公开(公告)号：US07844348B2

公开(公告)日：2010-11-30

申请号：US11463286

申请日：2006-08-08

Applicant: John M. Swoyer ,  Allison M. Kidder ,  Jeffrey Sweber ,  Scott Brainard ,  Valerie Glazier

Inventor： John M. Swoyer ,  Allison M. Kidder ,  Jeffrey Sweber ,  Scott Brainard ,  Valerie Glazier

IPC: A61N1/05

CPC classification number: A61B5/0084 ,  A61B1/00165 ,  A61B5/04 ,  A61N1/0509 ,  A61N1/0551 ,  A61N1/0558 ,  A61N1/0573 ,  A61N1/0587

Abstract: Devices and methods for placing medical leads using minimally invasive techniques. One lead includes a lead body connected to a lead head having an aperture for providing fiber optic access to the interior of a helical electrode. The fiber optic shaft may be disposed within or along-side a drive shaft releasably coupled to the head to rotate the head. The drive shaft and lead body may be delivered using a delivery catheter. The delivery catheter can be advanced though a small incision to the target tissue site, and the site remotely visualized through the fiber optic scope extending through the lead head aperture. Some catheters include a distal mapping electrode readable from the catheter proximal portion or handle. The lead head can be rotated, rotating the helical electrode into the tissue, and the catheter, drive shaft, and fiber optic probe removed. In one use, epicardial pacing leads are placed on the posterior surface of the heart, aided by visualization and mapping to obtain optimal electrode placement and patient outcome.

Abstract translation: 使用微创技术放置医疗线的设备和方法。 一个引线包括连接到具有用于提供到螺旋电极的内部的光纤访问的孔的引导头的引线体。 光纤轴可以设置在可释放地联接到头部的驱动轴内或侧面，以旋转头部。 驱动轴和引线体可以使用输送导管输送。 输送导管可以通过小切口前进到目标组织部位，并且通过穿过引导头孔的光纤镜片远程可视化部位。 一些导管包括可从导管近端部分或手柄读取的远端映射电极。 引导头可以旋转，将螺旋电极旋转到组织中，导管，驱动轴和光纤探针被移除。 在一次使用中，通过可视化和映射辅助，将心外膜起搏引线放置在心脏的后表面上，以获得最佳电极放置和患者结果。

公开(公告)号：US20100198312A1

公开(公告)日：2010-08-05

申请号：US12707084

申请日：2010-02-17

Applicant: Robert A. Stevenson ,  Warren S. Dabney ,  Robert Shawn Johnson ,  Holly Noelle Moschiano ,  Henry R. Halperin

Inventor： Robert A. Stevenson ,  Warren S. Dabney ,  Robert Shawn Johnson ,  Holly Noelle Moschiano ,  Henry R. Halperin

IPC: A61N1/08

CPC classification number: H03H1/00 ,  A61N1/05 ,  A61N1/086 ,  A61N1/37 ,  A61N1/3718 ,  G01R33/285 ,  G01R33/288 ,  H03H1/0007 ,  H03H7/0115 ,  H03H7/1766 ,  H03H2001/0092 ,  H03H2007/013

Abstract: A bandstop filter having optimum component values is provided for a lead of an active implantable medical device (AIMD). The bandstop filter includes a capacitor in parallel with an inductor. The parallel capacitor and inductor are placed in series with the implantable lead of the AIMD, wherein values of capacitance and inductance are selected such that the bandstop filter is resonant at a selected frequency. The Q of the inductor may be relatively maximized and the Q of the capacitor may be relatively minimized to reduce the overall Q of the bandstop filter to attenuate current flow through the implantable lead along a range of selected frequencies.

Abstract translation: 为有源可植入医疗装置（AIMD）的引线提供具有最佳分量值的带阻滤波器。 带阻滤波器包括与电感器并联的电容器。 并联电容器和电感器与AIMD的可植入引线串联放置，其中选择电容和电感值，使得带阻滤波器以选定的频率谐振。 电感器的Q可以相对最大化，并且电容器的Q可以被相对最小化，以减小带阻滤波器的总体Q，以衰减沿着所选频率的范围通过可植入引线的电流。

公开(公告)号：US20100189879A1

公开(公告)日：2010-07-29

申请号：US12756516

申请日：2010-04-08

Applicant: Robert C. O'Brien

Inventor： Robert C. O'Brien

IPC: B05D7/00 ,  C23C14/34 ,  B29C35/08

CPC classification number: A61N1/056 ,  A61N1/0551 ,  C23C14/562 ,  Y10T428/2913

Abstract: Implantable electrical lead wires, such as cobalt-chromium-molybdenum alloy wires, are coated with a metal, ceramic, or carbon to a thickness of about 100 nm or less to provide a non-reactive interface to polyurethane sheathing materials. Preferred is sputter coating an amorphous carbon intermediate the alloy wire and the polyurethane sheath.

Abstract translation: 诸如钴 - 铬 - 钼合金线的可植入电引线被涂覆有约100nm或更小的厚度的金属，陶瓷或碳，以提供与聚氨酯护套材料的非反应性界面。 优选在合金丝和聚氨酯护套之间溅射涂覆无定形碳。

公开(公告)号：US07765005B2

公开(公告)日：2010-07-27

申请号：US11097999

申请日：2005-03-31

Applicant: Robert A. Stevenson

Inventor： Robert A. Stevenson

IPC: A61N1/375

CPC classification number: A61N1/3754 ,  A61N1/086 ,  A61N1/37 ,  A61N1/3718 ,  H01F17/06 ,  H01F2017/065 ,  H01F2017/067 ,  H01G4/35 ,  H03H2001/0042 ,  H03H2001/0057

Abstract: A feedthrough terminal assembly for an active implantable medical device (AIMD) includes a plurality of leadwires extending from electronic circuitry of the AIMD, and a lossy ferrite inductor through which the leadwires extend in non-conductive relation for increasing the impedance of the leadwires at selected RF frequencies and reducing magnetic flux core saturation of the lossy ferrite inductor through phase cancellation of signals carried by the leadwires. A process is also provided for filtering electromagnetic interference (EMI) in an implanted leadwire extending from an AIMD into body fluids or tissue, wherein the leadwire is subjected to occasional high-power electromagnetic fields such as those produced by medical diagnostic equipment including magnetic resonance imaging.

Abstract translation: 用于有源可植入医疗设备（AIMD）的馈通终端组件包括从AIMD的电子电路延伸的多条引线，以及有损铁氧体电感器，引线在非导电关系中延伸，以增加选定的引线的阻抗 RF频率，并通过引线引出的信号的相位消除来减小有损铁氧体电感的磁通量饱和度。 还提供了一种过程，用于过滤从AIMD延伸到体液或组织中的植入引线中的电磁干扰（EMI），其中引线经受偶尔的高功率电磁场，例如由医学诊断设备产生的包括磁共振成像 。

公开(公告)号：US20100160997A1

公开(公告)日：2010-06-24

申请号：US12686137

申请日：2010-01-12

Applicant: Robert Shawn Johnson ,  Warren S. Dabney ,  Robert A. Stevenson ,  Christopher Michael Williams ,  Holly Noelle Moschiano ,  Scott Brainard ,  Daniel Robert Kaiser ,  Henry R. Halperin ,  Albert C. Lardo

Inventor： Robert Shawn Johnson ,  Warren S. Dabney ,  Robert A. Stevenson ,  Christopher Michael Williams ,  Holly Noelle Moschiano ,  Scott Brainard ,  Daniel Robert Kaiser ,  Henry R. Halperin ,  Albert C. Lardo

IPC: A61N1/375 ,  A61N1/05 ,  A61B18/14

CPC classification number: G01R33/285 ,  A61B5/042 ,  A61B5/055 ,  A61B5/7203 ,  A61B2018/00839 ,  A61B2090/374 ,  A61N1/05 ,  A61N1/086 ,  A61N1/3718 ,  B82Y30/00

Abstract: An energy management system facilitates the transfer of high frequency energy coupled into an implanted lead at a selected RF frequency or frequency band, to an energy dissipating surface. This is accomplished by conductively coupling the implanted lead to the energy dissipating surface through an energy diversion circuit including one or more passive electronic network components whose impedance characteristics are at least partially tuned to the implanted lead's impedance characteristics.

Abstract translation: 能量管理系统有助于以选定的RF频率或频带将耦合到植入引线中的高频能量传输到能量消散表面。 这是通过将植入的导线导电地耦合到能量消散表面来实现的，该能量分流电路包括一个或多个无源电子网络部件，其阻抗特性至少部分地被调整到植入引线的阻抗特性。

公开(公告)号：US20100134951A1

公开(公告)日：2010-06-03

申请号：US12563919

申请日：2009-09-21

Applicant: Richard L. Brendel ,  Robert A. Stevenson ,  Jason Woods

Inventor： Richard L. Brendel ,  Robert A. Stevenson ,  Jason Woods

IPC: H01G4/35 ,  H01G13/00 ,  H01R43/16

CPC classification number: H01G4/228 ,  A61N1/3718 ,  A61N1/3754 ,  H01G4/35 ,  Y10T29/435 ,  Y10T29/49204

Abstract: A discoidal feedthrough capacitor has its active electrode plates disposed within a dielectric body so that an edge of the active electrode plates is exposed at a surface of a through-hole for a conductive lead. The conductive lead is conductively coupled to the exposed edge of the electrode plates without an intervening conductive termination surface. Similarly, a ground electrode plate set of the feedthrough capacitor may have an edge exposed at the outer periphery of the capacitor for conductively coupling the exposed edge of the ground electrode plate to a conductive ferrule without an intervening conductive termination surface.

Abstract translation: 盘状馈通电容器的有源电极板设置在电介质体内，使得有源电极板的边缘暴露在用于导电引线的通孔的表面上。 导电引线导电地耦合到电极板的暴露边缘，而没有中间的导电端接表面。 类似地，旁路电容器的接地电极板组可以在电容器的外周具有暴露的边缘，用于将接地电极板的暴露边缘导电耦合到导电套圈，而没有中间的导电端接表面。

公开(公告)号：US07729781B2

公开(公告)日：2010-06-01

申请号：US11686322

申请日：2007-03-14

Applicant: John M. Swoyer ,  Jeffrey S. Gagnon

Inventor： John M. Swoyer ,  Jeffrey S. Gagnon

IPC: A61N1/05

CPC classification number: A61N1/0551 ,  A61N1/0529 ,  A61N1/0536

Abstract: Devices and methods for stimulating nerves, such as peripheral nerves are described. Some devices can include small cross-section lead bodies having one or more electrodes in the round distal portion, the electrodes having a substantially planar surface within the distal portion of the lead which is suitable for placement through a cylindrical needle intended to access a spinal region of a patient. Some lead electrodes are covered with a hydrophilic coating at least about 0.001 inches thick. The hydrophilic coating may include a steroid and/or a GABA (gamma-aminobutyric acid) agonist which can elute or diffuse over time, away from the electrode.

Abstract translation: 描述了用于刺激神经的装置和方法，例如外周神经。 一些装置可以包括在圆形远端部分中具有一个或多个电极的小横截面引线体，电极在引线的远端部分内具有基本平坦的表面，该表面适于通过旨在进入脊柱区域的圆柱形针头 的病人 一些引线电极被至少约0.001英寸厚的亲水涂层覆盖。 亲水涂层可以包括类固醇和/或GABA（γ-氨基丁酸）激动剂，它可随时间洗脱或扩散，远离电极。

公开(公告)号：US07722787B2

公开(公告)日：2010-05-25

申请号：US09757519

申请日：2001-01-09

Applicant: Craig R. Horne ,  Sujeet Kumar ,  James P. Buckley ,  Xiangxin Bi

Inventor： Craig R. Horne ,  Sujeet Kumar ,  James P. Buckley ,  Xiangxin Bi

IPC: H01B1/02

CPC classification number: H01B1/122 ,  B82Y30/00 ,  C01G31/00 ,  C01G31/02 ,  C01P2002/72 ,  C01P2004/04 ,  C01P2004/51 ,  C01P2004/54 ,  C01P2004/62 ,  C01P2004/64 ,  H01M4/136 ,  H01M4/58 ,  H01M4/62 ,  H01M2004/021 ,  Y10T428/2982

Abstract: Metal vanadium oxide particles have been produced with an average diameter less than about 500 nm. The particles are produced from nanocrystalline vanadium oxide particles. Silver vanadium oxide particles, for example, can be formed by the heat treatment of a mixture of nanoscale vanadium oxide and a silver compound. Other metal vanadium oxide particles can be produced by similar processes. The metal vanadium oxide particles have very uniform properties.

Abstract translation: 已经生产了平均直径小于约500nm的金属氧化钒颗粒。 颗粒由纳米晶体氧化钒颗粒制成。 例如，可以通过对纳米级钒氧化物和银化合物的混合物进行热处理来形成银氧化钒颗粒。 其他金属氧化钒颗粒可以通过类似的方法生产。 金属氧化钒颗粒具有非常均匀的性质。

公开(公告)号：US07645538B1

公开(公告)日：2010-01-12

申请号：US11209150

申请日：2005-08-22

Applicant: Paul T. Hallifax ,  David Warchocki ,  James Ditzel ,  Gary Freitag

Inventor： Paul T. Hallifax ,  David Warchocki ,  James Ditzel ,  Gary Freitag

IPC: H01M2/36 ,  H01M2/38

CPC classification number: H01M6/32 ,  H01M2/361 ,  H01M2/365 ,  H01M6/16

Abstract: The present invention is directed to any electrochemical cell casing design having an electrolyte fill aperture. The electrolyte fill aperture receives and directs the electrolyte into the casing. A fill plug has at least two components—an insert section detachably connected to a placement unit. The placement unit allows a user to properly position the insert section into the electrolyte fill aperture. Once this is done, the placement unit is detached from the insert section. The insert section in then hermetically sealed to the casing. If desired, the fill plug can be used for filling the electrolyte in the casing.

Abstract translation: 本发明涉及具有电解质填充孔的任何电化学电池壳体设计。 电解质填充孔接收并引导电解质进入外壳。 填充塞具有至少两个部件 - 插入部分可拆卸地连接到放置单元。 放置单元允许使用者将插入部分适当地定位到电解质填充孔中。 一旦完成，则放置单元与插入部分分离。 插入部分然后气密地密封到壳体。 如果需要，填充塞可以用于在壳体中填充电解质。

公开(公告)号：US20090312835A1

公开(公告)日：2009-12-17

申请号：US12477422

申请日：2009-06-03

Applicant: Robert A. Stevenson

Inventor： Robert A. Stevenson

IPC: A61M1/12 ,  H05K7/00 ,  A61N1/375 ,  A61N1/362 ,  A61N1/39 ,  A61M5/14 ,  B65B31/00

CPC classification number: A61N1/375 ,  A61M1/122 ,  A61M5/14276 ,  A61M2207/00 ,  A61M2209/045 ,  A61N1/08 ,  A61N1/37 ,  A61N1/3925

Abstract: Active implantable medical devices (AIMDs) are backfilled with a dielectric fluid to increase the volts per mil dielectric breakdown strength between internal circuit elements. In a method for backfilling the AIMD with dielectric fluid, substantially all air and moisture is evacuated from the AIMD housing prior to backfilling the AIMD housing with a dielectric fluid having a dielectric breakdown strength greater than air, nitrogen or helium. The AIMD is constructed to accommodate volumetric expansion or contraction of the dielectric fluid due to changes of pressure or temperature of the dielectric fluid to maintain integrity of the AIMD.

Abstract translation: 有源植入式医疗设备（AIMD）用电介质流体回填，以增加内部电路元件之间的密度介电击穿强度。 在用介质流体回填AIMD的方法中，在用具有大于空气，氮或氦的介电击穿强度的介电流体回填AIMD外壳之前，基本上所有的空气和水分都从AIMD壳体中排出。 AIMD被构造成适应由于介电流体的压力或温度的变化而导致的介电流体的体积膨胀或收缩，以保持AIMD的完整性。