公开(公告)号：US09675478B2

公开(公告)日：2017-06-13

申请号：US14302295

申请日：2014-06-11

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Stephen D. Pacetti ,  Ni Ding

IPC: A61F2/91 ,  A61F2/82 ,  A61F2/90 ,  A61L31/06

CPC classification number: A61F2/90 ,  A61L31/06

Abstract: Methods of making polymeric devices, such as stents, using solvent based processes. More particularly, methods of making bioabsorbable stents.

公开(公告)号：US09610387B2

公开(公告)日：2017-04-04

申请号：US15170618

申请日：2016-06-01

Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

Inventor： Syed F. A. Hossainy ,  Stephen D. Pacetti

IPC: C08G63/00 ,  A61L31/14 ,  A61L31/06 ,  C08J3/18 ,  C08K5/00 ,  B29C45/72 ,  C08G63/02 ,  B29K67/00 ,  B29L31/00

CPC classification number: A61L31/141 ,  A61L31/06 ,  A61L31/148 ,  A61L2400/00 ,  B29C45/0053 ,  B29C45/72 ,  B29C71/0009 ,  B29C71/02 ,  B29C2071/0027 ,  B29C2071/022 ,  B29K2033/04 ,  B29K2067/04 ,  B29L2031/753 ,  C08J3/18 ,  C08J9/00 ,  C08J2207/10 ,  C08J2300/16 ,  C08K5/0016

Abstract: Methods of making polymeric devices, such as stents, with one or more modifications such as addition of plasticizers, to improve processing, and the devices made by these methods.

公开(公告)号：US20170049592A1

公开(公告)日：2017-02-23

申请号：US14831693

申请日：2015-08-20

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Stephen D. Pacetti ,  Chad J. Abunassar ,  Diem U. Ta ,  Richard J. Rapoza

IPC: A61F2/89 ,  B29C69/00 ,  B29C49/42 ,  A61F2/82 ,  A61F2/915

CPC classification number: B29C69/001 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91575 ,  A61F2230/0006 ,  A61F2250/0036 ,  A61F2250/0098 ,  B29C49/4268 ,  B29C2793/0063 ,  B29L2031/7546

Abstract: A scaffold strut is shaped to improve hemocompatibility. The scaffold is made from a tube having variable wall thickness. Methods are disclosed for modifying the thickness of the tube in such a way as to achieve a reduced hemodynamic profile, but without significantly affecting strength properties in areas where stress concentrations exist when the scaffold is loaded.

Abstract translation: 支架支架的形状可改善血液相容性。 支架由具有可变壁厚的管制成。 公开了用于改变管的厚度的方法，以便实现减少的血流动力学特征，但是当支架被装载时，在存在应力集中的区域中没有显着影响强度性质。

公开(公告)号：US09566666B2

公开(公告)日：2017-02-14

申请号：US13802189

申请日：2013-03-13

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Stephen D. Pacetti ,  Joel Harrington

IPC: B23K26/38 ,  A61F2/91 ,  A61F2/915 ,  B23K26/40

CPC classification number: A61F2/915 ,  A61F2/91 ,  A61F2002/91558 ,  A61F2002/91583 ,  A61F2240/001 ,  B23K26/38 ,  B23K26/402 ,  B23K2103/42 ,  B23K2103/50 ,  B29C35/0805 ,  B29C2035/0838 ,  B29K2067/00 ,  B29K2105/005 ,  B29K2105/258 ,  B29K2995/006 ,  B29L2031/7532

Abstract: A method of laser machining a polymer construct to form a stent that includes a bioresorbable polymer and an absorber that increases absorption of laser energy during laser machining. The laser cuts the tubing at least in part by a multiphoton absorption mechanism and the polymer and absorber have a very low absorbance or are transparent to light at the laser wavelength.

Abstract translation: 激光加工聚合物构造物以形成支架的方法，所述支架包括生物可再吸收聚合物和在激光加工期间增加激光能量吸收的吸收体。 激光至少部分地通过多光子吸收机构切割管道，并且聚合物和吸收体具有非常低的吸光度或对于激光波长的光是透明的。

公开(公告)号：US20160303295A1

公开(公告)日：2016-10-20

申请号：US15192973

申请日：2016-06-24

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Lothar KLEINER ,  Syed F.A. Hossainy ,  Mikael Trollsas ,  Stephen D. Pacetti

IPC: A61L31/14 ,  A61L31/16 ,  A61L31/10

CPC classification number: A61L31/148 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/41 ,  A61L2300/416 ,  A61L2300/42 ,  A61L2420/02 ,  A61L2420/08 ,  C08L67/04

Abstract: The present invention provides an absorbable coating for an implantable device and the methods of making and using the same.

Abstract translation: 本发明提供了一种用于可植入装置的可吸收涂层及其制造和使用方法。

公开(公告)号：US09387282B2

公开(公告)日：2016-07-12

申请号：US14182211

申请日：2014-02-17

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Lothar W. Kleiner ,  Syed F. A. Hossainy ,  Mikael Trollsas ,  Stephen D. Pacetti

IPC: A61F2/00 ,  A61L31/10 ,  A61L31/14 ,  A61L31/16

CPC classification number: A61L31/148 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/41 ,  A61L2300/416 ,  A61L2300/42 ,  A61L2420/02 ,  A61L2420/08 ,  C08L67/04

Abstract: The present invention provides an absorbable coating for an implantable device and the methods of making and using the same.

Abstract translation: 本发明提供了一种用于可植入装置的可吸收涂层及其制造和使用方法。

公开(公告)号：US09345597B2

公开(公告)日：2016-05-24

申请号：US13937921

申请日：2013-07-09

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Stephen D. Pacetti

IPC: A61F2/06 ,  A61F2/89 ,  A61L31/18 ,  A61F2/915

CPC classification number: A61F2/90 ,  A61F2/844 ,  A61F2/89 ,  A61F2/915 ,  A61F2230/0069 ,  A61F2250/0071 ,  A61F2250/0096 ,  A61F2250/0098 ,  A61L31/18

Abstract: An implantable sent comprises a radiopaque marker that provides a structural connection between two parts made of a polymer substrate material. The two parts can be one bending element of one radially expandable ring and another bending element of an adjacent expandable ring. The two parts can be two bending elements of the same radially expandable ring. The radiopaque marker can be in the form of an entire radially expandable ring.

Abstract translation: 可植入的包括不透射线的标记，其提供由聚合物基底材料制成的两个部分之间的结构连接。 两个部件可以是一个可径向扩张的环的一个弯曲元件和相邻可膨胀环的另一个弯曲元件。 两个部件可以是同一径向可扩张环的两个弯曲元件。 不透射线的标记可以是整个可径向扩张的环的形式。

公开(公告)号：US20160113790A1

公开(公告)日：2016-04-28

申请号：US14985141

申请日：2015-12-30

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Stephen D. Pacetti

IPC: A61F2/91

CPC classification number: A61F2/91 ,  A23G9/283 ,  A61F2240/001 ,  A61F2250/0068 ,  B05D1/18 ,  B05D3/0486 ,  B05D3/0493 ,  B05D7/22

Abstract: An apparatus for loading material into a stent strut can comprise a cover sleeve. The cover sleeve is elastic so that it can reduce in diameter so as to press against the stent strut, and expand in diameter so as to be spaced apart from the stent strut. The stent strut can include a lumen into which material is injected. When pressed against the stent strut, the cover sleeve seals side openings to the lumen and prevents injected material from leaking out of the side openings during the injection process.

Abstract translation: 用于将材料装载到支架支柱中的装置可以包括盖套筒。 盖套是弹性的，使得其可以减小直径以便压靠支架支柱，并且直径扩大以与支架支柱间隔开。 支架支架可以包括注射材料的内腔。 当压靠支架支柱时，盖套筒将侧开口密封到内腔，并防止在注射过程中注入材料从侧开口泄漏出来。

公开(公告)号：US20150328373A1

公开(公告)日：2015-11-19

申请号：US14281811

申请日：2014-05-19

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Stephen D. Pacetti ,  Xiao Ma

IPC: A61L31/10 ,  B05D1/18 ,  A61L31/14

CPC classification number: A61L31/10 ,  A61L31/06 ,  A61L31/14 ,  A61L31/141 ,  A61L31/148 ,  A61L2300/802 ,  A61L2400/18 ,  A61L2420/02 ,  A61L2420/06 ,  B05D1/18 ,  B05D2254/00 ,  C08L67/04

Abstract: Methods of making biodegradable polymeric devices, such as stents, with one or more modifications to alter the degradation rate, and the biodegradable polymeric devices are described. Modifications include blending of two polymers, one with a different degradation rate, inclusion of additives to alter the degradation rate, and the use of polymers of a high polydispersity.

Abstract translation: 描述了制造具有改变降解速率的一个或多个修饰物的可生物降解的聚合物装置（例如支架）和可生物降解的聚合物装置的方法。 修饰包括混合两种聚合物，一种具有不同的降解速率，包含添加剂以改变降解速率，以及使用高分散度的聚合物。

公开(公告)号：US20150290363A1

公开(公告)日：2015-10-15

申请号：US14251536

申请日：2014-04-11

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Stephen D. Pacetti ,  O. Mikael Trollsas ,  Alexander J. Sheehy

IPC: A61L31/10 ,  A61L31/16 ,  A61L33/12 ,  A61L31/08

CPC classification number: A61L31/10 ,  A61L31/08 ,  A61L31/16 ,  A61L33/128 ,  A61L2300/252 ,  A61L2300/42 ,  A61L2420/02 ,  C08L89/00

Abstract: Coatings for medical devices, the coatings including albumin, the methods of forming the coatings, and the coated medical devices are disclosed. In preferred embodiments the medical device is a bioabsorbable stent. The albumin coating layer improves the thromboresistance of the device.

Abstract translation: 公开了用于医​​疗装置的涂层，包括白蛋白的涂层，形成涂层的方法和涂覆的医疗装置。 在优选实施例中，医疗装置是生物可吸收支架。 白蛋白涂层改善了该装置的血栓阻力。