberg

IPC分类号： A61B3/10 ,  A61B3/00 ,  A61B3/13 ,  A61B3/103 ,  A61B3/107 ,  A61B3/16 ,  A61F9/007

CPC分类号： A61B3/13 ,  A61B3/0075 ,  A61B3/1015 ,  A61B3/103 ,  A61B3/107 ,  A61B3/16 ,  A61F9/00736 ,  A61F9/00745

摘要： A method of operating an eye surgery system comprises operating actuators of a stand such that an apparatus for measuring the refraction of an eye is located in a measurement position relative to the eye; measuring at least one condition of the eye and determining at least one condition value representing the at least one measured condition of the eye; measuring the refraction of the eye and determining at least one refraction value presenting the measured refraction of the eye, wherein a time distance between the measuring of the condition of the eye and the measuring of the refraction of the eye is smaller than a predetermined duration; and outputting the at least one refraction value representing the measured refraction of the eye only when the condition value representing the measured condition of the eye is within a predetermined range of values.

摘要翻译： 操作眼科手术系统的方法包括操作支架的致动器，使得用于测量眼睛折射的装置位于相对于眼睛的测量位置; 测量眼睛的至少一个状况并确定代表眼睛的至少一个测量状态的至少一个条件值; 测量眼睛的折射并确定呈现所测量的眼睛的折射的至少一个折射值，其中测量眼睛状况和测量眼睛的折射之间的时间距离小于预定的持续时间; 并且只有当表示眼睛的测量条件的条件值在预定值范围内时，才输出表示眼睛测量的折射的至少一个折射值。

公开(公告)号：US09568722B2

公开(公告)日：2017-02-14

申请号：US14752693

申请日：2015-06-26

申请人： Carl Zeiss Meditec AG

发明人： Peter Reimer ,  Daniel Kolster ,  Franz Merz ,  Stefan Meinkuss

IPC分类号： G02B21/06 ,  G02B21/08 ,  G02B21/12 ,  G02B21/00

CPC分类号： G02B21/06 ,  G02B21/0012 ,  G02B21/082 ,  G02B21/125

摘要： An illumination device for an optical viewing apparatus has a light source including a first individual light source and a second individual light source arranged in a plane. The first individual light source has a first midpoint and the second individual light source has a second midpoint. An axial direction is defined by a vector from the second midpoint to the first midpoint. An illumination optical unit defines an optical axis which is arranged perpendicularly to the plane and intersects the plane at an intersection point. The light source is imaged toward infinity by the illumination optical unit. The first individual light source has an extent along the axial direction. The midpoint is offset by an amount (Δ) in a positive direction along the axial direction relative to the intersection. The relationship 0.1*L1≦Δ≦1*L1 is satisfied for the offset.

摘要翻译： 用于光学观察装置的照明装置具有包括布置在平面中的第一单独光源和第二单独光源的光源。 第一单独光源具有第一中点，而第二单独光源具有第二中点。 轴向方向由从第二中点到第一中点的矢量定义。 照明光学单元限定垂直于该平面配置的光轴，并且在交叉点处与平面相交。 光源通过照明光学单元向无穷远成像。 第一单独的光源具有沿着轴向的程度。 中点相对于交叉点沿轴向的正方向偏移量（Δ）。 偏移量满足关系式为0.1 *L1≤Δ≤1* L1。

公开(公告)号：US20170020733A1

公开(公告)日：2017-01-26

申请号：US15131518

申请日：2016-04-18

申请人： CARL ZEISS MEDITEC AG

发明人： Mark BENDETT ,  Mark Bischoff ,  Mario Gerlach ,  Dirk Mühlhoff

IPC分类号： A61F9/008 ,  B23K26/0622

CPC分类号： A61F9/00827 ,  A61F9/00836 ,  A61F2009/00865 ,  A61F2009/00868 ,  A61F2009/0087 ,  A61F2009/00872 ,  A61F2009/00874 ,  B23K26/0624

摘要： A method for precise working of material, particularly organic tissue, comprises the step of providing laser pulses with a pulse length between 50 fs and 1 ps and with a pulse frequency from 50 kHz to 1 MHz and with a wavelength between 600 and 2000 nm for acting on the material to be worked. Apparatus, in accordance with the invention, for precise working of material, particularly organic tissue comprising a pulsed laser, wherein the laser has a pulse length between 50 fs and 1 ps and with a pulse frequency of from 50 kHz to 1 MHz is also described.

摘要翻译： 材料，特别是有机组织的精确加工的方法包括以下步骤：提供脉冲长度在50fs和1ps之间，脉冲频率为50kHz至1MHz，波长在600和2000nm之间的激光脉冲 对待工作的材料采取行动。 还描述了根据本发明的用于精确加工材料，特别是包括脉冲激光的有机组织的装置，其中激光器具有在50fs和1ps之间的脉冲长度以及50kHz至1MHz的脉冲频率 。

公开(公告)号：US09543107B2

公开(公告)日：2017-01-10

申请号：US14239188

申请日：2012-08-14

申请人： Frank Weigand

发明人： Frank Weigand

IPC分类号： H01J35/08 ,  A61N5/10

CPC分类号： H01J35/08 ,  A61N5/1001 ,  A61N2005/1022

摘要： The present invention relates in particular to methods and apparatuses for generating and/or providing X-ray radiation with specific radiation characteristics, in particular with a specific radiation dose rate curve (10). In order to provide simple and cost efficient solution, it is provided according to the invention, that the X-ray radiation is generated and/or provided, by composing and/or adapting the X-ray radiation with the specific radiation characteristics, in particular with the specific radiation dose rate curve (10), proportionally from a first specification X-ray radiation with a defined first radiation characteristics, in particular with a predetermined first radiation dose rate curve (11) and a second specification X-ray radiation, which is different from the first specification X-ray radiation, with defined second radiation characteristics, in particular with a predetermined second radiation dose rate curve (12).

摘要翻译： 本发明特别涉及用于产生和/或提供具有特定辐射特征的X射线辐射的方法和装置，特别是与特定辐射剂量率曲线（10）。 为了提供简单且具有成本效益的解决方案，根据本发明提供了通过组合和/或适应具有特定辐射特性的X射线辐射来生成和/或提供X射线辐射，特别是 具有特定辐射剂量率曲线（10），与具有确定的第一辐射特性的第一规格X射线辐射成比例地，特别是具有预定的第一辐射剂量率曲线（11）和第二规格X射线辐射，其中 与具有限定的第二辐射特性的第一规格X射线辐射不同，特别是具有预定的第二辐射剂量率曲线（12）。

公开(公告)号：US09510730B2

公开(公告)日：2016-12-06

申请号：US14228896

申请日：2014-03-28

申请人： Optiscan Pty Ltd. ,  Carl Zeiss Surgical GmbH ,  Carl Zeiss Meditec Inc.

发明人： Hans-Joachim Miesner ,  Christoph Hauger ,  Werner Nahm ,  Frank Rudolph ,  Guido Hattendorf ,  Peter M. Delaney ,  John D. Allen

IPC分类号： A61B1/04 ,  A61B1/07 ,  A61B1/00 ,  A61B7/02 ,  A61B1/313 ,  A61B5/00 ,  A61B5/06 ,  G02B21/00 ,  G02B23/24 ,  A61B1/06 ,  A61B1/227 ,  A61B1/233 ,  A61B1/267 ,  A61B8/12

CPC分类号： A61B1/00078 ,  A61B1/00009 ,  A61B1/00041 ,  A61B1/00045 ,  A61B1/0005 ,  A61B1/0008 ,  A61B1/00172 ,  A61B1/042 ,  A61B1/06 ,  A61B1/227 ,  A61B1/233 ,  A61B1/267 ,  A61B1/313 ,  A61B5/0066 ,  A61B5/0068 ,  A61B5/0075 ,  A61B5/0084 ,  A61B5/064 ,  A61B5/065 ,  A61B5/6835 ,  A61B5/6852 ,  A61B5/6855 ,  A61B7/02 ,  A61B8/12 ,  A61B90/90 ,  A61B90/92 ,  A61B90/94 ,  G02B21/0028 ,  G02B23/2476

摘要： An imaging apparatus and method are provided. The probe for an imaging apparatus includes a manually manipulable proximal portion; a straight distal portion with a distal tip for locating at a site to define an observational field; and a curved portion between the proximal portion and the distal portion. The imaging method includes the steps of locating a distal tip of an imaging probe at a site to define an observational field; irradiating the observational field from the distal tip; and collecting a return signal at the distal tip; wherein the probe comprises a manually manipulable proximal portion. The apparatus and method provided herein are useful for various applications including but not limited to endomicroscopy and other microsurgical procedures performed under optical stereoscopic magnified visualization, such as neurosurgery, ENT/facial surgery and spinal surgery.

摘要翻译： 提供了一种成像装置和方法。 用于成像装置的探针包括手动可操纵的近端部分; 具有远端的直的远端部分，用于定位在现场以限定观察场; 以及在近端部分和远端部分之间的弯曲部分。 该成像方法包括以下步骤：将成像探针的远侧末端定位在位置以限定观察场; 从远端照射观察场; 并在远端收集返回信号; 其中所述探针包括可手动操作的近端部分。 本文提供的装置和方法可用于各种应用，包括但不限于在光学立体放大显微镜（例如神经外科手术，ENT /面部手术和脊柱手术）下执行的内窥镜和其他显微外科手术。

公开(公告)号：US09504607B2

公开(公告)日：2016-11-29

申请号：US13696266

申请日：2011-05-05

申请人： Christoph Russmann

发明人： Christoph Russmann

IPC分类号： A61N5/06 ,  A61F9/008

CPC分类号： A61F9/008 ,  A61F2009/00842 ,  A61F2009/00857 ,  A61F2009/00872

摘要： A method and device to stabilize the cornea with fewer adverse effects. In particular, a greater stability and shorter treatment time are to be made possible. To this end, the cornea is locally irradiated successively at different sites so that collagen fibers are indirectly or directly crosslinked at the irradiated sites. In this way, the collagen fibers are advantageously crosslinked in a spatially resolved manner. Accordingly, the entire eye need not be irradiated with tissue-damaging UV light, and regions having a weaker structure can be locally stabilized selectively. The sites of the cornea are preferably irradiated so that the collagen fibers are ionized in each instance by photoabsorption of a plurality of photons which each have an energy below an ionizing energy of a given molecule. After a short treatment period, strong covalent bonds are formed directly between the collagen fibers. Crosslinking agents need not be used.

摘要翻译： 一种以较少的不良反应来稳定角膜的方法和装置。 特别地，可以实现更大的稳定性和更短的处理时间。 为此，角膜在不同部位连续局部照射，使得胶原纤维在照射部位间接或直接交联。 以这种方式，胶原纤维有利地以空间分辨的方式交联。 因此，整个眼睛不需要用组织损伤的紫外线照射，并且具有较弱结构的区域可以选择性地局部稳定。 角膜的部位优选被照射，使得胶原纤维在每种情况下通过多个光子的光吸收而离子化，每个光子的能量低于给定分子的电离能。 在短暂的治疗期后，在胶原纤维之间直接形成强共价键。 无需使用交联剂。

公开(公告)号：US09498120B2

公开(公告)日：2016-11-22

申请号：US14579678

申请日：2014-12-22

申请人： Abouzar Eslami ,  Corinna Maier-Matic ,  Falk Hartwig ,  Christine Kochwagner

发明人： Abouzar Eslami ,  Corinna Maier-Matic ,  Falk Hartwig ,  Christine Kochwagner

IPC分类号： A61B3/10 ,  A61B8/08 ,  A61B3/00 ,  A61B8/10 ,  A61B3/12 ,  A61B3/13 ,  A61F9/007 ,  A61B5/00

CPC分类号： A61B3/102 ,  A61B3/0025 ,  A61B3/0058 ,  A61B3/12 ,  A61B3/13 ,  A61B5/0051 ,  A61B5/0066 ,  A61B5/0073 ,  A61B5/0097 ,  A61B8/10 ,  A61B8/12 ,  A61B8/485 ,  A61F9/00736

摘要： A system and method for optical coherence elastography of tissue of an eye. The method includes introducing a probe into the eye, the probe including a vibration element, generating time resolved images of the tissue of the eye located posterior the vibration element of the probe by optical coherence tomography, exciting the vibration element to ultrasonic vibrations making the tissue vibrate or oscillate, measuring a displacement of the tissue in the time resolved images, and calculating elasticity values of the tissue from the displacement.

摘要翻译： 用于眼睛组织的光学相干弹性成像的系统和方法。 该方法包括将探针引入到眼睛中，探针包括振动元件，通过光学相干断层扫描产生位于探针的振动元件后面的眼睛组织的时间分辨图像，激励振动元件以使超声振动，使组织 振动或振荡，测量时间分辨图像中组织的位移，以及从位移计算组织的弹性值。